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Avastin (Bevacizumab) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (302)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Avastin (Bevacizumab) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 302   Next >>

Possible Avastin side effects in female

Reported by a physician from Canada on 2012-08-27

Patient: female, weighing 86.0 kg (189.2 pounds)

Reactions: Angina Unstable, Proteinuria

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Product Used FOR Unknown Indication

Lucentis
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Metoprolol Tartrate; Risedronate Sodium; Diovan; Lansoprazole; Novolin 70 / 30; Plavix; Lipitor; Amlodipine; Gabapentin; Calcium Carbonate



Possible Avastin side effects in male

Reported by a physician from Lebanon on 2012-08-23

Patient: male, weighing 74.5 kg (163.9 pounds)

Reactions: Abscess Neck, Pharyngeal Fistula, Disseminated Intravascular Coagulation, Vascular Pseudoaneurysm, Pharyngeal Ulceration, Septic Shock, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Oxaliplatin; Bisoprolol Fumarate



Possible Avastin side effects in 52 year old female

Reported by a consumer/non-health professional from France on 2012-08-22

Patient: 52 year old female

Reactions: Chest Wall Necrosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: 1 df = 25mg/ml, concentrate for solution for infusion
    Start date: 2012-02-01
    End date: 2012-06-06

Taxol
    Start date: 2012-02-01
    End date: 2012-06-06



Possible Avastin side effects in 65 year old female

Reported by a physician from Switzerland on 2012-08-21

Patient: 65 year old female

Reactions: Vomiting, Diarrhoea, Anaemia, General Physical Health Deterioration, Hypokalaemia

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Carboplatin
    Indication: Adenocarcinoma
    Start date: 2011-02-14

Cisplatin
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Pemetrexed Disodium
    Dosage: date of last dose prior to sae: 20/jan/2012
    Indication: Adenocarcinoma
    Start date: 2011-12-30

Other drugs received by patient: Crestor; Dolpasse; Potassium Chloride; Norfloxacin



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Productive Cough, Aphasia, Bronchial Carcinoma, Rash Pruritic, Poor Quality Sleep, Death, Incontinence, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Dyspnoea, Blood Urea Increased, Stomatitis, Vomiting, Nausea, Rhinorrhoea, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic

Tarceva
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in female

Reported by a physician from Germany on 2012-08-20

Patient: female, weighing 52.0 kg (114.4 pounds)

Reactions: Syncope, Supraventricular Tachycardia, Dehydration, Pulmonary Oedema

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: 1 x 90 minutes. last dose prior to sae was taken on 11/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-07-11

Irinotecan Hydrochloride
    Dosage: 1 x 2 hours
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride
    Start date: 2012-08-01

Xeloda
    Dosage: 2 tablets in the morning and 2 tablets in the evening.
    Administration route: Oral
    Start date: 2012-08-01

Xeloda
    Dosage: 3 tablets in the morning and 2 tablets in the evening. last dose prior to sae was taken on 24/jul/20
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-07-11



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-20

Patient: male

Reactions: Pneumonia Aspiration, Haemoptysis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Lung Adenocarcinoma

Carboplatin
    Indication: Lung Adenocarcinoma

Pemetrexed
    Indication: Lung Adenocarcinoma



Possible Avastin side effects in male

Reported by a pharmacist from Japan on 2012-08-20

Patient: male, weighing 63.0 kg (138.6 pounds)

Reactions: Back Pain, Dyspnoea, Haemoptysis, Disseminated Intravascular Coagulation, Cold Sweat

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: 11 course
    Indication: Large Intestine Carcinoma
    Start date: 2011-12-06
    End date: 2012-04-10

Levoleucovorin Calcium
    Indication: Large Intestine Carcinoma
    Start date: 2011-12-06
    End date: 2012-04-10

Oxaliplatin
    Dosage: uncertain dosage and 11 course
    Indication: Large Intestine Carcinoma
    Start date: 2011-12-06
    End date: 2012-04-10

