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Lithium Carbonate (Lithium Carbonate) - Description and Clinical Pharmacology

 
 



Rx Only

DESCRIPTION

Each capsule for oral administration contains 150 mg, 300 mg or 600 mg of lithium carbonate. In addition, each capsule contains the following inactive ingredient:

150 mg: Talc.

300 mg: Talc.

600 mg: Colloidal Silicon Dioxide, Stearic Acid and Talc.

Capsule shell for the 150 mg potency contains: Gelatin and Titanium Dioxide.

Capsule shell for the 300 mg potency contains: D&C Yellow #10, FD&C Green #3, FD&C Red #40, FD&C Yellow #6, Gelatin and Titanium Dioxide.

Capsule shell for the 600 mg potency contains: Titanium Dioxide, Gelatin and FD&C Red #40.

The printing ink contains: D&C Yellow #10, FD&C Blue #1, FD&C Blue #2, FD&C Red #40, n-Butyl Alcohol, Pharmaceutical Glaze, Propylene Glycol, SDA-3A Alcohol, and Synthetic Black Iron Oxide.

Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94 and an emission line at 671 nm on the flame photometer.

Lithium Carbonate is a white, light, alkaline powder with molecular formula Li2CO3 and molecular weight 73.89.

CLINICAL PHARMACOLOGY

Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown.

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