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Kytril (Granisetron Hydrochloride) - Published Studies

 
 



Kytril Related Published Studies

Well-designed clinical trials related to Kytril (Granisetron)

Comparison of an extended-release formulation of granisetron (APF530) versus palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with moderately or highly emetogenic chemotherapy: results of a prospective, randomized, double-blind, noninferiority phase 3 trial. [2015]

Randomized, double-blind, crossover study of palonosetron compared with granisetron for the prevention of chemotherapy-induced nausea and vomiting in a Chinese population. [2011.03]

Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study. [2011]

Dexamethasone with either granisetron or ondansetron for postoperative nausea and vomiting in laparoscopic surgery. [2010.02]

Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron. [2010.01]

Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. [2010.01]

Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. [2010]

Pharmacokinetics of a granisetron transdermal system for the treatment of chemotherapy-induced nausea and vomiting. [2009.12]

Double-blind comparison of granisetron, promethazine, or a combination of both for the prevention of postoperative nausea and vomiting in females undergoing outpatient laparoscopies. [2009.11]

Combination therapy in the prevention of PONV after strabismus surgery in children: granisetron, ondansetron, midazolam with dexamethasone. [2009.10]

A randomized, double-blinded comparison of ondansetron, granisetron, and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. [2009.07]

Randomized controlled study comparing two doses of intravenous granisetron (1 and 3 mg) for acute chemotherapy-induced nausea and vomiting in cancer patients: a non-inferiority trial. [2009.07]

Does granisetron eliminate the gag reflex? A crossover, double-blind, placebo-controlled pilot study. [2009.03]

Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. [2008.11.21]

Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. [2008.08.21]

Is ondansetron more effective than granisetron for chemotherapy-induced nausea and vomiting? A review of comparative trials. [2007.12]

The effectiveness of inhalation isopropyl alcohol vs. granisetron for the prevention of postoperative nausea and vomiting. [2007.12]

Is ondansetron more effective than granisetron for chemotherapy-induced nausea and vomiting? A review of comparative trials. [2007.12]

Intramuscular injection of granisetron into the masseter muscle increases the pressure pain threshold in healthy participants and patients with localized myalgia. [2007.07]

Granisetron versus ondansetron treatment for breakthrough postoperative nausea and vomiting after prophylactic ondansetron failure: a pilot study. [2007.06]

Prevention of postoperative nausea and vomiting in patients undergoing laparoscopic bariatric surgery--granisetron alone vs granisetron combined with dexamethasone/droperidol. [2007.06]

The prophylactic granisetron does not prevent postdelivery nausea and vomiting during elective cesarean delivery under spinal anesthesia. [2007.03]

A comparison of cyclizine and granisetron alone and in combination for the prevention of postoperative nausea and vomiting. [2006.11]

Rapid determination of granisetron in human plasma by liquid chromatography coupled to tandem mass spectrometry and its application to bioequivalence study. [2006.10.11]

The use of oral granisetron versus intravenous ondansetron for antiemetic prophylaxis in patients undergoing laparoscopic surgery: the effect on emetic symptoms and quality of recovery. [2006.05]

Prevention of postoperative nausea and vomiting with granisetron and dolasetron in relation to CYP2D6 genotype. [2006.04]

Age-related differences in metoclopramide requirement for pain on injection of propofol. [2006]

Comparison of ramosetron and granisetron for the prevention of acute and delayed emesis in Cisplatin-based chemotherapy: a randomized controlled trial. [2005.12]

A randomized, double-blind study of granisetron plus dexamethasone versus ondansetron plus dexamethasone to prevent postoperative nausea and vomiting in patients undergoing abdominal hysterectomy. [2005.11]

The efficacy of granisetron for cancer patients undergoing platinum-based chemotherapy: comparison of 1 miligram versus 3 miligram doses in preventing nausea and vomiting. [2005.10]

Effects of granisetron with droperidol or dexamethasone on prevention of postoperative nausea and vomiting after general anesthesia for cesarean section. [2005.09]

Alprazolam significantly improves the efficacy of granisetron in the prophylaxis of emesis secondary to moderately emetogenic chemotherapy in patients with breast cancer. [2005.08]

Comparative clinical study of the anti-emetic effects of oral ramosetron and injected granisetron in patients with malignant glioma undergoing ACNU chemotherapy. [2005.06]

The effects of ondansetron and granisetron on electrocardiography in children receiving chemotherapy for acute leukemia. [2005.04]

The effect on mechanical pain threshold over human muscles by oral administration of granisetron and diclofenac-sodium. [2005.02]

