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Avastin (Bevacizumab) - General Physical Health Deterioration - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with General Physical Health Deterioration (149)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) where reactions include general physical health deterioration. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 149   Next >>

Possible Avastin side effects in 41 year old male

Reported by a physician from Austria on 2012-08-27

Patient: 41 year old male

Reactions: Neoplasm Progression, General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Brain Neoplasm Malignant

Irinotecan Hydrochloride
    Indication: Brain Neoplasm Malignant



Possible Avastin side effects in female

Reported by a physician from Canada on 2012-08-24

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, General Physical Health Deterioration, Muscular Weakness, Disease Progression, Dizziness, Platelet Count Decreased, Vision Blurred

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Synthroid



Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-22

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Cisplatin
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Pemetrexed Disodium
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Potassium Chloride; Norfloxacin; Dolpasse



Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin



Possible Avastin side effects in male

Reported by a physician from Germany on 2012-08-20

Patient: male

Reactions: General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-20

Patient: male

Reactions: Death, General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Lung Adenocarcinoma
    Start date: 2010-08-18
    End date: 2010-08-18

Avastin
    Start date: 2010-09-08
    End date: 2010-09-08

Other drugs received by patient: Mucodyne; Omeprazole; Mobic; Paclitaxel; Carboplatin; Carboplatin; Paclitaxel; Hokunalin; Carboplatin; Paclitaxel



Possible Avastin side effects in 60 year old female

Reported by a physician from France on 2012-08-20

Patient: 60 year old female

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a health professional (non-physician/pharmacist) from Finland on 2012-08-17

Patient: male

Reactions: General Physical Health Deterioration, Disease Progression

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-16

Patient: female, weighing 79.0 kg (173.8 pounds)

Reactions: General Physical Health Deterioration, Bradycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer
    Start date: 2012-05-02

Doxorubicin HCL
    Dosage: last dose prior to sae: 9/may/2012
    Indication: Breast Cancer
    Start date: 2012-05-02

Carboplatin
    Dosage: last dose prior to sae: 9 may 2012
    Indication: Breast Cancer
    Start date: 2012-05-02

Paclitaxel
    Dosage: last dose prior to sae: 9/may/2012
    Indication: Breast Cancer
    Start date: 2012-05-02

Other drugs received by patient: Granisetron; Ranitidine HCL; Dexamethasone



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-16

Patient: female, weighing 52.0 kg (114.4 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer
    Start date: 2008-01-10
    End date: 2011-03-01

Gemzar
    Indication: Chemotherapy
    Start date: 2010-12-21
    End date: 2011-03-01



Possible Avastin side effects in 74 year old male

Reported by a physician from Germany on 2012-08-16

Patient: 74 year old male, weighing 74.9 kg (164.8 pounds)

Reactions: General Physical Health Deterioration, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 1125 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-25

Carboplatin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 460 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Paclitaxel
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 269 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Placebo
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-05

Other drugs received by patient: Ondansetron; Allopurinol; Atrovent; Laxans-Ratiopharm; Dexamethasone; Dexamethasone; Metoclopramide; Glycilax; Ondansetron; Calcicare; Pamidronate Disodium; Ranitidine HCL; Diclofenac; Albuterol Sulfate; Clemastine Fumarate; Enalapril Maleate; Pantoprazole



Possible Avastin side effects in female

Reported by a physician from Canada on 2012-08-15

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Vomiting, Nausea, General Physical Health Deterioration, Muscular Weakness, Disease Progression, Platelet Count Decreased, Vision Blurred, Dizziness

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Synthroid



Possible Avastin side effects in 58 year old female

Reported by a physician from Germany on 2012-08-13

Patient: 58 year old female, weighing 55.0 kg (121.0 pounds)

Reactions: General Physical Health Deterioration, Device Related Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: last dose prior to sae : 01/aug/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Paclitaxel
    Dosage: last dose prior to sae : 01/aug/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Avastin
    Dosage: last dose prior to sae : 01/aug/2012, dose interrupted on 24/july/2012
    Indication: Ovarian Cancer
    Start date: 2012-05-22

