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Patanol (Olopatadine Hydrochloride) - Summary



(olopatadine hydrochloride ophthalmic solution) 0.1%

PATANOL® (olopatadine hydrochloride ophthalmic solution) 0.1% is a sterile ophthalmic solution containing olopatadine, a relatively selective H1 -receptor antagonist and inhibitor of histamine release from the mast cell for topical administration to the eyes.

PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is indicated for the treatment of the signs and symptoms of allergic conjunctivitis.

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Published Studies Related to Patanol (Olopatadine)

Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers. [2012]
Since most first-generation antihistamines have undesirable sedative effects on the central nervous systems (CNS), newer (second-generation) antihistamines have been developed to improve patients' quality of life. However, there are few reports that directly compare the antihistaminic efficacy and impairment of psychomotor functions...

Comprehensive report of olopatadine 0.6% nasal spray as treatment for children with seasonal allergic rhinitis. [2011.05]
Allergic rhinitis (AR) is highly prevalent in children...

Two-week comparison study of olopatadine hydrochloride nasal spray 0.6% versus azelastine hydrochloride nasal spray 0.1% in patients with vasomotor rhinitis. [2011.03]
Olopatadine hydrochloride nasal spray 0.6% (OLO) and azelastine nasal spray 137 micrograms (AZE) are effective in treating allergic rhinitis and AZE is indicated for nonallergic vasomotor rhinitis (VMR). This study evaluates the relative safety and efficacy of OLO and AZE in patients with VMR.

Mometasone furoate nasal spray for moderate-to-severe nasal congestion in subjects with seasonal allergic rhinitis. [2011]
Nasal congestion is a frequent, bothersome symptom of seasonal allergic rhinitis (SAR). Mometasone furoate nasal spray (MFNS) has established efficacy in treating nasal allergy symptoms, but no study has been conducted with the primary purpose of evaluating MFNS for relief of congestion...

Olopatadine hydrochloride in children: efficacy and safety for perennial allergic rhinitis. [2010.07]
OBJECTIVE: The efficacy of antihistamines in perennial allergic rhinitis in children has been evaluated in studies using active comparators, whereas placebo-controlled studies are very few. A randomized, multicenter, double-blind, parallel-group clinical study was carried out to evaluate the dose-response relationship and superiority of olopatadine hydrochloride over placebo in children aged 7 to 16 years with perennial allergic rhinitis... CONCLUSIONS: Olopatadine hydrochloride 5 mg twice daily is an effective and safe treatment for perennial allergic rhinitis in children.

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Clinical Trials Related to Patanol (Olopatadine)

Alrex� Versus Patanol in the Treatment of Seasonal Allergic Conjunctivitis(SAC) [Completed]

Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis [Completed]
The purpose of this study is to evaluate an ophthalmic solution for the treatment of ocular itching associated with allergic conjunctivitis using the Conjunctival Allergen Challenge (CAC) model.

Olopatadine Hydrochloride Ophthalmic Solution Study in Chinese Subjects [Recruiting]
The purpose of this study is to evaluate Olopatadine 0. 2% QD (once per day) compared to Olopatadine 0. 1% BID (twice per day) in the treatment of ocular itching associated with allergic conjunctivitis.

Assessing the Efficacy of Maxidex and Patanol for the Treatment of Allergic Conjunctivitis [Completed]
The purpose of this study was to evaluate the efficacy of Maxidex and Patanol compared to placebo in patients with allergic conjunctivitis when exposed to controlled allergen levels in an Environmental Exposure Chamber (EEC).

Study of Olopatadine HCl Ophthalmic Solutions Compared to Vehicle Using the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis in Japanese Subjects [Completed]

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Reports of Suspected Patanol (Olopatadine) Side Effects

Cerebral Infarction (3)Anaphylactoid Reaction (2)Therapeutic Response Increased (1)Nasal Discomfort (1)Abdominal Discomfort (1)Depression (1)Eye Pruritus (1)Osteopenia (1)Eye Pain (1)Ocular Hyperaemia (1)more >>


Based on a total of 1 ratings/reviews, Patanol has an overall score of 8. The effectiveness score is 8 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.

Patanol review by 36 year old female patient

Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   No Side Effects
Treatment Info
Condition / reason:   Eye allergies
Dosage & duration:   1 drop per eye (dosage frequency: 2 times a day) for the period of 15 days
Other conditions:   Seasonal allergies
Other drugs taken:   Reactine
Reported Results
Benefits:   I have seasonal allergies and especially in the spring and fall, my eyes itch and get dry. These drops contain anti-histamines that are delivered directly into the eye, and therefore are more effective than just using anti-histamine pills. I think they also helped with the eczema-like flaking on my eyelids but I cannot be sure because I was also using anti-histamine pills at the time.
Side effects:   I did not experience any side effects.
Comments:   These drops really helped with the symptoms but I did wish I could use it more often than just 2 times a day.

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Page last updated: 2013-02-10

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