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Actemra (Tocilizumab) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Death (394)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Actemra (Tocilizumab) death. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 394   Next >>

Possible Actemra side effects in 47 year old female

Reported by a physician from Colombia on 2012-08-27

Patient: 47 year old female, weighing 50.0 kg (110.0 pounds)

Reactions: Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Actemra
    Dosage: date of last dose prior to sae : 13/jun/2012
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-07

Actemra
    Dosage: date of most recent dose prior to sae:22/feb/2012
    Indication: Rheumatoid Arthritis
    Start date: 2011-09-21

Other drugs received by patient: Chloroquine; Prednisolone; Omeprazole; Methotrexate; Diclofenac Sodium; Naproxen; Folic Acid; Acetaminophen



Possible Actemra side effects in male

Reported by a physician from Japan on 2012-08-25

Patient: male, weighing 56.0 kg (123.2 pounds)

Reactions: Dermatitis Allergic, Pruritus, Erythema, Fall, Death, Arthralgia, Injury, White Blood Cell Count Increased, Infection

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Prednisolone; Precipitated Calcium Carbonate; Levothyroxine Sodium; Allegra; Lasix; Sulfamethoxazole and Trimethoprim; Micardis; Vildagliptin; Bisoprolol Fumarate



Possible Actemra side effects in 47 year old female

Reported by a physician from Colombia on 2012-08-20

Patient: 47 year old female, weighing 59.8 kg (131.6 pounds)

Reactions: Pneumonia, Pyrexia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra
    Dosage: date of most recent dose prior to sae :22/feb/2012
    Indication: Rheumatoid Arthritis
    Start date: 2011-09-21

Roactemra
    Dosage: date of last dose prior to sae : 13/jun/2012
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-07

Other drugs received by patient: Omeprazole; Diclofenac; Folic Acid; Chloroquine; Acetaminophen; Prednisolone; Naproxen; Methotrexate



Possible Actemra side effects in 60 year old male

Reported by a physician from United States on 2012-08-20

Patient: 60 year old male, weighing 104.4 kg (229.6 pounds)

Reactions: Angina Pectoris, Injection Site Haematoma, Sinusitis, Deep Vein Thrombosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Dosage: most recent dose prior to sae: 01/feb/2012
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-18
    End date: 2012-02-14

Actemra
    Dosage: most recent dose taken on 26/oct/2011
    Indication: Rheumatoid Arthritis
    Start date: 2011-08-03
    End date: 2012-02-14

Other drugs received by patient: Folic Acid; Extra Strength Tylenol; Viagra; Methotrexate; Prednisone; Extra Strength Tylenol; Aspirin; Multi-Vitamin; Methotrexate; Prednisone; Multi-Vitamin; Zestril; Aspirin; Folic Acid



Possible Actemra side effects in 47 year old female

Reported by a physician from Colombia on 2012-08-17

Patient: 47 year old female, weighing 59.8 kg (131.6 pounds)

Reactions: Pneumonia, Pyrexia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra
    Dosage: date of most recent dose prior to sae :22/feb/2012
    Indication: Rheumatoid Arthritis
    Start date: 2011-09-21

Actemra
    Dosage: date of last dose prior to sae : 13/jun/2012
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-07

Other drugs received by patient: Acetaminophen; Prednisolone; Naproxen; Diclofenac; Methotrexate; Folic Acid; Omeprazole; Chloroquine



Possible Actemra side effects in male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-16

Patient: male

Reactions: Lung Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in 55 year old female

Reported by a physician from United Kingdom on 2012-08-16

Patient: 55 year old female

Reactions: Abscess Rupture

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in 10 year old male

Reported by a physician from Brazil on 2012-08-15

Patient: 10 year old male

Reactions: Toxoplasmosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in 51 year old female

Reported by a physician from Brazil on 2012-08-15

Patient: 51 year old female, weighing 48.0 kg (105.6 pounds)

Reactions: Pleural Effusion, Septic Shock, Lower Respiratory Tract Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Folic Acid; Methotrexate; Prednisone TAB; Golimumab; Acetaminophen



Possible Actemra side effects in male

Reported by a individual with unspecified qualification from Japan on 2012-08-14

Patient: male, weighing 62.0 kg (136.4 pounds)

Reactions: Interstitial Lung Disease, Pneumothorax, Acute Respiratory Failure, Ankle Fracture

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Dosage: route: intravenous drip form: injection
    Start date: 2008-06-11
    End date: 2008-06-11

Actemra
    Start date: 2008-07-10
    End date: 2012-02-20

Actemra
    Dosage: route: intravenous drip form: injection note: 560-600 mg/4weeks
    Indication: Rheumatoid Arthritis
    Start date: 2008-05-14
    End date: 2009-10-14

Other drugs received by patient: Prednisolone; Prednisolone; Prednisolone; Prograf; Prednisolone; Prednisolone; Urso 250; Folic Acid; Prograf; Voltaren; Cytotec; Prednisolone



