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Cyclophosphamide (Cyclophosphamide) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Death (204)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Cyclophosphamide where reactions include death. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 204   Next >>

Possible Cyclophosphamide side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: male, weighing 103.1 kg (226.8 pounds)

Reactions: Plasmacytosis, Pneumonia, Mouth Haemorrhage, Pseudomonas Infection, Headache, Disease Progression, Death, Mucosal Inflammation, Pleural Effusion, Depressed Level of Consciousness, Abscess, Lethargy, RIB Fracture

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Doxorubicin Hydrochloride
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Radiation Therapy NOS
    Indication: Multiple Myeloma

Revlimid
    Indication: Multiple Myeloma

Thalidomide
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma

Other drugs received by patient: Bendamustine Hydrochloride; Lenalidomide



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-23

Patient: male

Reactions: Death, Chalazion

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Lenalidomide
    Indication: Multiple Myeloma

Velcade
    Dosage: 2 mg, 1/week
    Indication: Multiple Myeloma
    Start date: 2009-08-13
    End date: 2012-01-03

Other drugs received by patient: Bisphosphonates; Travoprost



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-20

Patient:

Reactions: Death, Lymphoma, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Cyclophosphamide side effects in 35 year old female

Reported by a physician from Philippines on 2012-08-16

Patient: 35 year old female, weighing 56.2 kg (123.6 pounds)

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: form:vialtotal dose recieved:936 mg
    Start date: 2010-11-04

Docetaxel
    Dosage: form:vialtotal dose recieved:152 mg
    Start date: 2010-09-02

Epirubicin
    Dosage: form:vialtotal dose recieved:140 mg
    Start date: 2010-11-04

Fluorouracil
    Dosage: form:vial
    Start date: 2010-11-04

Trastuzumab
    Dosage: form:vialtotal dose recieved:336 mg
    Start date: 2011-07-21

Trastuzumab
    Dosage: form:vial



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-13

Patient:

Reactions: Pulmonary Embolism, Multiple Myeloma, Peripheral Sensory Neuropathy, Constipation, Somnolence, Death, Complications of Transplant Surgery, Peripheral Motor Neuropathy, Thrombosis in Device, Blood Alkaline Phosphatase Increased, Pancytopenia, Multiple Fractures, Rash, Renal Failure, Osteonecrosis of JAW, Embolism, Hypothyroidism, Deep Vein Thrombosis, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: 40 milligram
    Administration route: Oral

Dexamethasone
    Dosage: 20 milligram
    Indication: Multiple Myeloma

Thalidomide
    Dosage: or 4 weeks and increased every 4 weeks in 50-mg increments to a maximum of 200mg/day
    Administration route: Oral
    Indication: Multiple Myeloma

Other drugs received by patient: Melphalan Hydrochloride; Prednisolone; CLO; ZOL; Melphalan Hydrochloride; Biphosphonate; Vincristine; Doxorubicin Hydrochloride; Bortezomib



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-13

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin
    Dosage: days 1 and 5
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: day 1

Doxorubicin HCL
    Dosage: day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: day 1

Prednisone TAB
    Dosage: days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: day 1
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: day 1
    Indication: Diffuse Large B-Cell Lymphoma

Vindesine
    Dosage: days 1 and 5
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Fluorodeoxyglucose F 18



Possible Cyclophosphamide side effects in female

Reported by a physician from Philippines on 2012-08-13

Patient: female, weighing 56.2 kg (123.6 pounds)

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2010-11-04

Docetaxel
    Indication: Breast Cancer
    Start date: 2010-09-02

Epirubicin Hydrochloride
    Indication: Breast Cancer
    Start date: 2010-11-04

Fluorouracil
    Indication: Breast Cancer
    Start date: 2010-11-04

Herceptin
    Indication: Breast Cancer
    Start date: 2011-07-21

Herceptin



Possible Cyclophosphamide side effects in 35 year old female

Reported by a physician from Philippines on 2012-08-09

Patient: 35 year old female, weighing 56.2 kg (123.6 pounds)

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: form:vialtotal dose recieved:936 mg
    Start date: 2010-11-04

Docetaxel
    Dosage: form:vialtotal dose recieved:152 mg
    Start date: 2010-09-02

Epirubicin
    Dosage: form:vialtotal dose recieved:140 mg
    Start date: 2010-11-04

Fluorouracil
    Dosage: form:vial
    Start date: 2010-11-04

Trastuzumab
    Dosage: form:vial

Trastuzumab
    Dosage: form:vialtotal dose recieved:336 mg
    Start date: 2011-07-21



