Fludara (Fludarabine) - Death - Suspected Cause - Side Effect Reports

Possible Fludara side effects in 28 year old female

Reported by a physician from Japan on 2012-08-27

Patient: 28 year old female

Reactions: Encephalitis Herpes, Acute Graft Versus Host Disease, Encephalomyelitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Other drugs received by patient: Melphalan Hydrochloride; Prednisolone; Cyclosporine; Methotrexate; Prednisolone; Tacrolimus

Possible Fludara side effects in 45 year old female

Reported by a physician from United States on 2012-08-21

Patient: 45 year old female

Reactions: Epstein-Barr Virus Infection, Splenic Infection Fungal, Mycosis Fungoides Refractory, Granuloma, Pneumonia Cytomegaloviral

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-06-01

Cisplatin
    Dosage: unk
    Indication: Mycosis Fungoides

Cyclophosphamide
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Daunorubicin HCL
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Dexamethasone
    Dosage: unk
    Indication: Mycosis Fungoides

Etoposide
    Dosage: unk
    Indication: Mycosis Fungoides

Fludara
    Dosage: 2 cycles
    Indication: Mycosis Fungoides

Ifosfamide
    Dosage: unk
    Indication: Mycosis Fungoides

Prednisone
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Vincristine
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Possible Fludara side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Hypertension, Fusarium Infection

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Other drugs received by patient: Meropenem; Fentanyl Citrate; Cytarabine; Thiotepa; Melphalan Hydrochloride; Dilaudid; Busulfan

Possible Fludara side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 25.0 kg (55.0 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: 70 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: 229.9 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: 254 mg, qd
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Busulfan; Thiotepa; Dilaudid; Meropenem; Cytarabine; Melphalan Hydrochloride; Fentanyl Citrate

Possible Fludara side effects in 28 year old female

Reported by a physician from Japan on 2012-08-17

Patient: 28 year old female

Reactions: Encephalitis Herpes, Acute Graft Versus Host Disease, Encephalomyelitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Other drugs received by patient: Cyclosporine; Methotrexate; Tacrolimus; Prednisolone; Prednisolone; Melphalan Hydrochloride

Possible Fludara side effects in female

Reported by a physician from Japan on 2012-08-17

Patient: female, weighing 13.0 kg (28.6 pounds)

Reactions: Vomiting, Pneumonia, Cytomegalovirus Test Positive, Escherichia Urinary Tract Infection, Pyrexia, Staphylococcal Sepsis, Epstein-Barr Virus Infection, Pulmonary Haemorrhage, Bacterial Infection, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fludara
    Dosage: 15 mg/m2, qd (4 days); injection
    Indication: Aplastic Anaemia
    Start date: 2011-04-15
    End date: 2011-04-18

Thymoglobulin
    Indication: Aplastic Anaemia

Thymoglobulin
    Dosage: 33 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-04-15
    End date: 2011-04-18

Other drugs received by patient: Fluconazole; Acyclovir; Sulfamethoprim; Cyclophosphamide; Platelets; Hydroxyzine Pamoate; Human RED Blood Cells; Cyclosporine; Methylprednisolone Sodium Succinate

Possible Fludara side effects in female

Reported by a physician from United States on 2012-08-16

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Cardiac Failure, Respiratory Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Melphalan Hydrochloride; Busulfan; Fentanyl; Thiotepa; Cytarabine; Dilaudid; Meropenem

Possible Fludara side effects in 12 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-14

Patient: 12 year old female

Reactions: Acute Graft Versus Host Disease

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Melphalan Hydrochloride
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Therapeutic Radiopharmaceuticals
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Thymoglobulin
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Other drugs received by patient: Cyclosporine

Possible Fludara side effects in 28 year old female

Reported by a physician from Japan on 2012-08-14

Patient: 28 year old female

Reactions: Encephalitis Herpes, Acute Graft Versus Host Disease

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Possible Fludara side effects in 57 year old male

Reported by a physician from Japan on 2012-08-14

Patient: 57 year old male

Reactions: Graft Versus Host Disease

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Melphalan Hydrochloride
    Dosage: unk

