This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Alcaine (Proparacaine) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (52)
Disability (6)
Reports by Reaction Type
Drug Abuse (39),
Eye Pain (30),
Corneal Epithelium Defect (27),
Conjunctival Hyperaemia (23),
Photophobia (22),
Lacrimation Increased (21),
Ulcerative Keratitis (15),
Keratopathy (14),
Hypopyon (13),
Visual Acuity Reduced (9),
Corneal Infiltrates (9),
Corneal Oedema (9)
Below are a few examples of reports where side effects / adverse reactions may be related to Alcaine (Proparacaine). For a complete list or a specific selection of reports, please use the links above.
Possible Alcaine side effects in 38 year old female
Reported by a physician from Turkey on 2012-07-12
Patient: 38 year old female
Reactions: Eyelid Oedema, Corneal Opacity, Treatment Noncompliance, Drug Abuse, Corneal Epithelium Defect, Eye Pain, Sensation of Foreign Body, Ocular Hyperaemia, Lacrimation Increased, Keratitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 25 year old female
Reported by a physician from Turkey on 2012-06-05
Patient: 25 year old female
Reactions: Corneal Perforation, Corneal Erosion, Eye Pain
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 25 year old female
Reported by a physician from Turkey on 2012-05-10
Patient: 25 year old female
Reactions: Corneal Perforation, Corneal Erosion
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 75 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-07
Patient: 75 year old female, weighing 63.0 kg (138.7 pounds)
Reactions: Medication Error, Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
BSS
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Alcaine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Ciloxan
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Mydriacyl
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Betadine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Other drugs received by patient: Epinephrine; Vancomycin; Ocufen; Phenylephrine HCL
Possible Alcaine side effects in 63 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-07
Patient: 63 year old male, weighing 70.3 kg (154.7 pounds)
Reactions: Medication Error, Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
Alcaine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
BSS
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Cyclogyl
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Betadine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Other drugs received by patient: Epinephrine; Vancomycin; Phenylephrine HCL; Ocufen
Possible Alcaine side effects in 25 year old female
Reported by a physician from Turkey on 2012-05-01
Patient: 25 year old female
Reactions: Corneal Perforation, Corneal Erosion, Eye Pain
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 75 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-18
Patient: 75 year old female, weighing 63.0 kg (138.7 pounds)
Reactions: Post Procedural Complication, Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
Mydriacyl
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Betadine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Ciloxan
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
BSS
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Alcaine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-19
End date: 2012-03-19
Other drugs received by patient: Phenylephrine HCL; Ocufen; Vancomycin; Epinephrine
Possible Alcaine side effects in 63 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-18
Patient: 63 year old male, weighing 70.3 kg (154.7 pounds)
Reactions: Post Procedural Complication, Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
Betadine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Alcaine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
BSS
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Cyclogyl
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-03-21
End date: 2012-03-21
Other drugs received by patient: Vancomycin; Phenylephrine HCL; Ocufen; Epinephrine
Possible Alcaine side effects in 86 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-28
Patient: 86 year old male, weighing 85.3 kg (187.6 pounds)
Reactions: Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
BSS
Dosage: intraocular
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
BSS Plus
Dosage: intraocular
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Cyclogyl
Dosage: ophthalmic
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Alcaine
Dosage: ophthalmic
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Betadine
Dosage: ophthalmic
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Other drugs received by patient: Zymaxid; Tropicamide; Phenylephrine HCL; Other Antiglaucoma Preparations
Possible Alcaine side effects in 86 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-01
Patient: 86 year old male, weighing 85.3 kg (187.6 pounds)
Reactions: Post Procedural Complication, Toxic Anterior Segment Syndrome
Drug(s) suspected as cause:
Alcaine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
BSS
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Cyclogyl
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Betadine
Dosage: (ophthalmic)
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
BSS Plus
Dosage: (intraocular)
Indication: Intraocular Lens Implant
Start date: 2012-02-06
End date: 2012-02-06
Other drugs received by patient: Phenylephrine; Tropicamide; Zymaxid; Other Antiglaucoma Preparations
Possible Alcaine side effects in 54 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-02-14
Patient: 54 year old female
Reactions: Syncope, Fatigue, Asthenia, Convulsion
Drug(s) suspected as cause:
Alcaine
Other drugs received by patient: Fluorescein; Naproxin; Ratio-Meloxicam; Synthroid; Venlafaxine; Nexium; Phenobarbital TAB; Dilantin
Possible Alcaine side effects in 29 year old male
