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Toprol-XL (Metoprolol Succinate) - Published Studies

 
 



Toprol-XL Related Published Studies

Well-designed clinical trials related to Toprol-XL (Metoprolol)

Effect of fixed dose combinations of metoprolol and amlodipine in essential hypertension: MARS ? A randomized controlled trial. [2011.12]

Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure-a randomized study. [2011.10.15]

beta-Blockers in patients with intermittent claudication and arterial hypertension: results from the nebivolol or metoprolol in arterial occlusive disease trial. [2011.08]

Differential effects of nebivolol and metoprolol on central aortic pressure and left ventricular wall thickness. [2011.06]

The effect of nebivolol versus metoprolol succinate extended release on asymmetric dimethylarginine in hypertension. [2011.05]

Long-term treatment with low-dose metoprolol CR/XL is associated with increased plaque echogenicity: the Beta-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS). [2011.04]

Reversal of subclinical left ventricular dysfunction by antihypertensive treatment: a prospective trial of nebivolol against metoprolol. [2011.04]

Influence of metoprolol dosage release formulation on the pharmacokinetic drug interaction with paroxetine. [2011.03]

Effect of atenolol vs metoprolol succinate on vascular function in patients with hypertension. [2011.01]

Metoprolol versus amiodarone in the prevention of atrial fibrillation after cardiac surgery: a randomized trial. [2010.12.07]

Cardioprotective effect of metoprolol and enalapril in doxorubicin-treated lymphoma patients: a prospective, parallel-group, randomized, controlled study with 36-month follow-up. [2010.11]

[Effect between felodipine plus irbesartan and felodipine plus metoprolol regimen on the sexual function in young and middle-aged women with hypertension]. [2010.08]

[Effects of carvedilol and metoprolol on expression of autoantibodies against cardiac adrenergic receptors in aged patients with chronic heart failure and ventricular arrhythmia]. [2010.07]

Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study. [2010.05.25]

Toward optimal treatment in women: the effect of sex on metoprolol-diphenhydramine interaction. [2010.02]

Comparison of Candesartan versus Metoprolol for treatment of systemic hypertension after repaired aortic coarctation. [2010.01.15]

Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine. [2010]

Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings. [2009.12]

Effect of metoprolol on quality of life in the prevention of syncope trial. [2009.10]

Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. [2009.08]

Antihypertensive efficacy of metoprolol XL/low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in indian patients with mild-to-moderate essential hypertension. [2009.07.22]

Prevention of perioperative atrial fibrillation with betablockers in coronary surgery: betaxolol versus metoprolol. [2009.07]

[Therapeutic effects of amiodarone and metoprolol on chronic heart failure complicated by ventricular arrhythmia] [2009.06]

The influence of renal function on clinical outcome and response to beta-blockade in systolic heart failure: insights from Metoprolol CR/XL Randomized Intervention Trial in Chronic HF (MERIT-HF). [2009.05]

Influence of metoprolol on systolic and diastolic function in children with heart failure. [2009.03.01]

Comparison of carvedilol and metoprolol on serum lipid concentration in diabetic hypertensive patients. [2009.03]

The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment. [2009.02.20]

Erectile dysfunction after therapy with metoprolol: the hawthorne effect. [2009]

[Comparison of metoprolol vs clonazepam as a first treatment choice among patients with neurocardiogenic syncope] [2008.11]

Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) study. [2008.09]

A randomized, double-blind study of valsartan versus metoprolol on arterial distensibility and endothelial function in essential hypertension. [2008.07]

[Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery] [2008.06.03]

Randomized comparison of metoprolol versus conventional treatment in preventing recurrence of vasovagal syncope in children and adolescents. [2008.04]

Comparison of the effects of carvedilol and metoprolol on exercise ventilatory efficiency in patients with congestive heart failure. [2008.03]

Renal and cardiac effects of antihypertensive treatment with ramipril vs metoprolol in autosomal dominant polycystic kidney disease. [2008.02]

Nebivolol and metoprolol for treating migraine: an advance on beta-blocker treatment? [2008.01]

[Controlled release metoprolol succinate in MERIT-HF. Analysis of patients subgroups] [2008]

Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement. [2008]

Effect of nebivolol and metoprolol treatments on serum asymmetric dimethylarginine levels in hypertensive patients with type 2 diabetes mellitus. [2007.12]

Effect of carvedilol and metoprolol on the mode of death in patients with heart failure. [2007.11]

Effect of beta-blocker therapy on left atrial function in patients with heart failure: comparison of metoprolol succinate with carvedilol. [2007.10]

Optimal beta-blocker for prevention of atrial fibrillation after on-pump coronary artery bypass graft surgery: carvedilol versus metoprolol. [2007.09]

Central mechanisms of controlled-release metoprolol in migraine: a double-blind, placebo-controlled study. [2007.09]

Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET). [2007.08]

Prognostic importance of plasma NT-pro BNP in chronic heart failure in patients treated with a beta-blocker: results from the Carvedilol Or Metoprolol European Trial (COMET) trial. [2007.08]

Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial. [2007.07.03]

Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction. [2007.07]

Effects of carvedilol versus metoprolol on endothelial function and oxidative stress in patients with type 2 diabetes mellitus. [2007.07]

Pronounced improvement in systolic and diastolic ventricular long axis function after treatment with metoprolol. [2007.06]

Maintenance of sinus rhythm with metoprolol CR initiated before cardioversion and repeated cardioversion of atrial fibrillation: a randomized double-blind placebo-controlled study. [2007.06]

Effects of nebivolol on platelet activation in hypertensive patients: a comparative study with metoprolol. [2007.03.20]

Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. [2007.03.06]

Effect of diltiazem and metoprolol on left atrial appendix functions in patients with nonvalvular chronic atrial fibrillation. [2007.03]

Efficacy and safety of extended release metoprolol succinate in hypertensive children 6 to 16 years of age: a clinical trial experience. [2007.02]

Acute hemodynamic effects of moderate doses of nebivolol versus metoprolol in patients with systolic heart failure. [2007.02]

Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial. [2007]

Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial. [2007]

Comparative bioavailability of metoprolol tartrate after oral and transdermal administration in healthy male volunteers. [2007]

The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial. [2006.11]

Effectiveness and tolerability of acupuncture compared with metoprolol in migraine prophylaxis. [2006.11]

Randomized, double-blind comparison of acute beta1-blockade with 50 mg metoprolol tartrate vs 25 mg carvedilol in normal subjects. [2006.09]

Valdecoxib does not interfere with the CYP2D6 substrate metoprolol. [2006.09]

Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) trial: a randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery. [2006.08]

Intravenous administration of metoprolol is more effective than oral administration in the prevention of atrial fibrillation after cardiac surgery. [2006.07.04]

Carvedilol versus Metoprolol for the prevention of atrial fibrillation after off-pump coronary bypass surgery: rationale and design of the Carvedilol or Metoprolol Post-Revascularization Atrial Fibrillation Controlled Trial (COMPACT). [2006.06]

A comparison of the effects of carvedilol and metoprolol on well-being, morbidity, and mortality (the "patient journey") in patients with heart failure: a report from the Carvedilol Or Metoprolol European Trial (COMET). [2006.04.18]

A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT). [2006.04]

[Influences of perioperative metoprolol on hemodynamics and myocardial ischaemia in elderly patients undergoing noncardiac surgery] [2006.04]

Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure. [2006.04]

Modulated release metoprolol succinate formulation based on ionic interactions: in vivo proof of concept. [2006.03.10]

Prevention of Syncope Trial (POST): a randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope. [2006.03.07]

Effects of metoprolol therapy on cardiac troponin-I levels after elective percutaneous coronary interventions. [2006.03]

Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients. [2006.03]

Introduction of metoprolol increases plasma B-type cardiac natriuretic peptides in mild, stable heart failure. [2006.02.21]

After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. [2006.02]

Comparison of carvedilol and metoprolol in patients with acute myocardial infarction undergoing primary coronary intervention--the PASSAT Study. [2006.01]

The use of metoprolol CR/XL in the treatment of patients with diabetes and chronic heart failure. [2006]

Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. [2005.11.05]

Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial. [2005.11]

Carvedilol exerts more potent antiadrenergic effect than metoprolol in heart failure. [2005.10]

Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction. [2005.10]

Carvedilol improves myocardial contractility compared with metoprolol in patients with chronic hibernating myocardium after revascularization. [2005.09]

Metoprolol prevents sodium retention induced by lower body negative pressure in healthy men. [2005.08]

Comparison of the effectiveness of intravenous diltiazem and metoprolol in the management of rapid ventricular rate in atrial fibrillation. [2005.06]

Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women. [2005.06]

[Metoprolol and atenolol in mild-to-moderate chronic heart failure: comparative study] [2005.05]

The rationale and design of the Glycemic Effects in Diabetes Mellitus Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) trial. [2005.03]

Association between adherence measurements of metoprolol and health care utilization in older patients with heart failure. [2005.03]

Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. [2005.02]

What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF). [2005.01.18]

Efficacy, safety and tolerability of metoprolol CR/XL in patients with diabetes and chronic heart failure: experiences from MERIT-HF. [2005.01]

Carvedilol versus metoprolol in the acute phase of myocardial infarction:. [2005.01]

Pharmacokinetic drug interactions of gefitinib with rifampicin, itraconazole and metoprolol. [2005]

Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis. [2004.12]

Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial. [2004.11.10]

Efficacy, safety and tolerability of beta-adrenergic blockade with metoprolol CR/XL in elderly patients with heart failure. [2004.08]

Comprehensive adrenergic receptor blockade with carvedilol is superior to beta-1-selective blockade with metoprolol in patients with heart failure: COMET. [2004.07]

Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo. [2004.06.29]

Effects of moxonidine vs. metoprolol on blood pressure and metabolic control in hypertensive subjects with type 2 diabetes. [2004.06]

Effects of metoprolol on QT interval and QT dispersion in Type 1 diabetic patients with abnormal albuminuria. [2004.06]

Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery? [2004.05]

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