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Mucomyst (Acetylcysteine Inhalation) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Adverse effects have included stomatitis, nausea, vomiting, fever, rhinorrhea, drowsiness, clamminess, chest tightness, and bronchoconstriction. Clinically overt acetylcysteine induced bronchospasm occurs infrequently and unpredictably even in patients with asthmatic bronchitis or bronchitis complicating bronchial asthma.

Acquired sensitization to acetylcysteine has been reported rarely. Reports of sensitization in patients have not been confirmed by patch testing. Sensitization has been confirmed in several inhalation therapists who reported a history of dermal eruptions after frequent and extended exposure to acetylcysteine.

Reports of irritation to the tracheal and bronchial tracts have been received and although hemoptysis has occurred in patients receiving acetylcysteine such findings are not uncommon in patients with bronchopulmonary disease and a causal relationship has not been established.

ADVERSE REACTIONS

Oral administration of acetylcysteine, especially in the large doses needed to treat acetaminophen overdose, may result in nausea, vomiting and other gastrointestinal symptoms. Rash with or without mild fever has been observed rarely.



REPORTS OF SUSPECTED MUCOMYST SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Mucomyst. The information is not vetted and should not be considered as verified clinical evidence.

Possible Mucomyst side effects / adverse reactions in 91 year old male

Reported by a consumer/non-health professional from United States on 2011-11-15

Patient: 91 year old male weighing 69.0 kg (151.8 pounds)

Reactions: Haemorrhage, Atrial Fibrillation

Suspect drug(s):
Coumadin
    Indication: Atrial Fibrillation
    Start date: 2009-10-01
    End date: 2010-10-01

Diltiazem HCL
    Indication: Atrial Fibrillation
    Start date: 2009-10-01
    End date: 2010-10-01

Mucomyst

Simvastatin

Plavix
    Start date: 2011-10-10

Other drugs received by patient: Mucomyst; Ventolin; Duoneb; Aspirin; Multaq



Possible Mucomyst side effects / adverse reactions in 74 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-13

Patient: 74 year old female

Reactions: Haemorrhage, Drug Interaction

Adverse event resulted in: hospitalization

Suspect drug(s):
Mucomyst

Other drugs received by patient possibly interacting with the suspect drug:
Cordarone
    Dosage: 200.0 mg, 4x/wk
    Administration route: Oral
    Start date: 2002-09-17

Roxithromycin
    Dosage: 300 mg, 1x/day
    Administration route: Oral
    Start date: 2002-12-13
    End date: 2002-12-16

Levothyroxine Sodium
    Dosage: 100 ug, 1x/day
    Administration route: Oral
    Start date: 2002-09-17

Previscan
    Dosage: 10.0 mg, 1x/day
    Administration route: Oral
    Start date: 2002-12-07
    End date: 2002-12-15

Voltaren
    Dosage: 100.0 mg, 1x/day
    Administration route: Oral
    Start date: 2002-11-30
    End date: 2002-12-16

Previscan
    Dosage: 5.0 mg, 1x/day
    Administration route: Oral
    Start date: 2002-12-16
    End date: 2002-12-16

Atorvastatin Calcium
    Dosage: 2 df, 1x/day
    Administration route: Oral
    Start date: 2002-09-17

Other drugs received by patient: Lasix; Ultra-Levure; Tramadol HCL; Amitriptyline HCL; Noctamid-1; Omeprazole; Fluconazole; Kayexalate; Ramipril



Possible Mucomyst side effects / adverse reactions in 67 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-10

Patient: 67 year old male

Reactions: Rhabdomyolysis, Hyperthermia, Shock Haemorrhagic, Bronchitis, Acute Respiratory Failure, Renal Failure Acute

Adverse event resulted in: hospitalization

Suspect drug(s):
Oxazepam
    Dosage: 50 mg, 2x/day
    Administration route: Oral
    Start date: 2003-04-14
    End date: 2003-09-12

Mucomyst
    Dosage: 200 mg, 3x/day
    Administration route: Oral
    Start date: 2003-09-08
    End date: 2003-09-12

Metformin HCL
    Dosage: 280 mg, 2x/day
    Administration route: Oral
    Start date: 2003-04-14
    End date: 2003-09-12

Rulid
    Dosage: 150 mg, 2x/day
    Administration route: Oral
    Start date: 2003-09-08
    End date: 2003-09-12

Pravastatin
    Dosage: 40 mg, 1x/day
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2003-09-12

Surmontil
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Start date: 2003-04-14
    End date: 2003-09-12

Bisoprolol Fumarate
    Dosage: 2.5 mg, 2x/day
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2003-09-12

Pantoprazole
    Dosage: 40 mg, 1x/day
    Administration route: Oral
    Start date: 2003-04-14
    End date: 2003-09-12

Noctamid
    Dosage: 2 mg, 1x/day
    Administration route: Oral
    Start date: 2003-09-08
    End date: 2003-09-12

Previscan
    Dosage: 1 df, 3x/day
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2003-09-12

Zestril
    Dosage: 5 mg, 2x/day
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2002-09-12

Repaglinide
    Dosage: 2 mg - frequency unspecified
    Administration route: Oral
    Start date: 2003-04-14
    End date: 2003-09-12

Acetaminophen
    Dosage: 1 df, 4x/day
    Administration route: Oral
    Start date: 2003-09-08
    End date: 2003-09-12



See index of all Mucomyst side effect reports >>

Drug label data at the top of this Page last updated: 2006-10-10

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