Reported by a physician from Turkey on 2012-02-08
Patient: 29 year old male
Reactions: Corneal Thinning, Eye Irritation, Necrosis, Keratopathy, Transplant Rejection, Corneal Opacity, Drug Abuse, Corneal Epithelium Defect, Eye Pain, Corneal Infiltrates
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 36 year old male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-02-08
Patient: 36 year old male
Reactions: Corneal Thinning, Amniotic Membrane Graft, Ulcerative Keratitis, Visual Acuity Reduced, Corneal Opacity, Drug Abuse, Hypopyon, Corneal Infiltrates, Photophobia, Ocular Hyperaemia, Infectious Crystalline Keratopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 36 year old male
Reported by a physician from Turkey on 2012-02-08
Patient: 36 year old male
Reactions: Corneal Thinning, Eyelid Oedema, Corneal Infiltrates, Keratopathy, Conjunctival Hyperaemia, Ulcerative Keratitis, Corneal Opacity, Drug Abuse
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 20 year old male
Reported by a physician from Turkey on 2012-02-08
Patient: 20 year old male
Reactions: Keratopathy, Ulcerative Keratitis, Drug Abuse, Eye Pain, Hypopyon, Corneal Infiltrates, Corneal Scar, Photophobia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 37 year old
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-02-06
Patient: 37 year old
Reactions: Keratopathy, Drug Abuse, Corneal Leukoma
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 30 year old
Reported by a physician from Turkey on 2012-02-06
Patient: 30 year old
Reactions: Glaucoma, Keratopathy, Toxicity To Various Agents, Drug Abuse
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 19 year old male
Reported by a physician from Turkey on 2012-02-06
Patient: 19 year old male
Reactions: Corneal Infiltrates, Keratopathy, Toxicity To Various Agents, Drug Abuse, Corneal Epithelium Defect, Corneal Leukoma
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 28 year old
Reported by a physician from Turkey on 2012-02-06
Patient: 28 year old
Reactions: Keratopathy, Toxicity To Various Agents, Drug Abuse, Corneal Leukoma
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 45 year old male
Reported by a physician from Turkey on 2012-02-06
Patient: 45 year old male
Reactions: Keratopathy, Toxicity To Various Agents, Corneal Epithelium Defect, Drug Abuse, Eye Pain, Corneal Leukoma, Corneal Infiltrates, Hypopyon, Photophobia, Vision Blurred
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 30 year old
Reported by a physician from Turkey on 2012-02-06
Patient: 30 year old
Reactions: Keratopathy, Toxicity To Various Agents, Drug Abuse, Corneal Leukoma
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 28 year old
Reported by a physician from Turkey on 2012-02-06
Patient: 28 year old
Reactions: Keratopathy, Toxicity To Various Agents, Drug Abuse, Corneal Leukoma
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 29 year old male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-02-03
Patient: 29 year old male
Reactions: Corneal Thinning, Eye Irritation, Necrosis, Keratopathy, Transplant Rejection, Toxicity To Various Agents, Corneal Opacity, Corneal Epithelium Defect, Drug Abuse, Eye Pain, Corneal Infiltrates
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 54 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-01-19
Patient: 54 year old female
Reactions: Syncope, Fatigue, Asthenia, Convulsion
Drug(s) suspected as cause:
Alcaine
Other drugs received by patient: Fluorescein ( TO Continuing)
Possible Alcaine side effects in 65 year old male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-12-20
Patient: 65 year old male
Reactions: Legal Problem, Corneal Neovascularisation, Keratopathy, Visual Acuity Reduced, Treatment Noncompliance, Drug Abuse, Corneal Epithelium Defect, Hypopyon, Corneal Infiltrates, Corneal Oedema, Iritis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in 78 year old female
Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2011-12-14
Patient: 78 year old female, weighing 90.0 kg (198.0 pounds)
Reactions: Off Label Use, Corneal Erosion
Drug(s) suspected as cause:
Vigamox
Dosage: (2 drops after phacoemulsification ophthalmic)
Indication: Infection Prophylaxis
Start date: 2011-11-24
End date: 2011-11-24
Alcaine
Dosage: (ophthalmic)
Start date: 2011-11-24
End date: 2011-11-24
Possible Alcaine side effects in 85 year old female
Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2011-12-14
Patient: 85 year old female, weighing 60.0 kg (132.0 pounds)
Reactions: Off Label Use, Corneal Erosion
Drug(s) suspected as cause:
Vigamox
Dosage: (2 drops after phacoemulsification, ophthalmic)
Indication: Infection Prophylaxis
Start date: 2011-11-24
End date: 2011-11-24
Alcaine
Dosage: (ophthalmic)
Start date: 2011-11-24
End date: 2011-11-24
Possible Alcaine side effects in male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-11-14
Patient: male
Reactions: Vitreous Prolapse, Hypopyon, Lens Dislocation, Conjunctival Hyperaemia, Visual Acuity Reduced, Ulcerative Keratitis, Corneal Opacity, Drug Abuse, Corneal Epithelium Defect, Eye Pain
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-11-14
Patient: male
Reactions: Eyelid Oedema, Drug Ineffective, Visual Acuity Reduced, Corneal Epithelium Defect, Drug Abuse, Eye Pain, Conjunctival Hyperaemia, Ocular Hyperaemia, Keratitis Viral, Drug Dependence, Eye Pruritus
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Alcaine
Possible Alcaine side effects in male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2011-11-14
Patient: male
Reactions: Eyelid Oedema, Erythema of Eyelid, Eye Irritation, Visual Acuity Reduced, Drug Abuse, Corneal Epithelium Defect, Corneal Deposits, Eye Pain, Corneal Infiltrates, Conjunctival Hyperaemia, Ocular Hyperaemia, Lacrimation Increased
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Alcaine
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