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Avastin (Bevacizumab) - Hypertension - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypertension (209)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) where reactions include hypertension. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 209   Next >>

Possible Avastin side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-27

Patient:

Reactions: Electrocardiogram QT Prolonged, Proctitis, Rhabdomyolysis, Gastrointestinal Haemorrhage, Hyperbilirubinaemia, Hypokalaemia, Neuropathy Peripheral, Intestinal Perforation, Fatigue, Proteinuria, Thrombocytopenia, Azotaemia, Hypovolaemia, Blood Alkaline Phosphatase Increased, Fistula, Stomatitis, Hyperglycaemia, Hyponatraemia, Hyperlipidaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Neutropenia, Abscess, Vaginal Infection, Hypertension

Drug(s) suspected as cause:
Avastin
    Indication: Colorectal Cancer Metastatic

Everolimus
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-22

Patient: female, weighing 67.3 kg (148.1 pounds)

Reactions: Drug Dose Omission, Vomiting, Headache, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: 664 mg

Eloxatin
    Dosage: 0 mg

Fluorouracil
    Dosage: 7392 mg

Leucovorin Calcium
    Dosage: 1408 mg

Other drugs received by patient: ...



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient:

Reactions: Gastrointestinal Haemorrhage, Hyperbilirubinaemia, Anaemia, Alanine Aminotransferase Increased, Rash, Gastritis, Breast Cancer Metastatic, Diarrhoea, Ejection Fraction Decreased, Aspartate Aminotransferase Increased, Hypertension

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: every 2 weeks
    Indication: Breast Cancer Metastatic

Lapatinib
    Administration route: Oral
    Indication: Breast Cancer Metastatic



Possible Avastin side effects in

Reported by a consumer/non-health professional from Poland on 2012-08-20

Patient:

Reactions: Blood Disorder, Bone Marrow Failure, Hypertension

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15

Patient:

Reactions: Confusional State, Disseminated Intravascular Coagulation, Haemorrhage Intracranial, Headache, Device Related Infection, Left Ventricular Failure, Cerebral Ischaemia, Proteinuria, Haemorrhagic Stroke, Hypertension, Blood Creatinine Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer Metastatic

Fulvestrant
    Indication: Breast Cancer Metastatic



Possible Avastin side effects in

Reported by a consumer/non-health professional from Poland on 2012-08-15

Patient:

Reactions: Blood Disorder, Bone Marrow Failure, Hypertension

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-15

Patient: male, weighing 51.0 kg (112.2 pounds)

Reactions: Haemoptysis, Interstitial Lung Disease, Platelet Count Decreased, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2010-11-16
    End date: 2010-11-16

Avastin
    Start date: 2010-12-16
    End date: 2010-12-16

Avastin
    Start date: 2010-10-14
    End date: 2010-10-14

Avastin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Avastin
    Start date: 2010-09-14
    End date: 2010-09-14

Carboplatin
    Start date: 2010-09-14
    End date: 2010-09-14

Carboplatin
    Start date: 2010-12-16
    End date: 2010-12-16

Carboplatin
    Start date: 2010-11-16
    End date: 2010-11-16

Carboplatin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Carboplatin
    Start date: 2010-10-14
    End date: 2010-10-14

Paclitaxel
    Start date: 2010-09-14
    End date: 2010-09-14

Paclitaxel
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Paclitaxel
    Start date: 2010-10-14
    End date: 2010-10-14

Paclitaxel
    Start date: 2010-12-16
    End date: 2010-12-16

Paclitaxel
    Start date: 2010-11-16
    End date: 2010-11-16



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-13

Patient:

Reactions: Abdominal Pain, Blood Bilirubin Increased, Thrombosis, Anal Examination Abnormal, Hypokalaemia, Fatigue, Proteinuria, Abdominal Distension, Decreased Appetite, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Small Intestinal Obstruction, Hypophosphataemia, Diarrhoea, Alopecia, Dehydration, Neutropenia, Hypertension, Vascular Access Complication

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride and Irinotecan Hydrochloride
    Dosage: given on day 1
    Indication: Colorectal Cancer Metastatic

Xeloda
    Dosage: 1000 mg/m2 twice daily for age below 65 years,750 mg/m2 twice daily for age above 65 years
    Administration route: Oral
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-13

