Omnipred (Prednisolone Acetate Ophthalmic) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Adverse reactions include, in decreasing order of frequency, elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.

Although systemic effects are extremely uncommon, there have been rare occurrences of systemic hypercorticoidism after use of topical steroids.

Corticosteroid-containing preparations have also been reported to cause acute anterior uveitis and perforation of the globe.

Keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation and ptosis have occasionally been reported following local use of corticosteroids.

The development of secondary ocular infection (bacterial, fungal and viral) has occurred. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. The possibility of fungal invasion should be considered in any persistent corneal ulceration where steroid treatment has been used (SEE WARNINGS ).

REPORTS OF SUSPECTED OMNIPRED SIDE EFFECTS / ADVERSE REACTIONS

Possible Omnipred side effects / adverse reactions in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-27

Patient: 70 year old female weighing 59.0 kg (129.7 pounds)

Reactions: Toxic Anterior Segment Syndrome

Suspect drug(s):
BSS

Nevanac
    Dosage: (ophthalmic)
    Indication: Cataract Operation

Vigamox
    Dosage: (ophthalmic)
    Indication: Cataract Operation

BSS
    Dosage: (intraocular), (intraocular)
    Indication: Cataract Operation
    Start date: 2011-11-15
    End date: 2011-11-15

BSS
    Dosage: (intraocular), (intraocular)
    Indication: Cataract Operation
    Start date: 2011-11-15
    End date: 2011-11-15

Omnipred
    Dosage: (ophthalmic)
    Indication: Cataract Operation

Tetracaine Polygyl Sterile Ophthalmic Solution
    Dosage: (ophthalmic)
    Indication: Cataract Operation

Other drugs received by patient: Betadine

Possible Omnipred side effects / adverse reactions in 66 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-27

Patient: 66 year old male weighing 72.6 kg (159.7 pounds)

Reactions: Toxic Anterior Segment Syndrome

Suspect drug(s):
BSS

Omnipred
    Dosage: ophthalmic
    Indication: Cataract Operation

Tetracaine Polygyl Sterile Ophthalmic Solution
    Dosage: ophthalmic
    Indication: Cataract Operation

BSS
    Dosage: intraocular
    Indication: Cataract Operation
    Start date: 2011-10-14
    End date: 2011-10-14

BSS
    Dosage: intraocular
    Indication: Cataract Operation
    Start date: 2011-10-14
    End date: 2011-10-14

Nevanac
    Dosage: ophthalmic
    Indication: Cataract Operation

Vigamox
    Dosage: ophthalmic
    Indication: Cataract Operation

Other drugs received by patient: Betadine

Possible Omnipred side effects / adverse reactions in 66 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-25

Patient: 66 year old male weighing 72.6 kg (159.7 pounds)

Reactions: OFF Label USE, Toxic Anterior Segment Syndrome

Suspect drug(s):
Tetracaine Polygyl Sterile Ophthalmic Solution
    Dosage: (ophthalmic)
    Start date: 2011-10-14
    End date: 2011-10-14

Omnipred
    Dosage: (ophthalmic)
    Indication: Cataract Operation

Nevanac
    Dosage: (ophthalmic)
    Indication: Cataract Operation

BSS

BSS
    Dosage: (intraocular) ; (intraocular)
    Indication: Cataract Operation
    Start date: 2011-10-14
    End date: 2011-10-14

BSS
    Dosage: (intraocular) ; (intraocular)
    Indication: Cataract Operation
    Start date: 2011-10-14
    End date: 2011-10-14

Vigamox
    Dosage: (ophthalmic)
    Indication: Cataract Operation

Other drugs received by patient: Povidone Iodine