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Periostat (Doxycycline Hyclate) - Published Studies

 
 



Periostat Related Published Studies

Well-designed clinical trials related to Periostat (Doxycycline Hyclate)

Effect of doxycycline vs placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial. [2014]

The effect of prolonged systemic doxycycline therapy on serum tissue degrading proteinases in coronary bypass patients: a randomized, double-masked, placebo-controlled clinical trial. [2014]

Subantimicrobial-dose doxycycline treatment increases serum cholesterol efflux capacity from macrophages. [2013]

A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis. [2012]

Clinical studies on the management of periodontal diseases utilizing subantimicrobial dose doxycycline (SDD). [2011.02]

Comparative evaluation of the efficacy of 10% doxycycline hyclate in the periodontal treatment of smokers - a clinical and microbiological study. [2011]

Sub-antimicrobial doxycycline for periodontitis reduces hemoglobin A1c in subjects with type 2 diabetes: a pilot study. [2011]

Pulsed azithromycin treatment is as effective and safe as 2-week-longer daily doxycycline treatment of acne vulgaris: a randomized, double-blind, noninferiority study. [2011]

The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. [2011]

Comparison of therapeutic effects of oral doxycycline and azithromycin in patients with moderate acne vulgaris: What is the role of age? [2011]

Effective and safe combination therapy for severe acne vulgaris: a randomized, vehicle-controlled, double-blind study of adapalene 0.1%-benzoyl peroxide 2.5% fixed-dose combination gel with doxycycline hyclate 100 mg. [2010.02]

A single dose of doxycycline in combination with diethylcarbamazine for treatment of bancroftian filariasis. [2010]

Doxycycline vs. levofloxacin in the treatment of community-acquired pneumonia. [2010]

Oral steroids and doxycycline: two different approaches to treat nasal polyps. [2010]

Doxycycline 40 mg capsules (30 mg immediate-release/10 mg delayed-release beads): anti-inflammatory dose in rosacea. [2010]

Doxycycline effects on serum bone biomarkers in post-menopausal women. [2010]

Administration of doxycycline in drinking water for treatment of spiral bacterial infection in cockatiels. [2008.02.01]

Regeneration of degree ii furcation defects with a 4% doxycycline hyclate bioabsorbable barrier. [2008.01]

A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers. [2007.04]

Pharmacokinetic and bioequivalence study of meloxicam tablets in healthy male subjects. [2007]

The effect of topical doxycycline usage on gingival crevicular fluid MMP-8 levels of chronic and aggressive periodontitis patients: a pilot study. [2006.08]

A randomized, double-blind, placebo-controlled trial of the combined effect of doxycycline hyclate 20-mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea. [2005.11]

Effect of locally delivered doxycycline hyclate on human fibroblast attachment to subgingival calculus. [2005.02]

The treatment of acne vulgaris with low dosage doxycycline. [2005]

Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing. [2004.11]

Sustained release of doxycycline for the treatment of peri-implantitis: randomised controlled trial. [2004.10]

Initial antimicrobial effect of controlled-release doxycycline in subgingival sites. [2004.10]

Therapy with adjunctive doxycycline local delivery in patients with type 1 diabetes mellitus and periodontitis. [2004.08]

Comparative bioavailability study of doxycycline hyclate (equivalent to 100 mg doxycycline) capsules (doxycin vs vibramycin) for bioequivalence evaluation in healthy adult volunteers. [2004.07]

Comparison of the pharmacokinetic profiles of two locally administered doxycycline gels in crevicular fluid and saliva. [2004.04]

Effects of subantimicrobial-dose doxycycline in the treatment of moderate acne. [2003.04]

Tolerability of doxycycline monohydrate salt vs. chloroquine-proguanil in malaria chemoprophylaxis. [2002.11]

Utilisation of locally delivered doxycycline in non-surgical treatment of chronic periodontitis. A comparative multi-centre trial of 2 treatment approaches. [2001.08]

