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Methimazole (Methimazole) - Indications and Dosage

 
 



INDICATIONS AND USAGE

Methimazole is indicated in the medical treatment of hyperthyroidism. Long-term therapy may lead to remission of the disease. Methimazole may be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy. Methimazole is also used when thyroidectomy is contraindicated or not advisable.

DOSAGE AND ADMINISTRATION

Methimazole is administered orally. It is usually given in 3 equal doses at approximately 8-hour intervals.

Adults

The initial daily dosage is 15 mg for mild hyperthyroidism, 30 to 40 mg for moderately severe hyperthyroidism, and 60 mg for severe hyperthyroidism, divided into 3 doses at 8-hour intervals. The maintenance dosage is 5 to 15 mg daily.

Pediatric

Initially, the daily dosage is 0.4 mg/kg of body weight divided into 3 doses and given at 8-hour intervals. The maintenance dosage is approximately 1/2 of the initial dose.

HOW SUPPLIED


Methimazole Tablets, USP 10 mg - round, white to off white bi-convex tablet. Debossed HP bisect 71 on one side and plain on the reverse side.

They are available in:

Bottles of 100 NDC 23155-071-01
Bottles of 1000 NDC 23155-071-10

Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].

Dispense in tight, light-resistant container.

Manufactured for:

Heritage Pharmaceuticals Inc.
Edison, NJ 08837
1.866.901.DRUG (3784)


Issued 10/11

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