Granisetron and ondansetron for prevention of nausea and vomiting in patients undergoing modified radical mastectomy. [2004.12]

Granisetron vs ondansetron for prevention of nausea and vomiting in hematopoietic stem cell transplant patients: results of a prospective, double-blind, randomized trial. [2004.12]

Effects of granisetron in the treatment of nausea and vomiting after laparoscopic cholecystectomy: a dose-ranging study. [2004.07]

Benefits and risks of granisetron versus ramosetron for nausea and vomiting after breast surgery: a randomized, double-blinded, placebo-controlled trial. [2004.07]

A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use. [2004.05]

Does increasing the steroid dose enhance the efficacy of the antiemetic combination of granisetron and methylprednisolone in gynecologic cancer patients--a randomized study. [2004.03.15]

Efficacy of prophylactic intravenous granisetron in postoperative emesis in adults. [2004]

[Preventive effects of ramosetron and granisetron in prevention of gastrointestinal reaction associated with chemotherapeutic agents: a comparative study] [2003.12.10]

A double-blind, crossover, randomized comparison of granisetron and ramosetron for the prevention of acute and delayed cisplatin-induced emesis in patients with gastrointestinal cancer: is patient preference a better primary endpoint? [2003.12]

A comparison of granisetron, droperidol, and metoclopramide in the treatment of established nausea and vomiting after breast surgery: a double-blind, randomized, controlled trial. [2003.04]

Pain on injection of propofol: the effect of granisetron pretreatment. [2003.03]

Granisetron versus granisetron/dexamethasone combination for the treatment of nausea, retching, and vomiting after major gynecologic surgery: a randomized, double-blind study. [2003.02]

A randomized double-blind trial to compare the clinical efficacy of granisetron with metoclopramide, both combined with dexamethasone in the prophylaxis of chemotherapy-induced delayed emesis. [2003.02]

Granisetron plus dexamethasone versus granisetron alone in the prevention of vomiting induced by conditioning for stem cell transplantation: a prospective randomized study. [2003.01]

Comparison of granisetron and granisetron plus dexamethasone for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. [2003.01]

Combination therapy with granisetron, methylprednisolone and droperidol as an antiemetic prophylaxis in CDDP-induced delayed emesis for gynecologic cancer. [2003]

[Clinical observation of granisetron in preventing postoperative nausea and vomiting following supratentorial craniotomy] [2002.12.28]

Comparative study of low-dose oral granisetron plus dexamethasone and high-dose metoclopramide plus dexamethasone in prevention of nausea and vomiting induced by CHOP-therapy in young patients with non-Hodgkin's lymphoma. [2002.11]

Prophylactic antiemetic efficacy of granisetron or ramosetron in patients undergoing thyroidectomy. [2002.10]

Clinical comparison of the selective serotonin3 antagonists ramosetron and granisetron in treating acute chemotherapy-induced emesis, nausea and anorexia. [2002.09]

Comparison of granisetron with granisetron plus droperidol combination prophylaxis in post-operative nausea and vomiting after laparoscopic cholecystectomy. [2002.09]

Treatment of vomiting after paediatric strabismus surgery with granisetron, droperidol, and metoclopramide. [2002.09]

Antiemetic effects of granisetron, droperidol and dexamethasone in otologic surgery. [2002.07]

Ramosetron for the prevention of cisplatin-induced acute emesis: a prospective randomized comparison with granisetron. [2002.05]

Comparison of granisetron and ramosetron for the prevention of nausea and vomiting after thyroidectomy. [2002.05]

Preoperative oral granisetron for the prevention of vomiting following paediatric surgery. [2002.03]

Effective cross-over to granisetron after failure to ondansetron, a randomized double blind study in patients failing ondansetron plus dexamethasone during the first 24 hours following highly emetogenic chemotherapy. [2001.10.19]

Comparison of tropisetron and granisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy. [2001.09]

A placebo-controlled, crossover trial of granisetron in SRI-induced sexual dysfunction. [2001.06]

Ramosetron compared with granisetron for the prevention of vomiting following strabismus surgery in children. [2001.06]

Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist, MK-869, in combination with granisetron and dexamethasone or with dexamethasone alone. [2001.03.15]

Preoperative oral granisetron for the prevention of postoperative nausea and vomiting after breast surgery. [2001.03]

Comparison of granisetron, droperidol, and metoclopramide for prevention of postoperative vomiting in children with a history of motion sickness undergoing tonsillectomy. [2001.03]

Prevention of vomiting after tonsillectomy in children: granisetron versus ramosetron. [2001.02]

