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Avastin (Bevacizumab) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (250)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 250   Next >>

Possible Avastin side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-27

Patient:

Reactions: Electrocardiogram QT Prolonged, Proctitis, Rhabdomyolysis, Gastrointestinal Haemorrhage, Hyperbilirubinaemia, Hypokalaemia, Neuropathy Peripheral, Intestinal Perforation, Fatigue, Proteinuria, Thrombocytopenia, Azotaemia, Hypovolaemia, Blood Alkaline Phosphatase Increased, Fistula, Stomatitis, Hyperglycaemia, Hyponatraemia, Hyperlipidaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Neutropenia, Abscess, Vaginal Infection, Hypertension

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic

Everolimus
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in 62 year old female

Reported by a physician from United States on 2012-08-27

Patient: 62 year old female

Reactions: Mucosal Inflammation, Fatigue, Diarrhoea, Mental Status Changes, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic

Xeloda
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in 63 year old female

Reported by a physician from France on 2012-08-23

Patient: 63 year old female

Reactions: Partial Seizures, Diarrhoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Glioblastoma
    Start date: 2011-04-20

Irinotecan Mayne
    Indication: Glioblastoma
    Start date: 2011-04-20
    End date: 2011-05-18

Other drugs received by patient: Irinotecan Hydrochloride; Methylprednisolone Hemisuccinate; Zofran



Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-22

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Potassium Chloride; Norfloxacin; Dolpasse



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient:

Reactions: Gastrointestinal Haemorrhage, Hyperbilirubinaemia, Anaemia, Alanine Aminotransferase Increased, Rash, Gastritis, Breast Cancer Metastatic, Diarrhoea, Ejection Fraction Decreased, Aspartate Aminotransferase Increased, Hypertension

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: every 2 weeks
    Indication: Breast Cancer Metastatic

Lapatinib
    Administration route: Oral
    Indication: Breast Cancer Metastatic



Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Asthma, Productive Cough, Urinary Incontinence, Bronchial Carcinoma, Aphasia, Rash Pruritic, Off Label Use, Poor Quality Sleep, Death, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Stomatitis, Vomiting, Pneumonia, Dyspnoea, Blood Urea Increased, Nausea, Rhinorrhoea, Rash, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Rectal Cancer Metastatic

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Productive Cough, Aphasia, Bronchial Carcinoma, Rash Pruritic, Poor Quality Sleep, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Dyspnoea, Blood Urea Increased, Stomatitis, Vomiting, Nausea, Rhinorrhoea, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic

Tarceva
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-20

Patient: female, weighing 71.0 kg (156.2 pounds)

Reactions: Death, Dyspnoea, Pneumonia, Diarrhoea, Hyperkalaemia, Cardiac Failure, Pleural Effusion

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2011-01-10
    End date: 2012-02-14

Avastin
    Indication: Colorectal Cancer

Fluorouracil
    Start date: 2011-01-10
    End date: 2012-02-14

Fluorouracil
    Indication: Colorectal Cancer

Irinotecan Hydrochloride
    Indication: Colorectal Cancer

Leucovorin Calcium
    Indication: Colorectal Cancer

Leucovorin Calcium
    Start date: 2011-01-10
    End date: 2012-02-14



Possible Avastin side effects in female

Reported by a physician from Portugal on 2012-08-20

Patient: female, weighing 59.0 kg (129.8 pounds)

Reactions: Diarrhoea, Dehydration, Blood Creatinine Increased

Drug(s) suspected as cause:
Avastin
    Dosage: over 30-90 minutes
    Indication: Colorectal Cancer
    Start date: 2010-01-25
    End date: 2010-03-08

Avastin

Fluorouracil
    Dosage: over 46-48 hours.

Fluorouracil
    Dosage: on every day 01. followed by 2400 mg/m2
    Indication: Colorectal Cancer
    Start date: 2010-01-25
    End date: 2010-03-08

Oxaliplatin

Oxaliplatin
    Dosage: on day 01 of every 14 days cycle.
    Indication: Colorectal Cancer
    Start date: 2010-01-25
    End date: 2010-03-08

Other drugs received by patient: Albuterol Sulate; Leucovorin Calcium; Drill; Allopurinol; Acetaminophen; Altizide + Spironolactone; Leucovorin Calcium; Loperamide HCL



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-17

Patient: male, weighing 64.0 kg (140.8 pounds)

Reactions: Performance Status Decreased, Diarrhoea, Pyrexia, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2011-05-12

