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Optivar (Azelastine Hydrochloride Ophthalmic) - Published Studies

 
 



Optivar Related Published Studies

Well-designed clinical trials related to Optivar (Azelastine Ophthalmic)

MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial of efficacy and safety. [2012]

Two-week comparison study of olopatadine hydrochloride nasal spray 0.6% versus azelastine hydrochloride nasal spray 0.1% in patients with vasomotor rhinitis. [2011.03]

Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device. [2010.08]

Comparison of azelastine versus triamcinolone nasal spray in allergic and nonallergic rhinitis. [2010.01]

Double-blind, placebo-controlled study of azelastine and fluticasone in a single nasal spray delivery device. [2010]

Efficacy and safety of azelastine 0.15% nasal spray and azelastine 0.10% nasal spray in patients with seasonal allergic rhinitis. [2009.11]

Double-blind, placebo-controlled trial of reformulated azelastine nasal spray in patients with seasonal allergic rhinitis. [2009.09]

Efficacy and safety of azelastine 0.15% nasal spray administered once daily in subjects with seasonal allergic rhinitis. [2009.09]

Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis. [2008.01]

Effect of azelastine, montelukast, and their combination on allergen-induced bronchoconstriction in asthma. [2008]

Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis. [2005.05]

Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine. [2004.08]

Histamine skin test reactivity following single and multiple doses of azelastine nasal spray in patients with seasonal allergic rhinitis. [2003.09]

Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine. [2003.08]

Rapid anti-inflammatory action of azelastine eyedrops for ongoing allergic reactions. [2003.04]

Efficacy and safety of topical azelastine compared with topical mitomycin C in patients with allergic conjunctivitis. [2003.04]

Topical azelastine in perennial allergic conjunctivitis. [2003]

Comparison of the efficacy and tolerability of topically administered azelastine, sodium cromoglycate and placebo in the treatment of seasonal allergic conjunctivitis and rhino-conjunctivitis. [2003]

Azelastine eye drops in the treatment of perennial allergic conjunctivitis. [2003]

Effects of intranasal azelastine on the response to nasal allergen challenge. [2002.01]

Evaluation of the efficacy of olopatadine hydrochloride 0.1% ophthalmic solution and azelastine hydrochloride 0.05% ophthalmic solution in the conjunctival allergen challenge model. [2001.08]

Azelastine tablets in the treatment of chronic idiopathic urticaria. Phase iii, randomised, double-blind, placebo and active controlled multicentric clinical trial. [2001.03]

Vasomotor rhinitis: clinical efficacy of azelastine nasal spray in comparison with placebo. [2001.03]

Efficacy of azelastine nasal spray in the treatment of vasomotor (perennial nonallergic) rhinitis. [2001.01]

Treatment of severe seasonal rhinoconjunctivitis by a combination of azelastine nasal spray and eye drops: a double-blind, double-placebo study. [2001]

Comparative efficacy and safety of azelastine and levocabastine nasal sprays in patients with seasonal allergic rhinitis. [2001]

Evaluation of the onset and duration of effect of azelastine eye drops (0.05%) versus placebo in patients with allergic conjunctivitis using an allergen challenge model. [2000.12]

Effect of topical nasal azelastine on the symptoms of rhinitis, sleep, and daytime somnolence in perennial allergic rhinitis. [2000.07]

Investigation of the anti-allergic activity of azelastine on the immediate and late-phase reactions to allergens and histamine using telethermography. [2000.02]

[Acceptability of local treatment of allergic rhinitis with a combination of a corticoid (beclomethasone) and an antihistaminic (azelastine)] [2000]

Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis. [2000]

Sequential therapy with azelastine in seasonal allergic rhinitis. Deutsche Rhinitis Studiengruppe (German Rhinitis Study Group). [1999.11]

Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups. [1999.06]

Histamine and tryptase in nasal lavage fluid after allergen challenge: effect of 1 week of pretreatment with intranasal azelastine or systemic cetirizine. [1999.05]

