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Benadryl (Diphenhydramine) - Hypersensitivity - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypersensitivity (27)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Benadryl (Diphenhydramine) where reactions include hypersensitivity. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Benadryl side effects in 21 year old female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: 21 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: Hypersensitivity

Drug(s) suspected as cause:
Demerol
    Dosage: unk
    Indication: Pain

Hydrocodone Bitartrate
    Dosage: unk
    Indication: Pain
    Start date: 2011-11-01

Cortisone Acetate
    Dosage: unk
    Indication: Pain
    Start date: 1988-01-01

Darvocet-N 50
    Dosage: unk
    Indication: Pain
    Start date: 2008-01-01

Morphine Sulfate
    Dosage: unk
    Indication: Pain
    Start date: 1984-01-01

Benadryl
    Dosage: unk
    Start date: 1988-01-01



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-31

Patient: female, weighing 83.9 kg (184.6 pounds)

Reactions: Procedural Pain, Hypersensitivity, Contusion, Fall

Drug(s) suspected as cause:
Skelaxin
    Administration route: Oral
    Indication: Muscle Relaxant Therapy
    Start date: 2012-06-11
    End date: 2012-06-01

Benadryl
    Administration route: Oral
    Indication: Urticaria
    Start date: 2012-06-20
    End date: 2012-06-01

Stelara
    Indication: Psoriasis
    Start date: 2012-03-01

Hydrocodone
    Administration route: Oral
    Indication: Procedural Pain
    Start date: 2012-06-11
    End date: 2012-06-01

Hydroxyzine HCL
    Administration route: Oral
    Indication: Urticaria
    Start date: 2012-06-01

Tramadol Hydrochloride
    Administration route: Oral
    Indication: Procedural Pain
    Start date: 2012-06-11

Corticosteroids
    Dosage: given once
    Indication: Urticaria
    Start date: 2012-06-01
    End date: 2012-06-01



Possible Benadryl side effects in male

Reported by a physician from United States on 2012-07-24

Patient: male

Reactions: Hypersensitivity, Pain, Eye Oedema

Drug(s) suspected as cause:
Benadryl
    Dosage: unk

Bicillin L-A
    Dosage: 1.2 mg, unk
    Indication: Lyme Disease



Possible Benadryl side effects in female

Reported by a physician from United States on 2012-07-12

Patient: female, weighing 98.9 kg (217.5 pounds)

Reactions: Hypersensitivity, Hypertension, Infusion Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Administration route: Oral
    Indication: Premedication
    Start date: 2012-03-07
    End date: 2012-03-07

Acetaminophen
    Administration route: Oral

Benadryl
    Administration route: Oral
    Indication: Premedication
    Start date: 2012-03-07
    End date: 2012-03-07

Remicade
    Indication: Psoriatic Arthropathy
    Start date: 2011-06-29

Remicade
    Start date: 2012-03-06
    End date: 2012-03-08

Other drugs received by patient: Hydroxychloroquine Sulfate; Hydrochlorothiazide; Calcium with Vitamin D; Asacol; Quinapril; Tramadol HCL; Flexeril



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-11

Patient: female, weighing 83.9 kg (184.6 pounds)

Reactions: Procedural Pain, Contusion, Hypersensitivity, Fall

Drug(s) suspected as cause:
Benadryl
    Administration route: Oral
    Indication: Urticaria
    Start date: 2012-06-20
    End date: 2012-06-01

Stelara
    Indication: Psoriasis
    Start date: 2012-03-01

Hydrocodone Bitartrate
    Administration route: Oral
    Indication: Procedural Pain
    Start date: 2012-06-11
    End date: 2012-06-01

Hydroxyzine HCL
    Administration route: Oral
    Indication: Urticaria
    Start date: 2012-06-01

Tramadol HCL
    Administration route: Oral
    Indication: Procedural Pain
    Start date: 2012-06-11

Corticosteroids
    Dosage: given once
    Indication: Urticaria
    Start date: 2012-06-01
    End date: 2012-06-01

Skelaxin
    Administration route: Oral
    Indication: Muscle Relaxant Therapy
    Start date: 2012-06-11
    End date: 2012-06-01



