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Cyclophosphamide (Cyclophosphamide) - Anaemia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Anaemia (235)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide where reactions include anaemia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 235   Next >>

Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient: male, weighing 94.0 kg (206.8 pounds)

Reactions: Intussusception, Anaemia, Chronic Obstructive Pulmonary Disease, Renal Failure Chronic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabthera
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-03

Fludarabine Phosphate
    Dosage: day1, 2, 3 q month
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-05

Cyclophosphamide
    Dosage: day1, 2, 3 q month
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-08-16
    End date: 2012-01-05



Possible Cyclophosphamide side effects in 65 year old female

Reported by a physician from Japan on 2012-08-24

Patient: 65 year old female, weighing 50.2 kg (110.6 pounds)

Reactions: Weight Decreased, Blood Bilirubin Increased, Cytomegalovirus Viraemia, Headache, Pyrexia, Interstitial Lung Disease, Oedema, Thrombocytopenia, Blood Sodium Decreased, Decreased Appetite, Vomiting, Stomatitis, Pneumonia, Alanine Aminotransferase Increased, Lymphopenia, Anaemia, Febrile Neutropenia, Rash, Blood Phosphorus Decreased, Blood Potassium Decreased, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Prednisolone
    Dosage: 1mg/kg x 1/2 week
    Start date: 2011-12-13
    End date: 2011-12-14

Adriamycin PFS
    Dosage: 30 mg/m2 x 1/4 week
    Start date: 2011-03-16

Prednisolone
    Dosage: 40 mg/m2 x 1/4 week
    Administration route: Oral
    Start date: 2011-03-16

Prednisolone
    Dosage: 2 mg/m2, 1x/day
    Administration route: Oral
    Start date: 2011-03-24

Vindesine Sulfate
    Dosage: 2.4 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Carboplatin
    Dosage: 250 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Cyclophosphamide
    Dosage: 350 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Etoposide
    Dosage: 100 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-24

Vincristine Sulfate
    Dosage: 1 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Ranimustine
    Dosage: 60 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-16

Adriamycin PFS
    Dosage: 40 mg/m2 x 1/4 week
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-03-09

Other drugs received by patient: Mucosolvan; Lansoprazole; Sulfamethoxazole and Trimethoprim; Armodafinil; Zolpidem; Olopatadine HCL; Cefazolin Sodium; Ciprofloxacin HCL; Armodafinil; Zovirax; Magmitt; Alendronate Sodium



Possible Cyclophosphamide side effects in 67 year old female

Reported by a physician from Netherlands on 2012-08-23

Patient: 67 year old female, weighing 46.0 kg (101.2 pounds)

Reactions: Anaemia, Circulatory Collapse

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituximab
    Dosage: 540 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-06

Cyclophosphamide
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05

Doxorubicin Hydrochloride
    Dosage: 72 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05

Neupogen
    Dosage: 6 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-06

Prednisone TAB
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05



Possible Cyclophosphamide side effects in

Reported by a physician from Japan on 2012-08-23

Patient:

Reactions: White Blood Cell Count Decreased, Stomatitis, Anaemia, Febrile Neutropenia, Constipation, Neutrophil Count Decreased

Drug(s) suspected as cause:
Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-10-27
    End date: 2010-10-28

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-12-07
    End date: 2010-12-07

Epirubicin Hydrochloride
    Dosage: |100 mg, once
    Indication: Breast Cancer
    Start date: 2010-09-29
    End date: 2010-09-29

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-12-07
    End date: 2010-12-07

Emend
    Dosage: 125 mg, once
    Administration route: Oral
    Indication: Prophylaxis of Nausea and Vomiting
    Start date: 2010-09-29
    End date: 2010-09-29

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-10-26
    End date: 2010-10-26

Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-10-26
    End date: 2010-10-26

Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-12-07
    End date: 2010-12-07

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-09-30
    End date: 2010-10-01

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-12-08
    End date: 2010-12-09

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-10-26
    End date: 2010-10-26

Emend
    Dosage: 80 mg, qd
    Administration route: Oral
    Start date: 2010-11-17
    End date: 2010-11-18

Cyclophosphamide
    Dosage: 700 mg, qd
    Start date: 2010-11-16
    End date: 2010-11-16

