TRIAZ SUMMARY
TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Gels, TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Cleansers and TRIAZ® (benzoyl peroxide) 3%, 6%, and 9% Pads are topical, gel-based, benzoyl peroxide containing preparations for use in the treatment of acne vulgaris. Benzoyl peroxide is an oxidizing agent that possesses antibacterial properties and is classified as a keratolytic.
TRIAZ 3%, 6%, and 9% Gels, TRIAZ 3%, 6%, and 9% Cleansers and TRIAZ 3%, 6%, and 9% Pads are indicated for the topical treatment of acne vulgaris.
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NEWS HIGHLIGHTSMedia Articles Related to Triaz (Benzoyl Peroxide)
Health Tip: Four Common Types Of Acne
Source: MedicineNet Acne Specialty [2017.09.20]
Title: Health Tip: Four Common Types Of Acne
Category: Health News
Created: 9/20/2017 12:00:00 AM
Last Editorial Review: 9/20/2017 12:00:00 AM
Acne (Pimples) Quiz: Test Your Medical IQ
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Acne (Pimples) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/28/2011 4:15:00 PM
Last Editorial Review: 9/19/2017 5:39:39 PM
Skin Quiz: Acne, Dry Skin, Dandruff & More
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Skin Quiz: Acne, Dry Skin, Dandruff & More
Category: MedicineNet Quiz
Created: 10/7/2010 12:00:00 AM
Last Editorial Review: 9/19/2017 5:01:04 PM
Health Tip: Can't Clear Your Acne?
Source: MedicineNet Acne Specialty [2017.08.02]
Title: Health Tip: Can't Clear Your Acne?
Category: Health News
Created: 8/2/2017 12:00:00 AM
Last Editorial Review: 8/2/2017 12:00:00 AM
Acne 101: Types, Best Treatments, Medication, Cystic Acne
Source: MedicineNet isotretinoin Specialty [2017.05.04]
Title: Acne 101: Types, Best Treatments, Medication, Cystic Acne
Category: Slideshows
Created: 10/16/2014 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM
Published Studies Related to Triaz (Benzoyl Peroxide)
The efficacy, safety, and tolerability of adapalene versus benzoyl peroxide in
the treatment of mild acne vulgaris: a randomized trial. [2013]
Topical treatments, such as adapalene and benzoyl peroxide (BPO), are popular in
mild-to-moderate acne vulgaris... Both topical adapalene 0.1% and BPO 2.5% gels seem
safe and effective in mild acne vulgaris, with a marginal tendency toward the
former.
Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel:
efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be
Treatment of moderate to severe acne vulgaris in a Hispanic population: a
post-hoc analysis of efficacy and tolerability of clindamycin phosphate
1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate
Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.
Combination therapy with adapalene-benzoyl peroxide and oral lymecycline in the treatment of moderate to severe acne vulgaris: a multicentre, randomized, double-blind controlled study. [2011.08]
BACKGROUND: Oral antibiotics in association with a topical retinoid with or without benzoyl peroxide (BPO) are the recommended first-line option in the treatment of moderate to severe acne vulgaris. OBJECTIVES: To evaluate the efficacy and safety of oral lymecycline 300 mg with adapalene 0.1%-BPO 2.5% (A/BPO) fixed-dose gel in comparison with oral lymecycline 300 mg with a vehicle gel in subjects with moderate to severe acne vulgaris... CONCLUSION: These results demonstrate the clinical benefit of combining A/BPO with lymecycline in the treatment of moderate to severe acne vulgaris. (c) 2011 The Authors. BJD (c) 2011 British Association of Dermatologists 2011.
Clinical Trials Related to Triaz (Benzoyl Peroxide)
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications [Completed]
This is a single-blind (blinded expert grader), randomized, half-face study being conducted
at one clinical site. On 1 side of the face, the subject will apply 1 of the 2 test
products, antibiotic and benzoyl peroxide or benzoyl peroxide and adapalene gel and the
contra lateral side of the face will remain non-treated to serve as a control. Approximately
25-30 male and female healthy subjects will be randomly assigned to each product
Study Comparing Adapalene and Benzoyl Peroxide Gel 0.1%/2.5% to Epiduo� and Both to a Placebo Control in the Treatment of Acne Vulgaris [Completed]
A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac� Topical Gel in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the relative efficacy and safety of the test
formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to
the marketed formulation Duac® Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in
the treatment of the inflamed lesions of acne vulgaris. Both the test and reference
formulations will also be compared to a placebo formulation to test for superiority.
Efficacy and Tolerance of a Derivative of Salicylic Acid and 5% Benzoyl Peroxide in Facial Acne Vulgaris [Completed]
Acne vulgaris is a frequent inflammatory skin condition involving the pilosebaceous unit and
affecting more than 80% of teenagers. Mild to moderate acne vulgaris is usually treated with
topical agents such as benzoyl peroxide, retinoids and antibiotics. These treatments can be
associated with local tolerance problems and/or antibiotic resistance. Salicylic acid has
been shown to be an effective treatment for acne. LHA is a lipophilic hydroxy acid
derivative of salicylic acid that has comedolytic and antibacterial properties.
The objective of this trial was to compare the efficacy and tolerance of a cream formulation
containing 0. 3% LHA (LHA formulation) to a 5% benzoyl peroxide gel.
Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the safety and efficacy profiles of Taro
Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1. 2%/2. 5% to Acanya®
(Clindamycin Phosphate and Benzoyl Peroxide) Gel, 1. 2%/2. 5% and to demonstrate the superior
efficacy of the two active formulations over that of the vehicle in the treatment of acne
vulgaris.
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 4 ratings/reviews, Triaz has an overall score of 8.25. The effectiveness score is 8.50 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Triaz review by 27 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | Acne |
| Dosage & duration: | | apply every night for 6 months (dosage frequency: apply every night for 6 months) for the period of 6 months |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | My spots were reduced dramacially, skin cleared up and felt better. my confidence improved. i would recommend this product to other people. |
| Side effects: | | very slight dry skin in the areas I used the gel the most. |
| Comments: | | I had to apply gel each night and keep it on whilst asleep, I would wash off in the morning and use other products as normal. |
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| | Triaz review by 28 year old male patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | 10% (dosage frequency: daily) for the period of on and off 7 yrs |
| Other conditions: | | dry skin |
| Other drugs taken: | | nothing | | |
Reported Results |
| Benefits: | | The acne cleared up for a while but soon after discontinuing use it would return. It reduced breakouts significantly. |
| Side effects: | | Dry irritated skin and burning. Over many years loss of elasticity and slight damage to the skin. |
| Comments: | | The treatment was to cover entire affected area twice daily until acne cleared up. Was not supposed to use any other topical treatments with the cream. |
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| | Triaz review by 28 year old male patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | 10% (dosage frequency: daily) for the period of on and off 7 yrs |
| Other conditions: | | dry skin |
| Other drugs taken: | | nothing | | |
Reported Results |
| Benefits: | | The acne cleared up for a while but soon after discontinuing use it would return. It reduced breakouts significantly. |
| Side effects: | | Dry irritated skin and burning. Over many years loss of elasticity and slight damage to the skin. |
| Comments: | | The treatment was to cover entire affected area twice daily until acne cleared up. Was not supposed to use any other topical treatments with the cream. |
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Page last updated: 2017-09-20
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