Zomig Nasal (Zolmitriptan Nasal) - Summary

ZOMIG NASAL SUMMARY

ZOMIG^® (zolmitriptan) Nasal Spray contains zolmitriptan, which is a selective 5-hydroxytryptamine_1B/1D(5-HT_1B/1D) receptor agonist.

ZOMIG Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults.

ZOMIG is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine (see CONTRAINDICATIONS). Safety and effectiveness of ZOMIG have not been established for cluster headache, which is present in an older, predominantly male population.

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NEWS HIGHLIGHTS

Media Articles Related to Zomig Nasal (Zolmitriptan)

Pictures of Famous People Coping With Migraines
Source: MedicineNet Headache Specialty [2017.09.08]
Title: Pictures of Famous People Coping With Migraines
Category: Slideshows
Created: 11/5/2012 12:00:00 AM
Last Editorial Review: 9/8/2017 12:00:00 AM

Many Migraine Sufferers Given Unecessary Opioids, Study Finds
Source: MedicineNet Headache Specialty [2017.08.28]
Title: Many Migraine Sufferers Given Unecessary Opioids, Study Finds
Category: Health News
Created: 8/25/2017 12:00:00 AM
Last Editorial Review: 8/28/2017 12:00:00 AM

Migraine vs. Headache: Differences and Similarities
Source: MedicineNet Analgesics, Antipyretics Specialty [2017.06.26]
Title: Migraine vs. Headache: Differences and Similarities
Category: Diseases and Conditions
Created: 6/21/2017 12:00:00 AM
Last Editorial Review: 6/26/2017 12:00:00 AM

Migraine
Source: MedicineNet amitriptyline Specialty [2017.05.22]
Title: Migraine
Category: Symptoms and Signs
Created: 2/27/2015 12:00:00 AM
Last Editorial Review: 5/22/2017 12:00:00 AM

Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2017.03.13]
Title: Migraine Headache
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/13/2017 12:00:00 AM

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Published Studies Related to Zomig Nasal (Zolmitriptan)

Efficacy of frovatriptan in the acute treatment of menstrually related migraine: analysis of a double-blind, randomized, multicenter, Italian, comparative study versus zolmitriptan. [2011.05]
Menstrually related migraine (MRM) is a particularly difficult-to-treat pain condition, associated with substantial disability. Aim of this study was to compare the efficacy and safety of frovatriptan and zolmitriptan in the treatment of MRM attacks, analyzing data from a multicenter, randomized, double blind, cross-over study...

Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan. [2011.02]
BACKGROUND: Endpoints used to evaluate the efficacy of acute anti-migraine drugs do not measure the tolerability. Sustained pain-free response with no adverse events has been recommended as a composite endpoint which measures the efficacy and tolerability attributes that patients desire... CONCLUSION: Composite efficacy-plus-tolerability endpoints may be useful for facilitating comparisons between treatments.

Efficacy of frovatriptan in the acute treatment of menstrually related migraine: analysis of a double-blind, randomized, multicenter, Italian, comparative study versus zolmitriptan. [2011]
Menstrually related migraine (MRM) is a particularly difficult-to-treat pain condition, associated with substantial disability. Aim of this study was to compare the efficacy and safety of frovatriptan and zolmitriptan in the treatment of MRM attacks, analyzing data from a multicenter, randomized, double blind, cross-over study...

Frovatriptan versus zolmitriptan for the acute treatment of migraine: a double-blind, randomized, multicenter, Italian study. [2010.06]
The objective of this study is to assess patients' satisfaction with migraine treatment with frovatriptan (F) or zolmitriptan (Z), by preference questionnaire. 133 subjects with a history of migraine with or without aura (IHS criteria) were randomized to F 2.5 mg or Z 2.5 mg... In conclusion, our study suggests that F has a similar efficacy of Z, with some advantage as regards tolerability and recurrence.

Frovatriptan versus zolmitriptan for the acute treatment of migraine: a double-blind, randomized, multicenter, Italian study. [2010]
The objective of this study is to assess patients' satisfaction with migraine treatment with frovatriptan (F) or zolmitriptan (Z), by preference questionnaire. 133 subjects with a history of migraine with or without aura (IHS criteria) were randomized to F 2.5 mg or Z 2.5 mg... In conclusion, our study suggests that F has a similar efficacy of Z, with some advantage as regards tolerability and recurrence.

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Clinical Trials Related to Zomig Nasal (Zolmitriptan)

Determine Central 5-HT1B Receptor Occupancy of ZOMIG� Rapimelt (Zolmitriptan) in Healthy Male Volunteers [Completed]

Zomig - Treatment of Acute Migraine Headache in Adolescents [Completed]
The purpose of this study is to investigate if Zomig® Nasal Spray will help children (age 12-17 years) with migraine headaches feel better. This will be done by comparing 3 different doses of Zomig Nasal Spray with placebo nasal spray (inactive treatment).

Efficacy of Zolmitriptan (Zomig) in the Treatment of Migraines in Adolescents [Completed]
The purpose of this study is to evaluate the effectiveness and safety of Zolmitriptan (Zomig) nasal spray, 5. 0 mg, compared with placebo (inactive drug) for 2 migraine headaches over a 3-month period in adolescent patients (aged 12 to 17 years) with migraine headaches

Efficacy and Tolerability of Zolmitriptan Nasal Spray [Completed]
The purpose of this study is to evaluate the effectiveness and tolerability (the ability not to experience ill effects from the study drug) of a zolmitriptan nasal spray, 5. 0 mg, compared with placebo (inactive drug) for 2 migraine headaches for up to 12 weeks in adult subjects with migraine headaches

Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine [Completed]
The purpose of this study is to Compare the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet in the acute treatment of migraine. To develop and evaluate a set of importance weights for a predefined set of treatment attributes for migraine suffers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet. To contrast the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet at early time points. To analyze the patterns of self-reported tolerability of migraine sufferers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet.

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