Emend
    Dosage: 125 mg, qd
    Administration route: Oral
    Start date: 2010-11-16
    End date: 2010-11-16

Epirubicin Hydrochloride
    Dosage: 100 mg, qd
    Start date: 2010-11-16
    End date: 2010-11-16

Cyclophosphamide
    Dosage: 700 mg, once
    Indication: Breast Cancer
    Start date: 2010-09-29
    End date: 2010-10-29

Other drugs received by patient: Granisetron Hydrochloride; Dexamethasone Sodium Phosphate; Mucosta; Decadron Phosphate; Dexamethasone Sodium Phosphate; Mucosta; Decadron Phosphate; Granisetron Hydrochloride; Mucosta; Mucosta; Granisetron Hydrochloride; Decadron Phosphate; Dexamethasone Sodium Phosphate; Granisetron Hydrochloride; Decadron Phosphate; Dexamethasone Sodium Phosphate



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma



Possible Cyclophosphamide side effects in 56 year old female

Reported by a physician from United States on 2012-08-22

Patient: 56 year old female, weighing 91.2 kg (200.6 pounds)

Reactions: Anaemia, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: 65mgm2 cyclic
    Indication: Breast Cancer
    Start date: 2011-02-03
    End date: 2011-04-13

Pazopanib
    Dosage: 400mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-02-03
    End date: 2011-04-10

Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2010-11-10
    End date: 2011-01-12

Doxorubicin Hydrochloride
    Dosage: 60mgm2 cyclic
    Indication: Breast Cancer
    Start date: 2010-11-10
    End date: 2011-01-12

Other drugs received by patient: Armodafinil



Possible Cyclophosphamide side effects in 54 year old female

Reported by a physician from United States on 2012-08-21

Patient: 54 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Anaemia, Febrile Neutropenia, Pancytopenia, Platelet Count Decreased, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 6 df, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Doxorubicin HCL
    Dosage: 60 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Paclitaxel
    Dosage: 80 mg/m2, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Bevacizumab
    Dosage: 10 mg/kg, per chemo regim
    Indication: Breast Cancer
    Start date: 2011-08-11

Cyclophosphamide
    Dosage: 600 mg/m2, unk
    Indication: Breast Cancer
    Start date: 2011-11-10

Pegfilgrastim
    Dosage: 480 mug, unk
    Indication: Chemotherapy
    Start date: 2011-12-22

Other drugs received by patient: Tylenol (Caplet); Emend; Levaquin; Decadron; Zofran / 00955302 /; Aloxi; Compazine



Possible Cyclophosphamide side effects in female

Reported by a physician from Netherlands on 2012-08-17

Patient: female, weighing 46.0 kg (101.2 pounds)

Reactions: Anaemia, Circulatory Collapse

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-05

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-06

Filgrastim
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-10-06



Possible Cyclophosphamide side effects in

Reported by a physician from United Kingdom on 2012-08-10

Patient:

Reactions: Diarrhoea, Anaemia, Dizziness, Pulmonary Mycosis, Lethargy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 2 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-04

Doxorubicin HCL
    Dosage: 100 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-04

Velcade
    Dosage: 2.6 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-04

Rituximab
    Dosage: 750 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-04

Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-04

Prednisolone
    Dosage: 100 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-07-08

Other drugs received by patient: Prednisolone; Tramadol HCL; Chlorhexidine Gluconate; Omeprazole; Itraconazole; Acyclovir; Symbicort; Montelukast; Cetraben / 01561901 /; Fluconazole; Nitrofurantoin; Citalopram Hydrobromide; NEO-Mercazole TAB; Cotrim; Ferrous Fumarate; Ventolin; Enoxaparin Sodium; Metoclopramide



Possible Cyclophosphamide side effects in 26 year old female

Reported by a physician from Japan on 2012-08-03

Patient: 26 year old female

Reactions: Enterocolitis Haemorrhagic, Cytomegalovirus Enterocolitis, Gastrointestinal Haemorrhage, Pleurisy, Anaemia, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate Sodium
    Indication: Chronic Myeloid Leukaemia

Adriamycin PFS
    Dosage: 35.2 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Oncovin
    Dosage: 1.971 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Sprycel
    Dosage: 70 mg
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-03-01

Cyclophosphamide
    Dosage: 422.4 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Other drugs received by patient: Lasix; Primperan TAB; Armodafinil; Levofloxacin; NEO-Minophagen C; Decadron Phosphate; Allopurinol



