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Gentamicin (Gentamicin Ophthalmic) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (13)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Gentamicin (Gentamicin Ophthalmic) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Gentamicin side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-23

Patient: 70 year old male, weighing 77.0 kg (169.4 pounds)

Reactions: Drug Interaction, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Gentamicin
    Dosage: unk
    Indication: Endocarditis
    Start date: 2011-01-03
    End date: 2011-01-19

Ramipril
    Dosage: 2.5 mg, qd
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-02-01
    End date: 2011-01-19

Zinacef
    Dosage: 1.5-3 g daily
    Indication: Endocarditis
    Start date: 2011-01-13
    End date: 2011-01-19

Other drugs received by patient: Fraxiparin, 0.3 ML, Amp, GSK; Fenistil, 1 MG, Novartis; Midazolam, AMP; Sobelin, 600 MG, Amp, Pfizer; Protaphane, Amp, Novo Nordisk



Possible Gentamicin side effects in 15 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-07

Patient: 15 year old female

Reactions: Overdose, Drug Interaction, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Bactrim
    Dosage: 1 df, three times per week
    Indication: Prophylaxis
    Start date: 2012-04-01

Cancidas
    Dosage: unk
    Start date: 2012-05-28
    End date: 2012-05-30

Ciprofloxacin HCL
    Dosage: unk
    Start date: 2012-05-28
    End date: 2012-06-04

Clavulanate Potassium
    Dosage: 1 df, 3x/day
    Start date: 2012-05-28
    End date: 2012-06-04

Gentamicin
    Dosage: unk
    Start date: 2012-05-26
    End date: 2012-05-30

Other drugs received by patient possibly interacting with the suspect drug:
Neoral
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Start date: 2012-04-23
    End date: 2012-05-31

Vancomycin HCL
    Dosage: 1 g, 2x/day
    Start date: 2012-05-22
    End date: 2012-06-03

Vfend
    Dosage: 200 mg, 2x/day
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-14
    End date: 2012-05-25

Vfend
    Dosage: 200 mg, 2x/day
    Administration route: Oral
    End date: 2012-05-31

Other drugs received by patient: Colistin; Gentamicin; Neupogen



Possible Gentamicin side effects in 15 year old female

Reported by a individual with unspecified qualification from Ireland on 2012-08-06

Patient: 15 year old female

Reactions: Nephropathy Toxic, Drug Interaction, Multiple Drug Overdose, Respiratory Distress, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cancidas
    Dosage: ; iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-28
    End date: 2012-05-30

Cyclosporine
    Dosage: 200 mg; ;po
    Administration route: Oral
    Indication: Aplasia
    Start date: 2012-04-23
    End date: 2012-05-31

Gentamicin
    Dosage: 170 ug; ;iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-26
    End date: 2012-05-30

Ticarcillin Disodium / Clavulanate Potassium (Claventin / 00973701 / )
    Dosage: ; iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-28
    End date: 2012-06-01

Trimethoprim + Sulfamethoxazole
    Dosage: ; tid; iv
    Indication: Prophylaxis
    Start date: 2012-04-01

Vancomycin
    Dosage: 2 gm; iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-22

Voriconazole
    Dosage: ; iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-14
    End date: 2012-05-31

Other drugs received by patient: Colistin; Atgam; Ciprofloxacin; Filgrastim



Possible Gentamicin side effects in 15 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-26

Patient: 15 year old female

Reactions: Drug Interaction, Multiple Drug Overdose, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Cancidas
    Dosage: iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-28
    End date: 2012-05-30

Ciprofloxacin
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-28
    End date: 2012-06-04

Cyclosporine
    Dosage: 200 mg;po
    Administration route: Oral
    Indication: Aplasia
    Start date: 2012-04-23
    End date: 2012-05-31

Gentamicin
    Dosage: 170 ug;iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-26
    End date: 2012-05-30

Ticarcillin Disodium / Clavulanate Potassium (Claventin / 00973701 / )
    Dosage: iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-28
    End date: 2012-06-01

Trimethoprim + Sulfamethoxazole
    Dosage: tid;iv
    Indication: Prophylaxis
    Start date: 2012-04-01

Vancomycin
    Dosage: 2 gm;iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-22

Voriconazole
    Dosage: 400 mg;iv
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-05-14
    End date: 2012-05-31

Other drugs received by patient: Filgrastim; Colistin; Atgam



Possible Gentamicin side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-14

Patient: female

Reactions: Blood Pressure Increased, Body Temperature Increased, Drug Interaction, Weight Increased, Oedema Peripheral, Oliguria, Drug Administration Error, Renal Tubular Necrosis, Renal Failure Acute, Anuria

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Gentamicin
    Dosage: 320 mg, qd
    Administration route: Oral
    Start date: 2012-05-18
    End date: 2012-06-18

Ketoprofen
    Dosage: 1 df, bid
    Administration route: Oral
    Start date: 2012-06-18

Lasix
    Dosage: 1 df, qd
    Administration route: Oral

Losartan Potassium
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2012-06-18

Vancomycin HCL
    Dosage: 1 g, tid
    Indication: Device Related Infection
    Start date: 2012-05-18
    End date: 2012-06-18

