DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Ovral (Norgestrel) - Side Effects and Adverse Reactions



An increased risk of the following serious adverse reactions (see WARNINGS section for additional information) has been associated with the use of oral contraceptives:

Thromboembolic and thrombotic disorders and other vascular problems (including thrombophlebitis and venous thrombosis with or without pulmonary embolism, mesenteric thrombosis, arterial thromboembolism, myocardial infarction, cerebral hemorrhage, cerebral thrombosis), carcinoma of the reproductive organs and breasts, hepatic neoplasia (including hepatic adenomas or benign liver tumors), ocular lesions (including retinal vascular thrombosis), gallbladder disease, carbohydrate and lipid effects, elevated blood pressure, and headache including migraine.

The following adverse reactions have been reported in patients receiving oral contraceptives and are believed to be drug related (alphabetically listed):



Anaphylactic/anaphylactoid reactions, including urticaria, angioedema, and severe reactions with respiratory and circulatory symptoms

Breakthrough bleeding

Breast changes: tenderness, pain, enlargement, secretion

Budd-Chiari syndrome

Cervical erosion and secretion, change in

Cholestatic jaundice

Chorea, exacerbation of


Corneal curvature (steepening), change in

Diminution in lactation when given immediately post-partum


Edema/fluid retention

Erythema multiforme

Erythema nodosum

Gastrointestinal symptoms (such as abdominal pain, cramps, and bloating)


Intolerance to contact lenses

Libido, changes in

Loss of scalp hair

Melasma/chloasma which may persist

Menstrual flow, change in

Mood changes, including depression




Porphyria, exacerbation of

Rash (allergic)

Serum folate levels, decrease in


Systemic lupus erythematosus, exacerbation of

Temporary infertility after discontinuation of treatment

Vaginitis, including candidiasis

Varicose veins, aggravation of


Weight or appetite (increase or decrease), change in

The following adverse reactions have been reported in users of oral contraceptives:


Cystitis-like syndrome


Hemolytic uremic syndrome

Hemorrhagic eruption

Optic neuritis, which may lead to partial or complete loss of vision


Premenstrual syndrome

Renal function, impaired

Drug label data at the top of this Page last updated: 2006-01-05

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017