Possible Benadryl side effects in 34 year old female

Reported by a physician from United States on 2012-05-30

Patient: 34 year old female

Reactions: Blood Pressure Increased, Hypersensitivity, Muscle Spasms

Drug(s) suspected as cause:
Benadryl
    Indication: Migraine

Phenergan
    Indication: Migraine

Toradol
    Indication: Migraine

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Tylenol
    Indication: Migraine

Other drugs received by patient: Triamcinolone; Clonazepam; Unspecified Medication; Halcinonide; Proton Pump Inhibitor; Diphenhydramine HCL



Possible Benadryl side effects in 34 year old female

Reported by a consumer/non-health professional from United States on 2012-05-16

Patient: 34 year old female

Reactions: Off Label Use, Blood Pressure Increased, Hypersensitivity, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenergan
    Indication: Migraine
    Start date: 2012-03-19

Tylenol (Caplet)
    Administration route: Oral

Benadryl
    Indication: Injection Related Reaction
    Start date: 2012-03-19

Unknown Medication
    Indication: Migraine
    Start date: 2012-03-19

Toradol
    Indication: Migraine
    Start date: 2012-03-19

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Tylenol (Caplet)
    Administration route: Oral
    Indication: Migraine
    Start date: 2012-03-19

Other drugs received by patient: Halcinonide; Humira; Clonazepam; Protonix; Triamcinolone; Triamcinolone Acetonide; Diphenhydramine Hydrochloride



Possible Benadryl side effects in 35 year old female

Reported by a physician from United States on 2012-05-09

Patient: 35 year old female

Reactions: Blood Pressure Increased, Migraine, Hypersensitivity, Injection Site Pain, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenergan
    Indication: Migraine

Acetaminophen
    Indication: Migraine

Benadryl
    Indication: Migraine

Humira

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Toradol
    Indication: Migraine

Other drugs received by patient: Triamcinolone; Vistaril; Allergy Shots; Klonopin; Acetonide; Halog; Protonix



Possible Benadryl side effects in 34 year old female

Reported by a physician from United States on 2012-04-30

Patient: 34 year old female

Reactions: Migraine, Blood Pressure Increased, Hypersensitivity, Injection Site Pain, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Toradol
    Indication: Migraine

Benadryl
    Indication: Migraine

Tylenol (Caplet)
    Indication: Migraine

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Phenergan
    Indication: Migraine

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Other drugs received by patient: Triamcinolone; Protonics; Acetonide; Allergy; Klonopin; Halog



Possible Benadryl side effects in 47 year old female

Reported by a consumer/non-health professional from Canada on 2012-04-30

Patient: 47 year old female, weighing 81.7 kg (179.6 pounds)

Reactions: Hypersensitivity, Cardiovascular Insufficiency, Application Site Pain, Application Site Dryness

Drug(s) suspected as cause:
Benadryl



Possible Benadryl side effects in 34 year old female

Reported by a physician from United States on 2012-04-12

Patient: 34 year old female

Reactions: Blood Pressure Increased, Migraine, Hypersensitivity, Injection Site Pain, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenergan HCL
    Indication: Migraine

Toradol
    Indication: Migraine

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Tylenol (Caplet)
    Indication: Migraine

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Benadryl
    Indication: Migraine

Other drugs received by patient: Halog; Allergy; Triamcinolone; Protonics; Klonopin; Acetonide



Possible Benadryl side effects in 34 year old female

Reported by a consumer/non-health professional from United States on 2012-03-30

Patient: 34 year old female

Reactions: Migraine, Blood Pressure Increased, Hypersensitivity, Injection Site Pain, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Toradol
    Indication: Migraine

Benadryl
    Indication: Migraine

Tylenol
    Indication: Migraine

Phenergan HCL
    Indication: Migraine

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Other drugs received by patient: Triamcinolone; Acetonide; Halog; Protonics; Klonopin; Allergy



Possible Benadryl side effects in 34 year old female

Reported by a consumer/non-health professional from United States on 2012-03-30

Patient: 34 year old female

Reactions: Blood Pressure Increased, Migraine, Hypersensitivity, Injection Site Pain, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Toradol
    Indication: Migraine

Humira
    Indication: Psoriasis
    Start date: 2012-02-15

Benadryl
    Indication: Migraine

Imitrex
    Indication: Migraine
    Start date: 2012-03-19

Tylenol
    Indication: Migraine

Phenergan HCL
    Indication: Migraine

Other drugs received by patient: Klonopin; Protonics; Allergy; Acetonide; Triamcinolone; Halog



