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Fluconazole (Fluconazole) - Hepatotoxicity - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hepatotoxicity (34)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Fluconazole where reactions include hepatotoxicity. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 34   Next >>

Possible Fluconazole side effects in

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-09

Patient:

Reactions: Death, Hepatotoxicity, Nephropathy Toxic, Treatment Failure, Hypokalaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Itraconazole
    Indication: Systemic Candida

Fluconazole
    Indication: Systemic Candida



Possible Fluconazole side effects in 35 year old female

Reported by a physician from Germany on 2012-03-15

Patient: 35 year old female

Reactions: Blood Bilirubin Increased, Death, Hepatotoxicity, Cystitis Haemorrhagic, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Thymoglobulin
    Indication: Bone Marrow Conditioning Regimen

Acyclovir
    Indication: Antiviral Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 28 year old male

Reported by a physician from Germany on 2012-03-15

Patient: 28 year old male

Reactions: Death, Blood Bilirubin Increased, Staphylococcal Infection, Hepatotoxicity, Palmar-Plantar Erythrodysaesthesia Syndrome, Cerebral Haemorrhage

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Cytarabine
    Indication: Chemotherapy

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Acyclovir
    Indication: Antiviral Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 67 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 67 year old male

Reactions: Death, Hepatotoxicity, Nausea, Staphylococcal Infection, Oedema

Adverse event resulted in: death

Drug(s) suspected as cause:
Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Thymoglobulin
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Metronidazole
    Indication: Antibiotic Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease



Possible Fluconazole side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 52 year old male

Reactions: Blood Bilirubin Increased, Vomiting, Hepatotoxicity, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Streptococcal Sepsis, Decreased Appetite

Drug(s) suspected as cause:
Clofarabine
    Indication: Chemotherapy

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Levofloxacin
    Indication: Antibiotic Prophylaxis

Metronidazole
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cytarabine
    Indication: Chemotherapy

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Fluconazole
    Indication: Antifungal Prophylaxis



Possible Fluconazole side effects in 58 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 58 year old male

Reactions: Blood Bilirubin Increased, Mucosal Inflammation, Hepatotoxicity, Cystitis Haemorrhagic, Oedema

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Metronidazole
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen



Possible Fluconazole side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 58 year old female

Reactions: Death, Staphylococcal Infection, Hepatotoxicity, Oedema

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Thymoglobulin
    Indication: Bone Marrow Conditioning Regimen

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Levofloxacin
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 39 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 39 year old female

Reactions: Mucosal Inflammation, Vomiting, Nausea, Hepatotoxicity, Oedema, Pyrexia, Decreased Appetite

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Acyclovir
    Indication: Antiviral Prophylaxis

Cytarabine
    Indication: Chemotherapy

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 42 year old male

Reported by a physician from Germany on 2012-03-15

Patient: 42 year old male

Reactions: Death, Blood Bilirubin Increased, Mucosal Inflammation, Hepatotoxicity, Staphylococcal Infection, Skin Toxicity

Adverse event resulted in: death

Drug(s) suspected as cause:
Cytarabine
    Indication: Chemotherapy

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antifungal Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Fluconazole
    Indication: Antifungal Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease



Possible Fluconazole side effects in 19 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 19 year old male

Reactions: Blood Bilirubin Increased, Vomiting, Nausea, Cystitis Haemorrhagic, Nephropathy Toxic, Palmar-Plantar Erythrodysaesthesia Syndrome, Mucosal Inflammation, Death, Hepatotoxicity, Oedema, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Rabbit Antithymoctye Globulin
    Indication: Bone Marrow Conditioning Regimen

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 39 year old male

Reported by a physician from Germany on 2012-03-15

Patient: 39 year old male

Reactions: Mucosal Inflammation, Pneumonia, Vomiting, Nausea, Hepatotoxicity, Oedema, Pyrexia, Decreased Appetite

Drug(s) suspected as cause:
Fluconazole
    Indication: Antifungal Prophylaxis

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Cytarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Metronidazole
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Clofarabine
    Indication: Chemotherapy

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease



Possible Fluconazole side effects in 59 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 59 year old male

