This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Chlorpromazine and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (54)
Death (16)
Life Threatening Events (1)
Disability (2)
Reports by Reaction Type
Completed Suicide (10),
Cleft Palate (9),
Maternal Drugs Affecting Foetus (6),
Toxicity To Various Agents (6),
Head Injury (5),
Contusion (4),
Drug Abuse (4),
Laceration (4),
Atrial Fibrillation (4),
Pyrexia (3),
Sydenham's Chorea (3),
Dystonia (3)
Below are a few examples of reports where side effects / adverse reactions may be related to Chlorpromazine. For a complete list or a specific selection of reports, please use the links above.
Possible Chlorpromazine side effects in male
Reported by a physician from United Kingdom on 2012-08-27
Patient: male, weighing 2.2 kg (4.8 pounds)
Reactions: Neonatal Respiratory Distress Syndrome, Premature Baby, Hypocalcaemia, Pneumothorax, Drug Withdrawal Syndrome Neonatal
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 25mg per day
Indication: Anxiety
Start date: 2011-09-22
Citalopram Hydrobromide
Dosage: 20mg per day
Indication: Depression
Start date: 2011-10-04
Dihydrocodeine
Dosage: 60mg per day
Indication: Pain
Start date: 2010-03-15
Fluoxetine
Dosage: 60mg per day
Indication: Depression
Start date: 2010-06-21
End date: 2011-10-04
Omeprazole
Dosage: 20mg per day
Indication: Dyspepsia
Start date: 2008-09-19
Propranolol
Dosage: 20mg per day
Indication: Anxiety
Start date: 2009-05-05
Propranolol
Dosage: 20mg per day
Indication: Palpitations
Start date: 2009-05-05
Seroquel
Dosage: 400mg per day
Indication: Anxiety
Start date: 2011-03-23
End date: 2011-09-10
Seroquel
Dosage: 400mg per day
Indication: Depression
Start date: 2011-03-23
End date: 2011-09-10
Possible Chlorpromazine side effects in female
Reported by a physician from Japan on 2012-08-06
Patient: female, weighing 59.0 kg (129.8 pounds)
Reactions: Toxicity To Various Agents
Adverse event resulted in: death
Drug(s) suspected as cause:
Amoxapine
Dosage: unk
Chlorpromazine
Dosage: unk
Mirtazapine
Dosage: unk
Zoloft
Dosage: unk
Zolpidem
Dosage: unk
Possible Chlorpromazine side effects in 34 year old female
Reported by a physician from Taiwan, Province of China on 2012-07-13
Patient: 34 year old female
Reactions: Respiratory Rate Increased, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Chloride Decreased, Tongue DRY, Blood Potassium Increased, Blood PH Decreased, Body Temperature Decreased, Mucosal Dryness, Muscle Rigidity, Heart Rate Increased, Depressed Level of Consciousness, Blood Sodium Decreased, Blood Creatinine Increased, Diabetic Hyperosmolar Coma
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 100 mg, qd
Indication: Binge Drinking
Haloperidol
Dosage: 20 mg, qd
Indication: Binge Drinking
Lithium Carbonate
Indication: Bipolar Disorder
Trihexyphenidyl HCL
Dosage: 4 mg, qd
Indication: Binge Drinking
Possible Chlorpromazine side effects in 31 year old male
Reported by a pharmacist from United States on 2012-07-05
Patient: 31 year old male, weighing 92.1 kg (202.6 pounds)
Reactions: Priapism
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 100 mg hs po
Administration route: Oral
Indication: Psychotic Disorder
Start date: 2012-02-10
End date: 2012-03-07
Citalopram 10 MG Torrent Pharma
Dosage: 30 mg am po
Administration route: Oral
Indication: Depression
Start date: 2012-02-09
End date: 2012-03-04
Possible Chlorpromazine side effects in 80 year old female
Reported by a physician from United States on 2012-06-25
Patient: 80 year old female
Reactions: Eyelid Oedema, Corneal Neovascularisation, Conjunctival Oedema, Lagophthalmos, Conjunctival Hyperaemia, Keratopathy, Corneal Oedema, Erythema, Eye Pain
Drug(s) suspected as cause:
Chlorpromazine
Possible Chlorpromazine side effects in female
Reported by a physician from India on 2012-06-20
Patient: female
Reactions: Weight Increased, Blood Prolactin Increased, Amenorrhoea, Polycystic Ovaries, Decreased Appetite
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 200 mg, 1 d, unknown
Indication: Product Used FOR Unknown Indication
Risperidone
Dosage: 6 mg, 1 d, unknown
Indication: Product Used FOR Unknown Indication
Topiramate