Possible Benadryl side effects in female

Reported by a physician from United States on 2012-03-29

Patient: female, weighing 87.5 kg (192.6 pounds)

Reactions: Myalgia, Pruritus, Hypersensitivity, Drug Ineffective, Arthralgia, Pain, Skin Burning Sensation, Hypersomnia

Drug(s) suspected as cause:
Benadryl
    Dosage: 25 mg, unk
    Administration route: Oral

Codeine Sulfate
    Dosage: unk

Lyrica
    Dosage: 150 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2011-08-01
    End date: 2012-02-01

Hydrocodone Bitartrate
    Dosage: unk

Ultram ER
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia

Other drugs received by patient: Levothyroxine; Bisoprolol Fumarate and Hydrochlorothiazide; Aldactone; Metformin; Glimepiride



Possible Benadryl side effects in 47 year old female

Reported by a consumer/non-health professional from Canada on 2012-03-27

Patient: 47 year old female, weighing 81.7 kg (179.6 pounds)

Reactions: Hypersensitivity, Cardiovascular Insufficiency, Application Site Dryness, Application Site Pain

Drug(s) suspected as cause:
Benadryl



Possible Benadryl side effects in 41 year old female

Reported by a consumer/non-health professional from United States on 2012-03-20

Patient: 41 year old female, weighing 49.9 kg (109.8 pounds)

Reactions: Anxiety, Hypersensitivity

Drug(s) suspected as cause:
Benadryl
    Administration route: Oral

Benadryl
    Dosage: ^two caplets one time only^
    Administration route: Oral
    Indication: Hypersensitivity
    Start date: 2012-01-01
    End date: 2012-01-01

Other drugs received by patient: Allegra; Pepcid



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-06

Patient: female, weighing 87.5 kg (192.6 pounds)

Reactions: Myalgia, Pruritus, Hypersensitivity, Drug Ineffective, Arthralgia, Pain, Skin Burning Sensation, Hypersomnia

Drug(s) suspected as cause:
Hydrocodone Bitartrate
    Dosage: unk

Benadryl
    Dosage: 25 mg, unk
    Administration route: Oral

Codeine Sulfate
    Dosage: unk

Lyrica
    Dosage: 150 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2011-08-01
    End date: 2012-02-01

Ultram ER
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia

Other drugs received by patient: Levothyroxine; Aldactone; Metformin; Glimepiride; Bisoprolol Fumarate and Hydrochlorothiazide



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-02

Patient: female, weighing 87.5 kg (192.6 pounds)

Reactions: Myalgia, Pruritus, Hypersensitivity, Drug Ineffective, Arthralgia, Pain, Skin Burning Sensation, Hypersomnia

Drug(s) suspected as cause:
Benadryl
    Dosage: 25 mg, unk
    Administration route: Oral

Ultram ER
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia

Lyrica
    Dosage: 150 mg, 2x/day
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2011-08-01
    End date: 2012-02-01

Codeine Sulfate
    Dosage: unk

Hydrocodone Bitartrate
    Dosage: unk

Other drugs received by patient: Bisoprolol Fumarate and Hydrochlorothiazide; Metformin; Glimepiride; Levothyroxine; Aldactone



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-02

Patient: female

Reactions: Respiratory Disorder, Hypersensitivity, Swelling

Drug(s) suspected as cause:
Benadryl
    Dosage: daily dose text: unspecified
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Benadryl
    Administration route: Oral

Other drugs received by patient: Oral Contraceptive Unspecified



Possible Benadryl side effects in female

Reported by a physician from United States on 2012-03-02

Patient: female

Reactions: Hypersensitivity, Respiratory Disorder, Dyspnoea, Swelling

Drug(s) suspected as cause:
Benadryl
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Acetaminophen
    Administration route: Oral

Benadryl
    Administration route: Oral

Acetaminophen
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Oral Contraceptives (Unspecified)



Possible Benadryl side effects in 7 year old male

Reported by a consumer/non-health professional from United States on 2012-02-22

Patient: 7 year old male

Reactions: Product Quality Issue, Chest Discomfort, Hypersensitivity, Angioedema, Nausea, Wheezing, Urticaria, Impaired Work Ability, Pyrexia, Rash, Headache, Pallor, Malaise, Cough

