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Meperidine (Meperidine Hydrochloride) - Indications and Dosage



Meperidine hydrochloride tablets are indicated for the relief of moderate to severe pain.


For Relief of Pain

Dosage should be adjusted according to the severity of the pain and the response of the patient. Meperidine is less effective orally than on parenteral administration. The dose of meperidine hydrochloride should be proportionately reduced (usually by 25 to 50 percent) when administered concomitantly with phenothiazines and many other tranquilizers since they potentiate the action of meperidine hydrochloride.

Adults: The usual dosage is 50 mg to 150 mg orally, every 3 or 4 hours as necessary.

Pediatric Patients: The usual dosage is 1.1 mg/kg to 1.8 mg/kg orally, up to the adult dose, every 3 or 4 hours as necessary.


Meperidine Hydrochloride tablets are dosage forms that contain meperidine hydrochloride which is a controlled substance. Like morphine, meperidine is controlled under Schedule II of the Controlled Substances Act. Meperidine, like all opioids, is liable to diversion and misuse and should be handled accordingly. Patients and their families should be instructed to flush any meperidine hydrochloride tablets that are no longer needed.

Meperidine hydrochloride tablets has been targeted for theft and diversion by criminals. Healthcare professionals should contact their State Professional Licensing Board or State Controlled Substance Authority for information on how to prevent and detect abuse or diversion of this product.


Meperidine hydrochloride tablets, 50 mg are white to off-white, round, biconvex tablets, debossed 467 on one side and scored on the other side.

Bottles of 100s          NDC 57664-467-08

Meperidine hydrochloride tablets, 100 mg are white to off-white, round, biconvex tablets, debossed 471 on one side and plain on the other side.

Bottles of 100s          NDC 57664-471-08

Store at 20° to 25°C (68° to 77°F). [see USP Controlled Room Temperature].

Dispense in tight, light resistant containers as defined in USP.

Manufactured by:                                                                         C.S.No.: 5256T06
Caraco Pharmaceutical Laboratories, Ltd.                                            Iss.: 07/09
1150 Elijah McCoy Drive
Detroit, MI 48202

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