Other drugs received by patient: Methotrexate; Tacrolimus

Possible Fludara side effects in female

Reported by a physician from Japan on 2012-08-13

Patient: female, weighing 48.0 kg (105.6 pounds)

Reactions: Stomatitis, Supraventricular Tachycardia, Shock Haemorrhagic, Disseminated Intravascular Coagulation, Endotoxaemia, Febrile Neutropenia, Pyrexia, Hypokalaemia, Venoocclusive Disease, Hypoalbuminaemia, Oedema, Neutropenia, Engraft Failure, Antithrombin III Decreased, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Fludara
    Dosage: 20 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-09-13
    End date: 2011-09-17

Thymoglobulin
    Dosage: 60 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-09-18
    End date: 2011-09-19

Other drugs received by patient: Azasetron Hydrochloride; Antibiotics-Resistant Lactic Acid Bacteriae; Dexchlorpheniramine Maleate; Rebamipide; Aprepitant; Itraconazole; Lansoprazole; Allopurinol; Acyclovir; Methylprednisolone Sodium Succinate; Polymyxin B Sulfate; Sulfamethoprim; Acetaminophen; Clostridium Butyricum; Acetaminophen; Lansoprazole; Cyclosporine; Dalteparin Sodium; Itraconazole; Melphalan Hydrochloride; Methotrexate

Possible Fludara side effects in 11 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 11 year old male

Reactions: Pneumonia Viral, Adenovirus Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Melphalan Hydrochloride
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Possible Fludara side effects in female

Reported by a physician from Japan on 2012-08-13

Patient: female, weighing 45.0 kg (99.0 pounds)

Reactions: Cytomegalovirus Test Positive, Haematuria, Thrombotic Microangiopathy, Post Transplant Lymphoproliferative Disorder, Viral Haemorrhagic Cystitis, Interstitial Lung Disease, Acute Graft Versus Host Disease in Skin, Sepsis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Fludara
    Dosage: 30 mg/m2, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-06-03
    End date: 2012-06-08

Thymoglobulin
    Dosage: 50 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2010-06-09
    End date: 2010-06-10

Other drugs received by patient: Phenobarbital TAB; Clobazam; Teicoplanin; Cytarabine; Lansoprazole; Tacrolimus; Acyclovir; Imipenem; Furosemide; Voriconazole; Roxithromycin; Mycophenolate Mofetil; Foscarnet Sodium; Thrombomodulin Alfa; Acyclovir; Miconazole Nitrate; Cefepime Hydrochloride; Lenograstim; Methylprednisolone; Famotidine; Risperidone; Diazepam; Meropenem; Omeprazole; Prednisone TAB; Filgrastim; Ursodiol; Fluconazole; Valacyclovir Hydrochloride; Micafungin Sodium; Antithrombin III Human; Grenol; Amphotericin B; Zosyn; Melphalan Hydrochloride; Heparin; Tacrolimus; Dopamine HCL

Possible Fludara side effects in female

Reported by a physician from United States on 2012-08-13

Patient: female, weighing 25.2 kg (55.4 pounds)

Reactions: Ischaemia, Pulmonary Alveolar Haemorrhage, Pericardial Effusion, Renal Failure, Respiratory Failure, Cardiac Failure, Sepsis, Pleural Effusion, Fusarium Infection, Hypertension

Adverse event resulted in: death, life threatening event, disablity

Drug(s) suspected as cause:
Clolar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-10
    End date: 2012-01-11

Fludara
    Dosage: 140 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-15

Mozobil
    Dosage: 6 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-16
    End date: 2012-06-18

Thymoglobulin
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-15
    End date: 2012-01-18

Thymoglobulin
    Dosage: unk
    Start date: 2012-06-16
    End date: 2012-06-19

Other drugs received by patient: Meropenem; Melphalan Hydrochloride; Cytarabine; Busulfan; Dilaudid; Fentanyl; Thiotepa