Other drugs received by patient: Ciprofloxacin



Possible Avastin side effects in 58 year old female

Reported by a physician from Germany on 2012-08-13

Patient: 58 year old female, weighing 55.0 kg (121.0 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: last dose prior to sae : 01/aug/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Avastin
    Dosage: last dose prior to sae : 01/aug/2012
    Indication: Ovarian Cancer
    Start date: 2012-05-22

Carboplatin
    Dosage: last dose prior to sae : 01/aug/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Other drugs received by patient: Ciprofloxacin



Possible Avastin side effects in male

Reported by a physician from Germany on 2012-08-13

Patient: male, weighing 59.0 kg (129.8 pounds)

Reactions: Haemorrhage, Hypotension, Dehydration, Circulatory Collapse, General Physical Health Deterioration, Acute Prerenal Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: date of last dose prior to sae: 12/jun/2012
    Indication: Rectal Cancer Metastatic
    Start date: 2012-03-27

Avastin
    Dosage: date of last dose prior to sae: 12/jun/2012
    Indication: Rectal Cancer Metastatic
    Start date: 2012-03-27

Leucovorin Calcium
    Dosage: date of last dose prior to sae: 12/jun/2012
    Indication: Rectal Cancer Metastatic
    Start date: 2012-03-27

Other drugs received by patient: Granisetron Hydrochloride



Possible Avastin side effects in 74 year old male

Reported by a physician from Germany on 2012-08-10

Patient: 74 year old male, weighing 74.9 kg (164.8 pounds)

Reactions: General Physical Health Deterioration, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 460 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Avastin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 1125 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-25

Placebo
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-05

Paclitaxel
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 269 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-09

Patient: female, weighing 80.0 kg (176.0 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: last dose prior to sae: 30/jul/2012
    Indication: Breast Cancer
    Start date: 2012-01-09

Xeloda
    Dosage: last dose prior to sae: 03/aug/2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-01-09

Avastin
    Dosage: last dose prior to sae: 23/jul/2012
    Indication: Breast Cancer
    Start date: 2012-01-09

Other drugs received by patient: Enoxaparin Sodium; Zofran; Digitoxin TAB; Tramagit; Dipyrone TAB; Selenase



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-08

Patient: female, weighing 57.0 kg (125.4 pounds)

Reactions: Fatigue, Dyspnoea, General Physical Health Deterioration, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: last dose prior to sae 18 jun 2012
    Indication: Breast Cancer
    Start date: 2012-04-30
    End date: 2012-05-21

Xeloda
    Dosage: last dose prior to sae 22 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-04-30
    End date: 2012-06-03

Avastin
    Dosage: last dose prior to sae 13/jun/2012
    Indication: Breast Cancer
    Start date: 2012-04-30

Other drugs received by patient: Furosemide; Amlodipine; Amitriptyline HCL; Novalgin



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-07

Patient: male

Reactions: Death, General Physical Health Deterioration, Disease Progression, Epistaxis

Adverse event resulted in: death

Drug(s) suspected as cause:
Oxaliplatin
    Dosage: line 3
    Start date: 2011-10-11
    End date: 2011-11-09

Avastin
    Dosage: line 3
    Indication: Colon Cancer
    Start date: 2011-10-11
    End date: 2011-11-09

Fluorouracil
    Dosage: line 1
    Indication: Colon Cancer
    Start date: 2011-04-13
    End date: 2011-06-29

Leucovorin Calcium
    Dosage: line 1
    Indication: Colon Cancer
    Start date: 2011-04-13
    End date: 2011-06-29

Leucovorin Calcium
    Dosage: line 2
    Start date: 2011-07-12
    End date: 2011-09-28

Leucovorin Calcium
    Dosage: line 3
    Start date: 2011-10-11
    End date: 2011-11-09

Oxaliplatin
    Dosage: line 2
    Indication: Colon Cancer
    Start date: 2011-07-12
    End date: 2011-09-28

