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Lidopen (Lidocaine Hydrochloride) - Side Effects and Adverse Reactions



The following types of systemic reactions have been reported with lidocaine hydrochloride administration:

  1. Central Nervous System: light-headedness; drowsiness; dizziness; apprehension; euphoria; tinnitus; blurred or double vision; vomiting; sensations of heat, cold or numbness; twitching; tremors; convulsions; unconsciousness; respiratory depression and arrest.
  2. Cardiovascular System: hypotension; bradycardia; cardiovascular collapse and cardiac arrest.
  3. Allergic reactions may occur but are infrequent. There have been no reports of cross-sensitivity between lidocaine hydrochloride and procainamide or between lidocaine hydrochloride and quinidine.

Soreness at the injection site following intramuscular injection has occasionally been reported.


  1. In the case of severe reaction, do not continue or repeat administration of the drug.
  2. Institute emergency resuscitative procedures including maintenance of patent airway and cardiopulmonary resuscitation, if required.
  3. For severe convulsions, parenteral administration of a rapidly acting anticonvulsant may be used by persons appropriately trained in the use of those drugs and the management of the cardiovascular and respiratory depression which may result. Resuscitative equipment should be available.
Drug label data at the top of this Page last updated: 2008-04-25

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