Possible Fludara side effects in 48 year old female

Reported by a physician from Japan on 2012-08-02

Patient: 48 year old female

Reactions: Hepatitis Fulminant, Engraftment Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Other drugs received by patient: Melphalan Hydrochloride; Rituximab; Total Body Irradiation

Possible Fludara side effects in female

Reported by a physician from Japan on 2012-07-31

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Lymphadenopathy, Pruritus, Disseminated Intravascular Coagulation, Pyrexia, Erythema, Abdominal Discomfort, Graft Versus Host Disease in Skin, Unevaluable Event, Melaena, Epistaxis, Blister, Metabolic Acidosis, Pneumonia, Mouth Haemorrhage, Urine Output Decreased, Pleurisy, General Physical Health Deterioration, Staphylococcal Sepsis, Post Transplant Lymphoproliferative Disorder, Septic Shock, Eye Discharge, Shock Haemorrhagic, Oral Herpes, Electrolyte Depletion, Conjunctival Hyperaemia, Pleural Effusion, Blood Glucose Increased, Renal Failure Acute, Stevens-Johnson Syndrome, White Blood Cell Count Decreased, Vomiting, Excoriation, Ascites, Vulvar Erosion, Diarrhoea, Skin Erosion, Blood Pressure Decreased, Eyelid Erosion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Allopurinol
    Dosage: unk
    Indication: Prophylaxis
    Start date: 2011-06-23
    End date: 2011-06-29

Corticosteroid NOS
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Fludara
    Dosage: 40 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-02-13
    End date: 2011-02-16

Thymoglobulin
    Dosage: 115 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-02-11
    End date: 2011-02-12

Other drugs received by patient: Cyclophosphamide; Fludarabine Phosphate; Prednisolone; Potassium Chloride; Magnesium Sulfate; Moxifloxacin Hydrochloride; Sulfamethoprim; Magnesium Oxide; Tacrolimus; Acyclovir; Mycophenolate Mofetil; Carbazochrome Sodium Sulfonate; Hydroxyzine Pamoate; Fentanyl Citrate; Rocuronium Bromide; RED Blood Cells, Concentrated; Micafungin Sodium; Granisetron Hydrochloride; Ursodiol; Sodium Bicarbonate; Rebamipide; Aciphex; Hydrocortisone Sodium Succinate; Omeprazole; Midazolam; Levofloxacin; Methylprednisolone Sodium Succinate; Dexchlorpheniramine Maleate; Ramosetron Hydrochloride; Platelets; Acetaminophen; Hydrocortisone Sodium Succinate; Lansoprazole; Valacyclovir Hydrochloride; Propofol; Mesna; Furosemide; Hydroxyzine Pamoate; Dexmedetomidine Hydrochloride

Possible Fludara side effects in 48 year old female

Reported by a physician from Japan on 2012-07-30

Patient: 48 year old female

Reactions: Engraftment Syndrome, Hepatitis Fulminant

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Other drugs received by patient: Rituximab; Melphalan Hydrochloride; Total Body Irradiation

Possible Fludara side effects in male

Reported by a physician from Japan on 2012-07-27

Patient: male, weighing 6.0 kg (13.2 pounds)

Reactions: Candida Pneumonia

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: 25 mg/m2, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-11-16
    End date: 2011-11-18

Thymoglobulin
    Dosage: 14 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-11-11
    End date: 2011-11-14

Other drugs received by patient: Cefepime Hydrochloride; Cyclophosphamide; Methylprednisolone Sodium Succinate; Prednisolone; Cyclosporine; Dexamethasone; Voriconazole; Etoposide

Possible Fludara side effects in 48 year old female

Reported by a physician from Japan on 2012-07-23

Patient: 48 year old female

Reactions: Engraftment Syndrome, Hepatitis Fulminant

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara

Other drugs received by patient: Total Body Irradiation; Melphalan Hydrochloride; Rituximab

Possible Fludara side effects in male

Reported by a consumer/non-health professional from Australia on 2012-07-20

Patient: male, weighing 88.0 kg (193.6 pounds)