Possible Actemra side effects in male

Reported by a physician from Japan on 2012-08-10

Patient: male, weighing 26.0 kg (57.2 pounds)

Reactions: Pulmonary Haemorrhage, Histiocytosis Haematophagic, Hepatic Function Abnormal, Disseminated Intravascular Coagulation, Mumps, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Dosage: dosage is uncertain.
    Start date: 2010-04-01
    End date: 2010-04-01

Actemra
    Dosage: dosage is uncertain.
    Start date: 2010-04-19
    End date: 2012-02-24

Actemra
    Dosage: dosage is uncertain.
    Indication: Juvenile Arthritis
    Start date: 2010-03-23
    End date: 2010-03-23

Other drugs received by patient: Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Prednisolone



Possible Actemra side effects in 55 year old female

Reported by a physician from United Kingdom on 2012-08-10

Patient: 55 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in 60 year old male

Reported by a physician from Japan on 2012-08-10

Patient: 60 year old male, weighing 73.0 kg (160.6 pounds)

Reactions: Death, Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Lansoprazole; Folic Acid; Prednisolone; Methotrexate



Possible Actemra side effects in male

Reported by a physician from Hungary on 2012-08-08

Patient: male

Reactions: Respiratory Failure, Circulatory Collapse

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Tramadol HCL; Vitamin D; Citrokalcium; Metotrexat; Bisoprolol Fumarate; Huma-Folacid; Potassium Chloride; Medrol



Possible Actemra side effects in female

Reported by a physician from United Kingdom on 2012-08-08

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in female

Reported by a physician from United States on 2012-08-08

Patient: female

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis

Rituxan
    Indication: Rheumatoid Arthritis



Possible Actemra side effects in female

Reported by a physician from Argentina on 2012-08-07

Patient: female, weighing 60.0 kg (132.0 pounds)

Reactions: Pneumonia, Acute Respiratory Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Hydroxychloroquine Sulfate; Methotrexate; Folic Acid; Naproxen; Prednisone



Possible Actemra side effects in female

Reported by a physician from Japan on 2012-08-06

Patient: female, weighing 45.0 kg (99.0 pounds)

Reactions: Vomiting, Hyponatraemia, Gastric Ulcer, Convulsion, Loss of Consciousness

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Prednisolone; Ketoprofen; Meilax; Zolpidem; Sennoside; Comelian; Prednisolone; Urepearl; Paxil; Tizanidine Hydrochloride; Omeprazole; Gasmotin; Alendronate Sodium; Ketoprofen



Possible Actemra side effects in male

Reported by a consumer/non-health professional from Brazil on 2012-08-06

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Weight Decreased, Anaemia, Abasia, Bone Erosion, Weight Increased, Death, Limb Deformity, Rheumatoid Arthritis, Swelling

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Dosage: dose: 680 mg.
    Indication: Rheumatoid Arthritis
    Start date: 2009-10-01
    End date: 2011-05-01

Actemra

Cyclosporine
    Indication: Product Used FOR Unknown Indication

Leflunomide
    Dosage: freq: 1 tablet at night.
    Indication: Product Used FOR Unknown Indication



Possible Actemra side effects in female

Reported by a physician from Argentina on 2012-08-03

Patient: female, weighing 60.0 kg (132.0 pounds)

Reactions: Pneumonia, Acute Respiratory Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Prednisone; Naproxen; Hydroxychloroquine Sulfate; Methotrexate; Folic Acid



Possible Actemra side effects in female

Reported by a physician from Japan on 2012-08-03

Patient: female

Reactions: Interstitial Lung Disease

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra
    Dosage: 456-464mg
    Start date: 2009-07-21
    End date: 2010-02-23

Actemra
    Dosage: 440-472mg
    Indication: Rheumatoid Arthritis
    Start date: 2008-09-09
    End date: 2009-05-19

Actemra
    Start date: 2010-04-06
    End date: 2010-04-06

Other drugs received by patient: Mobic; Rheumatrex; Famotidine



Possible Actemra side effects in female

Reported by a physician from Japan on 2012-07-31

Patient: female

Reactions: Arthralgia, Disseminated Intravascular Coagulation, Spinal Cord Injury, Lumbar Spinal Stenosis, Cerebral Haemorrhage

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis
    Start date: 2009-06-29
    End date: 2009-06-29

