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Lincocin (Lincomycin) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The following reactions have been reported with the use of lincomycin:

Gastrointestinal

Glossitis, stomatitis, nausea, vomiting, antibiotic-associated diarrhea and colitis, and pruritus ani. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS).

Hematopoietic

Neutropenia, leukopenia, agranulocytosis and thrombocytopenic purpura have been reported. There have been rare reports of aplastic anemia and pancytopenia in which LINCOCIN could not be ruled out as the causative agent.

Hypersensitivity Reactions

Hypersensitivity reactions such as angioneurotic edema, serum sickness and anaphylaxis have been reported. Rare instances of erythema multiforme, some resembling Stevens-Johnson syndrome, have been associated with LINCOCIN. If an allergic reaction to LINCOCIN occurs, discontinue the drug. Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures, including oxygen, intravenous fluids, intravenous antihistamines, corticosteroids, pressor amines, and airway management, as clinically indicated.

Skin and Mucous Membranes

Skin rashes, urticaria and vaginitis and rare instances of exfoliative and vesiculobullous dermatitis have been reported.

Liver

Although no direct relationship of LINCOCIN to liver dysfunction has been established, jaundice and abnormal liver function tests (particularly elevations of serum transaminase) have been observed.

Renal

Although no direct relationship of lincomycin to renal damage has been established, renal dysfunction as evidenced by azotemia, oliguria, and/or proteinuria has been observed in rare instances.

Cardiovascular

After too rapid intravenous administration, rare instances of cardiopulmonary arrest and hypotension have been reported. (See DOSAGE AND ADMINISTRATION.)

Special Senses

Tinnitus and vertigo have been reported occasionally.

Local Reactions

Patients have demonstrated excellent local tolerance to intramuscularly administered LINCOCIN. Reports of pain following injection have been infrequent. Intravenous administration of LINCOCIN in 250 to 500 mL of 5% dextrose injection or 0.9% sodium chloride injection produced no local irritation or phlebitis.



REPORTS OF SUSPECTED LINCOCIN SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Lincocin. The information is not vetted and should not be considered as verified clinical evidence.

Possible Lincocin side effects / adverse reactions in 61 year old female

Reported by a physician from Italy on 2011-10-11

Patient: 61 year old female

Reactions: Dyspnoea, Angioedema, Oral Disorder, Urticaria, Oedema

Adverse event resulted in: hospitalization

Suspect drug(s):
Ketoprofen
    Dosage: 1 unit dose, daily
    Administration route: Oral
    Indication: Tooth Abscess
    Start date: 2011-08-23
    End date: 2011-08-23

Lincocin
    Dosage: 1 unit dose, daily
    Indication: Tooth Abscess
    Start date: 2011-08-23
    End date: 2011-08-23

Other drugs received by patient: Lansoprazole



Possible Lincocin side effects / adverse reactions in 84 year old female

Reported by a pharmacist from Japan on 2011-10-28

Patient: 84 year old female

Reactions: Electrocardiogram QT Prolonged

Suspect drug(s):
Lincocin



Possible Lincocin side effects / adverse reactions in 84 year old female

Reported by a pharmacist from Japan on 2011-11-11

Patient: 84 year old female

Reactions: Electrocardiogram QT Prolonged

Suspect drug(s):
Lincocin

Garenoxacin Mesylate



See index of all Lincocin side effect reports >>

Drug label data at the top of this Page last updated: 2007-08-20

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