Reactions: Fluid Overload, Weight Decreased, Abdominal Hernia, Dyspnoea, Femur Fracture, Bone Lesion, Squamous Cell Carcinoma, Mass, Soft Tissue Mass, Lung Neoplasm, Pain, Chronic Obstructive Pulmonary Disease, Osteoarthritis, Arthralgia, Lung Squamous Cell Carcinoma Metastatic, Decreased Appetite, Oxygen Saturation Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 300 mg, qd
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-04-13

Fludara
    Dosage: 40 mg, qd
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-04-13

Other drugs received by patient: Humalog; Hydrochlorothiazide; Metformin Hydrochloride; Albuterol Sulate; Furosemide; Ipratropium Bromide; Coloxyl; Moviprep; Magmin; Atenolol; Acetaminophen; Atorvastatin; Aspirin; Ipratropium Bromide; Rituximab; Sodium Chloride; Perindopril Erbumine; Ceftriaxone; Albuterol Sulate; Gentamicin

Possible Fludara side effects in male

Reported by a consumer/non-health professional from Denmark on 2012-07-19

Patient: male

Reactions: Muscular Weakness, Coordination Abnormal, Progressive Multifocal Leukoencephalopathy, Tremor, Paraesthesia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk
    Indication: Haemolysis

Cyclophosphamide
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2007-02-20
    End date: 2007-05-29

Fludara
    Dosage: unk
    Indication: Chronic Lymphocytic Leukaemia

Mabthera
    Dosage: every 2 weeks, maintainance every 2 months
    Start date: 2010-07-14
    End date: 2011-07-19

Mabthera
    Dosage: 230 df, q2w
    Indication: Chronic Lymphocytic Leukaemia Refractory
    Start date: 2007-02-20
    End date: 2007-03-14

Mabthera
    Dosage: q4w
    Indication: Haemolysis
    Start date: 2009-06-28
    End date: 2009-11-17

Other drugs received by patient: Chlorambucil; Chlorambucil; Prednisolone

Possible Fludara side effects in

Reported by a physician from United Kingdom on 2012-07-10

Patient:

Reactions: Histiocytosis Haematophagic

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2009-09-15
    End date: 2010-06-28

Fludara
    Dosage: unk
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2009-09-15
    End date: 2010-06-28

Possible Fludara side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-10

Patient:

Reactions: Histiocytosis Haematophagic

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk, 8 cycle
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2009-01-03
    End date: 2009-10-09

Fludara
    Dosage: unk, 8 cycle
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2009-01-03
    End date: 2009-10-09

Other drugs received by patient: Rituximab

Possible Fludara side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-10

Patient:

Reactions: Histiocytosis Haematophagic

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk, 6 cycles
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-03-04
    End date: 2010-11-10

Fludara
    Dosage: unk, 6 cycles
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-03-04
    End date: 2010-11-10

Possible Fludara side effects in

Reported by a physician from Japan on 2012-07-09

Patient:

Reactions: White Blood Cell Count Decreased, Diarrhoea, Acute Myeloid Leukaemia, Acute Graft Versus Host Disease in Skin, Platelet Count Decreased, Chronic Graft Versus Host Disease, Acute Graft Versus Host Disease in Intestine

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fludara
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2010-03-13
    End date: 2010-03-16

Thymoglobulin
    Dosage: 150 mg, once
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2010-03-15
    End date: 2010-03-15