Drug(s) suspected as cause:
Acetaminophen

Junior Strength Motrin

Benadryl
    Indication: Product Used FOR Unknown Indication

Junior Strength Motrin
    Indication: Ill-Defined Disorder

Acetaminophen
    Indication: Product Used FOR Unknown Indication

Benadryl



Possible Benadryl side effects in 7 year old male

Reported by a consumer/non-health professional from United States on 2012-02-21

Patient: 7 year old male

Reactions: Hypersensitivity, Chest Discomfort, Angioedema, Nausea, Impaired Work Ability, Urticaria, Wheezing, Headache, Pyrexia, Rash, Pallor, Malaise, Cough

Drug(s) suspected as cause:
Benadryl
    Dosage: daily dose text: unspecified
    Indication: Product Used FOR Unknown Indication

Benadryl

Motrin
    Dosage: daily dose text: unspecified
    Indication: Product Used FOR Unknown Indication

Acetaminophen
    Dosage: daily dose text: unspecified
    Indication: Product Used FOR Unknown Indication



Possible Benadryl side effects in female

Reported by a consumer/non-health professional from United States on 2012-01-20

Patient: female, weighing 93.0 kg (204.5 pounds)

Reactions: Anxiety, Hypersensitivity, Nasopharyngitis, Pain in Extremity, Drug Ineffective, Pain, Disturbance in Attention, Somnolence, Accidental Overdose

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Flovent
    Dosage: unk
    Indication: Asthma

Glucotrol XL
    Dosage: unk
    Indication: Diabetes Mellitus
    Start date: 2006-12-01

Benadryl
    Dosage: unk
    Indication: Hypersensitivity
    Start date: 2012-01-15

Lyrica
    Dosage: unk
    Indication: Neuropathy Peripheral
    Start date: 2011-10-01
    End date: 2012-01-14

Other drugs received by patient: Pravastatin; Amitriptyline; Citalopram; Metoprolol; Fish OIL; Omeprazole; Actos; Metformin; Furosemide; Rapamune; Prednisone; Myfortic; Multi-Vitamins; Potassium Chloride



Possible Benadryl side effects in 53 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-15

Patient: 53 year old female

Reactions: Confusional State, Agitation, Hypersensitivity, Aphasia, Panic Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Morphine
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-11-19
    End date: 2011-11-19

Myoview
    Dosage: 814 mbq, single dose
    Indication: Abdominal Pain Upper
    Start date: 2011-11-19
    End date: 2011-11-19

Benadryl
    Indication: Pruritus
    Start date: 2011-11-19
    End date: 2011-11-19

Other drugs received by patient: Technetium (Tc99m) Generator (Manf. Unknown) (Sodium Pertechnetate TC9



Possible Benadryl side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-01

Patient: female

Reactions: Confusional State, Speech Disorder, Hypersensitivity, Pruritus

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Benadryl
    Indication: Pruritus
    Start date: 2011-11-19
    End date: 2011-11-19

Myoview
    Dosage: 925 mbq, single dose
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-11-19
    End date: 2011-11-19

Other drugs received by patient: Technetium (Tc99m) (Sodiuim Pertechnetate Tc99m)



Possible Benadryl side effects in 31 year old male

Reported by a consumer/non-health professional from United States on 2011-11-17

Patient: 31 year old male

Reactions: Asthma, Off Label Use, Hypersensitivity, Drug Ineffective FOR Unapproved Indication

Drug(s) suspected as cause:
Benadryl
    Administration route: Oral

Benadryl
    Dosage: once
    Administration route: Oral
    Indication: Hypersensitivity
    Start date: 2011-11-06

Other drugs received by patient: Lantus



Possible Benadryl side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-11

Patient: female, weighing 93.4 kg (205.5 pounds)

Reactions: Hypersensitivity, Rash

Drug(s) suspected as cause:
Effexor
    Dosage: 50 mg, 2x/day
    Administration route: Oral
    Indication: Depression
    Start date: 2010-05-01
    End date: 2010-01-01

Benadryl
    Dosage: unk
    Indication: Dermatitis Allergic
    Start date: 2010-01-01

Effexor
    Dosage: unk
    Start date: 2010-08-01

Other drugs received by patient: Codeine Phosphate / Paracetamol; Ambien; Folic Acid; Humira; Methotrexate; Prevacid; Xanax; Triamterene and Hydrochlorothiazide; Nexiclon XR

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