Other drugs received by patient: Ceftriaxone; Spironolactone; Tramadol HCL; Sitagliptin



Possible Gentamicin side effects in 92 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-21

Patient: 92 year old female

Reactions: Overdose, International Normalised Ratio Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amikacin
    Start date: 2012-05-07
    End date: 2012-05-10

Gentamicin
    Start date: 2012-05-06
    End date: 2012-05-09

Minisintrom
    Administration route: Oral
    Start date: 2012-04-25

Piperacillin Sodium
    Start date: 2012-05-06
    End date: 2012-05-09

Primaxin
    Start date: 2012-05-07
    End date: 2012-05-21

Vancomycin HCL
    Start date: 2012-05-06
    End date: 2012-05-08

Other drugs received by patient: Acetaminophen; Nicardipine Hydrochloride; Pentoxifylline; Digoxin; Zolpidem Tartrate; Nebivolol HCL



Possible Gentamicin side effects in 73 year old female

Reported by a physician from Norway on 2012-02-23

Patient: 73 year old female

Reactions: Renal Failure, Dehydration, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Diovan
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-01

Gentamicin
    Dosage: parenteral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-01

Metformin HCL
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-01



Possible Gentamicin side effects in 88 year old female

Reported by a consumer/non-health professional from United States on 2012-02-03

Patient: 88 year old female

Reactions: Creatinine Renal Clearance Decreased, Renal Failure, Drug Interaction, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Digoxin
    Dosage: dose as used: unk

Gentamicin
    Dosage: dose as used: unk

Vancomycin
    Dosage: dose as used: unk

Other drugs received by patient possibly interacting with the suspect drug:
Furosemide
    Dosage: dose as used: unk

Polymycin B Sulfate
    Dosage: dose:1 million units
    Indication: Urinary Tract Infection



Possible Gentamicin side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-03

Patient: 74 year old male

Reactions: Renal Failure, Creatinine Renal Clearance Decreased, Drug Interaction, Blood Creatinine Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aspirin
    Dosage: dose as used: unk

Captopril
    Dosage: dose as used: unk

Gentamicin
    Dosage: dose as used: unk

Hydrochlorothiazide
    Dosage: dose as used: unk

Other drugs received by patient possibly interacting with the suspect drug:
Furosemide
    Dosage: dose as used: unk

Polymycin B Sulfate
    Dosage: dose:1 million units



Possible Gentamicin side effects in 69 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-02

Patient: 69 year old male, weighing 133.0 kg (292.6 pounds)

Reactions: Rhabdomyolysis, Drug Hypersensitivity, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cefepime
    Indication: Evidence Based Treatment

Gentamicin
    Indication: Infection

Vancomycin
    Indication: Evidence Based Treatment

Vancomycin

Vancomycin

Vancomycin
    Indication: Infection

Other drugs received by patient possibly interacting with the suspect drug:
Daptomycin
    Dosage: 8 mg/kg with weight of 133 kg
    Indication: Infection

Simvastatin

Other drugs received by patient: Levofloxacin



Possible Gentamicin side effects in 69 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-02

Patient: 69 year old male, weighing 133.0 kg (292.6 pounds)

Reactions: Rhabdomyolysis, Drug Hypersensitivity, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cefepime
    Indication: Evidence Based Treatment

Gentamicin
    Indication: Infection

Vancomycin

Vancomycin

Vancomycin
    Indication: Evidence Based Treatment

Vancomycin
    Indication: Infection

Other drugs received by patient possibly interacting with the suspect drug:
Daptomycin
    Dosage: 8 mg/kg with weight of 133 kg
    Indication: Infection

Simvastatin

Other drugs received by patient: Levofloxacin



Possible Gentamicin side effects in 69 year old male

Reported by a physician from United States on 2012-01-30

Patient: 69 year old male, weighing 133.0 kg (292.6 pounds)

Reactions: Rhabdomyolysis, Drug Hypersensitivity, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cefepime
    Indication: Evidence Based Treatment

Gentamicin
    Indication: Infection

Vancomycin
    Indication: Evidence Based Treatment

Vancomycin
    Indication: Infection

Other drugs received by patient possibly interacting with the suspect drug:
Daptomycin
    Dosage: 8 mg/kg with weight of 133 kg
    Indication: Infection

Simvastatin

Other drugs received by patient: Levofloxacin



Possible Gentamicin side effects in 20 year old female

Reported by a health professional (non-physician/pharmacist) from Colombia on 2011-10-14

Patient: 20 year old female, weighing 46.0 kg (101.2 pounds)

Reactions: Pregnancy With Injectable Contraceptive, Drug Ineffective, Maternal Exposure During Pregnancy, Unintended Pregnancy, Drug Interaction

Drug(s) suspected as cause:
Depo-Provera
    Dosage: 150 mg, every 3 months
    Indication: Contraception
    Start date: 2010-06-04
    End date: 2011-06-15

Gentamicin
    Dosage: unk
    Start date: 2011-03-29

Sulfamethoxazole and Trimethoprim
    Dosage: unk
    Administration route: Oral
    Start date: 2011-03-29

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