Other drugs received by patient: Acyclovir; Immune Globulin NOS; Arbekacin; Albumin (Human); Cefepime Hydrochloride; Soya OIL; Dextromethorphan Hydrobromide; Spironolactone; Voriconazole; Itraconazole; Parenteral; Amphotericin B; Filgrastim; Wild Cherry Bark; Parenteral; Acyclovir; Acyclovir; Voriconazole; Itraconazole; Magnesium Oxide; Menatetrenone; Micafungin Sodium; Arbekacin; Pentamidine Isethionate; Insulin; Polymyxin B Sulfate; Potassium Chloride; Etizolam; Levothyroxine Sodium; Methylprednisolone Sodium Succinate; Insulin Human; Prednisolone Sodium; Cefepime Hydrochloride; Pantethine; Antibiotics-Resistant Lactic Acid Bacteriae; Vancomycin; Levofloxacin; Levofloxacin; Potassium Chloride; Tacrolimus; Sennoside A; Furosemide; Codeine Phosphate; Ursodiol; Sennoside A; Heparin; Albumin (Human); Teicoplanin; Magnesium Sulfate; Carbocisteine; Carbocisteine; Potassium Chloride; Granisetron Hydrochloride; Prednisolone Sodium; Magnesium Sulfate; Lansoprazole; Mycophenolate Mofetil; Bisacodyl; Chlorpromazine HCL; Micafungin Sodium; Amphotericin B; Pentazocine Lactate; Glycerin; Pentamidine Isethionate; Pazufloxacin; Lactated Ringer's; Dexamethasone

Possible Fludara side effects in 49 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-09

Patient: 49 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: Multi-Organ Failure, Lymphoproliferative Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: 51 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-11-29
    End date: 2011-12-03

Tacrolimus
    Dosage: unk
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2011-12-09
    End date: 2012-02-16

Thymoglobulin
    Dosage: 170 mg, qd
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2011-12-03
    End date: 2011-12-05

Treosulfan
    Dosage: 23.8 g, unk
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-11-29
    End date: 2011-12-02

Possible Fludara side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-09

Patient: 59 year old female, weighing 59.0 kg (129.8 pounds)

Reactions: Multi-Organ Failure, Lymphoproliferative Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: 48 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-02-17
    End date: 2012-02-21

Mycophenolate Mofetil
    Dosage: unk
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2012-02-27
    End date: 2012-03-21

Tacrolimus
    Dosage: unk
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2012-02-22
    End date: 2012-03-26

Thymoglobulin
    Dosage: 148 mg, qd
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2012-02-20
    End date: 2012-02-22

Treosulfan
    Dosage: 22.4 g, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-02-17
    End date: 2012-02-19

Possible Fludara side effects in 22 year old female

Reported by a physician from Japan on 2012-07-09

Patient: 22 year old female, weighing 38.0 kg (83.6 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Lymphadenopathy

Adverse event resulted in: death

Drug(s) suspected as cause:
Fludara
    Dosage: unk
    Indication: Bone Marrow Conditioning Regimen

Thymoglobulin
    Dosage: 2.5 mg/kg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-05-23
    End date: 2011-05-24

Other drugs received by patient: Ganciclovir

Possible Fludara side effects in 5 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-09

Patient: 5 year old female, weighing 20.0 kg (44.0 pounds)

Reactions: Multi-Organ Failure, Lymphoproliferative Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 180 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-05-04
    End date: 2012-05-07

Cyclosporine
    Dosage: unk
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2012-05-05
    End date: 2012-06-21

Fludara
    Dosage: 25 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2012-05-04
    End date: 2012-05-07

Thymoglobulin
    Dosage: 54 mg/day, qd
    Indication: Prophylaxis Against Transplant Rejection
    Start date: 2012-05-04
    End date: 2012-05-08

Possible Fludara side effects in female

Reported by a physician from Japan on 2012-07-06

Patient: female, weighing 41.0 kg (90.2 pounds)

Reactions: Histiocytosis Haematophagic, Viral Infection, Graft Versus Host Disease, Staphylococcal Infection, Febrile Neutropenia, Engraftment Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fludara
    Dosage: 40 mg, qd
    Indication: Adult T-Cell Lymphoma / Leukaemia
    Start date: 2011-01-04
    End date: 2011-01-09

Methylprednisolone Sodium Succinate
    Dosage: unk
    Indication: Pyrexia

Thymoglobulin
    Dosage: 50 mg, qd
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-01-10
    End date: 2011-01-10

Other drugs received by patient: Methotrexate; Fluconazole; Cefepime Hydrochloride; Acyclovir; Methotrexate; Methotrexate; Methotrexate; Sulfamethoprim; Busulfan; Filgrastim; Ciprofloxacin; Tacrolimus