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Levoxyl (Levothyroxine Sodium) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Adverse reactions associated with levothyroxine therapy are primarily those of hyperthyroidism due to therapeutic overdosage. They include the following:

General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating;

Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia;

Musculoskeletal: tremors, muscle weakness;

Cardiac: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest;

Pulmonary: dyspnea;

GI: diarrhea, vomiting, abdominal cramps;

Dermatologic: hair loss, flushing;

Reproductive: menstrual irregularities, impaired fertility.

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.

Seizures have been reported rarely with the institution of levothyroxine therapy.

Inadequate levothyroxine dosage will produce or fail to ameliorate the signs and symptoms of hypothyroidism.

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

In addition to the above events, the following have been reported, predominately when Levoxyl tablets were not taken with water: choking, gagging, tablet stuck in throat and dysphagia (see Information for Patients).



REPORTS OF SUSPECTED LEVOXYL SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Levoxyl. The information is not vetted and should not be considered as verified clinical evidence.

Possible Levoxyl side effects / adverse reactions in 68 year old female

Reported by a physician from Japan on 2011-10-17

Patient: 68 year old female

Reactions: Thinking Abnormal, Depressed Level of Consciousness, Status Epilepticus, Memory Impairment

Adverse event resulted in: hospitalization

Suspect drug(s):
Levoxyl



Possible Levoxyl side effects / adverse reactions in 54 year old female

Reported by a consumer/non-health professional from United States on 2011-10-31

Patient: 54 year old female

Reactions: Pharyngeal Oedema, Drug Hypersensitivity, Urticaria, Rash

Suspect drug(s):
Acetaminophen
    Dosage: unk

Gabapentin
    Dosage: 600 mg, unk

Levoxyl
    Dosage: unk

Other drugs received by patient: Tylenol-500; Proventil Gentlehaler; Zocor; Ventolin; Benadryl



Possible Levoxyl side effects / adverse reactions in 59 year old female

Reported by a consumer/non-health professional from United States on 2011-11-10

Patient: 59 year old female weighing 104.3 kg (229.5 pounds)

Reactions: Overdose, Hyperthyroidism, Arrhythmia

Adverse event resulted in: hospitalization

Suspect drug(s):
Levoxyl



See index of all Levoxyl side effect reports >>

Drug label data at the top of this Page last updated: 2013-11-06

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