Possible Cyclophosphamide side effects in male

Reported by a pharmacist from United States on 2012-08-03

Patient: male

Reactions: Renal Failure, Anaemia, Encephalopathy, Multiple Myeloma, Hypercalcaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Multiple Myeloma

Revlimid
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-10-02

Velcade
    Indication: Multiple Myeloma

Decadron Phosphate
    Indication: Multiple Myeloma

Other drugs received by patient: Hydrocodone Bitartrate; Vitamins NOS; Prochlorperazine; Tamsulosin HCL; Venlafaxine; Aspirin; Miralax; Ibuprofen (Advil); Magnesium Oxide; Omeprazole; Oxycontin; Trazodone Hydrochloride; Finasteride



Possible Cyclophosphamide side effects in female

Reported by a physician from Poland on 2012-08-02

Patient: female, weighing 58.0 kg (127.6 pounds)

Reactions: Retroperitoneal Mass, Vomiting, Nausea, Anaemia, Nephropathy Toxic, Folate Deficiency, Iron Deficiency, Herpes Zoster, Vitamin B12 Increased, Asthenia, Beta 2 Microglobulin Increased, Leukopenia

Drug(s) suspected as cause:
Vincristine
    Indication: Lymphoma
    Start date: 2011-06-22
    End date: 2011-10-27

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-06-22
    End date: 2011-10-27

Prednisone
    Administration route: Oral
    Indication: Lymphoma
    Start date: 2011-06-22
    End date: 2011-10-27

Cyclophosphamide
    Indication: Lymphoma
    Start date: 2011-06-22
    End date: 2011-10-27

Doxorubicin Hydrochloride
    Indication: Lymphoma
    Start date: 2011-06-22
    End date: 2011-10-27

Other drugs received by patient: Heviran; Tamoxifen Citrate



Possible Cyclophosphamide side effects in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-30

Patient: 70 year old female

Reactions: Renal Impairment, Hyperkalaemia, Anaemia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Indication: Multiple Myeloma
    Start date: 2010-09-24
    End date: 2010-11-03

Revlimid
    Dosage: 10 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2010-09-24
    End date: 2010-11-03

Cyclophosphamide
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2010-09-24
    End date: 2010-11-03



Possible Cyclophosphamide side effects in 24 year old female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: 24 year old female, weighing 51.0 kg (112.2 pounds)

Reactions: Abdominal Pain, Hyperkalaemia, Disseminated Intravascular Coagulation, Gastrointestinal Necrosis, Acidosis, Nephrolithiasis, Skin Discolouration, Ecchymosis, Clostridial Infection, Emphysema, White Blood Cell Count Decreased, Hypotension, Anaemia, Condition Aggravated, Soft Tissue Infection, Sepsis, Flank Pain, Colitis, Cardiac Arrest, Sinus Tachycardia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Sprycel
    Dosage: last dose on 26jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cytarabine
    Dosage: last dose:17jun12 route:intra ommya
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Vincristine Sulfate
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Filgrastim
    Dosage: last dose:18jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17
    End date: 2012-01-01

Leucovorin Calcium
    Dosage: last dose :21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methotrexate
    Dosage: last dose:13jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Dexamethasone
    Dosage: last dose:16jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Doxorubicin HCL
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Mesna
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cyclophosphamide
    Dosage: last dose on 16jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methylprednisolone
    Dosage: last dose:21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17



Possible Cyclophosphamide side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient: 46 year old female

Reactions: Pain in Extremity, Unresponsive To Stimuli, Anaemia, Pallor, Pulmonary Haemorrhage, Zygomycosis, Skin Discolouration, Diarrhoea Haemorrhagic, Blood Culture Positive, Small Intestinal Haemorrhage, Asthenia, Apnoea, Hepatosplenomegaly, Candidiasis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Oncovin
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide

Idarubicin HCL
    Dosage: 12 mg/d/m2 (1 cycle)

Rituximab
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Melphalan Hydrochloride

Vorinostat
    Dosage: 1 cycle
    Administration route: Oral

Cyclophosphamide
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine

Rituximab

Carmustine

Cytarabine
    Dosage: 1.5 g/d/m2 (1 cycle)



