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Clozapine (Clozapine) - Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neutropenia (133)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozapine where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 133   Next >>

Possible Clozapine side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-08-04

Patient: 49 year old female

Reactions: Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine
    Dosage: 650 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-01-01
    End date: 2012-01-09

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depression
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Zopiclone; Amoxicillin



Possible Clozapine side effects in male

Reported by a physician from United Kingdom on 2012-08-02

Patient: male

Reactions: Stereotypy, Abnormal Behaviour, Schizophrenia, Sexually Inappropriate Behaviour, Delusion, Aggression, Dysarthria, Apathy, Thinking Abnormal, Psychotic Disorder, Insomnia, Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Zuclopenthixol Decanoate; Olanzapine; Chlorpromazine HCL; Carbamazepine; Diazepam; Lactulose; Quetiapine; Clonazepam; Valproate Sodium



Possible Clozapine side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-02

Patient: 60 year old female

Reactions: Urinary Tract Infection, Depression, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 25 mg, daily
    Indication: Psychotic Disorder
    Start date: 2011-12-28
    End date: 2012-05-30

Clozapine
    Dosage: 12.5 mg, daily
    Start date: 2012-06-13
    End date: 2012-06-18

Clozapine
    Dosage: 50 mg, daily
    Start date: 2012-01-01

Mianserine G GAM
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Depression
    Start date: 2012-05-25
    End date: 2012-05-31

Other drugs received by patient: Lithium Carbonate; Calcium Carbonate; Modopar; Azilect; Sinemet; Oxybutynin; Stalevo 100; Mirtazapine; Rivotril; Atarax; Acid Alendronique



Possible Clozapine side effects in 60 year old female

Reported by a pharmacist from France on 2012-07-30

Patient: 60 year old female

Reactions: Urinary Tract Infection, Depression, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 50 mg, daily
    Start date: 2012-01-01

Clozapine
    Dosage: 12.5 mg, daily
    Start date: 2012-06-13
    End date: 2012-06-18

Clozapine
    Dosage: 25 mg, daily
    Indication: Psychotic Disorder
    Start date: 2011-12-28
    End date: 2012-05-30

Mianserine G GAM
    Dosage: 10 mg, unk
    Administration route: Oral
    Indication: Depression
    Start date: 2012-05-25
    End date: 2012-05-31

Other drugs received by patient: Atarax; Acid Alendronique; Lithium Carbonate; Sinemet; Oxybutynin; Modopar; Calcium Carbonate; Mirtazapine; Azilect; Stalevo 100; Clonazepam



Possible Clozapine side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from Mexico on 2012-07-27

Patient: 26 year old female

Reactions: Catatonia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amantadine HCL
    Dosage: 300 mg
    Indication: Catatonia

Clozapine
    Dosage: 100 mg
    Indication: Catatonia

Lorazepam
    Dosage: 12 mg
    Administration route: Oral
    Indication: Catatonia

Olanzapine
    Dosage: 20 mg
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2 mg
    Indication: Catatonia

Zuclopenthixol Depot
    Indication: Aggression



Possible Clozapine side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-07-26

Patient: 49 year old female

Reactions: Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine
    Dosage: 650 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-01-01
    End date: 2012-01-09

Mirtazapine
    Dosage: 45 mg, qd
    Administration route: Oral
    Indication: Depression
    End date: 2012-01-21

Topiramate
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Amoxicillin; Zopiclone



Possible Clozapine side effects in 77 year old male

Reported by a consumer/non-health professional from Australia on 2012-07-25

Patient: 77 year old male

Reactions: Epididymitis, Chills, Sepsis, Neutropenia

Drug(s) suspected as cause:
Abilify

Clozapine



Possible Clozapine side effects in 31 year old female

Reported by a physician from Korea, Republic of on 2012-07-25

Patient: 31 year old female

Reactions: Grand MAL Convulsion, Neutropenia

Drug(s) suspected as cause:
Clozapine
    Dosage: daily
    Indication: Schizophrenia
    Start date: 2008-11-13
    End date: 2008-11-21

Olanzapine
    Start date: 2008-01-01
    End date: 2008-01-01

Olanzapine
    Dosage: daily
    Indication: Schizophrenia

Valproate Sodium
    Dosage: daily
    End date: 2008-12-02

Valproate Sodium
    Dosage: daily
    Indication: Schizophrenia
    Start date: 2008-01-01

Other drugs received by patient: Haloperidol



Possible Clozapine side effects in 35 year old male

Reported by a consumer/non-health professional from Finland on 2012-07-25

Patient: 35 year old male

Reactions: Neutropenia, Idiopathic Thrombocytopenic Purpura, Thrombocytopenia, Leukopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 600 mg, per day
    Start date: 2007-01-01

Clozapine
    Dosage: 600 mg, per day
    Indication: Schizophrenia

Other drugs received by patient: Bisoprolol Fumarate; Lorazepam



Possible Clozapine side effects in

Reported by a pharmacist from Spain on 2012-07-23

Patient:

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Cytomegalovirus Infection, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Clonazepam; Quetiapine; Lithium Carbonate; Lactulose; Lormetazepam



Possible Clozapine side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from Mexico on 2012-07-23

Patient: 26 year old female

Reactions: Condition Aggravated, Neutropenia

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg/day
    Indication: Dystonia

Olanzapine
    Dosage: titrated up to 20 mg/day
    Indication: Psychomotor Hyperactivity

Risperidone
    Indication: Catatonia

Risperidone
    Dosage: 2 mg, unk
    Indication: Psychotic Disorder

Zuclopenthixol
    Dosage: unk
    Indication: Aggression



Possible Clozapine side effects in 39 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-17

Patient: 39 year old female

Reactions: Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acetaminophen and Tramadol HCL
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-01-14
    End date: 2010-02-22

Clopixol
    Administration route: Oral
    Start date: 2010-01-14
    End date: 2010-02-22

Clopixol
    Indication: Schizophrenia
    Start date: 2010-02-09
    End date: 2010-02-22

Clopixol
    Start date: 2010-02-09
    End date: 2010-02-22

Clopixol
    Administration route: Oral
    Start date: 2010-01-14
    End date: 2010-02-22

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-01-25
    End date: 2010-02-18

Equanil
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-01-14
    End date: 2010-02-24

Heptaminol Hydrochloride
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2010-02-23

Loxapine HCL
    Indication: Schizophrenia
    End date: 2010-02-22

Other drugs received by patient: Mepronizine; Polyethylene Glycol; Lansoprazole; Parkinane LP



Possible Clozapine side effects in 49 year old female

Reported by a physician from United Kingdom on 2012-07-13

Patient: 49 year old female

Reactions: Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-01-01
    End date: 2012-01-09

Mirtazapine
    Administration route: Oral
    Indication: Depression
    End date: 2012-01-21

Topiramate
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2007-01-01
    End date: 2012-01-21

Other drugs received by patient: Zopiclone; Amoxicillin



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-13

Patient: female

Reactions: White Blood Cell Count Decreased, B-Cell Lymphoma, Paranoia, Lymphopenia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21



Possible Clozapine side effects in 26 year old female

Reported by a physician from Mexico on 2012-07-13

Patient: 26 year old female

Reactions: Disease Recurrence, Catatonia, Condition Aggravated, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Indication: Catatonia

Clozapine
    Dosage: 100 milligram; later restarted
    Indication: Dystonia

Olanzapine
    Dosage: titrated up to 20 mg/d
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2mg
    Indication: Psychotic Disorder

Zuclopenthixol
    Indication: Aggression

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from Mexico on 2012-07-11

Patient: 26 year old female

Reactions: Condition Aggravated, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Olanzapine
    Dosage: titrated to 20 mg/day
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2 mg, unk
    Indication: Product Used FOR Unknown Indication

Zuclopenthixol
    Dosage: unk
    Indication: Aggression



Possible Clozapine side effects in 26 year old female

Reported by a individual with unspecified qualification from Mexico on 2012-07-11

Patient: 26 year old female

Reactions: Disease Recurrence, NO Therapeutic Response, Catatonia, Cerebral Atrophy, Condition Aggravated, Neutropenia, Aggression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg;unk;qd
    Indication: Dystonia

Clozapine
    Dosage: 100 mg;unk;qd
    Indication: Catatonia

Olanzapine
    Dosage: 200 mg; qd
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2 mg;
    Indication: Psychotic Disorder

Zuclopenthixol (Zuclopenthixol)
    Indication: Aggression

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-11

Patient: female

Reactions: White Blood Cell Count Decreased, Paranoia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25



Possible Clozapine side effects in 26 year old female

Reported by a physician from Mexico on 2012-07-06

Patient: 26 year old female

Reactions: Catatonia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Catatonia

Clozapine

Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Dystonia

Clozapine

Olanzapine
    Dosage: titrated up to 20 mg/d
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2mg
    Indication: Psychotic Disorder

Zuclopenthixol
    Dosage: depot
    Indication: Aggression

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in 26 year old female

Reported by a physician from Mexico on 2012-07-06

Patient: 26 year old female

Reactions: Catatonia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Catatonia

Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Dystonia

Clozapine

Clozapine

Olanzapine
    Dosage: titrated up to 20 mg/d
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2mg
    Indication: Psychotic Disorder

Zuclopenthixol
    Dosage: depot
    Indication: Aggression

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in 26 year old female

Reported by a physician from Mexico on 2012-07-06

Patient: 26 year old female

Reactions: Catatonia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Catatonia

Clozapine
    Dosage: 100 mg/d; later restarted
    Indication: Dystonia

Clozapine

Clozapine

Olanzapine
    Dosage: titrated up to 20 mg/d
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2mg
    Indication: Psychotic Disorder