Dosage: 25 mg, 1 d, unknown
Indication: Product Used FOR Unknown Indication
Trihexyphenidyl HCL
Dosage: 4 mg, 1 d, unknown
Indication: Product Used FOR Unknown Indication
Possible Chlorpromazine side effects in 64 year old
Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-11
Patient: 64 year old
Reactions: Completed Suicide
Adverse event resulted in: death
Drug(s) suspected as cause:
Calan
Dosage: unk
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Chlorpromazine
Dosage: unk
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Possible Chlorpromazine side effects in 64 year old
Reported by a pharmacist from United States on 2012-06-11
Patient: 64 year old
Reactions: Completed Suicide, Toxicity To Various Agents
Adverse event resulted in: death
Drug(s) suspected as cause:
Calan
Administration route: Oral
Indication: Hypertension
Chlorpromazine
Administration route: Oral
Indication: Ill-Defined Disorder
Possible Chlorpromazine side effects in 27 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-05-30
Patient: 27 year old female, weighing 70.0 kg (154.0 pounds)
Reactions: Myoglobinuria, Pneumonia, Incorrect Dose Administered, Neuroleptic Malignant Syndrome, Joint Ankylosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Possible Chlorpromazine side effects in 38 year old female
Reported by a consumer/non-health professional from Brazil on 2012-05-16
Patient: 38 year old female
Reactions: Overdose, Suicide Attempt, Somnolence
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 4tab single dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-05-09
End date: 2012-05-09
Clonazepam
Dosage: 15tab single dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-05-09
End date: 2012-05-09
Zofran
Dosage: 1tab single dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-05-09
End date: 2012-05-09
Possible Chlorpromazine side effects in male
Reported by a consumer/non-health professional from United States on 2012-04-23
Patient: male
Reactions: Cataract, Drug Ineffective, Adverse Drug Reaction, Squamous Cell Carcinoma of Skin
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Indication: Hallucination
Chlorpromazine
Indication: Schizophrenia
Invega
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2005-01-01
End date: 2011-01-01
Risperdal
Dosage: began 15 years ago on an unspecified date in 1997
Risperdal
Start date: 2011-01-01
Risperdal
Dosage: began 15 years ago on an unspecified date in 1997
Indication: Hallucination
Risperdal
Start date: 2011-01-01
Risperdal
Indication: Schizophrenia
Start date: 2011-01-01
Risperdal
Dosage: began 15 years ago on an unspecified date in 1997
Indication: Autism
Risperdal Consta
Indication: Product Used FOR Unknown Indication
Risperdal Consta
Other drugs received by patient: Levothyroxine Sodium; Depakote; Diphenhydramine HCL; Fluvoxamine Maleate; Paxil; Benztropine Mesylate; Benztropine Mesylate; Lorazepam
Possible Chlorpromazine side effects in 52 year old female
Reported by a physician from Turkey on 2012-04-20
Patient: 52 year old female
Reactions: Pneumonia Aspiration, Supraventricular Tachycardia, Coma, Toxicity To Various Agents, Electroencephalogram Abnormal, Neurotoxicity, Renal Failure, Respiratory Failure, Dehydration, Acute Respiratory Distress Syndrome, Hyperthyroidism
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 200 mg
Indication: Bipolar Disorder
Dexamethasone
Indication: Supraventricular Tachycardia
Dexamethasone
Dosage: 2 mg
Indication: Hyperthyroidism
Diuretics
Indication: Hypertension
Insuline Glargine
Indication: Diabetes Mellitus
Irbesartane
Indication: Hypertension
Lithium Carbonate
Indication: Bipolar Disorder
Phenytoin
Dosage: 300 mg
Indication: Convulsion
Propranolol
Indication: Supraventricular Tachycardia
Propranolol
Dosage: 160 mg
Indication: Hyperthyroidism
Propyl-Thiouracil
Indication: Supraventricular Tachycardia
Propyl-Thiouracil
Dosage: 600 mg
Indication: Hyperthyroidism
Possible Chlorpromazine side effects in 55 year old male
Reported by a physician from Turkey on 2012-04-02
Patient: 55 year old male
Reactions: Hepatitis C, Increased Appetite, Cerebral Atrophy, Treatment Noncompliance
Drug(s) suspected as cause:
Biperiden Hydrochloride TAB
Indication: Hypomania
Chlorpromazine
Indication: Hypomania
Clonazepam
Indication: Hypomania
Haloperidol
Indication: Hypomania
Risperdal Consta
Indication: Hypomania
Risperidone
Administration route: Oral
Risperidone
Administration route: Oral
Indication: Hypomania
Other drugs received by patient: Enalapril; Pioglitazone; Metformin HCL
Possible Chlorpromazine side effects in 25 year old female
Reported by a pharmacist from Japan on 2012-03-30
Patient: 25 year old female
Reactions: Intentional Overdose, Toxicity To Various Agents
Adverse event resulted in: death
Drug(s) suspected as cause:
Amobarbital
Dosage: unk
Chlorpromazine
Dosage: unk
Levomepromazine
Dosage: unk
Paroxetine HCL
Dosage: unk
Phenobarbital TAB
Dosage: unk
Promethazine
Dosage: unk
Triazolam
Dosage: unk
Possible Chlorpromazine side effects in 35 year old male
Reported by a physician from Iran (Islamic Republic OF) on 2012-02-17
Patient: 35 year old male
Reactions: Treatment Failure, Priapism
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 50 mg;hs
Indication: Insomnia
Risperidone
Dosage: 3 mg;qd
Indication: Borderline Personality Disorder
Risperidone
Dosage: 3 mg;qd
Indication: Schizophrenia
Other drugs received by patient: Biperiden Hydrochloride TAB; Clonazepam
Possible Chlorpromazine side effects in 57 year old female
Reported by a physician from United States on 2012-01-24
Patient: 57 year old female
Reactions: Completed Suicide
Adverse event resulted in: death
Drug(s) suspected as cause:
Carbamazepine
Dosage: unk, unknown
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Chlorpromazine
Dosage: unk, unknown
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Possible Chlorpromazine side effects in 38 year old female
Reported by a pharmacist from United States on 2012-01-24
Patient: 38 year old female, weighing 72.0 kg (158.4 pounds)
Reactions: Blood Alkaline Phosphatase Increased, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased
Drug(s) suspected as cause:
Chlorpromazine
Possible Chlorpromazine side effects in male
Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-01-23
Patient: male, weighing 3.8 kg (8.4 pounds)
Reactions: Regurgitation, Maternal Drugs Affecting Foetus, Dystonia, Retching, Flatulence, Agitation Neonatal, Hypertonia Neonatal
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amitriptyline HCL
Dosage: 1 dosage form (1 dosage forms, 1 in 1 d), transplacental
Chlorpromazine
Dosage: 75 mg daily before third quarter of pregnancy (75 mg, 1 in 1 d), transplacental, daily dose decrease
Escitalopram Oxalate
Dosage: transplacental
End date: 2011-11-26
Oxazepam
Dosage: 20 mg (20 mg, 1 in 1 d), transplacental
Prazepam
Dosage: switched to oxazepam at the third quarter, transplacental
Possible Chlorpromazine side effects in 82 year old female
Reported by a physician from United States on 2012-01-17
Patient: 82 year old female
Reactions: Completed Suicide, Respiratory Arrest, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Chlorpromazine
Clopidogrel
Diltiazem Hydrochloride
Metformin / Sitagliptin (Metformin, Sitagliptin)
Possible Chlorpromazine side effects in male
Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-01-17
Patient: male, weighing 3.8 kg (8.4 pounds)
Reactions: Regurgitation, Maternal Drugs Affecting Foetus, Dystonia, Retching, Flatulence, Agitation Neonatal, Hypertonia Neonatal
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amitriptyline HCL
Dosage: 1 dosage form (1 dosage forms, 1 in 1 d), transplacental
Chlorpromazine
Dosage: 75 mg daily before third quarter of pregnancy (75 mg, 1 in 1 d), transplacental
Escitalopram Oxalate
Dosage: transplacental
End date: 2011-11-26
Oxazepam
Dosage: 20 mg daily up to third quarter (20 mg, 1 in 1 d), transplacental
Prazepam
Dosage: switched to oxazepam at the third quarter, transplacental
Possible Chlorpromazine side effects in 5 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-10
Patient: 5 year old male
Reactions: Speech Disorder, Trismus, Dyskinesia, Coordination Abnormal, Tongue Paralysis, Sydenham's Chorea, Aggression
Drug(s) suspected as cause:
Chlorpromazine
Dosage: 200 mg, qd
Indication: Abnormal Behaviour
