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Clozapine (Clozapine) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (122)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Clozapine where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 122   Next >>

Possible Clozapine side effects in 36 year old female

Reported by a physician from United Kingdom on 2012-08-27

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Neutrophil Count Increased, Hiatus Hernia, Cardiac Murmur, Urinary Tract Infection, Physical Assault, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Furosemide; Ramipril; Atorvastatin; Bendroflumethiazide; Aripiprazole



Possible Clozapine side effects in female

Reported by a physician from United Kingdom on 2012-08-21

Patient: female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, Aggression, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk ukn, qd

Clozapine
    Dosage: unk ukn, unk
    Start date: 2008-05-19

Clozaril
    Administration route: Oral
    Start date: 2008-06-05

Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2008-05-19

Diazepam
    Dosage: unk ukn, prn

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Administration route: Oral

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral

Lactulose
    Dosage: 10 ml, prn

Lansoprazole
    Dosage: 30 mg, qd
    Administration route: Oral

Perindopril Erbumine
    Dosage: 2 mg, qd
    Administration route: Oral

Trimethoprim
    Dosage: unk ukn, unk
    Indication: Urinary Tract Infection

Zopiclone
    Dosage: 3.75 mg, qhs

Other drugs received by patient: Furosemide; Atorvastatin; Abilify; Ramipril; Bendrofluazide



Possible Clozapine side effects in 39 year old female

Reported by a physician from Spain on 2012-08-20

Patient: 39 year old female

Reactions: Pleuropericarditis, Pleural Effusion, Toxicity To Various Agents, Pyrexia, Leukocytosis, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Lithium



Possible Clozapine side effects in female

Reported by a physician from Norway on 2012-08-20

Patient: female

Reactions: C-Reactive Protein Increased, Chills, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Pyrexia, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Vallergan; AFI-D2-Forte; Seroquel



Possible Clozapine side effects in 36 year old female

Reported by a physician from United Kingdom on 2012-08-16

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Physical Assault, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozapine
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Atorvastatin; Bendroflumethiazide; Furosemide; Aripiprazole; Ramipril



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-09

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Neutrophil Count Increased, Cardiac Murmur, Hiatus Hernia, Urinary Tract Infection, Physical Assault, Skin Disorder, Monocyte Count Increased, Aggression, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2008-06-05

Clozapine
    Dosage: unk
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Diazepam
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Dosage: 10 ml, prn
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Dosage: 30 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Dosage: 2 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Dosage: unk
    Indication: Urinary Tract Infection

Zopiclone (Unknown)
    Dosage: 3.75 mg, daily, nocte
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Furosemide; Ramipril; Aripiprazole; Atorvastatin; Bendrofluazide; Abilify; Zopiclone



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-08-08

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Cardiac Murmur, Neutrophil Count Increased, Diabetes Mellitus, Physical Assault, Skin Disorder, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Staphylococcal Infection, Thrombocytosis, Blood Culture Positive, Sinus Tachycardia, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: po
    Administration route: Oral
    Start date: 2008-05-19

Clozaril
    Dosage: 250 mg;qd;po
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg;qd;po
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam

Enulose
    Dosage: 10 ml

Ferrous Sulfate TAB
    Dosage: 200 mg;bid;po
    Administration route: Oral

Folic Acid
    Dosage: 5 mg;qd;po
    Administration route: Oral

Lansoprazole
    Dosage: 30 mg;qd;po
    Administration route: Oral

Perindopril Erbumine
    Dosage: 2 mg;qd;po
    Administration route: Oral

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone (Zopiclone)
    Dosage: 3.75 mg

Other drugs received by patient: Atorvastatin; Bendroflumethiazide; Ramipril; Zopiclone; Abilify; Furosemide; Aripiprazole



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-06

Patient: female, weighing 50.0 kg (110.0 pounds)

Reactions: Electroencephalogram Abnormal, Hepatic Function Abnormal, Dyskinesia, Suicide Attempt, Pyrexia, Salivary Hypersecretion, Tremor, Inflammation

Drug(s) suspected as cause:
Clozapine
    Dosage: 200 mg, qd
    Administration route: Oral
    Start date: 2010-03-29

Clozapine
    Dosage: 300 mg, qd
    Administration route: Oral
    Start date: 2010-04-09

Clozapine
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-03-12

Clozapine
    Dosage: 150 mg, qd
    Administration route: Oral
    Start date: 2010-03-15