Azelastine eye drops reduce conjunctival hyperresponsiveness to hyperosmolar glucose challenge in children with asymptomatic mite conjunctivitis. [1999.01]

[Clinical assessment of azelastine nasal spray in seasonal allergic rhinitis] [1998.12]

Effects of azelastine on the level of serum interleukin-4 and soluble CD23 antigen in the treatment of nasal allergy. [1998.12]

[Clinical assessment of azelastine nasal spray in seasonal allergic rhinitis] [1998.12]

Nasal budesonide offers superior symptom relief in perennial allergic rhinitis in comparison to nasal azelastine. [1998.10]

Dose-dependent protection by azelastine eye drops against pollen-induced allergic conjunctivitis. A double-blind, placebo-controlled study. [1998.04]

[Investigation of the efficacy and tolerability of azelastine nasal spray versus ebastine tablets in patients with seasonal allergic rhinitis] [1998.01]

Azelastine eye drops in the treatment of seasonal allergic conjunctivitis or rhinoconjunctivitis in young children. [1998]

The effect of azelastine on the infiltration of inflammatory cells into the bronchial mucosa and clinical changes in patients with bronchial asthma. [1997.11]

Azelastine nasal spray as adjunctive therapy to azelastine tablets in the management of seasonal allergic rhinitis. [1997.10]

Effect of topical applications of budesonide and azelastine on nasal symptoms, eosinophil count and mediator release in atopic patients after nasal allergen challenge during the pollen season. [1997.10]

Seasonal rhinitis and azelastine: long- or short-term treatment? [1997.03]

A randomized double-blind placebo controlled study of azelastine nasal spray in children with perennial rhinitis. [1997.02.14]

Azelastine eye drops reduce and prevent allergic conjunctival reaction and exert anti-allergic activity. [1997.02]

Double-blind, randomised, placebo-controlled study of two concentrations of azelastine eye drops in seasonal allergic conjunctivitis or rhinoconjunctivitis. [1997]

A placebo controlled study comparing the efficacy of intranasal azelastine and beclomethasone in the treatment of seasonal allergic rhinitis. [1997]

Topical azelastine reduces eosinophil activation and intercellular adhesion molecule-1 expression on nasal epithelial cells: an antiallergic activity. [1996.12]

Safety and efficacy of azelastine nasal spray (Astelin NS) for seasonal allergic rhinitis: a 4-week comparative multicenter trial. [1996.02]

Tolerability and pharmacokinetics of single and multiple doses of azelastine hydrochloride in elderly volunteers. [1995.05]

Investigation on the efficacy and tolerance of azelastine (HCL) nasal spray versus ebastine tablets in patients with seasonal allergic rhinitis. [1995.03]

Effect of intranasal azelastine and beclomethasone dipropionate on nasal symptoms, nasal cytology, and bronchial responsiveness to methacholine in allergic rhinitis in response to grass pollens. [1995.02]

Comparison of azelastine nasal spray and oral ebastine in treating seasonal allergic rhinitis. [1995]

A multicenter clinical study of the efficacy and tolerability of azelastine nasal spray in the treatment of seasonal allergic rhinitis: a comparison with oral cetirizine. [1995]

Duration of action of a single dose of azelastine in patients with chronic asthma. [1995]

A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model. [1994.12]

A double-blind, controlled trial to assess the safety and efficacy of azelastine nasal spray in seasonal allergic rhinitis. [1994.11]

Tolerability, pharmacokinetics and dose linearity of azelastine hydrochloride in healthy subjects. [1994.10]

Double-blind assessment of azelastine in the treatment of perennial allergic rhinitis. [1994.08]

Effectiveness of azelastine nasal solution in seasonal allergic rhinitis. [1994.06]

Azelastine nasal spray in the management of seasonal allergic rhinitis. [1994.04]

Comparative efficacy of azelastine nasal spray and terfenadine in seasonal and perennial rhinitis. [1994.03]