Dextroamphetamine
Dosage: 2.5 mg, tid
Possible Chlorpromazine side effects in 67 year old male
Reported by a pharmacist from United States on 2012-01-04
Patient: 67 year old male, weighing 83.5 kg (183.6 pounds)
Reactions: Corneal Opacity
Drug(s) suspected as cause:
Chlorpromazine
Possible Chlorpromazine side effects in 82 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-04
Patient: 82 year old female
Reactions: Incorrect Dose Administered, Completed Suicide, Toxicity To Various Agents
Adverse event resulted in: death
Drug(s) suspected as cause:
Chlorpromazine
Dosage: (df)
Indication: Product Used FOR Unknown Indication
Clopidogrel
Dosage: (df)
Indication: Product Used FOR Unknown Indication
Diltiazem
Dosage: (df oral)
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Metformin HCL
Dosage: (df)
Indication: Product Used FOR Unknown Indication
Possible Chlorpromazine side effects in 56 year old female
Reported by a physician from United States on 2012-01-04
Patient: 56 year old female
Reactions: Death, Cardio-Respiratory Arrest, Completed Suicide
Adverse event resulted in: death
Drug(s) suspected as cause:
Chlorpromazine
Dosage: unk, unknown
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Clonazepam
Dosage: unk, unknown
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Propoxyphene Hydrochloride
Dosage: unk, unknown
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Possible Chlorpromazine side effects in 23 year old male
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-12-29
Patient: 23 year old male
Reactions: Pyrexia, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Indication: Product Used FOR Unknown Indication
Valproate Sodium
Dosage: 500mg daily, 250mg, twice a day
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Procyclidine Hydrochloride 2MG TAB; Lactulose
Possible Chlorpromazine side effects in 82 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-28
Patient: 82 year old female
Reactions: Completed Suicide, Toxicity To Various Agents, Intentional Drug Misuse
Adverse event resulted in: death
Drug(s) suspected as cause:
Chlorpromazine
Administration route: Oral
Clopidogrel Bisulfate
Administration route: Oral
Diltiazem
Administration route: Oral
Sitagliptin and Metformin Hydrochloride
Administration route: Oral
Possible Chlorpromazine side effects in male
Reported by a physician from Italy on 2011-12-22
Patient: male
Reactions: Contusion, Head Injury, Atrial Fibrillation, Laceration, Drug Abuse
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Chlorpromazine
Dosage: unk
Administration route: Oral
Indication: Abnormal Behaviour
Start date: 2010-09-18
End date: 2010-09-18
Paroxetine Hydrochloride
Dosage: 20 mg, single
Administration route: Oral
Indication: Abnormal Behaviour
Start date: 2010-09-18
End date: 2010-09-18
Ramipril
Dosage: unk
Administration route: Oral
Start date: 2010-09-18
End date: 2010-09-18
Possible Chlorpromazine side effects in 41 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-20
Patient: 41 year old male
Reactions: Antipsychotic Drug Level Increased, Drug Level Increased, Completed Suicide
Adverse event resulted in: death
Drug(s) suspected as cause:
Bupropion HCL
Chlorpromazine
Administration route: Oral
Clozapine
Administration route: Oral
Zolpidem
Possible Chlorpromazine side effects in 41 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-20
Patient: 41 year old male
Reactions: Antipsychotic Drug Level Increased, Drug Level Increased, Completed Suicide
Adverse event resulted in: death
Drug(s) suspected as cause:
Bupropion HCL
Chlorpromazine
Administration route: Oral
Clozapine
Administration route: Oral
Zolpidem
Possible Chlorpromazine side effects in 15 year old male
Reported by a health professional (non-physician/pharmacist) from Italy on 2011-12-14
Patient: 15 year old male
Reactions: Head Injury, Multiple Drug Overdose Intentional, Self Injurious Behaviour, Injury
Drug(s) suspected as cause:
Chlorpromazine
Dosage: half bottle
Administration route: Oral
Indication: Ill-Defined Disorder
Start date: 2011-12-06
Haldol
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-06
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