Clozapine
    Dosage: 275 mg, qd
    Administration route: Oral
    Start date: 2010-04-07

Clozapine
    Dosage: 250 mg, qd
    Administration route: Oral
    Start date: 2010-04-05

Clozapine
    Dosage: 12.5 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-03-01

Clozapine
    Dosage: 100 mg, qd
    Administration route: Oral
    Start date: 2010-03-10

Clozapine
    Dosage: 225 mg, qd
    Administration route: Oral
    Start date: 2010-04-02

Clozapine
    Dosage: 600 mg, qd
    Start date: 2010-05-14

Clozapine
    Dosage: 25 mg, qd
    Administration route: Oral
    Start date: 2010-03-02

Clozapine
    Dosage: 50 mg, qd
    Administration route: Oral
    Start date: 2010-03-05

Clozapine
    Dosage: 75 mg, qd
    Administration route: Oral
    Start date: 2010-03-08

Clozapine
    Dosage: 175 mg, qd
    Administration route: Oral
    Start date: 2010-03-23

Clozapine
    Dosage: 350 mg, qd
    Start date: 2010-04-12

Clozapine
    Dosage: 400 mg, qd
    Start date: 2010-04-14

Clozapine
    Dosage: 600 mg, qd
    Administration route: Oral
    Start date: 2010-04-26

Clozapine
    Dosage: 500 mg, qd
    Administration route: Oral
    Start date: 2010-04-19

Clozapine
    Dosage: 12.5 mg, qd
    Indication: Schizophrenia, Paranoid Type
    Start date: 2011-03-04

Clozapine
    Dosage: 450 mg, qd
    Administration route: Oral
    Start date: 2010-04-16

Clozapine
    Dosage: 525 mg, qd
    Administration route: Oral
    Start date: 2010-04-23

Other drugs received by patient: Blonanserin; Nitrazepam; Quetiapine Fumarate; Quetiapine Fumarate; Flunitrazepam; Quetiapine Fumarate; Quetiapine Fumarate; Quetiapine Fumarate; Quetiapine Fumarate; Aripiprazole; Sennoside; Quetiapine Fumarate; Seroquel; Flunitrazepam; Nitrazepam; Nitrazepam; Biperiden Hydrochloride TAB; Quetiapine Fumarate; Quetiapine Fumarate; Blonanserin; Nitrazepam; Quetiapine Fumarate; Quetiapine Fumarate



Possible Clozapine side effects in 54 year old male

Reported by a health professional (non-physician/pharmacist) from Taiwan, Province of China on 2012-08-03

Patient: 54 year old male

Reactions: Blood Alkaline Phosphatase Increased, Alanine Aminotransferase Increased, Parakeratosis, Pyrexia, Acanthosis, Skin Oedema, Rash, Pityriasis Rosea, Skin Lesion, Aspartate Aminotransferase Increased

Drug(s) suspected as cause:
Clozapine
    Dosage: 25 mg, daily
    Indication: Schizophrenia

Clozapine
    Dosage: 300 mg, daily



Possible Clozapine side effects in 36 year old female

Reported by a physician from United Kingdom on 2012-08-02

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Neutrophil Count Increased, Hiatus Hernia, Cardiac Murmur, Urinary Tract Infection, Physical Assault, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozapine
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Aripiprazole; Ramipril; Bendroflumethiazide; Atorvastatin; Furosemide



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-31

Patient: male

Reactions: Agranulocytosis, Pyrexia, Oropharyngeal Pain, Pharyngeal Erythema

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 300 mg, qd
    Start date: 2010-04-14
    End date: 2012-06-17

Effexor
    Dosage: 75 mg, qd
    Start date: 2012-01-01

Tercian
    Dosage: unk ukn, unk

Tercian
    Dosage: 25 mg, 4 times daily
    Start date: 2008-01-01
    End date: 2012-06-17

Other drugs received by patient: Lorazepam



Possible Clozapine side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-30

Patient: female

Reactions: Electroencephalogram Abnormal, Hepatic Function Abnormal, Dyskinesia, Suicide Attempt, Salivary Hypersecretion, Pyrexia, Tremor, Inflammation

Drug(s) suspected as cause:
Clozapine
    Dosage: 12.5 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2010-03-01

Clozapine
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-03-12

Clozapine
    Dosage: 200 mg, qd
    Administration route: Oral
    Start date: 2010-03-29

