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Meprobamate (Meprobamate) - Description and Clinical Pharmacology

 
 



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DESCRIPTION

Meprobamate is a white powder with a characteristic odor and a bitter taste. It is slightly soluble in water, freely soluble in acetone and alcohol, and sparingly soluble in ether. The structural formula of meprobamate is:

C<sub>9</sub>H<sub>18</sub>N<sub>2</sub>O<sub>4</sub>                 M.W. 218.25

C9H18N2O4                 M.W. 218.25

Meprobamate Tablets USP, 200 mg and 400 mg for oral administration contain the following inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, and stearic acid.

CLINICAL PHARMACOLOGY

Meprobamate is a carbamate derivative which has been shown in animal studies to have effects at multiple sites in the central nervous system including the thalamus and limbic system.

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