Possible Cyclophosphamide side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient: 46 year old female

Reactions: Pain in Extremity, Anaemia, Pyrexia, Pallor, Stem Cell Transplant, Pulmonary Haemorrhage, Zygomycosis, Skin Discolouration, Blood Culture Positive, Diarrhoea Haemorrhagic, Small Intestinal Haemorrhage, Asthenia, Hepatosplenomegaly, Candidiasis, Cough

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Carmustine

Idarubicin HCL
    Dosage: 12 mg/d/m2 (1 cycle)

Rituximab
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine

Melphalan Hydrochloride

Cytarabine
    Dosage: 1.5 g/d/m2 (1 cycle)

Oncovin
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide

Rituximab

Doxorubicin Hydrochloride
    Dosage: 8 courses
    Indication: Diffuse Large B-Cell Lymphoma

Vorinostat
    Dosage: 1 cycle
    Administration route: Oral



Possible Cyclophosphamide side effects in 46 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-27

Patient: 46 year old female

Reactions: Pancreatic Infarction, Unresponsive To Stimuli, Myelodysplastic Syndrome, Pyrexia, Pallor, Cerebral Haemorrhage, Skin Discolouration, Diarrhoea Haemorrhagic, Small Intestinal Haemorrhage, Apnoea, Thrombocytopenia, Cough, Candidiasis, Hepatosplenomegaly, Dyspnoea, Pain in Extremity, Anaemia, Pulmonary Haemorrhage, Zygomycosis, Diarrhoea, Hemisensory Neglect, Lung Infiltration, Asthenia, Hepatic Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Idarubicin HCL
    Dosage: 12 mg/m2, unk
    Indication: Myelodysplastic Syndrome

Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Suberoylanilide Hydroxamic Acid
    Dosage: 500 mg, tid
    Administration route: Oral
    Indication: Myelodysplastic Syndrome

Cytarabine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Oncovin
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Radiotherapy



Possible Cyclophosphamide side effects in 26 year old female

Reported by a physician from Japan on 2012-07-27

Patient: 26 year old female

Reactions: Enterocolitis Haemorrhagic, Cytomegalovirus Enterocolitis, Gastrointestinal Haemorrhage, Pleurisy, Anaemia, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 422.4 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Adriamycin PFS
    Dosage: 35.2 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Methotrexate Sodium
    Dosage: unk
    Indication: Chronic Myeloid Leukaemia

Sprycel
    Dosage: 70 mg, 2x/day
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-03-01
    End date: 2010-08-04

Oncovin
    Dosage: 1.971 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Other drugs received by patient: NEO-Minophagen C; Decadron; Primperan TAB; Diflucan; Allopurinol; Lasix; Levofloxacin



Possible Cyclophosphamide side effects in

Reported by a physician from Italy on 2012-07-27

Patient:

Reactions: Anaemia, Skin Toxicity, Febrile Neutropenia, Mucosal Inflammation, Neurotoxicity, Respiratory Failure, Sepsis, Neutropenia, Cardiotoxicity, Septic Shock, Thrombocytopenia, Myocardial Infarction, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Epirubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone and Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in female

Reported by a physician from United Kingdom on 2012-07-27

Patient: female, weighing 53.0 kg (116.6 pounds)

Reactions: Anaemia, Neutropenia, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Prednisone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Furosemide

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23



Possible Cyclophosphamide side effects in 26 year old female

Reported by a physician from Japan on 2012-07-24

Patient: 26 year old female

Reactions: Enterocolitis Haemorrhagic, Gastrointestinal Haemorrhage, Cytomegalovirus Enterocolitis, Pleurisy, Anaemia, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 422.4 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Adriamycin PFS
    Dosage: 35.2 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Methotrexate Sodium
    Dosage: unk
    Indication: Chronic Myeloid Leukaemia

Sprycel
    Dosage: 70 mg, 2x/day
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-03-01
    End date: 2010-08-04

Oncovin
    Dosage: 1.971 mg/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Other drugs received by patient: Decadron; Diflucan; Allopurinol; Levofloxacin; Lasix; Primperan TAB; NEO-Minophagen C



Possible Cyclophosphamide side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-23

Patient: female, weighing 67.0 kg (147.4 pounds)

Reactions: Small Intestinal Obstruction, Anaemia, Febrile Neutropenia, Device Related Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Start date: 2012-04-26