Other drugs received by patient: Fluorouracil; Levoleucovorin Calcium; Levoleucovorin Calcium; Granisetron; Dexamethasone Sodium Phosphate; Fluorouracil; Fluorouracil; Fluorouracil



Possible Avastin side effects in 79 year old male

Reported by a consumer/non-health professional from China on 2012-08-20

Patient: 79 year old male

Reactions: Asthma, Productive Cough, Urinary Incontinence, Bronchial Carcinoma, Aphasia, Rash Pruritic, Off Label Use, Poor Quality Sleep, Death, Oedema Peripheral, Blood Creatinine Increased, Epistaxis, Decreased Appetite, Emphysema, Stomatitis, Vomiting, Pneumonia, Dyspnoea, Blood Urea Increased, Nausea, Rhinorrhoea, Rash, Diarrhoea, Cerebral Infarction, Depressed Level of Consciousness, Metastases To Bone, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: unk
    Indication: Rectal Cancer Metastatic

Tarceva
    Dosage: 150 mg, uid/qd
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-09

Xeloda
    Dosage: 1.5 df, bid for 2 weeks followed by 7 day rest period
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    End date: 2012-02-23



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-17

Patient: male, weighing 40.0 kg (88.0 pounds)

Reactions: Gastrointestinal Perforation, Wound Dehiscence, Wound Infection, Peritonitis, Disease Progression

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Indication: Colon Cancer Metastatic
    Start date: 2012-03-14
    End date: 2012-04-25

Fluorouracil
    Start date: 2012-02-29
    End date: 2012-04-27

Fluorouracil
    Dosage: dosage is uncertain.
    Indication: Colon Cancer Metastatic
    Start date: 2012-02-29
    End date: 2012-04-25

Oxaliplatin
    Indication: Colon Cancer Metastatic
    Start date: 2012-02-29
    End date: 2012-04-10

Other drugs received by patient: Loxonin; Emend; Levoleucovorin Calcium; Levoleucovorin Calcium; Emend; Ferrous Citrate; Maglax; Mucosta



Possible Avastin side effects in female

Reported by a physician from Japan on 2012-08-17

Patient: female, weighing 36.0 kg (79.2 pounds)

Reactions: Cardio-Respiratory Arrest, Pneumonia, Haemoptysis, Obstructive Airways Disorder

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Prochlorperazine; Morphine Sulfate; Alimta; Carboplatin



Possible Avastin side effects in male

Reported by a physician from Austria on 2012-08-17

Patient: male, weighing 99.0 kg (217.8 pounds)

Reactions: Renal Failure, Sepsis, Diarrhoea Haemorrhagic, Leukopenia

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Neoplasm
    Start date: 2012-07-04

Capecitabine
    Administration route: Oral
    Indication: Rectal Neoplasm
    Start date: 2012-07-04
    End date: 2012-07-15

Other drugs received by patient: Oxaliplatin



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-17

Patient: female, weighing 65.3 kg (143.7 pounds)

Reactions: Neutropenic Colitis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of most recent dose prior to sae: 20/mar/2012
    Indication: Colon Cancer
    Start date: 2012-01-31

Fluorouracil

Fluorouracil
    Dosage: date of most recent dose prior to sae: 20/mar/2012
    Indication: Colon Cancer
    Start date: 2012-01-31

Folinic Acid
    Dosage: date of most recent dose prior to sae: 20/mar/2012
    Indication: Colon Cancer
    Start date: 2012-01-31

Oxaliplatin
    Dosage: date of most recent dose prior to sae: 20/mar/2012
    Indication: Colon Cancer
    Start date: 2012-01-31



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-15

Patient: male, weighing 51.0 kg (112.2 pounds)

Reactions: Haemoptysis, Interstitial Lung Disease, Platelet Count Decreased, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2010-11-16
    End date: 2010-11-16

Avastin
    Start date: 2010-12-16
    End date: 2010-12-16

Avastin
    Start date: 2010-10-14
    End date: 2010-10-14

Avastin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Avastin
    Start date: 2010-09-14
    End date: 2010-09-14