Possible Cyclophosphamide side effects in

Reported by a physician from Israel on 2012-08-08

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Multiple Myeloma

Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Thalidomide
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-08-07

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone TAB
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in male

Reported by a physician from United States on 2012-08-07

Patient: male, weighing 73.1 kg (160.8 pounds)

Reactions: Death

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 743 mg
    End date: 2012-07-24

Doxorubicin Hydrochloride
    Dosage: 79.2 mg
    End date: 2012-07-24

Etoposide
    Dosage: 396 mg
    End date: 2012-07-24

Prednisone TAB
    Dosage: 600 mg
    End date: 2012-07-24

Other drugs received by patient: Vincristine Sulfate; Rituximab (Moab C2b8 Anti Cd20, Chimeric)



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-08-07

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone TAB
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-08-07

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone TAB
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-08-07

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Dosage: unk
    Indication: Multiple Myeloma

Cyclophosphamide
    Dosage: unk
    Indication: Multiple Myeloma

Etoposide
    Dosage: unk
    Indication: Multiple Myeloma

Prednisone TAB
    Dosage: unk
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-08-07

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone TAB
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from Spain on 2012-08-06

Patient:

Reactions: Skin Toxicity, Sudden Death, Hepatic Failure, Encephalitis, Cytomegalovirus Colitis, Pneumonia Pneumococcal, Neurotoxicity, Death, Multi-Organ Failure, Metastasis, Cardiotoxicity, AIDS Dementia Complex, Pseudomonas Infection, Toxicity To Various Agents, Staphylococcal Infection, Pneumonia Herpes Viral, Neutropenia, Escherichia Infection, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: given on day 1 of the 3 week cycle
    Indication: Lymphoma AIDS Related

Doxorubicin HCL
    Dosage: given on day 1 of the 3 week cycle
    Indication: Lymphoma AIDS Related

Mabthera
    Dosage: given on day 1 of every 3 week cycle (prior to chop)
    Indication: Lymphoma AIDS Related

Prednisone TAB
    Dosage: given for 5 days
    Administration route: Oral
    Indication: Lymphoma AIDS Related

Vincristine Sulfate
    Dosage: given on day 1 of 3 week cycle.
    Indication: Lymphoma AIDS Related

Other drugs received by patient: Hydrocortisone; Cytarabine; Methotrexate



Possible Cyclophosphamide side effects in female

Reported by a physician from Philippines on 2012-08-01

Patient: female, weighing 56.2 kg (123.6 pounds)

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2010-11-04

Docetaxel
    Indication: Breast Cancer
    Start date: 2010-09-02

Epirubicin Hydrochloride
    Indication: Breast Cancer
    Start date: 2010-11-04

Fluorouracil
    Indication: Breast Cancer
    Start date: 2010-11-04

Herceptin
    Indication: Breast Cancer
    Start date: 2011-07-21

Herceptin



Possible Cyclophosphamide side effects in 57 year old female

Reported by a pharmacist from Japan on 2012-07-27

Patient: 57 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 500 mg/m2, 1x/day
    Indication: Breast Cancer
    Start date: 2012-07-16

Epirubicin Hydrochloride
    Dosage: 70 mg/m2, 1x/day
    Indication: Breast Cancer
    Start date: 2012-07-16

Fluorouracil
    Dosage: 500 mg/m2, 1x/day
    Indication: Breast Cancer
    Start date: 2012-07-16



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-07-25

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-07-25

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-07-25

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-07-25

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a physician from China on 2012-07-25

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Prednisone
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in 53 year old male

Reported by a physician from United States on 2012-07-23

Patient: 53 year old male, weighing 61.6 kg (135.5 pounds)

Reactions: Death, Optic Nerve Disorder, Neuropathy Peripheral, Palmar-Plantar Erythrodysaesthesia Syndrome, Blindness, Progressive Multifocal Leukoencephalopathy, Peripheral Motor Neuropathy

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: cycle 1
    Indication: Lymphoma AIDS Related
    Start date: 2008-04-08
    End date: 2008-04-08

Cyclophosphamide
    Dosage: cycle 6-1222mg in total
    Start date: 2008-09-04
    End date: 2008-09-04

Doxorubicin Hydrochloride
    Dosage: on day 1
    Indication: Lymphoma AIDS Related
    Start date: 2008-04-08
    End date: 2008-04-08