Cyclophosphamide
    Start date: 2012-04-26

Prednisolone
    Administration route: Oral
    Start date: 2012-04-26

Vincristine
    Start date: 2012-04-26



Possible Cyclophosphamide side effects in

Reported by a physician from Italy on 2012-07-20

Patient:

Reactions: Anaemia, Febrile Neutropenia, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Mucosal Inflammation, Neurotoxicity, Sepsis, Adverse Event, Cardiotoxicity, Neutropenia, Thrombocytopenia, Diffuse Large B-Cell Lymphoma, Lymphoma, Septic Shock

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2 on day 1 for chop and 750 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: 50 mg/m2 on day 1 for chop and 50 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 375 mg/m2 on day 1 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: 1.4 mg/m2 on day 1 for chop and 1.4 mg/m2 on day 2 for r-chop upto a maximum dose of 2 mg
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 100 mg on days 1-5 for chop and r-chop
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Neupogen



Possible Cyclophosphamide side effects in 26 year old female

Reported by a physician from Japan on 2012-07-19

Patient: 26 year old female

Reactions: Enterocolitis Haemorrhagic, Cytomegalovirus Enterocolitis, Gastrointestinal Haemorrhage, Anaemia, Pleurisy, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 35.2 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Sprycel
    Dosage: 70 mg
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-03-01

Methotrexate Sodium
    Indication: Chronic Myeloid Leukaemia

Cyclophosphamide
    Dosage: 422.4 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Oncovin
    Dosage: 1.971 mg, 1x/day
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Other drugs received by patient: Decadron; Allopurinol; Primperan TAB; Lasix; Levofloxacin; NEO-Minophagen C; Diflucan



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-18

Patient:

Reactions: Pneumonia, Nausea, Lymphopenia, Hyperglycaemia, Anaemia, Febrile Neutropenia, Constipation, Renal Failure, Neuropathy Peripheral, Fatigue, Diarrhoea, Embolism, Neutropenia, Thrombocytopenia, Deep Vein Thrombosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Velcade
    Dosage: 1.3 milligram/sq. meter
    Indication: Multiple Myeloma

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma

Revlimid
    Dosage: 15 milligram
    Administration route: Oral

Cyclophosphamide
    Dosage: 500 milligram/sq. meter
    Indication: Multiple Myeloma

Velcade
    Dosage: 1.3 milligram/sq. meter

Dexamethasone
    Dosage: 40 milligram
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in 69 year old female

Reported by a pharmacist from Switzerland on 2012-07-16

Patient: 69 year old female

Reactions: Interstitial Lung Disease, Anaemia, Lymphopenia, Neutrophil Count Decreased, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-01-01
    End date: 2012-03-01

Taxol
    Start date: 2012-01-02
    End date: 2012-05-10

Epirubicin Hydrochloride
    Start date: 2012-01-01
    End date: 2012-03-01

Herceptin
    Start date: 2012-01-02
    End date: 2012-05-10

Other drugs received by patient: Piracetam; Phlebostasin; Betaserc; Amlodipine



Possible Cyclophosphamide side effects in 68 year old female

Reported by a pharmacist from Switzerland on 2012-07-09

Patient: 68 year old female

Reactions: Interstitial Lung Disease, Anaemia, Lymphopenia, Neutrophil Count Decreased, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxol
    Dosage: unk
    Indication: Breast Cancer in Situ
    Start date: 2012-01-02
    End date: 2012-03-01

Cyclophosphamide
    Dosage: 900 mg, cyclic
    Indication: Breast Cancer in Situ
    Start date: 2012-01-01
    End date: 2012-03-01

Taxol
    Dosage: 120 mg, weekly
    Start date: 2012-03-29
    End date: 2012-05-10

Herceptin
    Dosage: unk
    Indication: Breast Cancer in Situ
    Start date: 2012-01-02
    End date: 2012-03-01

Herceptin
    Dosage: 240 mg, 1x/day
    Start date: 2012-03-29
    End date: 2012-03-29

Herceptin
    Dosage: 120 mg, weekly
    Start date: 2012-04-05
    End date: 2012-05-10

Epirubicin Hydrochloride
    Dosage: 135 mg, cyclic
    Indication: Breast Cancer in Situ
    Start date: 2012-01-01
    End date: 2012-03-01

