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Pyrazinamide (Pyrazinamide) - Current Clinical Trials

 
 



Pyrazinamide Related Clinical Trials

Optimization of MDR-TB Treatment Regimen Based on the Molecular Drug Susceptibility Results of Pyrazinamide [Recruiting]

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) [Active, not recruiting]

A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults [Completed]

Shortening Treatment by Advancing Novel Drugs [Recruiting]

A Phase 2 Open Label Partially Randomized Trial to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. [Recruiting]

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) [Completed]

Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis [Active, not recruiting]

Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis [Completed]

Early Bactericidal Activity Study of Faropenem(With Amoxicillin/Clavulanic Acid)in Patients With Pulmonary Tuberculosis [Recruiting]

Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat Tuberculosis [Completed]

Rapid Detection of Rifampin and Isoniazid Resistance by PCR Before Tuberculosis (TB) Treatment Initiation [Recruiting]

Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection [Completed]

Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection [Completed]

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) [Active, not recruiting]

Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis [Completed]

Early Bactericidal Activity (EBA) Study of Tuberculosis Regimens With and Without INH and Moxifloxacin [Recruiting]

Research on New Regimens for Retreatment Pulmonary Tuberculosis [Recruiting]

Assessing PA-824 for Tuberculosis (the APT Trial) [Recruiting]

Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB [Active, not recruiting]

Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design [Active, not recruiting]

Tuberculosis Treatment Shortening Trial [Completed]

PK Study of Anti-TB Drugs [Not yet recruiting]

TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment [Completed]

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB [Not yet recruiting]

An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis [Not yet recruiting]

Latency in Pulmonary Tuberculosis [Recruiting]

Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity [Completed]

Reintroduction Regimens After Hepatitis During Anti-tuberculosis Treatment [Recruiting]

Systematic Empirical vs. Test-guided Anti-TB Treatment Impact in Severely Immunosuppressed HIV-infected Adults Initiating ART With CD4 Cell Counts <100/mm3 [Recruiting]

Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis [Completed]

The Treatment of Tuberculosis in HIV-Infected Patients [Completed]

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients. [Completed]

Clinical Trial to Investigate the Pharmacokinetics of Second-Line Anti-Tuberculosis Agents [Completed]

Evaluation of the Pharmacokinetics of Antituberculosis Drugs and Tuberculosis Treatment Outcomes [Recruiting]

Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosis [Active, not recruiting]

REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment [Active, not recruiting]

TBTC Study 24: Intermittent Treatment of TB With Isoniazid Resistance or Intolerance [Completed]

Anti-tuberculosis (TB) Drug Levels and Hepatotoxicity [Completed]

TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment [Completed]

Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage [Completed]

A Randomized Trial of Three Regimens to Prevent Tuberculosis in HIV-Infected Patients With Anergy [Completed]

TBTC Study 27/28 PK: Moxifloxacin Pharmacokinetics During TB Treatment [Completed]

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis [Completed]

Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers [Completed]

Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis [Recruiting]

Patients Response to Early Switch To Oral:Osteomyelitis Study [Not yet recruiting]

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in HIV [Recruiting]

A Randomized Trial of DOTS Versus Enhanced DOTS for Community Control of Tuberculosis [Completed]

Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis [Completed]

TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening Regimens [Not yet recruiting]

Evaluation of Three Regimens of Chemoprophylaxis for Tuberculosis in Patients co-Infected by HIV and Mycobacterium Tuberculosis [Completed]

TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment [Completed]

Pharmacokinetics of Anti-TB Drugs in HIV/TB Co-infected Children in Ghana [Recruiting]

Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study) [Recruiting]

The Safety of Tuberculosis Treatments by Oral Inhalation [Not yet recruiting]

Effectiveness of a Simplified Short Regimen for Multidrug Resistant Tuberculosis in Uzbekistan [Active, not recruiting]

Improving Retreatment Success (IMPRESS) [Recruiting]

HRZE Fasted/Fed in Newly Diagnosed TB [Completed]

High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study [Recruiting]

Efficacy and Safety of Modified Anti-tubercular Regimens in Treatment of Tuberculosis in Patients With Underlying Compensated and Decompensated Chronic Liver Disease [Recruiting]

Directly Observed Therapy Short Course-Plus Versus DOTS for Retreatment of Relapsed Pulmonary Tuberculosis in Guangzhou [Recruiting]

Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs [Completed]

Study of Daily Rifapentine for Pulmonary Tuberculosis [Completed]

Efficacy of HUEXC030 in Subjects With Pulmonary Tuberculosis [Recruiting]

Linezolid Instead of Ethambutol in Treatment of Drug-susceptible Tuberculosis [Recruiting]

Effect of Prophylactic Use of Silymarin on Hepatotoxicity Induced by Anti-tuberculosis Drugs [Recruiting]

Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity [Completed]

Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients [Recruiting]

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection [Not yet recruiting]

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy [Recruiting]

Adverse Reactions and Efficacy of Fixed-dose Combination Anti-tuberculosis (TB) Drugs [Completed]

Efficacy and Safety of Qinbudan as an Adjunct Therapy for Retreatment Pulmonary Tuberculosis [Completed]

Randomized Clinical Trial Comparing 4RIF vs. 9INH for LTBI Treatment-effectiveness [Active, not recruiting]

Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study [Completed]

Optimization of the TB Treatment Regimen Cascade [Recruiting]

Phase 2a EBA Trial of AZD5847 [Completed]

A Study Of PNU-100480 In Newly Diagnosed, Treatment Sensitive Patients With Pulmonary Tuberculosis To Assess Early Bactericidal Activity (EBA) And Whole Blood Activity (WBA) [Completed]

An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB) [Recruiting]

Safety and Efficacy of Oral Immunomodulator in Tuberculosis (TB) and TB/HIV Patients [Completed]

Trial of High-Dose Rifampin in Patients With TB [Active, not recruiting]

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