Reactions: Hepatotoxicity, Oedema, Palmar-Plantar Erythrodysaesthesia Syndrome, Pyrexia

Drug(s) suspected as cause:
Acyclovir
    Indication: Antiviral Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease



Possible Fluconazole side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 64 year old male

Reactions: Blood Bilirubin Increased, Vomiting, Nausea, Skin Toxicity, Candida Sepsis, Death, Hepatotoxicity, Oedema

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Acyclovir
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 62 year old male

Reactions: Death, Blood Bilirubin Increased, Hepatotoxicity, Nephropathy Toxic, Oedema, Palmar-Plantar Erythrodysaesthesia Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Cytarabine
    Indication: Chemotherapy

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Levofloxacin
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Clofarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 55 year old female

Reported by a physician from Germany on 2012-03-15

Patient: 55 year old female

Reactions: Mucosal Inflammation, Blood Bilirubin Increased, Hepatotoxicity, Pyrexia

Drug(s) suspected as cause:
Cytarabine
    Indication: Chemotherapy

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease



Possible Fluconazole side effects in 69 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 69 year old female

Reactions: Blood Bilirubin Increased, Death, Hepatotoxicity, Oedema, Palmar-Plantar Erythrodysaesthesia Syndrome, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Cytarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis



Possible Fluconazole side effects in 69 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 69 year old male

Reactions: Death, Blood Bilirubin Increased, Hepatotoxicity, Nausea, Atrial Flutter, Sepsis, Palmar-Plantar Erythrodysaesthesia Syndrome, Atrial Fibrillation, Myocardial Infarction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Cytarabine
    Indication: Chemotherapy

Acyclovir
    Indication: Antiviral Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen



Possible Fluconazole side effects in 33 year old male

Reported by a physician from Germany on 2012-03-15

Patient: 33 year old male

Reactions: Blood Bilirubin Increased, Death, Hepatotoxicity, Nausea, Oedema, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Acyclovir
    Indication: Antiviral Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Thymoglobulin
    Indication: Bone Marrow Conditioning Regimen

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Metronidazole
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Cytarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 50 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-15

Patient: 50 year old female

Reactions: Mucosal Inflammation, Blood Bilirubin Increased, Hepatotoxicity, Herpes Simplex Ophthalmic, Oedema, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Cytarabine
    Indication: Chemotherapy

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Clofarabine
    Indication: Chemotherapy

Rabbit Antithymocyte Globulin
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 39 year old male

Reported by a physician from Germany on 2012-03-15

Patient: 39 year old male

Reactions: Vomiting, Nausea, Hepatotoxicity, Oedema, Pyrexia, Decreased Appetite

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Fluconazole
    Indication: Antifungal Prophylaxis

Thymoglobulin
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Cytarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-14

Patient: 61 year old male

Reactions: Vomiting, Atrial Flutter, Nausea, Hepatotoxicity, Atrial Fibrillation, Oedema, Device Related Infection, Decreased Appetite

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis

Cytarabine
    Indication: Chemotherapy

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Clofarabine
    Indication: Chemotherapy

Acyclovir
    Indication: Antiviral Prophylaxis



Possible Fluconazole side effects in 59 year old female

Reported by a physician from Germany on 2012-03-14

Patient: 59 year old female

Reactions: Mucosal Inflammation, Death, Blood Bilirubin Increased, Hepatotoxicity, Skin Toxicity, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Cytarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 66 year old male

Reported by a physician from Germany on 2012-03-14

Patient: 66 year old male

Reactions: Blood Bilirubin Increased, Pneumonia, Hepatotoxicity

Drug(s) suspected as cause:
Metronidazole
    Indication: Antibiotic Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Levofloxacin
    Indication: Antibiotic Prophylaxis

Acyclovir
    Indication: Antiviral Prophylaxis

Fluconazole
    Indication: Antifungal Prophylaxis

Cytarabine
    Indication: Chemotherapy

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Clofarabine
    Indication: Chemotherapy



Possible Fluconazole side effects in 69 year old male

Reported by a physician from Germany on 2012-03-14

Patient: 69 year old male

Reactions: Blood Bilirubin Increased, Mucosal Inflammation, Multi-Organ Failure, Venoocclusive Disease, Hepatotoxicity, Skin Toxicity, Sepsis, Oedema, Pyrexia