Clozapine
    Dosage: 225 mg, qd
    Administration route: Oral
    Start date: 2010-04-02

Clozapine
    Dosage: 400 mg, qd
    Start date: 2010-04-14

Clozapine
    Dosage: 450 mg, qd
    Administration route: Oral
    Start date: 2010-04-16

Clozapine
    Dosage: 600 mg, qd
    Start date: 2010-05-14

Clozapine
    Dosage: 150 mg, qd
    Administration route: Oral
    Start date: 2010-03-15

Clozapine
    Dosage: 250 mg, qd
    Administration route: Oral
    Start date: 2010-04-05

Clozapine
    Dosage: 275 mg, qd
    Administration route: Oral
    Start date: 2010-04-07

Clozapine
    Dosage: 12.5 mg, qd
    Start date: 2011-03-04

Clozapine
    Dosage: 25 mg, qd
    Administration route: Oral
    Start date: 2010-03-02

Clozapine
    Dosage: 75 mg, qd
    Administration route: Oral
    Start date: 2010-03-08

Clozapine
    Dosage: 100 mg, qd
    Administration route: Oral
    Start date: 2010-03-10

Clozapine
    Dosage: 500 mg, qd
    Administration route: Oral
    Start date: 2010-04-19

Clozapine
    Dosage: 525 mg, qd
    Administration route: Oral
    Start date: 2010-04-23

Clozapine
    Dosage: 50 mg, qd
    Administration route: Oral
    Start date: 2010-03-05

Clozapine
    Dosage: 175 mg, qd
    Administration route: Oral
    Start date: 2010-03-23

Clozapine
    Dosage: 600 mg, qd
    Administration route: Oral
    Start date: 2010-04-26

Clozapine
    Dosage: 300 mg, qd
    Administration route: Oral
    Start date: 2010-04-09

Clozapine
    Dosage: 350 mg, qd
    Start date: 2010-04-12

Other drugs received by patient: Sennoside; Blonanserin; Nitrazepam; Biperiden Hydrochloride TAB; Seroquel; Flunitrazepam



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-27

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, Aggression, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2008-06-05

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2008-05-19

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Dosage: 10 ml, prn
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Dosage: 30 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Dosage: 2 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Dosage: unk
    Indication: Urinary Tract Infection

Zopiclone (Unknown)
    Dosage: 3.75 mg, daily, nocte
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Atorvastatin; Ramipril; Zopiclone; Abilify; Bendrofluazide; Aripiprazole; Furosemide



Possible Clozapine side effects in 36 year old female

Reported by a physician from United Kingdom on 2012-07-26

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Physical Assault, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozapine
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Administration route: Oral
    Start date: 2008-06-05

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Furosemide; Aripiprazole; Atorvastatin; Ramipril; Bendroflumethiazide



Possible Clozapine side effects in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-07-23

Patient: 51 year old female, weighing 56.0 kg (123.2 pounds)

Reactions: Confusional State, Acquired Tracheo-Oesophageal Fistula, Haemorrhage, Pyrexia, Subclavian Vein Thrombosis, Agranulocytosis, Escherichia Test Positive, Aspiration, Oesophagitis, Respiratory Failure, Urosepsis, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Bipolar Disorder
    Start date: 2012-02-01
    End date: 2012-04-29

Seroquel
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-02-01
    End date: 2012-04-29

Other drugs received by patient: Calcimagon-D3; Lorazepam; Levothyroxine Sodium; Lithium Carbonate; Ezetimibe



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-20

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Urinary Tract Infection, Physical Assault, Skin Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Indication: Product Used FOR Unknown Indication
    Start date: 2008-06-05

Clozapine
    Start date: 2005-05-19

Clozaril
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-01-01
    End date: 2005-05-19

Clozaril
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Aripiprazole; Atorvastatin; Bendrofluazide; Furosemide; Ramipril; Abilify



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-18

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2008-06-05

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Dosage: 10 ml, prn
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Dosage: 30 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Dosage: 2 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Dosage: unk
    Indication: Urinary Tract Infection

Zopiclone (Unknown)
    Dosage: 3.75 mg, daily, nocte
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Bendrofluazide; Furosemide; Aripiprazole; Ramipril; Abilify; Zopiclone; Atorvastatin



Possible Clozapine side effects in female

Reported by a physician from United Kingdom on 2012-07-16

Patient: female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Cardiac Murmur, Hiatus Hernia, Neutrophil Count Increased, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, Aggression, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk ukn, qd