Doxorubicin Hydrochloride
    Dosage: 6th cycle-49 mg in total
    Start date: 2008-09-04
    End date: 2008-09-04

Prednisone
    Dosage: cycle 6- 500mg total
    Administration route: Oral
    Start date: 2008-09-04
    End date: 2008-09-08

Prednisone
    Dosage: days 1-5
    Administration route: Oral
    Indication: Lymphoma AIDS Related
    Start date: 2008-04-08
    End date: 2008-04-12

Rituximab
    Dosage: cycle 6 - 611mg in total
    Start date: 2008-09-04
    End date: 2008-09-04

Rituximab
    Dosage: cycle 1
    Indication: Lymphoma AIDS Related
    Start date: 2008-04-08
    End date: 2008-04-08

Vincristine
    Dosage: not more than 2 mg
    Start date: 2008-04-08
    End date: 2008-04-08

Vincristine
    Dosage: cycle 6-2mg in total
    Indication: Lymphoma AIDS Related
    Start date: 2008-09-04
    End date: 2008-09-04

Other drugs received by patient: Pegfilgrastim; Neupogen; Neupogen; Unknown Medication



Possible Cyclophosphamide side effects in

Reported by a physician from France on 2012-07-18

Patient:

Reactions: Death, Lung Infection, Myocardial Infarction

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 75 mg/m2, unk
    Indication: Multiple Myeloma
    Start date: 2011-11-04
    End date: 2012-02-07

Dexamethasone
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-11-04
    End date: 2012-02-07

Velcade
    Dosage: 2.4 mg, unk
    Indication: Multiple Myeloma
    End date: 2012-02-07

Other drugs received by patient: Bisoprolol Fumarate; Clopidogrel; Ezetimibe; Perindopril Erbumine; Lercanidipine; Plavix; Acetaminophen; Codeine Phosphate and Acetaminophen



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-07-16

Patient:

Reactions: Graft Versus Host Disease, Pulmonary Embolism, Toxicity To Various Agents, Polyneuropathy, Disease Progression, Death, Embolism Venous, Deep Vein Thrombosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 15 milligram/sq. meter

Adriamycin PFS
    Dosage: 9 milligram/sq. meter
    Indication: Multiple Myeloma

Cyclophosphamide
    Dosage: 1000 milligram/sq. meter
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: 40 milligram
    Administration route: Oral

Dexamethasone
    Dosage: 40 milligram
    Administration route: Oral
    Indication: Multiple Myeloma

Melphalan Hydrochloride
    Dosage: 200 milligram/sq. meter

Thalomid
    Dosage: induction therapy, 200 mg escalated to 400 mg, qd, with vte prophylaxis
    Administration route: Oral
    Indication: Multiple Myeloma

Thalomid
    Dosage: maintenance therapy, 50 mg qd, without vte prophylaxis
    Administration route: Oral

Other drugs received by patient: Neupogen; Mycophenolate Mophetil; Cyclosporine; Nadroparine



Possible Cyclophosphamide side effects in

Reported by a physician from France on 2012-07-09

Patient:

Reactions: Death, Lung Infection, Myocardial Infarction

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 75 mg/m2, unk
    Indication: Multiple Myeloma
    Start date: 2011-11-04
    End date: 2012-04-01

Dexamethasone
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-11-04
    End date: 2012-04-01

Velcade
    Dosage: 2.4 mg, unk
    Indication: Multiple Myeloma
    End date: 2012-04-01

Other drugs received by patient: Codeine Phosphate and Acetaminophen; Lercanidipine; Perindopril Erbumine; Acetaminophen; Clopidogrel; Plavix; Ezetimibe; Bisoprolol Fumarate



Possible Cyclophosphamide side effects in

Reported by a physician from Israel on 2012-07-05

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Multiple Myeloma

Cisplatin
    Indication: Multiple Myeloma

Cyclophosphamide
    Indication: Multiple Myeloma

Dexamethasone Sodium Phosphate
    Indication: Multiple Myeloma

Etoposide
    Indication: Multiple Myeloma

Thalidomide
    Indication: Multiple Myeloma

Velcade
    Indication: Multiple Myeloma



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Indication: Acute Lymphocytic Leukaemia

Idarubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Mercaptopurine
    Indication: Acute Lymphocytic Leukaemia

Prednisone TAB
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Cyclophosphamide side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Indication: Acute Lymphocytic Leukaemia

Idarubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Mercaptopurine
    Indication: Acute Lymphocytic Leukaemia

Prednisone
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



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