Carboplatin
    Start date: 2010-09-14
    End date: 2010-09-14

Carboplatin
    Start date: 2010-12-16
    End date: 2010-12-16

Carboplatin
    Start date: 2010-11-16
    End date: 2010-11-16

Carboplatin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Carboplatin
    Start date: 2010-10-14
    End date: 2010-10-14

Paclitaxel
    Start date: 2010-09-14
    End date: 2010-09-14

Paclitaxel
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Paclitaxel
    Start date: 2010-10-14
    End date: 2010-10-14

Paclitaxel
    Start date: 2010-12-16
    End date: 2010-12-16

Paclitaxel
    Start date: 2010-11-16
    End date: 2010-11-16



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-15

Patient: female, weighing 114.7 kg (252.3 pounds)

Reactions: Cerebrovascular Accident, Acute Respiratory Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Blinded Onartuzumab
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Fluorouracil
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Leucovorin Calcium
    Dosage: 456, date of last dose prior to sae 27/jun/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Oxaliplatin
    Dosage: date of last dose prior to sae 13/jun/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Other drugs received by patient: Premarin; Compazine; Losartan Potassium and Hydrochlorothiazide; Tebs EYE Formula FOR Macula Support Smokers Formula; Aspirin; Fibercon; Ativan; Lomotil; Zofran; Magnesium; Crestor; Neupogen



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-14

Patient: male, weighing 68.0 kg (149.6 pounds)

Reactions: Intestinal Perforation, Malignant Ascites, Malignant Pleural Effusion, Disseminated Intravascular Coagulation, Septic Shock, Disease Progression, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: eight times
    Start date: 2011-11-14
    End date: 2012-04-09

Avastin
    Dosage: 26 times
    Start date: 2010-08-30
    End date: 2011-09-12

Avastin
    Dosage: nine times
    Indication: Rectal Cancer Recurrent
    Start date: 2009-08-17

Avastin
    Dosage: eight times
    End date: 2010-04-26

Avastin
    Dosage: eight times
    Start date: 2010-05-10
    End date: 2010-08-16

Other drugs received by patient: Oxaliplatin; Fluorouracil; Fluorouracil; Irinotecan HCL; TS-1; Levoleucovorin Calcium; Levoleucovorin Calcium; Fluorouracil; Fluorouracil; Fluorouracil; Levoleucovorin Calcium; Oxaliplatin; Fluorouracil



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-14

Patient: female, weighing 68.1 kg (149.8 pounds)

Reactions: Lung Neoplasm Malignant, Lower Gastrointestinal Haemorrhage, Cardiac Arrest

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Alimta; Cisplatin



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-14

Patient: female, weighing 114.7 kg (252.3 pounds)

Reactions: Acute Respiratory Failure, Cerebrovascular Accident

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Blinded Onartuzumab
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Fluorouracil
    Dosage: date of last dose prior to sae 30/jul/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Leucovorin Calcium
    Dosage: 456, date of last dose prior to sae 27/jun/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Oxaliplatin
    Dosage: date of last dose prior to sae 13/jun/2012
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-05-30

Other drugs received by patient: Lomotil; Premarin; Compazine; Zofran; Aspirin; Fibercon; Losartan Potassium and Hydrochlorothiazide; Neupogen; Ativan; Crestor; Tebs EYE Formula FOR Macula Support Smokers Formula



Possible Avastin side effects in 50 year old female

Reported by a physician from Japan on 2012-08-13

Patient: 50 year old female, weighing 48.0 kg (105.6 pounds)

Reactions: Renal Impairment, Disease Progression

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-01

Decadron Phosphate
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-06-01
    End date: 2012-06-01

Decadron Phosphate
    Administration route: Oral
    Start date: 2012-06-01
    End date: 2012-06-03

Oxaliplatin
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-01

Xeloda
    Administration route: Oral
    Indication: Rectal Cancer Metastatic
    Start date: 2012-06-01
    End date: 2012-06-06

Other drugs received by patient: Oxycontin; Aldactone; BIO-Three; Mucosta; Lasix; Prochlorperazine; Magmitt; Loxonin