The effect of locally delivered controlled-release doxycycline or scaling and root planing on periodontal maintenance patients over 9 months. [2000.01]

Effects of smoking on local delivery of controlled-release doxycycline as compared to scaling and root planing. [1999.10]

Two multi-center studies evaluating locally delivered doxycycline hyclate, placebo control, oral hygiene, and scaling and root planing in the treatment of periodontitis. [1999.05]

Long-term sub-antimicrobial doxycycline (Periostat) as adjunctive management in adult periodontitis: effects on subgingival bacterial population dynamics. [1998.11]

The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum. [1998.10]

Doxycycline hyclate treatment of experimental canine ehrlichiosis followed by challenge inoculation with two Ehrlichia canis strains. [1998.02]

Multi-center comparative evaluation of subgingivally delivered sanguinarine and doxycycline in the treatment of periodontitis. II. Clinical results. [1997.02]

Randomized comparison of ofloxacin and doxycycline for chlamydia and ureaplasma urethritis and cervicitis. [1990]

Effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline. [1989.04]

Well-designed clinical trials possibly related to Periostat (Doxycycline Hyclate)

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases. [2015]

Effects of centrally acting angiotensin converting enzyme inhibitors on functional decline in patients with Alzheimer's disease. [2014]

The association between clinical and radiographic periodontitis measurements during periodontal maintenance. [2013]

Safety and efficacy of WC2031 versus vibramycin for the treatment of uncomplicated urogenital Chlamydia trachomatis infection: a randomized, double-blind, double-dummy, active-controlled, multicenter trial. [2012]

Short-term combination therapy and long-term relapse prevention in the treatment of severe acne vulgaris. [2012]

Serum bone biomarkers and oral/systemic bone loss in humans. [2011]

Antibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. [2010]

Systemic MMP inhibition for periodontal wound repair: results of a multi-centre randomized-controlled clinical trial. [2009.02]

Combining host modulation and topical antimicrobial therapy in the management of moderate to severe periodontitis: a randomized multicenter trial. [2008.01]

Reduction in antimicrobial substantivity of MTAD after initial sodium hypochlorite irrigation. [2006.10]

Clinical experience results with clindamycin 1% benzoyl peroxide 5% gel (Duac) as monotherapy and in combination. [2005.03]

Local antimicrobial therapy after initial periodontal treatment. [2002.06]

The effect of postsurgical antibiotics and a bioabsorbable membrane on regenerative healing in Class II furcation defects. [1999.08]

Clinical evaluation of the use of calcium sulfate in regenerative periodontal surgery for the treatment of Class III furcation involvement. [1999]

Other research related to Periostat (Doxycycline Hyclate)

The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers. [2014]

A 2-year randomised placebo-controlled trial of doxycycline for lymphangioleiomyomatosis. [2014]

Evaluation of single-dose azithromycin versus standard azithromycin/doxycycline treatment and clinical assessment of regression course in patients with adult inclusion conjunctivitis. [2013]

Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis. [2013]

Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass. [2013]

The effect of sub-antimicrobial dose-doxycycline periodontal therapy on serum inflammatory biomarker C-reactive protein levels in post-menopausal Women: A 2-year, double-blinded, randomized clinical trial. [2013]

Experimental determination of a subantimicrobial dosage of doxycycline hyclate for treatment of periodontitis in Beagles. [2013]

Randomized masked controlled clinical trial to compare 7-day and 14-day course length of doxycycline in the treatment of Mycoplasma felis infection in shelter cats. [2013]

A double-blind controlled field trial of doxycycline and albendazole in combination for the treatment of bancroftian filariasis in India. [2013]

Comparison of the efficacy of amoxicillin-clavulanic acid, cefovecin, and doxycycline in the treatment of upper respiratory tract disease in cats housed in an animal shelter. [2012]

Doxycycline in the treatment of bleeding with DMPA: a double-blinded randomized controlled trial. [2012]

