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Lexuss (Codeine Phosphate / Chlorpheniramine Maleate) - Summary



Each 5 mL (1 teaspoonful) of vanilla cream flavored liquid for oral administration contains:

  •  10 mg Codeine Phosphate
  •    2 mg Chlorpheniramine Maleate

Lexuss (Codeine/Chlorpheniramine) is indicated for the following:

Temporarily relieves runny nose and alleviates sneezing, itching of the nose or throat, and itchy watery eyes due to hay fever or allergic rhinitis; for the temporary control of cough due to minor throat and bronchial irritation associated with the common cold or inhaled irritants; calms the cough control center and relieves coughing.

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Published Studies Related to Lexuss (Codeine / Chlorpheniramine)

Preparation and in vitro release of dual-drug resinate complexes containing codeine and chlorpheniramine. [2011.02]
OBJECTIVE: To develop the dual-drug resinate complexes containing codeine and chlorpheniramine with a novel batch processing, characterize the dual-drug resinate complexes, and study its drug release behavior in vitro... CONCLUSION: The dual-drug resinate complexes were formed through the reaction between the drugs and the IERs by chemical bond. The release behavior of the drug from the dual-drug resinate complexes in vitro was mainly correlated with the drug molecular structure, the eluting ionic strength, composition, and ionic strength of the release media. The novel dual-drug resinate complexes could be used to deliver two drugs in one therapeutic dose.

Preparation of codeine-resinate and chlorpheniramine-resinate sustained-release suspension and its pharmacokinetic evaluation in beagle dogs. [2007.06]
Using ion exchange resins (IERs) as carriers, a dual-drug sustained release suspension containing codeine, and chlorpheniramine had been prepared to elevate drug safety, effectiveness and conformance. The codeine resinate and chlorpheniramine resinate beads were prepared by a batch process and then impregnated with Polyethylene glycol 4000 (PEG 4000), respectively...

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Page last updated: 2011-12-09

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