Clozapine
    Dosage: unk ukn, unk
    Start date: 2008-05-19

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2008-05-19

Clozaril
    Dosage: unk ukn, unk
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Administration route: Oral
    Start date: 2008-06-05

Clozaril
    Dosage: 250 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Dosage: unk ukn, prn

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Administration route: Oral

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral

Lactulose
    Dosage: 10 ml, prn

Lansoprazole
    Dosage: 30 mg, qd
    Administration route: Oral

Perindopril Erbumine
    Dosage: 2 mg, qd
    Administration route: Oral

Trimethoprim
    Dosage: unk ukn, unk
    Indication: Urinary Tract Infection

Zopiclone
    Dosage: 3.75 mg, qhs

Other drugs received by patient: Atorvastatin; Bendrofluazide; Frusemide; Ramipril; Abilify



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-07-16

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Haemorrhage, Diabetes Mellitus, Tachycardia, Pyrexia, Mean Cell Volume Decreased, Constipation, Treatment Noncompliance, Abdominal Tenderness, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Urinary Tract Infection, Laboratory Test Interference, Physical Assault, Skin Disorder, Neutrophilia, Thrombocytosis, Sinus Tachycardia, Staphylococcus Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: po
    Administration route: Oral
    Start date: 2008-05-19

Clozaril
    Dosage: 250 mg;qd;po
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozaril
    Dosage: 250 mg;qd;po
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Diazepam
    Dosage: 10 ml

Ferrous Sulfate TAB
    Dosage: 200 mg;bid;po
    Administration route: Oral

Folic Acid
    Dosage: 5 mg;qd;po
    Administration route: Oral

Lansoprazole
    Dosage: 30 mg;qd;po
    Administration route: Oral

Perindopril Erbumine
    Dosage: 2 mg;qd;po
    Administration route: Oral

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone (Zopiclone)
    Dosage: 3.75 mg

Other drugs received by patient: Ramipril; Bendroflumethiazide; Abilify; Atorvastatin; Zopiclone; Furosemide; Aripiprazole



Possible Clozapine side effects in 36 year old female

Reported by a physician from United Kingdom on 2012-07-13

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Cardiac Murmur, Neutrophil Count Increased, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Hypertension, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Diazepam
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Bendroflumethiazide; Ramipril; Aripiprazole; Atorvastatin; Furosemide



Possible Clozapine side effects in female

Reported by a physician from United Kingdom on 2012-07-12

Patient: female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Mean Cell Volume Decreased, Pyrexia, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Neutrophil Count Increased, Hiatus Hernia, Cardiac Murmur, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, Aggression, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk ukn, qd
    Start date: 2008-06-05

Clozapine
    Dosage: unk ukn, unk
    Start date: 2008-05-19

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Start date: 2008-05-19

Clozaril
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Administration route: Oral
    Start date: 2008-06-05

Clozaril
    Dosage: 250 mg, qd
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Diazepam
    Dosage: unk ukn, prn

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Administration route: Oral

Folic Acid
    Dosage: 5 mg, qd
    Administration route: Oral

Lactulose
    Dosage: 10 ml, prn

Lansoprazole
    Dosage: 30 mg, qd
    Administration route: Oral

Perindopril Erbumine
    Dosage: 2 mg, qd
    Administration route: Oral

Trimethoprim
    Dosage: unk ukn, unk
    Indication: Urinary Tract Infection

Zopiclone
    Dosage: 3.75 mg, qhs

Other drugs received by patient: Frusemide; Ramipril; Bendrofluazide; Atorvastatin; Abilify



Possible Clozapine side effects in female

Reported by a consumer/non-health professional from Chile on 2012-07-11

Patient: female

Reactions: Chills, Headache, Pyrexia, Eosinophil Count Increased, Discomfort, Myalgia, C-Reactive Protein Increased, Cyanosis, Arthralgia, Chest Pain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Haldol; Lamotrigine



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-06

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Neutrophil Count Increased, Cardiac Murmur, Hiatus Hernia, Physical Assault, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Dosage: 250 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Dosage: 250 mg, unknown
    Administration route: Oral
    Start date: 2008-05-19

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: unk
    Administration route: Oral
    Start date: 2008-06-05

Clozaril
    Dosage: 250 mg, daily
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2006-06-05
    End date: 2006-07-13