Patient:

Reactions: Fatigue, Drug Ineffective, Central Nervous System Haemorrhage, Pancreatitis, Neutropenia, Hypertension, Cerebral Ischaemia

Drug(s) suspected as cause:
Avastin
    Indication: Central Nervous System Neoplasm

Irinotecan Hydrochloride
    Indication: Central Nervous System Neoplasm



Possible Avastin side effects in female

Reported by a physician from United Kingdom on 2012-08-10

Patient: female, weighing 73.0 kg (160.6 pounds)

Reactions: Haematuria, Proteinuria, Oedema, Hypertension

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Gemcitabine Hydrochloride; Carboplatin



Possible Avastin side effects in female

Reported by a physician from United Kingdom on 2012-08-10

Patient: female, weighing 79.1 kg (174.0 pounds)

Reactions: Sepsis, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: last dose prior to sae was cycle 2 on 22/jun/2012
    Indication: Breast Cancer
    Start date: 2012-06-22

Docetaxel
    Dosage: last dose prior to sae was cycle 2 on 22/jun/2012.
    Indication: Breast Cancer
    Start date: 2012-06-22



Possible Avastin side effects in 66 year old female

Reported by a physician from Germany on 2012-08-09

Patient: 66 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Oedema DUE To Cardiac Disease, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Carboplatin
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Paclitaxel
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Placebo
    Indication: non-Small Cell Lung Cancer Recurrent

Other drugs received by patient: Bisoprolol Fumarate; Potassium Chloride; Dexamethasone; Oxazepam; Novalgin; Zofran; Zofran; Lasix; Tavor (Germany); Oxygen; Torsemide; Paroxetine; Dexamethasone; Dexamethasone; Ranitidine HCL; Ximovan; Kalium; Lasix; Ramipril; Optipect; Spironolactone; Torsemide; Ringer Solution; Levothyroxine Sodium; Torsemide; Pantoprazole; Clemastine Fumarate; Perenterol Forte; Kalium; Metoclopramide



Possible Avastin side effects in 72 year old female

Reported by a physician from United States on 2012-08-09

Patient: 72 year old female, weighing 71.6 kg (157.5 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Urinary Tract Infection, Hypoxia, Urinary Retention, Hypertension, Ascites

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-10

Blinded Everolimus
    Dosage: level one dose reduction. last dose 26 apr 2012

Blinded Everolimus
    Administration route: Oral
    Indication: Ovarian Epithelial Cancer
    Start date: 2012-01-10



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-09

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: Hypertensive Encephalopathy, Pneumonia, Hypertension, Convulsion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Granisetron; Decadron Phosphate; Kytril; Levoleucovorin Calcium; Decadron Phosphate; Fluorouracil; Oxaliplatin



Possible Avastin side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-08

Patient: male

Reactions: Neoplasm Recurrence, Neoplasm, Hypertension, Disease Progression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Glioblastoma
    Start date: 2008-09-18

Avastin
    Start date: 2010-12-16

Avastin
    Start date: 2010-11-24

Avastin
    Start date: 2010-07-29



Possible Avastin side effects in male

Reported by a physician from France on 2012-08-08

Patient: male

Reactions: Aphthous Stomatitis, Nausea, Asthenia, Hypertension, Disease Progression

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in 61 year old female

Reported by a physician from United States on 2012-08-08

Patient: 61 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Lipase Increased, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae: 11/jun/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2011-12-12

Blinded Everolimus
    Dosage: date of last dose prior to sae: 16/jun/2012
    Indication: Ovarian Epithelial Cancer
    Start date: 2011-12-12



Possible Avastin side effects in male

Reported by a physician from Portugal on 2012-08-07

Patient: male

Reactions: Peripheral Sensory Neuropathy, Hypertension, Metastases To Lung

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer
    Start date: 2010-04-01

Fluorouracil
    Indication: Colon Cancer
    Start date: 2010-04-01

Irinotecan HCL
    Indication: Colon Cancer
    Start date: 2010-04-01

Leucovorin Calcium
    Indication: Colon Cancer
    Start date: 2010-04-01

Oxaliplatin
    Indication: Colon Cancer
    Start date: 2012-01-01



Possible Avastin side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-06

Patient: male

Reactions: Neoplasm Recurrence, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Glioblastoma
    Start date: 2008-09-18

