Lidoderm (Lidocaine Patch) - Summary

LIDODERM SUMMARY

LIDODERM (lidocaine patch 5%) is comprised of an adhesive material containing 5% lidocaine, which is applied to a non-woven polyester felt backing and covered with a polyethylene terephthalate (PET) film release liner. The release liner is removed prior to application to the skin. The size of the patch is 10 cm × 14 cm.

LIDODERM is indicated for relief of pain associated with post-herpetic neuralgia. It should be applied only to intact skin.

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NEWS HIGHLIGHTS

Published Studies Related to Lidoderm (Lidocaine Patch)

Treatment for postoperative wound pain in gynecologic laparoscopic surgery: topical lidocaine patches. [2012]
CONCLUSIONS: Topical lidocaine patches at the laparoscopic port sites reduced

Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial. [2012]
non-inferior to subcutaneous local anaesthetic... CONCLUSIONS: Both the lidocaine/tetracaine patch and subcutaneous injection of

Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. [2011.03]
This study evaluated the effects of topical lidocaine on skin sensation and on intradermal capsaicin-induced pain and hyperalgesia. A randomized, double-blinded, placebo controlled methodology was used...

Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. [2011]
This study evaluated the effects of topical lidocaine on skin sensation and on intradermal capsaicin-induced pain and hyperalgesia. A randomized, double-blinded, placebo controlled methodology was used...

Lidocaine/tetracaine medicated plaster: in minor dermatological and needle puncture procedures. [2010.11.12]
The lidocaine/tetracaine medicated plaster comprises a lidocaine/tetracaine 70 mg/70 mg patch and a controlled heat-assisted drug delivery pod that increases the diffusion of lidocaine and tetracaine into the dermis. Following a 1-hour application period, systemic absorption of lidocaine or tetracaine from the plaster was minimal...

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Clinical Trials Related to Lidoderm (Lidocaine Patch)

Tumescent Lidocaine Maximum Safe mg/kg Dosage [Enrolling by invitation]
This pharmacokinetic clinical trial is a dose ranging study of lidocaine in tumescent local anesthesia. The goal is to understand the absorption pharmacokinetic of tumescent lidocaine and to determine an objective (statistical) estimate of the maximum safe mg/kg dosage of lidocaine in tumescent local anesthesia without liposuction.

Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain [Completed]
Patients with moderate to severe chronic Low Back Pain (LBP) despite current analgesic treatment participated in a Phase IV clinical trial to evaluate the analgesic efficacy of the lidocaine patch 5% compared to placebo in treating moderate to severe chronic LBP.

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions [Completed]
Patients with postherpetic neuralgia (PHN), diabetic neuropathy (DN), complex regional pain syndrome (CRPS), carpal tunnel syndrome, HIV neuropathy, idiopathic sensory neuropathy, or other peripheral neuropathy participated in a Phase IV clinical trial to assess the comparative efficacy and safety of Lidoderm monotherapy versus gabapentin monotherapy in treating a diverse group of peripheral neuropathic pain patients.

Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee [Completed]
Patients with knee pain due to Osteoarthritis (OA) experiencing sub-optimal pain relief from their current analgesic regimen will participate in a pilot clinical trial to evaluate the effectiveness and tolerability of the Lidoderm Patch compared with placebo in treating knee pain from OA.

Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving [Recruiting]
We propose that the systemic administration of lidocaine following the induction of cue-induced craving, relative to saline plus cue-induced craving or lidocaine without cue-induced craving, will block the reconsolidation of cue memories. This will lead to a reduction in cue-induced craving upon repeated testing as well as subsequent cocaine use and basal craving.

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Reports of Suspected Lidoderm (Lidocaine Patch) Side Effects

Drug Ineffective (7),  Death (6),  Muscular Weakness (6),  Oedema Peripheral (5),  Contusion (4),  Drug Hypersensitivity (4),  Paraesthesia (4),  Swelling (4),  Weight Decreased (3),  Constipation (3), more >>