Possible Avastin side effects in 19 year old female

Reported by a consumer/non-health professional from Ecuador on 2012-08-13

Patient: 19 year old female

Reactions: Vomiting, Dyspnoea, Aphasia, Pyrexia, Asthenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-13

Patient: male, weighing 65.0 kg (143.0 pounds)

Reactions: Intestinal Ischaemia, Disseminated Intravascular Coagulation, Shock

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-06-19
    End date: 2012-07-18

Carboplatin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-06-19
    End date: 2012-07-18

Paclitaxel
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-06-19
    End date: 2012-07-18

Other drugs received by patient: Decadron Phosphate; Aloxi



Possible Avastin side effects in 52 year old female

Reported by a physician from France on 2012-08-10

Patient: 52 year old female

Reactions: Chest Wall Necrosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-01
    End date: 2012-06-06

Taxol
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-01
    End date: 2012-06-06



Possible Avastin side effects in male

Reported by a consumer/non-health professional from Australia on 2012-08-10

Patient: male

Reactions: Grand MAL Convulsion, Brain Oedema

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin



Possible Avastin side effects in female

Reported by a physician from United States on 2012-08-08

Patient: female, weighing 60.8 kg (133.8 pounds)

Reactions: Back Pain, Swelling Face, Pyrexia, Rash

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Fluorouracil; Oxaliplatin



Possible Avastin side effects in female

Reported by a physician from Japan on 2012-08-08

Patient: female

Reactions: Disseminated Intravascular Coagulation, Hepatic Failure, Duodenal Perforation

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Levofloxacin; Paclitaxel; Mucosta; Loxonin; Lyrica; Allopurinol; Kolantyl; Juvela N; Neurovitan (Ukraine)



Possible Avastin side effects in female

Reported by a physician from Japan on 2012-08-08

Patient: female, weighing 50.0 kg (110.0 pounds)

Reactions: Breast Cancer Metastatic, Nausea, Anaemia, Pain, Pulmonary Infarction, Tumour Haemorrhage

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Mucosta; Paclitaxel; Loxonin; Pursennid



Possible Avastin side effects in male

Reported by a physician from Italy on 2012-08-07

Patient: male

Reactions: Myocardial Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Avastin
    Dosage: 375 milligram daily;
    Indication: Colon Cancer Metastatic
    Start date: 2012-01-24
    End date: 2012-06-01

Fluorouracil
    Dosage: 5376 milligram daily;
    Indication: Colon Cancer Metastatic
    Start date: 2012-01-24
    End date: 2012-06-01

Oxaliplatin
    Dosage: 163 milligram daily;
    Indication: Colon Cancer Metastatic
    Start date: 2012-01-24
    End date: 2012-06-01



Possible Avastin side effects in female

Reported by a physician from China on 2012-08-06

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Death, Cardiac Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: most recent dose prior to the event: 21/mar/2012, 840 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05

Carboplatin
    Dosage: most recent dose prior to event: 21/mar/2012, 739 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05

Paclitaxel
    Dosage: most recent dose prior to event: 21/mar/2012, 265 mg
    Indication: non-Small Cell Lung Cancer
    Start date: 2012-01-05



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-06

Patient: male

Reactions: Pneumonia, Vomiting, Oesophagobronchial Fistula, Bacteraemia, Lung Infection, Pneumothorax, Oesophageal Haemorrhage, Delirium

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Avastin

Other drugs received by patient: Alimta; Carboplatin; Aspirin



Possible Avastin side effects in male

Reported by a physician from Japan on 2012-08-03

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Idiopathic Pulmonary Fibrosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alimta
    Start date: 2012-02-14
    End date: 2012-02-14

Alimta
    Dosage: dosage is uncertain.
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2012-01-24
    End date: 2012-01-24

Avastin
    Dosage: dosage is uncertain.
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2012-01-24
    End date: 2012-02-14

Other drugs received by patient: Hokunalin; Decadron Phosphate; Aloxi; Mucosta; Oxycontin; Mucosolvan; Loxonin; Urso 250



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