Adverse event resulted in: death

Drug(s) suspected as cause:
Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cytarabine
    Indication: Chemotherapy

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-14

Patient: 65 year old male

Reactions: Blood Bilirubin Increased, Staphylococcal Infection, Hepatotoxicity, Nausea, Skin Toxicity, Oedema

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Fluconazole
    Indication: Antifungal Prophylaxis

Cytarabine
    Indication: Chemotherapy

Metronidazole
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Acyclovir
    Indication: Antiviral Prophylaxis

Levofloxacin
    Indication: Antibiotic Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Clofarabine
    Indication: Chemotherapy

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen



Possible Fluconazole side effects in 60 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-12

Patient: 60 year old male

Reactions: Blood Bilirubin Increased, Vomiting, Pneumonia, Nausea, Skin Toxicity, Pyrexia, Death, Hepatotoxicity, Oedema, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Fluconazole
    Indication: Antifungal Prophylaxis

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Metronidazole
    Indication: Antibiotic Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Levofloxacin
    Indication: Antibiotic Prophylaxis

Clofarabine
    Indication: Chemotherapy

Cytarabine
    Indication: Chemotherapy

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Acyclovir
    Indication: Antiviral Prophylaxis



Possible Fluconazole side effects in 63 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-12

Patient: 63 year old male

Reactions: Blood Bilirubin Increased, Hepatotoxicity, Nephropathy Toxic, Skin Toxicity, Escherichia Sepsis

Drug(s) suspected as cause:
Fluconazole
    Indication: Antifungal Prophylaxis

Clofarabine
    Indication: Chemotherapy

Levofloxacin
    Indication: Antibiotic Prophylaxis

Mycophenolate Mofetil
    Indication: Prophylaxis Against Graft Versus Host Disease

Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Anti-Thymocyte Globulin NOS
    Indication: Bone Marrow Conditioning Regimen

Cytarabine
    Indication: Chemotherapy

Acyclovir
    Indication: Antiviral Prophylaxis

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen

Metronidazole
    Indication: Antibiotic Prophylaxis



Possible Fluconazole side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-02-24

Patient: 33 year old female

Reactions: Abdominal Pain, Blood Bilirubin Increased, Metabolic Acidosis, Dyspnoea, Gastrointestinal Toxicity, Drug Interaction, Oesophageal Hypomotility, Multi-Organ Failure, Diarrhoea, Hepatotoxicity, Abdominal Distension, Septic Shock, Enterobacter Test Positive

Adverse event resulted in: death

Drug(s) suspected as cause:
Fluconazole

Other drugs received by patient possibly interacting with the suspect drug:
Tretinoin
    Dosage: unk ukn, unk
    Indication: Acute Promyelocytic Leukaemia

Voriconazole
    Dosage: unk ukn, unk

Other drugs received by patient: Dexamethasone



Possible Fluconazole side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-02-04

Patient: 33 year old female

Reactions: Multi-Organ Failure, Abdominal Pain, Hepatotoxicity, Diarrhoea, Abdominal Distension, Drug Interaction, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fluconazole

Other drugs received by patient possibly interacting with the suspect drug:
Posaconazole
    Indication: Acute Promyelocytic Leukaemia

Tretinoin
    Dosage: 45 mg/m2/day in two divided doses
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia

Other drugs received by patient: Dexamethasone; Idarubicin HCL



Possible Fluconazole side effects in 33 year old female

Reported by a physician from Spain on 2011-12-22

Patient: 33 year old female

Reactions: Multi-Organ Failure, Enterobacter Infection, Metabolic Acidosis, Hepatotoxicity, Gastrointestinal Toxicity, Septic Shock, Respiratory Distress

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vesanoid
    Administration route: Oral
    Indication: Acute Promyelocytic Leukaemia

Dexamethasone Tablets Usp, 1.5 MG
    Indication: Acute Promyelocytic Leukaemia

Posaconazole
    Indication: Antifungal Prophylaxis

Amphotericin B
    Indication: Gastrointestinal Toxicity

Fluconazole

Idarubicin HCL
    Indication: Acute Promyelocytic Leukaemia



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