Index of reports
> Death (394)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Actemra (Tocilizumab) death. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 394 Next >>
Possible Actemra side effects in 47 year old female
Reported by a physician from Colombia on 2012-08-27
Patient: 47 year old female, weighing 50.0 kg (110.0 pounds)
Reactions: Pyrexia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Actemra
Dosage: date of last dose prior to sae : 13/jun/2012
Indication: Rheumatoid Arthritis
Start date: 2012-03-07
Actemra
Dosage: date of most recent dose prior to sae:22/feb/2012
Indication: Rheumatoid Arthritis
Start date: 2011-09-21
Other drugs received by patient: Chloroquine; Prednisolone; Omeprazole; Methotrexate; Diclofenac Sodium; Naproxen; Folic Acid; Acetaminophen
Possible Actemra side effects in male
Reported by a physician from Japan on 2012-08-25
Patient: male, weighing 56.0 kg (123.2 pounds)
Reactions: Dermatitis Allergic, Pruritus, Erythema, Fall, Death, Arthralgia, Injury, White Blood Cell Count Increased, Infection
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Prednisolone; Precipitated Calcium Carbonate; Levothyroxine Sodium; Allegra; Lasix; Sulfamethoxazole and Trimethoprim; Micardis; Vildagliptin; Bisoprolol Fumarate
Possible Actemra side effects in 47 year old female
Reported by a physician from Colombia on 2012-08-20
Patient: 47 year old female, weighing 59.8 kg (131.6 pounds)
Reactions: Pneumonia, Pyrexia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Actemra
Dosage: date of most recent dose prior to sae :22/feb/2012
Indication: Rheumatoid Arthritis
Start date: 2011-09-21
Roactemra
Dosage: date of last dose prior to sae : 13/jun/2012
Indication: Rheumatoid Arthritis
Start date: 2012-03-07
Other drugs received by patient: Omeprazole; Diclofenac; Folic Acid; Chloroquine; Acetaminophen; Prednisolone; Naproxen; Methotrexate
Possible Actemra side effects in 60 year old male
Reported by a physician from United States on 2012-08-20
Patient: 60 year old male, weighing 104.4 kg (229.6 pounds)
Reactions: Angina Pectoris, Injection Site Haematoma, Sinusitis, Deep Vein Thrombosis
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Dosage: most recent dose prior to sae: 01/feb/2012
Indication: Rheumatoid Arthritis
Start date: 2012-01-18
End date: 2012-02-14
Actemra
Dosage: most recent dose taken on 26/oct/2011
Indication: Rheumatoid Arthritis
Start date: 2011-08-03
End date: 2012-02-14
Other drugs received by patient: Folic Acid; Extra Strength Tylenol; Viagra; Methotrexate; Prednisone; Extra Strength Tylenol; Aspirin; Multi-Vitamin; Methotrexate; Prednisone; Multi-Vitamin; Zestril; Aspirin; Folic Acid
Possible Actemra side effects in 47 year old female
Reported by a physician from Colombia on 2012-08-17
Patient: 47 year old female, weighing 59.8 kg (131.6 pounds)
Reactions: Pneumonia, Pyrexia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Actemra
Dosage: date of most recent dose prior to sae :22/feb/2012
Indication: Rheumatoid Arthritis
Start date: 2011-09-21
Actemra
Dosage: date of last dose prior to sae : 13/jun/2012
Indication: Rheumatoid Arthritis
Start date: 2012-03-07
Other drugs received by patient: Acetaminophen; Prednisolone; Naproxen; Diclofenac; Methotrexate; Folic Acid; Omeprazole; Chloroquine
Possible Actemra side effects in male
Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-16
Patient: male
Reactions: Lung Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in 55 year old female
Reported by a physician from United Kingdom on 2012-08-16
Patient: 55 year old female
Reactions: Abscess Rupture
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in 10 year old male
Reported by a physician from Brazil on 2012-08-15
Patient: 10 year old male
Reactions: Toxoplasmosis
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in 51 year old female
Reported by a physician from Brazil on 2012-08-15
Patient: 51 year old female, weighing 48.0 kg (105.6 pounds)
Reactions: Pleural Effusion, Septic Shock, Lower Respiratory Tract Infection
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Folic Acid; Methotrexate; Prednisone TAB; Golimumab; Acetaminophen
Possible Actemra side effects in male
Reported by a individual with unspecified qualification from Japan on 2012-08-14
Patient: male, weighing 62.0 kg (136.4 pounds)
Reactions: Interstitial Lung Disease, Pneumothorax, Acute Respiratory Failure, Ankle Fracture
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Dosage: route: intravenous drip form: injection
Start date: 2008-06-11
End date: 2008-06-11
Actemra
Start date: 2008-07-10
End date: 2012-02-20
Actemra
Dosage: route: intravenous drip form: injection note: 560-600 mg/4weeks
Indication: Rheumatoid Arthritis
Start date: 2008-05-14
End date: 2009-10-14
Other drugs received by patient: Prednisolone; Prednisolone; Prednisolone; Prograf; Prednisolone; Prednisolone; Urso 250; Folic Acid; Prograf; Voltaren; Cytotec; Prednisolone
Possible Actemra side effects in male
Reported by a physician from Japan on 2012-08-10
Patient: male, weighing 26.0 kg (57.2 pounds)
Reactions: Pulmonary Haemorrhage, Histiocytosis Haematophagic, Hepatic Function Abnormal, Disseminated Intravascular Coagulation, Mumps, Liver Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Dosage: dosage is uncertain.