Zuclopenthixol
    Dosage: depot
    Indication: Aggression

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from Mexico on 2012-07-05

Patient: 26 year old female

Reactions: Condition Aggravated, Catatonia, Neutropenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg, daily

Olanzapine
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2 mg, unk

Zuclopenthixol
    Indication: Aggression



Possible Clozapine side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from Mexico on 2012-07-05

Patient: 26 year old female

Reactions: Condition Aggravated, Catatonia, Neutropenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 100 mg, daily

Olanzapine
    Indication: Psychomotor Hyperactivity

Risperidone
    Dosage: 2 mg, unk

Zuclopenthixol
    Indication: Aggression



Possible Clozapine side effects in male

Reported by a physician from United Kingdom on 2012-06-29

Patient: male

Reactions: Mental Impairment, Overdose, Full Blood Count Abnormal, Suicide Attempt, Neutropenia, Aggression

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Hydrocortisone Acetate; Levothyroxine; Quetiapine; Risperidone; Zopiclone; Valproate Sodium; Clopixol; Lorazepam



Possible Clozapine side effects in 21 year old male

Reported by a physician from United States on 2012-06-28

Patient: 21 year old male

Reactions: White Blood Cell Count Decreased, Agranulocytosis, Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Clozapine



Possible Clozapine side effects in 43 year old male

Reported by a physician on 2012-06-28

Patient: 43 year old male

Reactions: Back Pain, White Blood Cell Count Decreased, Drug Interaction, Neutropenia

Drug(s) suspected as cause:
Acetaminophen W / Codeine
    Indication: Back Pain

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-07-01
    End date: 2012-04-25

Ibuprofen
    Indication: Back Pain

Lamotrigine
    Dosage: 200 mg (200 mg,1 in 1 d)
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Sulprid (Sulpiride)



Possible Clozapine side effects in 21 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 21 year old male

Reactions: Pyrexia, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Risperidone



Possible Clozapine side effects in female

Reported by a physician from Australia on 2012-06-28

Patient: female

Reactions: White Blood Cell Count Decreased, Paranoia, Burkitt's Lymphoma, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Clozapine
    Dosage: 400 mg, qd

Clozaril
    Dosage: 200 mg, unk
    Start date: 2011-07-04
    End date: 2011-07-18

Clozaril
    Dosage: 400 mg, unk
    Start date: 2011-08-01
    End date: 2011-09-05

Clozaril
    Dosage: 500 mg, unk
    Start date: 2011-09-20
    End date: 2011-11-23

Clozaril
    Dosage: 700 mg, unk
    Start date: 2010-07-27
    End date: 2010-09-21

Clozaril
    Dosage: 750 mg, unk
    Start date: 2007-02-06
    End date: 2007-07-27

Clozaril
    Dosage: 650 mg, unk
    Start date: 2010-10-18
    End date: 2011-05-30

Clozaril
    Start date: 2004-02-04

Clozaril
    Dosage: 475 mg, unk
    Start date: 2011-12-15
    End date: 2012-02-17

Clozaril
    Dosage: 450 mg, unk
    Start date: 2012-02-20

Clozaril
    Dosage: 800 mg, unk
    Start date: 2007-08-21
    End date: 2009-11-02

Clozaril
    Dosage: 750 mg, unk
    Start date: 2009-11-30
    End date: 2010-06-28

Clozaril
    Dosage: 450 mg, daily
    Start date: 2005-02-23

Clozaril
    Dosage: 300 mg, unk
    Start date: 2011-07-19
    End date: 2011-07-25



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-06-22

Patient: female, weighing 100.0 kg (220.0 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Increased, Neoplasm Malignant, Ear Infection, Neutropenia, Neutrophil Count Decreased, Lymphoma, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 200 mg, unk
    Start date: 1997-10-03

Clozaril
    Dosage: 200 mg, unk
    Administration route: Oral
    Start date: 1997-10-03

Clozaril
    Dosage: 250 mg, unk
    Start date: 2012-05-08

Clozaril
    Dosage: 200 mg, unk

Other drugs received by patient: Chlorhexidine Gluconate; Fludrocortisone Acetate; Ranitidine; Potassium Chloride; Valproate Sodium; Senna-Mint WAF; Magnesium Aspartate; Pravastatin; Nystatin; Gliclazide; Sulfamethoxazole and Trimethoprim; Valaciclovir; Docusate



Possible Clozapine side effects in 43 year old male

Reported by a physician from United Kingdom on 2012-06-22

Patient: 43 year old male

Reactions: White Blood Cell Count Decreased, Back Pain, Drug Interaction, Neutropenia, Neutrophil Count Decreased

Drug(s) suspected as cause:
Acetaminophen and Codeine Phosphate
    Indication: Back Pain

Clozapine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Administration route: Oral
    Start date: 2005-07-01
    End date: 2012-04-25

Other drugs received by patient possibly interacting with the suspect drug:
Ibuprofen
    Indication: Back Pain

Lamotrigine
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Sulpiride



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