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Cubicin (Daptomycin) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (14)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cubicin (Daptomycin) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Cubicin side effects in 63 year old male

Reported by a physician from United States on 2012-08-06

Patient: 63 year old male

Reactions: Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Aspartate Aminotransferase Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Crestor
    Administration route: Oral
    Indication: Acute Respiratory Distress Syndrome
    Start date: 2012-04-19
    End date: 2012-04-19

Cubicin
    Dosage: 200ml/hour, 580mg
    Start date: 2012-05-02
    End date: 2012-05-02

Crestor
    Administration route: Oral
    Indication: Sepsis
    Start date: 2012-04-19
    End date: 2012-04-19

Crestor
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-01

Crestor
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-01

Cubicin
    Dosage: 200ml/hour, 580mg
    Start date: 2012-04-30
    End date: 2012-04-30

Other drugs received by patient: Lactulose; Albumin (Human); Diuril; Flagyl; Vancomycin; Meropenem; Ferrous Sulfate and Folic Acid; Casofungin; Atrovent; Levlbuterol; Levofloxacin



Possible Cubicin side effects in 63 year old male

Reported by a physician on 2012-08-06

Patient: 63 year old male

Reactions: Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Refractory Anaemia, Haemorrhage, Hypotension, Aspartate Aminotransferase Increased, Drug Interaction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cubicin
    Start date: 2012-05-02
    End date: 2012-05-02

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-19
    End date: 2012-04-19

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-30

Cubicin
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-30
    End date: 2012-04-30

Other drugs received by patient: Levalbuterol Hydrochloride; Vancomycin; Meropenem; Chlorothiazide; Lactulose; Ferrous Sulfate TAB; Caspofungin Acetate; Flagyl; Albumin (Human); Atrovent; Levofloxacin



Possible Cubicin side effects in 63 year old male

Reported by a physician on 2012-08-01

Patient: 63 year old male

Reactions: Rhabdomyolysis, Refractory Anaemia, Blood Creatine Phosphokinase Increased, Haemorrhage, Aspartate Aminotransferase Increased, Hypotension, Drug Interaction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cubicin
    Start date: 2012-05-02
    End date: 2012-05-02

Cubicin
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-30
    End date: 2012-04-30

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-30

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-19
    End date: 2012-04-19

Other drugs received by patient: Chlorothiazide; Atrovent; Meropenem; Levofloxacin; Levalbuterol Hydrochloride; Flagyl; Albumin (Human); Caspofungin Acetate; Lactulose; Vancomycin; Ferrous Sulfate TAB



Possible Cubicin side effects in 63 year old male

Reported by a physician from United States on 2012-07-26

Patient: 63 year old male

Reactions: Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Aspartate Aminotransferase Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Crestor
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-01

Cubicin
    Dosage: 200ml/hour, 580mg
    Start date: 2012-04-30
    End date: 2012-04-30

Crestor
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-01

Crestor
    Administration route: Oral
    Indication: Sepsis
    Start date: 2012-04-19
    End date: 2012-04-19

Crestor
    Administration route: Oral
    Indication: Acute Respiratory Distress Syndrome
    Start date: 2012-04-19
    End date: 2012-04-19

Cubicin
    Dosage: 200ml/hour, 580mg
    Start date: 2012-05-02
    End date: 2012-05-02

Other drugs received by patient: Flagyl; Vancomycin; Levlbuterol; Atrovent; Meropenem; Casofungin; Diuril; Albumin (Human); Ferrous Sulfate and Folic Acid; Lactulose; Levofloxacin



Possible Cubicin side effects in 63 year old male

Reported by a physician on 2012-05-25

Patient: 63 year old male

Reactions: Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Aspartate Aminotransferase Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cubicin
    Dosage: dose unit:u
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-30
    End date: 2012-05-02

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-19
    End date: 2012-04-19

Rosuvastatin
    Administration route: Oral
    Start date: 2012-04-20
    End date: 2012-05-30

Other drugs received by patient: Ferrous Sulfate TAB; Lactulose; Flagyl; Atrovent; Vancomycin; Caspofungin Acetate; Chlorothiazide; Meropenem; Albumin (Human); Levalbuterol Hydrochloride; Levofloxacin



Possible Cubicin side effects in 48 year old male

Reported by a physician from Spain on 2012-04-18

Patient: 48 year old male, weighing 90.0 kg (198.0 pounds)

Reactions: Myositis, Drug Interaction

Drug(s) suspected as cause:
Furosemide
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-08
    End date: 2011-09-26

Vesanoid
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia
    Start date: 2011-08-26
    End date: 2011-10-07

Meropenem
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-05
    End date: 2011-09-14

Acetaminophen
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-08

Enoxaparin Sodium
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-08-26

Dexchlorpheniramine Maleate
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-16
    End date: 2011-09-22

Omeprazole
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-10-07

Acyclovir
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-11
    End date: 2011-09-13

Lactulose
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-31
    End date: 2011-09-14

Cefepime
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-03

Noxafil
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-02
    End date: 2011-09-17

Urokinase
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-15
    End date: 2011-09-15

Tazobactam
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-14
    End date: 2011-09-19

Allopurinol
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-08

Cloxacillin Sodium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-31
    End date: 2011-09-16

Levofloxacin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-18
    End date: 2011-09-28

Targocid
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-06
    End date: 2011-09-19

Cubicin
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-10
    End date: 2011-09-14

Amphotericin B
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-16
    End date: 2011-09-26

Hibor
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-07
    End date: 2011-09-30



Possible Cubicin side effects in 48 year old male

Reported by a pharmacist from Spain on 2012-04-13

Patient: 48 year old male, weighing 90.0 kg (198.0 pounds)