Start date: 2010-04-01
End date: 2010-04-01
Actemra
Dosage: dosage is uncertain.
Start date: 2010-04-19
End date: 2012-02-24
Actemra
Dosage: dosage is uncertain.
Indication: Juvenile Arthritis
Start date: 2010-03-23
End date: 2010-03-23
Other drugs received by patient: Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone
Possible Actemra side effects in 55 year old female
Reported by a physician from United Kingdom on 2012-08-10
Patient: 55 year old female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in 60 year old male
Reported by a physician from Japan on 2012-08-10
Patient: 60 year old male, weighing 73.0 kg (160.6 pounds)
Reactions: Death, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Lansoprazole; Folic Acid; Prednisolone; Methotrexate
Possible Actemra side effects in male
Reported by a physician from Hungary on 2012-08-08
Patient: male
Reactions: Respiratory Failure, Circulatory Collapse
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Tramadol HCL; Vitamin D; Citrokalcium; Metotrexat; Bisoprolol Fumarate; Huma-Folacid; Potassium Chloride; Medrol
Possible Actemra side effects in female
Reported by a physician from United Kingdom on 2012-08-08
Patient: female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in female
Reported by a physician from United States on 2012-08-08
Patient: female
Reactions: Myocardial Infarction
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Indication: Rheumatoid Arthritis
Rituxan
Indication: Rheumatoid Arthritis
Possible Actemra side effects in female
Reported by a physician from Argentina on 2012-08-07
Patient: female, weighing 60.0 kg (132.0 pounds)
Reactions: Pneumonia, Acute Respiratory Failure
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Hydroxychloroquine Sulfate; Methotrexate; Folic Acid; Naproxen; Prednisone
Possible Actemra side effects in female
Reported by a physician from Japan on 2012-08-06
Patient: female, weighing 45.0 kg (99.0 pounds)
Reactions: Vomiting, Hyponatraemia, Gastric Ulcer, Convulsion, Loss of Consciousness
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Prednisolone; Ketoprofen; Meilax; Zolpidem; Sennoside; Comelian; Prednisolone; Urepearl; Paxil; Tizanidine Hydrochloride; Omeprazole; Gasmotin; Alendronate Sodium; Ketoprofen
Possible Actemra side effects in male
Reported by a consumer/non-health professional from Brazil on 2012-08-06
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Weight Decreased, Anaemia, Abasia, Bone Erosion, Weight Increased, Death, Limb Deformity, Rheumatoid Arthritis, Swelling
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Dosage: dose: 680 mg.
Indication: Rheumatoid Arthritis
Start date: 2009-10-01
End date: 2011-05-01
Actemra
Cyclosporine
Indication: Product Used FOR Unknown Indication
Leflunomide
Dosage: freq: 1 tablet at night.
Indication: Product Used FOR Unknown Indication
Possible Actemra side effects in female
Reported by a physician from Argentina on 2012-08-03
Patient: female, weighing 60.0 kg (132.0 pounds)
Reactions: Pneumonia, Acute Respiratory Failure
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Prednisone; Naproxen; Hydroxychloroquine Sulfate; Methotrexate; Folic Acid
Possible Actemra side effects in female
Reported by a physician from Japan on 2012-08-03
Patient: female
Reactions: Interstitial Lung Disease
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Dosage: 456-464mg
Start date: 2009-07-21
End date: 2010-02-23
Actemra
Dosage: 440-472mg
Indication: Rheumatoid Arthritis
Start date: 2008-09-09
End date: 2009-05-19
Actemra
Start date: 2010-04-06
End date: 2010-04-06
Other drugs received by patient: Mobic; Rheumatrex; Famotidine
Possible Actemra side effects in female
Reported by a physician from Japan on 2012-07-31
Patient: female
Reactions: Arthralgia, Disseminated Intravascular Coagulation, Spinal Cord Injury, Lumbar Spinal Stenosis, Cerebral Haemorrhage
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Actemra
Indication: Rheumatoid Arthritis
Start date: 2009-06-29
End date: 2009-06-29
Actemra
Start date: 2009-08-27
End date: 2009-08-27
Actemra
Start date: 2010-05-17
End date: 2010-05-17
Actemra
Start date: 2009-07-30
End date: 2009-07-30
Actemra
Start date: 2010-03-23
End date: 2010-03-23
Actemra
Start date: 2010-06-14
End date: 2010-06-14
Actemra
Start date: 2009-10-22
End date: 2009-10-22
Actemra
Start date: 2009-11-19
End date: 2009-11-19
Actemra
Start date: 2010-07-12
End date: 2011-08-23
Actemra
