Penicillin V (Penicillin V Potassium) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Although the incidence of reactions to oral penicillins has been reported with much less frequency than following parenteral therapy, it should be remembered that all degrees of hypersensitivity, including fatal anaphylaxis, have been reported with oral penicillin.

The most common reactions to oral penicillin are nausea, vomiting, epigastric distress, diarrhea, and black hairy tongue. The hypersensitivity reactions reported are skin eruptions (maculopapular to exfoliative dermatitis), urticaria and other serum-sickness like reactions, laryngeal edema, and anaphylaxis.

Fever and eosinophilia may frequently be the only reaction observed. Hemolytic anemia, leukopenia, thrombocytopenia, neuropathy, and nephropathy are infrequent reactions and usually associated with high doses of parenteral penicillin.

REPORTS OF SUSPECTED PENICILLIN V SIDE EFFECTS / ADVERSE REACTIONS

Possible Penicillin V side effects / adverse reactions in 34 year old male

Reported by a health professional (non-physician/pharmacist) from Denmark on 2011-10-05

Patient: 34 year old male

Reactions: Blindness Transient, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Suspect drug(s):
Naproxen

Allopurinol
    Dosage: 300 mg
    Indication: Gout
    Start date: 2011-05-31
    End date: 2011-06-23

Penicillin V
    Dosage: po
    Administration route: Oral
    Indication: Tonsillitis
    Start date: 2011-06-21
    End date: 2011-06-23

Other drugs received by patient: Sodium Chloride; Levothyroxine Sodium; Dexamethasone

Possible Penicillin V side effects / adverse reactions in 7 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-10-06

Patient: 7 year old female

Reactions: Lymphadenopathy, Body Temperature Increased, Pyrexia, Rash, Drug Rash With Eosinophilia and Systemic Symptoms, Generalised Oedema, Eosinophilia, Rash Pruritic, Face Oedema, Lymphocyte Morphology Abnormal, Rash Maculo-Papular, Leukocytosis

Adverse event resulted in: hospitalization

Suspect drug(s):
Penicillin V
    Administration route: Oral
    Indication: Pharyngitis

Penicillin V

Possible Penicillin V side effects / adverse reactions in 34 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-10-07

Patient: 34 year old male weighing 91.7 kg (201.7 pounds)

Reactions: LIP Swelling, Skin Exfoliation, Oedema Peripheral, Oedema Mouth, Blindness Transient, Skin Swelling, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Suspect drug(s):
Allopurinol
    Dosage: 300 mg, unk
    Administration route: Oral
    Indication: Gout
    Start date: 2011-05-31
    End date: 2011-06-23

Naproxen Sodium
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Penicillin V
    Dosage: unk
    Administration route: Oral
    Indication: Tonsillitis
    Start date: 2011-06-21
    End date: 2011-06-23

Other drugs received by patient: Levothyroxine Sodium; Dexamethasone