DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Tirosint (Levothyroxine Sodium) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Common adverse reactions with levothyroxine therapy are primarily those of hyperthyroidism due to therapeutic overdosage [See Overdosage]. They include the following:

  • General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating
  • Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia
  • Musculoskeletal: tremors, muscle weakness
  • Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest
  • Respiratory: dyspnea
  • Gastrointestinal (GI): diarrhea, vomiting, abdominal cramps, elevations in liver function tests
  • Dermatologic: hair loss, flushing
  • Endocrine: decreased bone mineral density
  • Reproductive: menstrual irregularities, impaired fertility

Adverse Reactions in Children

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height. Seizures have been reported rarely with the institution of levothyroxine therapy.

Hypersensitivity Reactions

Hypersensitivity reactions to inactive ingredients (in this product or other levothyroxine products) have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.



REPORTS OF SUSPECTED TIROSINT SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Tirosint. The information is not vetted and should not be considered as verified clinical evidence.

Possible Tirosint side effects / adverse reactions in 48 year old female

Reported by a physician from United States on 2011-10-03

Patient: 48 year old female

Reactions: Ventricular Extrasystoles, Drug Intolerance, Hyperhidrosis, Tremor, Hot Flush, Sleep Disorder, Alopecia, Insomnia, Feeling Abnormal

Suspect drug(s):
Synthroid
    Dosage: 50mcg daily
    Indication: Hypothyroidism
    Start date: 2009-01-01
    End date: 2011-08-10

Tirosint
    Dosage: one capsule daily, oral
    Administration route: Oral
    Indication: Goitre
    Start date: 2011-08-11
    End date: 2011-08-22

Tirosint
    Dosage: one capsule daily, oral
    Administration route: Oral
    Indication: Hypothyroidism
    Start date: 2011-08-11
    End date: 2011-08-22



Possible Tirosint side effects / adverse reactions in 70 year old female

Reported by a consumer/non-health professional from United States on 2011-12-21

Patient: 70 year old female weighing 74.8 kg (164.7 pounds)

Reactions: Hallucination, Visual, Vision Blurred, Dizziness, Asthenia, Derealisation

Suspect drug(s):
Tirosint



Possible Tirosint side effects / adverse reactions in 49 year old female

Reported by a consumer/non-health professional from United States on 2012-03-29

Patient: 49 year old female

Reactions: Dyspnoea, Oedema Peripheral, Dehydration, Heart Rate Increased, Hypotension, Drug Interaction, Blood Thyroid Stimulating Hormone Decreased

Suspect drug(s):
Tirosint

Tirosint
    Dosage: 112 mcg for 5 days weekly/125 mcg for 2 days weekly, oral
    Administration route: Oral
    Indication: Basedow's Disease

Tirosint
    Dosage: 112 mcg for 5 days weekly/125 mcg for 2 days weekly, oral
    Administration route: Oral
    Indication: Radioactive Iodine Therapy



See index of all Tirosint side effect reports >>

Drug label data at the top of this Page last updated: 2013-01-09

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017