Irinotecan HCL
    Dosage: line 1
    Indication: Colon Cancer
    Start date: 2011-04-13
    End date: 2011-06-29

Fluorouracil
    Dosage: line 2
    Start date: 2011-07-12
    End date: 2011-09-28

Fluorouracil
    Dosage: line 3
    Start date: 2011-10-11
    End date: 2011-11-09



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-03

Patient: female, weighing 92.5 kg (203.5 pounds)

Reactions: Vomiting, Nausea, General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2012-06-21

Avastin
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2012-06-21

Other drugs received by patient: Xgeva



Possible Avastin side effects in female

Reported by a physician from France on 2012-08-03

Patient: female

Reactions: General Physical Health Deterioration, Disease Progression

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Leucovorin Calcium; Fluorouracil; Oxaliplatin



Possible Avastin side effects in 61 year old female

Reported by a physician from France on 2012-08-02

Patient: 61 year old female

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in 74 year old male

Reported by a physician from Germany on 2012-08-01

Patient: 74 year old male, weighing 74.9 kg (164.8 pounds)

Reactions: General Physical Health Deterioration, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 269 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Carboplatin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 460 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Placebo
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-05

Avastin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 1125 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-25



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-01

Patient: female

Reactions: Neoplasm Malignant, General Physical Health Deterioration, Immobile

Drug(s) suspected as cause:
Avastin
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2007-11-01
    End date: 2008-04-01

Avastin
    Start date: 2010-03-01

Gemcitabine Hydrochloride
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2010-03-01
    End date: 2010-05-01

Carboplatin
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2010-03-01
    End date: 2010-05-01

Avastin

Other drugs received by patient: Vinorelbine; Actiq; Granisetron; Zometa; Metoclopramide; Fentanyl Citrate; Dexamethasone Sodium Phosphate; Diazepam; Cisplatin



Possible Avastin side effects in female

Reported by a physician from France on 2012-07-30

Patient: female

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in 74 year old

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-27

Patient: 74 year old , weighing 62.0 kg (136.4 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in 58 year old female

Reported by a physician from Germany on 2012-07-26

Patient: 58 year old female, weighing 55.0 kg (121.0 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: last dose prior to sae 03/jul/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Carboplatin
    Dosage: last dose prior to sae 03/jul/2012
    Indication: Ovarian Cancer
    Start date: 2012-04-30

Avastin
    Dosage: last dose prior to sae 03/jul/2012
    Indication: Ovarian Cancer
    Start date: 2012-05-22



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-07-24

Patient: female, weighing 92.5 kg (203.5 pounds)

Reactions: Vomiting, Nausea, General Physical Health Deterioration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2012-06-21

Avastin
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2012-06-21

Other drugs received by patient: Xgeva



Possible Avastin side effects in 74 year old male

Reported by a physician from Germany on 2012-07-23

Patient: 74 year old male, weighing 74.9 kg (164.8 pounds)

Reactions: General Physical Health Deterioration, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Placebo
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-05

Avastin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 1125 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-25

Paclitaxel
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 269 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04

Carboplatin
    Dosage: most recent dose received 06/jun/2012, last dose of drug received 460 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-04-04



Possible Avastin side effects in 65 year old female

Reported by a physician from Germany on 2012-07-23

Patient: 65 year old female, weighing 46.4 kg (102.1 pounds)

Reactions: Weight Decreased, Fistula, Nausea, Anaemia, General Physical Health Deterioration, Fatigue, Sepsis, Decreased Appetite, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Cancer
    Start date: 2012-03-21
    End date: 2012-04-18

Carboplatin
    Dosage: auc 5,
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Paclitaxel
    Dosage: last dose:15/may/2012
    Indication: Ovarian Cancer
    Start date: 2012-02-27
    End date: 2012-04-18

Avastin
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Carboplatin
    Dosage: auc 5, last dose:15/may/2012
    End date: 2012-06-10

Paclitaxel
    Dosage: last dose:15/may/2012
    End date: 2012-06-10

Other drugs received by patient: Novalgin; Pantoprazole; Zolpidem



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