Actemra
    Start date: 2009-08-27
    End date: 2009-08-27

Actemra
    Start date: 2010-05-17
    End date: 2010-05-17

Actemra
    Start date: 2009-07-30
    End date: 2009-07-30

Actemra
    Start date: 2010-03-23
    End date: 2010-03-23

Actemra
    Start date: 2010-06-14
    End date: 2010-06-14

Actemra
    Start date: 2009-10-22
    End date: 2009-10-22

Actemra
    Start date: 2009-11-19
    End date: 2009-11-19

Actemra
    Start date: 2010-07-12
    End date: 2011-08-23

Actemra
    Start date: 2010-04-19
    End date: 2010-04-19

Actemra
    Start date: 2009-09-24
    End date: 2009-09-24

Actemra
    Start date: 2009-12-17
    End date: 2009-12-17

Actemra
    Start date: 2011-09-21
    End date: 2011-09-21

Actemra
    Start date: 2011-10-20
    End date: 2011-10-20

Actemra
    Start date: 2010-01-14
    End date: 2010-02-15

Prednisolone
    Dosage: form:por
    Administration route: Oral
    Start date: 2009-04-20
    End date: 2009-08-26

Prednisolone
    Dosage: form:por
    Administration route: Oral
    Start date: 2009-09-24

Prednisolone
    Dosage: form:por
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    End date: 2009-04-19

Prednisolone
    Dosage: form:por
    Administration route: Oral
    Start date: 2009-08-27
    End date: 2009-09-23

Prednisolone
    Dosage: form:por
    Administration route: Oral
    End date: 2011-11-20

Other drugs received by patient: Diltiazem HCL; Rabeprazole Sodium; Actonel; Onealfa; Clarithromycin; Evista; Hicee; Etodolac; Vitamin B12; Voltaren; Lendormin D



Possible Actemra side effects in 60 year old male

Reported by a physician from Japan on 2012-07-31

Patient: 60 year old male, weighing 73.0 kg (160.6 pounds)

Reactions: Drowning, Embolism, Sepsis, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Folic Acid; Prednisolone; Lansoprazole; Methotrexate



Possible Actemra side effects in female

Reported by a physician from Japan on 2012-07-31

Patient: female

Reactions: Aortic Aneurysm Rupture, Arterioenteric Fistula, Abscess

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Pursennid; Lendormin; Urso 250; Mucosta; Alosenn; Marzulene; Protecadin; Prednisolone; Prednisolone



Possible Actemra side effects in male

Reported by a physician from United States on 2012-07-30

Patient: male

Reactions: Respiratory Failure, Pulmonary Fibrosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Methotrexate



Possible Actemra side effects in female

Reported by a physician from Japan on 2012-07-27

Patient: female, weighing 69.2 kg (152.2 pounds)

Reactions: Death, Hyperlipidaemia, Renal Cell Carcinoma, Hepatic Function Abnormal, Joint Effusion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Actemra
    Dosage: dosage is uncertain
    Indication: Rheumatoid Arthritis
    Start date: 2008-08-26
    End date: 2008-08-26

Infliximab
    Indication: Rheumatoid Arthritis
    Start date: 2007-09-19
    End date: 2008-07-31

Methotrexate Sodium
    Dosage: divided into 2 doses.
    Administration route: Oral
    Start date: 2009-02-11
    End date: 2010-09-01

Methotrexate Sodium
    Administration route: Oral
    Start date: 2009-01-14
    End date: 2009-02-10

Methotrexate Sodium
    Dosage: divided into 2 doses
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Norvasc; Dexamethasone; Prednisolone; Folic Acid; Prednisolone; Norvasc; Protecadin; Folic Acid; Prednisolone; Prednisolone; Prednisolone; Prednisolone; Alendronate Sodium; Amlodipine; Rimatil; Prednisolone; Voltaren



Possible Actemra side effects in male

Reported by a physician from Denmark on 2012-07-27

Patient: male, weighing 71.0 kg (156.2 pounds)

Reactions: Pneumonia, Cardiac Failure, Disseminated Intravascular Coagulation, Pleural Effusion, Acute Myocardial Infarction, Cardiogenic Shock, Staphylococcal Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Actemra
    Start date: 2011-11-03

Actemra
    Dosage: startdosis 8 mg/kg.
    Indication: Rheumatoid Arthritis
    Start date: 2010-08-27
    End date: 2012-02-23

Actemra
    Start date: 2011-11-30

Actemra
    Start date: 2012-01-11

Actemra
    Start date: 2012-02-23

Methotrexate
    Dosage: behandling stoppet pga. mors, drug reported as emthexate, cumulative dose 7776.51785
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2002-04-04

Prednisolone
    Dosage: behandling stoppet pga. mors, cumulative dose 27217.8125
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2002-04-04



Possible Actemra side effects in male

Reported by a physician from Germany on 2012-07-27

Patient: male

Reactions: Metastatic Bronchial Carcinoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra

Other drugs received by patient: Methotrexate; Golimumab; Sulfasalazine; Methotrexate; Cimzia



Possible Actemra side effects in

Reported by a consumer/non-health professional from United States on 2012-07-27

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



Possible Actemra side effects in 76 year old female

Reported by a physician from Sweden on 2012-07-27

Patient: 76 year old female

Reactions: Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Actemra



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