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Zyloprim (Allopurinol) - Published Studies

 
 



Zyloprim Related Published Studies

Well-designed clinical trials related to Zyloprim (Allopurinol)

In a double-blind, randomized and placebo-controlled trial, adjuvant allopurinol improved symptoms of mania in in-patients suffering from bipolar disorder. [2014]

Allopurinol for mania: a randomized trial of allopurinol versus placebo as add-on treatment to mood stabilizers and/or antipsychotic agents in manic patients with bipolar disorder. [2014]

Allopurinol reduces left ventricular mass in patients with type 2 diabetes and left ventricular hypertrophy. [2013]

High-dose allopurinol reduces left ventricular mass in patients with ischemic heart disease. [2013]

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris. [2011.08.16]

Allopurinol benefits left ventricular mass and endothelial dysfunction in chronic kidney disease. [2011.07]

Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study. [2011.07]

Effect of long-term and high-dose allopurinol therapy on endothelial function in normotensive diabetic patients. [2011.06]

Effect of allopurinol on blood pressure and aortic compliance in hypertensive patients. [2011.04]

Effects of rosuvastatin and allopurinol on circulating endothelial progenitor cells in patients with congestive heart failure: the impact of inflammatory process and oxidative stress. [2011.01]

Does allopurinol prevent post endoscopic retrograde cholangio- pancreatography pancreatitis? A randomized double blind trial. [2011]

An allopurinol-controlled, multicenter, randomized, open-label, parallel between-group, comparative study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with hyperuricemia including those with gout in Japan: phase 2 exploratory clinical study. [2011]

An allopurinol-controlled, randomized, double-dummy, double-blind, parallel between-group, comparative study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with hyperuricemia including those with gout in Japan: phase 3 clinical study. [2011]

Comparative effects of rosuvastatin and allopurinol on circulating levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with chronic heart failure. [2010.12.03]

Uric acid level and allopurinol use as risk markers of mortality and morbidity in systolic heart failure. [2010.11]

Elevated levels of asymmetric dimethylarginine in chronic heart failure: a pathophysiologic link between oxygen radical load and impaired vasodilator capacity and the therapeutic effect of allopurinol. [2010.10]

Control of plasma uric acid in adults at risk for tumor Lysis syndrome: efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone--results of a multicenter phase III study. [2010.09.20]

Effect of allopurinol in chronic kidney disease progression and cardiovascular risk. [2010.08]

Effect of preoperative administration of allopurinol in patients undergoing surgery for valvular heart diseases. [2010.07]

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial. [2010.06.19]

Allopurinol mouth rinse for prophylaxis of fluorouracil-induced mucositis. [2010.05]

Effect of allopurinol in decreasing proteinuria in type 2 diabetic patients. [2010.04]

Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study. [2010.02.18]

[Rasburicase versus allopurinol in the treatment of hyperuricaemia in tumour lysis syndrome] [2010.02]

The alkalizer citrate reduces serum uric Acid levels and improves renal function in hyperuricemic patients treated with the xanthine oxidase inhibitor allopurinol. [2010]

Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study. [2010]

Allopurinol mouth rinse for prophylaxis of fluorouracil-induced mucositis. [2010]

The effect of allopurinol on the cerebral vasculature of patients with subcortical stroke; a randomized trial. [2009.11]

Multicentric, controlled clinical study to evaluate effectiveness and safety of miltefosine and allopurinol for canine leishmaniosis. [2009.10]

Allopurinol mouth rinse for prophylaxis of fluorouracil-induced mucositis. [2009.07.29]

Maternal allopurinol during fetal hypoxia lowers cord blood levels of the brain injury marker S-100B. [2009.07]

A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout. [2009.06]

Oral allopurinol to prevent hyperamylasemia and acute pancreatitis after endoscopic retrograde cholangiopancreatography. [2009.04.07]

A double-blind trial of adjunctive allopurinol for schizophrenia. [2009.04]

Effects of benzbromarone and allopurinol on adiponectin in vivo and in vitro. [2009.04]

Allopurinol and nitric oxide activity in the cerebral circulation of those with diabetes: a randomized trial. [2009.01]

Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. [2009.01]

Effects of allopurinol and vitamin E on renal function in patients with cardiac coronary artery bypass grafts. [2009]

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial. [2008.12]

Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. [2008.11.15]

Allopurinol Use Yields Potentially Beneficial Effects on Inflammatory Indices in Those With Recent Ischemic Stroke. A Randomized, Double-Blind, Placebo-Controlled Trial. [2008.10.09]

Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. [2008.08.27]

A double-blind, randomized, placebo-controlled 4-week study on the efficacy and safety of the purinergic agents allopurinol and dipyridamole adjunctive to lithium in acute bipolar mania. [2008.08]

A Double-Blind, Randomized, Placebo-Controlled 4-Week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole Adjunctive to Lithium in Acute Bipolar Mania. [2008.07.29]

Allopurinol to prevent pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized placebo-controlled trial. [2008.04]

Allopurinol treatment reduces arterial wave reflection in stroke survivors. [2008.01]

Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects. [2008]

Is rasburicase an effective alternative to allopurinol for management of hyperuricemia in renal failure patients? A double blind-randomized study. [2007.05]

Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial. [2007.04]

Specific treatment for Trypanosoma cruzi: lack of efficacy of allopurinol in the human chronic phase of Chagas disease. [2007.01]

Effect of allopurinol supplementation on nitric oxide levels in asphyxiated newborns. [2007.01]

High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid. [2006.12.05]

Allopurinol as an adjunct to lithium and haloperidol for treatment of patients with acute mania: a double-blind, randomized, placebo-controlled trial. [2006.10]

Allopurinol improves endothelial function in sleep apnoea: a randomised controlled study. [2006.05]

Early postnatal allopurinol does not improve short term outcome after severe birth asphyxia. [2006.05]

Effect of allopurinol in chronic nonbacterial prostatitis: a double blind randomized clinical trial. [2006.03]

Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level. [2006.01]

Febuxostat compared with allopurinol in patients with hyperuricemia and gout. [2005.12.08]

The influence of allopurinol on urinary purine loss after repeated sprint exercise in man. [2005.10]

Oral allopurinol does not prevent the frequency or the severity of post-ERCP pancreatitis. [2005.08]

Periodic administration of allopurinol is not effective for the prevention of canine leishmaniosis (Leishmania infantum) in the endemic areas. [2005.06.30]

Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure. [2005.06]

High-dose allopurinol for prevention of post-ERCP pancreatitis: a prospective randomized double-blind controlled trial. [2005.03]

A clinical trial of adjuvant allopurinol therapy for moderately refractory schizophrenia. [2005.02]

Beneficial antipsychotic effects of allopurinol as add-on therapy for schizophrenia: a double blind, randomized and placebo controlled trial. [2005.02]

Ineffectiveness of allopurinol in reduction of oxidative stress in diabetic patients; a randomized, double-blind placebo-controlled clinical trial. [2004.12]

Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. [2004.12]

Effect of allopurinol pretreatment on free radical generation after primary coronary angioplasty for acute myocardial infarction. [2003.05]

Itraconazole or allopurinol in the treatment of chronic American trypanosomiasis: the regression and prevention of electrocardiographic abnormalities during 9 years of follow-up. [2003.01]

Intraluminal casein model of necrotizing enterocolitis for assessment of mucosal destruction, bacterial translocation, and the effects of allopurinol and N-acetylcysteine. [2002.12]

Evaluating the efficacy of allopurinol and meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis. [2002.08]

Allopurinol improves endothelial dysfunction in chronic heart failure. [2002.07.09]

The role of allopurinol in human liver ischemia/reperfusion injury: a prospective randomized clinical trial. [2002.07]

Treatment of cutaneous leishmaniasis with a combination of allopurinol and low-dose meglumine antimoniate. [2002.07]

Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies. [2002.06.04]

Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. [2002.04]

Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study. [2001.11]

A prospective, randomized, placebo-controlled trial of prednisone and allopurinol in the prevention of ERCP-induced pancreatitis. [2001.09]

A randomized clinical trial of low dosage combination of pentamidine and allopurinol in the treatment of antimony unresponsive cases of visceral leishmaniasis. [2001.06]

Well-designed clinical trials possibly related to Zyloprim (Allopurinol)

Uric acid reduction rectifies prehypertension in obese adolescents. [2012]

Rilonacept (interleukin-1 trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a phase II randomized, double-blind, placebo-controlled trial. [2012]

Clinical Outcome of Hyperuricemia in IgA Nephropathy: A Retrospective Cohort Study and Randomized Controlled Trial. [2011.11.23]

Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials. [2011.08.17]

Potential pharmacologic treatments for cystinuria and for calcium stones associated with hyperuricosuria. [2011.08]

Celsior versus University of Wisconsin preserving solutions for liver transplantation: postreperfusion syndrome and outcome of a 5-year prospective randomized controlled study. [2011.07]

Minimally important differences of the gout impact scale in a randomized controlled trial. [2011.07]

Metabolic muscle damage and oxidative stress markers in an America's Cup yachting crew. [2011.07]

Challenges of conducting a trial of uric-acid-lowering therapy in CKD. [2011.05]

Xanthine-oxidase inhibitors and statins in chronic heart failure: effects on vascular and functional parameters. [2011.04]

A randomized study comparing IGL-1 to the University of Wisconsin preservation solution in liver transplantation. [2010.12.22]

Effect of prophylaxis on gout flares after the initiation of urate-lowering therapy: analysis of data from three phase III trials. [2010.12]

Hypotension after reperfusion in liver transplantation: histidine-tryptophan-ketoglutarate versus University of Wisconsin solution. [2010.09]

Oral colchicine (Colcrys): in the treatment and prophylaxis of gout. [2010.08.20]

The URICO-ICTUS study, a phase 3 study of combined treatment with uric acid and rtPA administered intravenously in acute ischaemic stroke patients within the first 4.5 h of onset of symptoms. [2010.08]

Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer. [2010.06.16]

Effects of rosuvastatin on myeloperoxidase levels in patients with chronic heart failure: a randomized placebo-controlled study. [2010.05]

Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. [2010.03]

Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study. [2010.01]

The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. [2010]

Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study. [2010]

Serum urate during acute gout. [2009.06]

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