Avastin
    Indication: Lung Neoplasm Malignant
    Start date: 2011-04-21

Docetaxel
    Indication: Lung Neoplasm Malignant
    Start date: 2012-02-01
    End date: 2012-02-08



Possible Avastin side effects in 62 year old male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 62 year old male, weighing 64.9 kg (142.8 pounds)

Reactions: Death, Diarrhoea, Dehydration, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-16

Patient: male

Reactions: Diarrhoea, Rectal Haemorrhage, Asthenia, Epistaxis, Disease Progression

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Leucovorin Calcium; Fluorouracil; Irinotecan Hydrochloride



Possible Avastin side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-16

Patient: male, weighing 51.8 kg (113.9 pounds)

Reactions: Peripheral Coldness, Nausea, Skin Exfoliation, Pain in Extremity, Hypoaesthesia, DRY Skin, Erythema, Dysgeusia, Protein Urine, Fatigue, Diarrhoea, Skin Discolouration, Feeling Hot, Decreased Appetite

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01

Xeloda
    Dosage: 2000mg in morning, 1500 mg in night
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-03-01
    End date: 2012-07-01



Possible Avastin side effects in male

Reported by a physician from Canada on 2012-08-16

Patient: male, weighing 60.8 kg (133.8 pounds)

Reactions: Diarrhoea, Rectal Haemorrhage, Amnesia, Hypersomnia

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Dexamethasone; Dilantin



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-13

Patient:

Reactions: Abdominal Pain, Blood Bilirubin Increased, Thrombosis, Anal Examination Abnormal, Hypokalaemia, Fatigue, Proteinuria, Abdominal Distension, Decreased Appetite, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Small Intestinal Obstruction, Hypophosphataemia, Diarrhoea, Alopecia, Dehydration, Neutropenia, Hypertension, Vascular Access Complication

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride and Irinotecan Hydrochloride
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Xeloda
    Dosage: 1000 mg/m2 twice daily for age below 65 years,750 mg/m2 twice daily for age above 65 years
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-10

Patient: female, weighing 58.6 kg (128.8 pounds)

Reactions: Confusional State, Blood Pressure Increased, Nausea, Pain, Sleep Talking, Protein Total Decreased, DRY Skin, Constipation, Death, Soliloquy, Diarrhoea, Hallucination

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Rectosigmoid Cancer
    Start date: 2011-12-27

Oxaliplatin
    Indication: Rectosigmoid Cancer
    Start date: 2011-12-27

Xeloda
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic
    Start date: 2011-12-27

Other drugs received by patient: Paxil; Promethazine; Atenolol; D5W .2ns; Spiriva; Combivent; Risperdal; Sodium Chloride; Decadron Phosphate; Aloxi; Aspirin



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-10

Patient: male

Reactions: Death, Nausea, Diarrhoea, Asthenia, Epistaxis

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer

Capecitabine
    Indication: Product Used FOR Unknown Indication
    Start date: 2008-08-28
    End date: 2008-09-19

Other drugs received by patient: Leucovorin Calcium; Fluorouracil; Irinotecan HCL; Oxaliplatin



Possible Avastin side effects in male

Reported by a consumer/non-health professional from China on 2012-08-09

Patient: male

Reactions: Diarrhoea, Alanine Aminotransferase Increased

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Vomiting, Nausea, Disease Progression, Gastritis, Neuropathy Peripheral, Diarrhoea, Neutropenia, Thrombocytopenia, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Avastin
    Dosage: 12 courses of bevacizumab, first line treatment
    Indication: Colon Cancer
    Start date: 2008-06-30
    End date: 2008-12-23

Avastin
    Dosage: 6 courses of bevacizumab
    Start date: 2009-02-02
    End date: 2009-05-18

Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Oxaliplatin



Possible Avastin side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-09

Patient: male, weighing 60.8 kg (133.8 pounds)

Reactions: Diarrhoea, Rectal Haemorrhage, Amnesia, Hypersomnia

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Dexamethasone; Dilantin



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-09

Patient: female

Reactions: Death, Diarrhoea, Alopecia, Asthenia, Epistaxis, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Start date: 2009-05-05
    End date: 2010-06-08

Avastin
    Start date: 2010-06-29
    End date: 2010-06-29

Avastin
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Capecitabine
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-01-23
    End date: 2012-03-18

Fluorouracil
    Indication: Product Used FOR Unknown Indication
    Start date: 2002-06-17
    End date: 2003-12-23