Clozaril
    Dosage: 250 mg daily qd
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Clozaril
    Dosage: 250 mg, unknown
    Administration route: Oral
    Start date: 2008-05-19

Diazepam
    Dosage: prn
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Dosage: 5mg qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Dosage: 10 ml, prn
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Dosage: 30 mg every day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Dosage: 2mg qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Indication: Urinary Tract Infection

Zopiclone (Unknown)
    Dosage: 3.75mg nocte
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Bendrofluazide; Ramipril; Atorvastatin; Aripiprazole; Frusemide



Possible Clozapine side effects in 47 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 47 year old male, weighing 60.8 kg (133.8 pounds)

Reactions: Pyrexia, Leukopenia

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Lisinopril; Vistaril; Lantus; Fleet Mineral OIL; Reglan; Aspirin; Novolog



Possible Clozapine side effects in 64 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 64 year old male

Reactions: Death, Abdominal Distension, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Folic Acid; Multi-Vitamin; Clonopin; Reglan; Aspirin; Furosemide



Possible Clozapine side effects in 43 year old female

Reported by a physician from United States on 2012-06-28

Patient: 43 year old female, weighing 105.2 kg (231.5 pounds)

Reactions: Vomiting, Band Neutrophil Count Increased, Diarrhoea, Nausea, Platelet Count Decreased, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Start date: 2011-01-01
    End date: 2011-11-28

Clozapine
    Indication: Schizoaffective Disorder Bipolar Type
    Start date: 2011-10-18
    End date: 2011-01-01

Other drugs received by patient: Lidoderm; Melatonin; Levothyroxine; Compazine; Ocean Nasal; Miralax / 00754501 /; Guaifenesin; Depakote; Zyprexa; Vitamin D; Folic Acid; Prilosec



Possible Clozapine side effects in 21 year old male

Reported by a pharmacist from United States on 2012-06-28

Patient: 21 year old male

Reactions: Pyrexia, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Risperidone



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-27

Patient: 36 year old female

Reactions: Body Mass Index Decreased, Diabetes Mellitus, Pyrexia, Mean Cell Volume Decreased, Constipation, Abdominal Tenderness, Malaise, Iron Deficiency Anaemia, White Blood Cell Count Increased, Hiatus Hernia, Neutrophil Count Increased, Cardiac Murmur, Urinary Tract Infection, Skin Disorder, Monocyte Count Increased, White Blood Cell Disorder, Staphylococcal Infection, Thrombocytosis, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2006-06-05
    End date: 2006-07-13

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2005-05-01
    End date: 2005-05-19

Clozapine
    Dosage: unk
    Administration route: Oral
    Start date: 2008-06-05

Clozapine
    Dosage: unk
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2008-05-19

Diazepam
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Ferrous Sulfate TAB
    Dosage: 200 mg, bid
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Lactulose
    Dosage: 10 ml, unknown
    Indication: Product Used FOR Unknown Indication

Lansoprazole
    Dosage: 30 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Perindopril Erbumine
    Dosage: 2 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Trimethoprim
    Dosage: unk
    Indication: Urinary Tract Infection

Other drugs received by patient: Zopiclone; Ramipril; Atorvastatin; Aripiprazole; Abilify; Bendrofluazide; Furosemide



Possible Clozapine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-22

Patient: male

Reactions: Confusional State, Agitation, Aphasia, Pyrexia, Disorientation, Pallor, Fall, Electroencephalogram Abnormal, Speech Disorder, Malaise, C-Reactive Protein Increased, Crepitations, Heart Rate Irregular, White Blood Cell Count Increased, Prurigo, General Physical Health Deterioration, Abnormal Behaviour, Atrial Fibrillation, Rash, Computerised Tomogram Abnormal, Diastolic Hypotension, Insomnia, Mitral Valve Incompetence, Fibrin Increased, RED Blood Cell Sedimentation Rate Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Aspirin; Tercian; Exelon; Diclofenac Sodium



Possible Clozapine side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-06-14

Patient: 36 year old female

Reactions: Abdominal Pain, Tubulointerstitial Nephritis, Metabolic Acidosis, Headache, Toxicity To Various Agents, Pyrexia, Hepatic Steatosis, Left Ventricular Dysfunction, Hepatomegaly, Malaise, C-Reactive Protein Increased, Ileus, Proteinuria, Systemic Inflammatory Response Syndrome, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clozapine

Other drugs received by patient: Valproate Sodium; Lithium Carbonate; Quetiapine Fumarate



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