Comparison of doxycycline-streptomycin, doxycycline-rifampin, and ofloxacin-rifampin in the treatment of brucellosis: a randomized clinical trial. [2012]

Effects of combination therapy with celecoxib and doxycycline on neointimal hyperplasia and inflammatory biomarkers in coronary artery disease patients treated with bare metal stents. [2012]

Matrix metalloproteinase activity in stifle synovial fluid of cranial cruciate ligament deficient dogs and effect of postoperative doxycycline treatment. [2012]

A randomized controlled trial of subantimicrobial-dose doxycycline to prevent unscheduled bleeding with continuous oral contraceptive pill use. [2012]

A randomized study comparing levofloxacin, omeprazole, nitazoxanide, and doxycycline versus triple therapy for the eradication of Helicobacter pylori. [2011]

Biowaiver monographs for immediate release solid oral dosage forms: Doxycycline hyclate. [2010.04]

Doxycycline-mediated inhibition of matrix metalloproteinases improves healing after rotator cuff repair. [2010.02]

Comparative evaluation of subgingivally delivered 10% doxycycline hyclate and xanthan-based chlorhexidine gels in the treatment of chronic periodontitis. [2008.11.01]

The use and safety of doxycycline hyclate and other second-generation tetracyclines. [2008.09]

Pharmacokinetics after administration of an injectable experimental long-acting parenteral formulation of doxycycline hyclate in goats. [2008.08]

Pharmacokinetic study of an injectable long-acting parenteral formulation of doxycycline hyclate in calves. [2008.06]

A doxycycline hyclate rodent bait formulation for prophylaxis and treatment of tick-transmitted Borrelia burgdorferi. [2008.05]

A sustained-release formulation of doxycycline hyclate (Atridox) prevents simultaneous infection of Anaplasma phagocytophilum and Borrelia burgdorferi transmitted by tick bite. [2008.04]

Pharmacokinetics of doxycycline and tissue concentrations of an experimental long-acting parenteral formulation of doxycycline in Wistar rats. [2008]

Antibacterial activity and drug release of chitosan sponge containing doxycycline hyclate. [2008]

Intra-articular administration of doxycycline in calves. [2007.12]

Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate. [2007.09]

The use of doxycycline in periodontology. Histologic in vivo study on mice affected by diabetes mellitus. [2006.01]

Assessment of salivary levels of the chosen exoglycosidases in patients with aggressive periodontitis after treatment with doxycycline. [2006]

Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis. [2004.07]

Assessment of plasma concentrations of doxycycline in budgerigars fed medicated seed or water. [2003.10.01]

Subantimicrobial dose doxycycline for acne and rosacea. [2003.07]

The effects of subgingival calculus on the clinical outcomes of locally-delivered controlled-release doxycycline compared to scaling and root planing. [2002.02]

The significance of prior mechanical therapy for changes of periodontal status achieved by local delivery of a doxycyclinehyclate containing gel. [2001.12]

The role of Periostat in the management of adult periodontitis: a critical assessment. [1999.07]

Evaluation of Periostat for patient management. [1999.05]

Locally delivered doxycycline hyclate: case selection, preparation, and application. [1999]

The use of locally delivered doxycycline in the treatment of periodontitis. Clinical results. [1998.11]

Periodontal pocket treatment in beagle dogs using subgingival doxycycline from a biodegradable system. I. Initial clinical responses. [1996.11]

Histologic changes of doxycycline pleurodesis in rabbits. Effect of concentration and pH. [1994.10]

Effect of doxycycline hyclate on corneal epithelial wound healing in the rabbit alkali-burn model. Preliminary observations. [1993.09]

Pharmacokinetics and bioavailability of doxycycline hyclate after oral administration in calves. [1993.03]

Comparative pharmacokinetics of doxycycline in cats and dogs. [1990.12]

Pharmacokinetics and metabolic inertness of doxycycline in young pigs. [1990.08]

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