Avastin
    Start date: 2010-07-29

Avastin
    Start date: 2010-11-24

Avastin
    Start date: 2010-12-16



Possible Avastin side effects in female

Reported by a physician from Morocco on 2012-08-06

Patient: female

Reactions: Renal Failure, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in 58 year old male

Reported by a consumer/non-health professional from China on 2012-08-03

Patient: 58 year old male, weighing 60.0 kg (132.0 pounds)

Reactions: Jaundice, Blood Bilirubin Increased, Colorectal Cancer Metastatic, Hypertension, Ascites

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: strength form was 100mg/4ml
    Indication: Colorectal Cancer
    Start date: 2011-06-24
    End date: 2011-08-15

Xeloda
    Indication: Colorectal Cancer

Other drugs received by patient: Chemotherapy NOS



Possible Avastin side effects in female

Reported by a consumer/non-health professional from Venezuela on 2012-08-02

Patient: female, weighing 47.0 kg (103.4 pounds)

Reactions: Blood Glucose Decreased, Syncope, Hypertension

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Cisplatin; Pemetrexed



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-07-30

Patient:

Reactions: Haemorrhage, Pseudoendophthalmitis, Cardiac Disorder, Death, Benign Neoplasm, Myocardial Infarction, Arterial Thrombosis, Vomiting, Pneumonia, Nausea, Urinary Tract Infection, Hernia, Cerebrovascular Accident, Endophthalmitis, Neoplasm Malignant, Gastrointestinal Disorder, Venous Thrombosis, Nervous System Disorder, Hypertension, Angiopathy, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-07-27

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Pneumonia, Nasopharyngitis, Rash, Eczema, Colonic Polyp, Interstitial Lung Disease, Hypertension, Neutrophil Count Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Ampicillin Sodium
    Indication: Interstitial Lung Disease
    Start date: 2012-05-02
    End date: 2012-05-09

Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2011-12-28

Avastin
    Start date: 2012-03-15
    End date: 2012-03-15

Avastin
    Start date: 2012-02-01
    End date: 2012-02-01

Carboplatin
    Start date: 2012-02-01

Carboplatin
    Start date: 2012-03-15
    End date: 2012-03-15

Carboplatin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28

Paclitaxel
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2012-01-01

Paclitaxel
    Start date: 2012-02-01
    End date: 2012-01-01

Paclitaxel
    Start date: 2012-03-15
    End date: 2012-04-12

Other drugs received by patient: Dexamethasone Sodium Phosphate; Rebamipide; Loxoprofen Sodium; Zofran; Restamin; Diclofenac Sodium; Sennoside; Brotizolam; Vitamedin (Japan); Gaster (Japan); Granisetron Hydrochloride



Possible Avastin side effects in male

Reported by a pharmacist from Japan on 2012-07-25

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: Hypertensive Encephalopathy, Pneumonia, Hypertension, Convulsion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Fluorouracil; Oxaliplatin; Levoleucovorin Calcium; Decadron; Granisetron; Kytril; Decadron; Micardis



Possible Avastin side effects in female

Reported by a physician from Austria on 2012-07-25

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Neurological Symptom, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Docetaxel; Vinorelbine



Possible Avastin side effects in

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-25

Patient:

Reactions: Gastrointestinal Perforation, Embolism, Hypertension

Drug(s) suspected as cause:
Avastin
    Dosage: day 1
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: day 1
    Indication: Colorectal Cancer Metastatic

Xeloda
    Dosage: day 1-14
    Indication: Colorectal Cancer Metastatic



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-07-23

Patient: male, weighing 47.0 kg (103.4 pounds)

Reactions: Interstitial Lung Disease, Hypertension

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic
    Start date: 2011-11-10

Xeloda
    Dosage: it is two administering weekly holiday medicine for two weeks.
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2011-11-10

Other drugs received by patient: Maglax



Possible Avastin side effects in

Reported by a physician from Spain on 2012-07-23

Patient:

Reactions: Haemorrhage, Unevaluable Event, Hypertension

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in female

Reported by a physician from United Kingdom on 2012-07-23

Patient: female, weighing 73.0 kg (160.6 pounds)

Reactions: Proteinuria, Haematuria, Oedema, Hypertension

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Gemcitabine; Carboplatin



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