Fluorouracil
    Start date: 2009-05-05
    End date: 2010-06-08

Fluorouracil
    Start date: 2011-09-28
    End date: 2011-09-28

Fluorouracil
    Start date: 2011-08-11
    End date: 2011-09-14

Fluorouracil
    Start date: 2005-08-31
    End date: 2008-09-10

Irinotecan HCL
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-11
    End date: 2011-09-14

Leucovorin Calcium
    Start date: 2011-08-11
    End date: 2011-09-14

Leucovorin Calcium
    Start date: 2009-05-05
    End date: 2010-06-08

Leucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Leucovorin Calcium
    Start date: 2011-09-28
    End date: 2011-09-28

Leucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2002-06-17
    End date: 2003-12-23

Oxaliplatin
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-08-31
    End date: 2008-09-10

Oxaliplatin
    Start date: 2009-05-05
    End date: 2010-06-08



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-09

Patient: male

Reactions: Death, Diarrhoea, Rectal Haemorrhage, Asthenia, Epistaxis

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Irinotecan HCL



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-08

Patient: female

Reactions: Phlebitis, Diarrhoea, Asthenia, Disease Progression

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: with folferi; received 4 cycles
    Indication: Colon Cancer Metastatic
    Start date: 2008-11-18
    End date: 2009-07-30

Avastin
    Dosage: with folfox;
    Start date: 2009-10-08
    End date: 2009-12-18

Other drugs received by patient: Fluorouracil; Oxaliplatin; Leucovorin Calcium; Irinotecan Hydrochloride



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-08

Patient: female

Reactions: Diarrhoea, Nausea, Asthenia, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Avastin
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-06-18
    End date: 2009-12-28

Avastin
    Start date: 2010-01-18
    End date: 2010-05-03

Other drugs received by patient: Irinotecan HCL; Capecitabine; Oxaliplatin; Irinotecan HCL



Possible Avastin side effects in 78 year old male

Reported by a consumer/non-health professional from China on 2012-08-07

Patient: 78 year old male

Reactions: Productive Cough, Asthma, Aphasia, Bronchial Carcinoma, Rash Pruritic, Death, Off Label Use, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Stomatitis, Dyspnoea, Vomiting, Blood Urea Increased, Nausea, Diarrhoea, Insomnia, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Rectal Cancer Metastatic

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-07

Patient: female

Reactions: Diarrhoea, Neutropenia, Asthenia, Thrombocytopenia, Disease Progression

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Leucovorin Calcium; Fluorouracil; Irinotecan HCL



Possible Avastin side effects in 78 year old male

Reported by a consumer/non-health professional from China on 2012-08-06

Patient: 78 year old male

Reactions: Productive Cough, Asthma, Aphasia, Bronchial Carcinoma, Rash Pruritic, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Decreased Appetite, Epistaxis, Vomiting, Stomatitis, Dyspnoea, Blood Urea Increased, Nausea, Diarrhoea, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic

Tarceva
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-06

Patient: male

Reactions: Diarrhoea, Disease Progression

Drug(s) suspected as cause:
Avastin
    Start date: 2010-08-19
    End date: 2010-09-17

Avastin
    Indication: Colon Cancer
    Start date: 2010-03-23
    End date: 2010-05-06

Other drugs received by patient: Irinotecan HCL; Fluorouracil; Irinotecan HCL; Leucovorin Calcium; Fluorouracil; Leucovorin Calcium; Fluorouracil; Leucovorin Calcium; Fluorouracil; Leucovorin Calcium; Irinotecan HCL



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-08-06

Patient:

Reactions: Vomiting, Anaemia, Pulmonary Embolism, Febrile Neutropenia, Palmar-Plantar Erythrodysaesthesia Syndrome, Peripheral Sensory Neuropathy, Mucosal Inflammation, Diarrhoea, Proteinuria, Neutropenia, Leukopenia

Drug(s) suspected as cause:
Avastin
    Dosage: fluorouracil based regimen
    Indication: Colorectal Cancer Metastatic

Avastin
    Dosage: capecitabine-based regimen

Fluorouracil
    Dosage: on day 1

Fluorouracil
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride
    Dosage: dose: 150/180 mg/m2 on day 1
    Indication: Colorectal Cancer Metastatic

Leucovorin Calcium
    Dosage: on day 1
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: on day 1
    Indication: Colorectal Cancer Metastatic

Xeloda
    Indication: Colorectal Cancer Metastatic



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