Prophylaxis with oral granisetron for the prevention of nausea and vomiting after laparoscopic cholecystectomy: a prospective randomized study. [2001.01]

The efficacy and safety of once-daily Kytril (granisetron hydrochloride) tablets in the prophylaxis of nausea and emesis following fractionated upper abdominal radiotherapy. [2001]

Double-blind comparative trial of oral ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation. [2001]

Immediate effects of the serotonin antagonist granisetron on temporomandibular joint pain in patients with systemic inflammatory disorders. [2000.12.22]

Randomized, multicenter comparison of oral granisetron and oral ondansetron for emetogenic chemotherapy. [2000.11]

Comparison of the efficacy and safety of oral granisetron plus dexamethasone with intravenous ondansetron plus dexamethasone to control nausea and vomiting induced by moderate/severe emetogenic chemotherapy. [2000.10]

Double-blind, randomized, parallel-group study on the efficacy and safety of oral granisetron and oral ondansetron in the prophylaxis of nausea and vomiting in patients receiving hyperfractionated total body irradiation. [2000.07]

Randomised double blind crossover study comparing ondansetron, granisetron and tropisetron. A cost-benefit analysis. [2000.07]

Granisetron/dexamethasone combination for the prevention of postoperative nausea and vomiting after thyroidectomy. [2000.06]

Antiemetic efficacy of single-dose oral granisetron (1 mg vs 2 mg) with moderately emetogenic chemotherapy. [2000.05]

Comparative efficacy of three 5-HT3 antagonists (granisetron, ondansetron, and tropisetron) plus dexamethasone for the prevention of cisplatin-induced acute emesis: a randomized crossover study. [2000.04]

[Oral granisetron solution as prophylaxis for chemotherapy-induced emesis in children: double-blind study of 2 doses] [2000.03]

Granisetron, tropisetron, and ondansetron in the prevention of acute emesis induced by a combination of cisplatin-Adriamycin and by high-dose ifosfamide delivered in multiple-day continuous infusions. [2000.03]

Randomized clinical trial of granisetron, droperidol and metoclopramide for the treatment of nausea and vomiting after laparoscopic cholecystectomy. [2000.03]

Efficacy and safety of oral granisetron versus i.v. granisetron in patients undergoing peripheral blood progenitor cell and bone marrow transplantation. [2000.02]

Comparison of granisetron, ondansetron and tropisetron for control of vomiting and nausea induced by cisplatin. [2000.02]

Effect of propranolol and granisetron on experimentally induced pain and allodynia/hyperalgesia by intramuscular injection of serotonin into the human masseter muscle. [2000.02]

Granisetron/dexamethasone combination for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. [2000.01]

Granisetron, droperidol, and metoclopramide for the treatment of established postoperative nausea and vomiting in women undergoing gynecologic surgery. [2000.01]

Oral granisetron for the prevention of acute late onset nausea and vomiting in patients treated with moderately emetogenic chemotherapy. [2000]

Prevention of nausea and vomiting after middle ear surgery: granisetron versus ramosetron. [1999.12]

Double-blind comparative study of droperidol, granisetron and granisetron plus dexamethasone as prophylactic anti-emetic therapy in patients undergoing abdominal, gynaecological, breast or otolaryngological surgery. [1999.11]

Prevention of post-operative nausea and vomiting with combined granisetron and droperidol in women undergoing thyroidectomy. [1999.10]

Ramosetron vs granisetron for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. [1999.10]

Preoperative oral granisetron for the prevention of vomiting after strabismus surgery in children. [1999.09]

Comparison of ramosetron and granisetron for preventing postoperative nausea and vomiting after gynecologic surgery. [1999.08]

A randomised dose-comparison trial of granisetron in preventing emesis in children with leukaemia receiving emetogenic chemotherapy. [1999.07]

Granisetron plus or minus alprazolam for emesis prevention in chemotherapy of lymphomas: a randomized multicenter trial. Granisetron Trialists Group. [1999.07]

Prophylactic therapy with combined granisetron and dexamethasone for the prevention of post-operative vomiting in children. [1999.06]

Granisetron/dexamethasone combination for reducing nausea and vomiting during and after spinal anesthesia for cesarean section. [1999.06]

[Efficacy of combination with granisetron and methylprednisolone for nausea, vomiting and appetite loss in remission induction chemotherapy of acute myeloid leukemia--a randomized comparative trial between granisetron alone and granisetron plus methylprednisolone] [1999.05]

Granisetron compared with prednisolone plus metopimazine as anti-emetic prophylaxis during multiple cycles of moderately emetogenic chemotherapy. [1999.05]

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