Reactions: Myositis, Drug Interaction

Drug(s) suspected as cause:
Acyclovir
    Dosage: 500 mg;tid;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-11
    End date: 2011-09-13

Hibor (Heparin Sodium / 00027704 / )
    Dosage: 2500 iu;qd;sc
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-07
    End date: 2011-09-30

Abbokinase
    Dosage: 100 kiu;qd
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-15
    End date: 2011-09-15

Omeprazole
    Dosage: 20 mg;qd;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-10-07

Allopurinol
    Dosage: 300 mg;qd;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-08

Enoxaparin Sodium
    Dosage: 20 mg;qd;sc
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-08-26

Meropenem
    Dosage: 1 mg;tid;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-05
    End date: 2011-09-14

Levofloxacine (Levofloxacin)
    Dosage: 500 mg;qd;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-18
    End date: 2011-09-28

Orbenin (Cloxacillin Sodium)
    Dosage: 1000 mg;qid;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-31
    End date: 2011-09-16

Duphalac
    Dosage: 10 gm;qd;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-31
    End date: 2011-09-14

Targocid
    Dosage: 400 mg;qd;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-06
    End date: 2011-09-19

Polaramine
    Dosage: 12 mg;prn;po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-16
    End date: 2011-09-22

Ambisome
    Dosage: 250 mg;qd;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-16
    End date: 2011-09-26

Noxafil
    Dosage: po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-02
    End date: 2011-09-17

Acetaminophen
    Dosage: 1 gm;tid;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-08

Furosemide
    Dosage: 20 mg;qd;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-08
    End date: 2011-09-26

Cubicin
    Dosage: 350 mg;qd;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-10
    End date: 2011-09-14

Maxipime
    Dosage: 1 gm;tid;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-08-25
    End date: 2011-09-03

Tazocel (Pip / Tazo)
    Dosage: 1 gm;qid;iv
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-14
    End date: 2011-09-19

Vesanoid
    Dosage: 50 mg;bid;po
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia
    Start date: 2011-08-26
    End date: 2011-10-07



Possible Cubicin side effects in 90 year old male

Reported by a physician from Japan on 2012-03-28

Patient: 90 year old male

Reactions: Activated Partial Thromboplastin Time Prolonged, Drug Interaction, Prothrombin Time Prolonged

Drug(s) suspected as cause:
Cubicin
    Dosage: daily dosage unknown
    Indication: Staphylococcal Infection
    Start date: 2012-01-30
    End date: 2012-01-31

Warfarin Sodium
    Dosage: daily dosage unknown
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-01-26



Possible Cubicin side effects in 12 year old female

Reported by a individual with unspecified qualification from France on 2012-03-19

Patient: 12 year old female, weighing 40.5 kg (89.1 pounds)

Reactions: Sepsis, Drug Interaction, Toxicity To Various Agents

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cubicin
    Dosage: dose unit:u unknown
    Indication: Sepsis
    Start date: 2012-01-01
    End date: 2012-01-21

Etoposide
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-11-16
    End date: 2012-01-01

Methotrexate
    Dosage: dose unit:17
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-21
    End date: 2012-01-19

Other drugs received by patient: Luride; Plitican; Zantac; Gentamicin; Zoledronoc Acid; Cyclophosphamide; Phosphorus; Ifosfamide; ALL Other Therapeutic Products; ALL Other Therapeutic Products; Zyvox; Calcium Carbonate; Piperacillin and Tazobactam; Targocid; Vancomycin; Morphine Sulfate; Atarax / 00595201 /; Mesna; Ergocalciferol; Acetaminophen; Calcium Folinate



Possible Cubicin side effects in 90 year old male

Reported by a consumer/non-health professional from United States on 2012-03-12

Patient: 90 year old male

Reactions: Activated Partial Thromboplastin Time Prolonged, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Drug Interaction, Prothrombin Time Prolonged

Drug(s) suspected as cause:
Cubicin
    Dosage: 350 mg, qd
    Indication: Staphylococcal Infection
    Start date: 2012-01-30
    End date: 2012-01-31

Warfarin Sodium
    Dosage: 2 mg, qd
    Administration route: Oral
    End date: 2012-01-26



Possible Cubicin side effects in 90 year old male

Reported by a physician from Japan on 2012-03-12

Patient: 90 year old male

Reactions: Activated Partial Thromboplastin Time Prolonged, Drug Interaction, Prothrombin Time Prolonged

Drug(s) suspected as cause:
Cubicin
    Dosage: daily dosage unknown
    Indication: Staphylococcal Infection
    Start date: 2012-01-30
    End date: 2012-01-31

Warfarin Sodium
    Dosage: daily dosage unknown
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-01-26



Possible Cubicin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-13

Patient:

Reactions: Trismus, Drug Interaction

Drug(s) suspected as cause:
Invanz
    Dosage: dose unit:u unknown
    Indication: Product Used FOR Unknown Indication

Cubicin
    Dosage: dose unit:u unknown
    Indication: Product Used FOR Unknown Indication



Possible Cubicin side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-13

Patient:

Reactions: Trismus, Drug Interaction

Drug(s) suspected as cause:
Invanz
    Dosage: dose unit:u unknown
    Indication: Product Used FOR Unknown Indication

Cubicin
    Dosage: dose unit:u unknown
    Indication: Product Used FOR Unknown Indication



Possible Cubicin side effects in 69 year old male

Reported by a physician from United States on 2011-11-11

Patient: 69 year old male, weighing 133.0 kg (292.6 pounds)

Reactions: Rhabdomyolysis, Drug Interaction, Blood Potassium Increased, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cubicin

Cubicin

Simvastatin
    Indication: Product Used FOR Unknown Indication

Cubicin

Cubicin
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Levofloxacin; Gentamicin; Vancomycin; Cefepime

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