Start date: 2010-04-19
End date: 2010-04-19
Actemra
Start date: 2009-09-24
End date: 2009-09-24
Actemra
Start date: 2009-12-17
End date: 2009-12-17
Actemra
Start date: 2011-09-21
End date: 2011-09-21
Actemra
Start date: 2011-10-20
End date: 2011-10-20
Actemra
Start date: 2010-01-14
End date: 2010-02-15
Prednisolone
Dosage: form:por
Administration route: Oral
Start date: 2009-04-20
End date: 2009-08-26
Prednisolone
Dosage: form:por
Administration route: Oral
Start date: 2009-09-24
Prednisolone
Dosage: form:por
Administration route: Oral
Indication: Rheumatoid Arthritis
End date: 2009-04-19
Prednisolone
Dosage: form:por
Administration route: Oral
Start date: 2009-08-27
End date: 2009-09-23
Prednisolone
Dosage: form:por
Administration route: Oral
End date: 2011-11-20
Other drugs received by patient: Diltiazem HCL; Rabeprazole Sodium; Actonel; Onealfa; Clarithromycin; Evista; Hicee; Etodolac; Vitamin B12; Voltaren; Lendormin D
Possible Actemra side effects in 60 year old male
Reported by a physician from Japan on 2012-07-31
Patient: 60 year old male, weighing 73.0 kg (160.6 pounds)
Reactions: Drowning, Embolism, Sepsis, Myocardial Infarction
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Folic Acid; Prednisolone; Lansoprazole; Methotrexate
Possible Actemra side effects in female
Reported by a physician from Japan on 2012-07-31
Patient: female
Reactions: Aortic Aneurysm Rupture, Arterioenteric Fistula, Abscess
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Pursennid; Lendormin; Urso 250; Mucosta; Alosenn; Marzulene; Protecadin; Prednisolone; Prednisolone
Possible Actemra side effects in male
Reported by a physician from United States on 2012-07-30
Patient: male
Reactions: Respiratory Failure, Pulmonary Fibrosis
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Methotrexate
Possible Actemra side effects in female
Reported by a physician from Japan on 2012-07-27
Patient: female, weighing 69.2 kg (152.2 pounds)
Reactions: Death, Hyperlipidaemia, Renal Cell Carcinoma, Hepatic Function Abnormal, Joint Effusion
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Actemra
Dosage: dosage is uncertain
Indication: Rheumatoid Arthritis
Start date: 2008-08-26
End date: 2008-08-26
Infliximab
Indication: Rheumatoid Arthritis
Start date: 2007-09-19
End date: 2008-07-31
Methotrexate Sodium
Dosage: divided into 2 doses.
Administration route: Oral
Start date: 2009-02-11
End date: 2010-09-01
Methotrexate Sodium
Administration route: Oral
Start date: 2009-01-14
End date: 2009-02-10
Methotrexate Sodium
Dosage: divided into 2 doses
Administration route: Oral
Indication: Rheumatoid Arthritis
Other drugs received by patient: Norvasc; Dexamethasone; Prednisolone; Folic Acid; Prednisolone; Norvasc; Protecadin; Folic Acid; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Alendronate Sodium; Amlodipine; Rimatil; Prednisolone; Voltaren
Possible Actemra side effects in male
Reported by a physician from Denmark on 2012-07-27
Patient: male, weighing 71.0 kg (156.2 pounds)
Reactions: Pneumonia, Cardiac Failure, Disseminated Intravascular Coagulation, Pleural Effusion, Acute Myocardial Infarction, Cardiogenic Shock, Staphylococcal Sepsis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Actemra
Start date: 2011-11-03
Actemra
Dosage: startdosis 8 mg/kg.
Indication: Rheumatoid Arthritis
Start date: 2010-08-27
End date: 2012-02-23
Actemra
Start date: 2011-11-30
Actemra
Start date: 2012-01-11
Actemra
Start date: 2012-02-23
Methotrexate
Dosage: behandling stoppet pga. mors, drug reported as emthexate, cumulative dose 7776.51785
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2002-04-04
Prednisolone
Dosage: behandling stoppet pga. mors, cumulative dose 27217.8125
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2002-04-04
Possible Actemra side effects in male
Reported by a physician from Germany on 2012-07-27
Patient: male
Reactions: Metastatic Bronchial Carcinoma
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Other drugs received by patient: Methotrexate; Golimumab; Sulfasalazine; Methotrexate; Cimzia
Possible Actemra side effects in
Reported by a consumer/non-health professional from United States on 2012-07-27
Patient:
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Possible Actemra side effects in 76 year old female
Reported by a physician from Sweden on 2012-07-27
Patient: 76 year old female
Reactions: Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Actemra
Page 1 Next >>
|