A comparison of azelastine nasal spray and cetirizine tablets in the treatment of allergic rhinitis. [1994.01]

The effect of intranasal azelastine and beclomethasone on the symptoms and signs of nasal allergy in patients with perennial allergic rhinitis. [1993.12]

Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis. [1993.10]

A comparison of the efficacy of azelastine nasal spray and loratidine tablets in the treatment of seasonal allergic rhinitis. [1993.09]

Efficacy and tolerability of azelastine nasal spray in patients with allergic rhinitis compared to placebo and budesonide. [1993.08]

Intranasal treatment of perennial allergic rhinitis. Comparison of azelastine nasal spray and budesonide nasal aerosol. [1993.04]

The effect of intranasal azelastine, Rhinolast, on nasal airways obstruction and sneezing following provocation testing with histamine and allergen. [1992.06]

Effect of azelastine on the seasonal increase in non-specific bronchial responsiveness to methacholine in pollen allergic patients. A randomized, double-blind placebo-controlled, crossover study. [1992.03]

The effect of azelastine on the early allergic response. [1992.02]

Azelastine reduces allergen-induced nasal response: a clinical and rhinomanometric assessment. [1992]

Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans. [1991.07]

Dose related protective effect of azelastine on histamine induced bronchoconstriction in extrinsic asthma. [1990.08]

The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma. [1989.11]

Azelastine in the prophylactic treatment of bronchial asthma: an Italian multicentre comparison with ketotifen. [1989.05]

Duration of the effect of a single dose of azelastine on histamine-induced bronchoconstriction. [1989.02]

The in vivo potency and selectivity of azelastine as an H1 histamine-receptor antagonist in human airways and skin. [1988.12]

Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis. [1988.11]

Efficacy of azelastine in perennial allergic rhinitis: clinical and rhinomanometric evaluation. [1988.09]

The effect of azelastine on exercise-induced asthma. [1988.05]

Well-designed clinical trials possibly related to Optivar (Azelastine Ophthalmic)

Solubilized nasal steroid (CDX-947) when combined in the same solution nasal spray with an antihistamine (CDX-313) provides improved, fast-acting symptom relief in patients with allergic rhinitis. [2011.05]

Evaluation of olopatadine hydrochloride nasal spray, 0.6%, used in combination with an intranasal corticosteroid in seasonal allergic rhinitis. [2010.03]

Evaluation of olopatadine hydrochloride nasal spray, 0.6%, used in combination with an intranasal corticosteroid in seasonal allergic rhinitis. [2010]

A comparison of intranasal corticosteroid, leukotriene receptor antagonist, and topical antihistamine in reducing symptoms of perennial allergic rhinitis as assessed through the Rhinitis Severity Score. [2010]

Effects of olopatadine hydrochloride nasal spray 0.6% in the treatment of seasonal allergic rhinitis: a phase III, multicenter, randomized, double-blind, active- and placebo-controlled study in adolescents and adults. [2009.01]

Elucidating the mechanism underlying the ocular symptoms associated with allergic rhinitis. [2008.01]

Efficacy of a steroid nasal spray compared with an antihistamine nasal spray in the treatment of perennial allergic rhinitis. [2000.07]

Clinical efficacy of an antiallergic drug on otitis media with effusion in association with allergic rhinitis. [1999.04]

An endoscopic photographic comparison of nasal drug delivery by aqueous spray. [1998.12]

Differential effects of new-generation H1-receptor antagonists in pruritic dermatoses. [1998.02]

[Perennial rhinitis: antihistaminic and anti-inflammatory treatment] [1997.01]

Acoustic evaluation of the efficacy of medical therapy for allergic nasal obstruction. [1997]

Efficacy of intranasally applied dimethindene maleate solution as spray in adult volunteers with symptoms of seasonal allergic rhinitis in the Vienna challenge chamber. [1996.08]

The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis. [1996]

The effect of antihistamines on the immediate allergic response: a comparative review. [1993.06]

The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma. [1993.06]

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