Other drugs received by patient: Betaserc; Fragmin; Phlebostasin; Pantoprazole Sodium; Betaserc; Nootropil; Phlebostasin; Pantoprazole Sodium; Nootropil; Amlodipin Mepha



Possible Cyclophosphamide side effects in male

Reported by a consumer/non-health professional from Germany on 2012-07-09

Patient: male

Reactions: Anaemia, Febrile Neutropenia, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 100 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-04-03

Vincristine
    Dosage: 2 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-04-03

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-06
    End date: 2012-04-06

Rituximab
    Dosage: 750 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-02
    End date: 2012-04-02

Cyclophosphamide
    Dosage: 1500 mg, qd
    Indication: B-Cell Lymphoma
    Start date: 2012-04-03
    End date: 2012-04-03

Prednisolone
    Dosage: 500 mg, qd
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-04-02
    End date: 2012-04-06

Other drugs received by patient: Novalgin / 00169801 /; Morphine Sulfate; Pantoprazole; Dipyrone TAB; Metoclopramide; Acyclovir



Possible Cyclophosphamide side effects in female

Reported by a consumer/non-health professional from Germany on 2012-07-06

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: B-Cell Lymphoma, Anaemia, Urinary Incontinence, Abnormal Behaviour, Pulmonary Embolism, Cognitive Disorder, Pyrexia, Fall, Peripheral Sensory Neuropathy, Post Transplant Lymphoproliferative Disorder, Klebsiella Infection, Cytokine Release Syndrome, Cytomegalovirus Infection, Neutrophil Toxic Granulation Present, Traumatic Haematoma, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: 30 mg, bid
    Start date: 2009-07-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-07

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-06-23

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-06-23

Filgrastim
    Dosage: 3000 iu, unk
    Start date: 2009-07-26
    End date: 2009-08-27

Campath
    Dosage: 20 mg, qd
    Start date: 2009-07-07

Vincristine
    Dosage: 1 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-15

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-08-20

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-09-11

Campath
    Dosage: 30 mg, qd
    Start date: 2009-08-06
    End date: 2009-08-06

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-21

Doxorubicin HCL
    Dosage: 80 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-07-07

Filgrastim
    Dosage: unk on days 4 through 13 of course 5
    Start date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-21

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-15

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-08-06
    End date: 2009-08-10

Filgrastim
    Dosage: unk on days 4 through 12 of course 6
    Start date: 2009-09-08

Campath
    Dosage: 30 mg, qd
    Start date: 2009-09-11
    End date: 2009-10-22

Cyclophosphamide
    Dosage: 1250 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-09-08
    End date: 2009-09-08

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-09-08
    End date: 2009-09-08

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-23

Filgrastim
    Dosage: unk on days 4, 5, 6 of course 1
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Filgrastim
    Dosage: unk on days 4 through 15 of course 2
    Start date: 2009-07-07

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-23

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-07

Filgrastim
    Dosage: unk on days 4 through 8 and day 13 of course 3
    Start date: 2009-07-23

Filgrastim
    Dosage: unk on days 6 + 7 and days 9 through 12 of course 4
    Start date: 2009-08-06

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-08-20

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-21

Vincristine

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-07-23

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Start date: 2009-09-08
    End date: 2009-09-08

Campath
    Dosage: 10 mg, qd
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-07

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Filgrastim
    Dosage: 30000 iu, qd
    Start date: 2009-09-11
    End date: 2009-09-19

Other drugs received by patient: Enoxaparin Sodium; Enoxaparin Sodium; Ganciclovir; Metoprolol Tartrate; Trimethoprim + Sulfamethoxazole; Dexamethasone; Antibiotics; Torsemide; Fluticasone Propionate W; Fondaparinux Sodium; Pantoprazole; Ganciclovir; Spiriva



Possible Cyclophosphamide side effects in 60 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-06

Patient: 60 year old male

Reactions: Anaemia, Glucocorticoid Deficiency, Constipation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Thalidomide
    Dosage: 50 milligram
    Administration route: Oral
    Start date: 2012-05-01

Dexamethasone Sodium Phosphate
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-23

Cyclophosphamide
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-23

Thalidomide
    Dosage: 100 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-04-23

Other drugs received by patient: Ondansetron; Morphine



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