Index of reports
> Cases with Fatigue (60)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Herceptin (Trastuzumab) where reactions include fatigue. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 60 Next >>
Possible Herceptin side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-20
Patient:
Reactions: Abdominal Pain, Vomiting, Hypersensitivity, Nausea, Skin Toxicity, Mucosal Inflammation, Fatigue, Diarrhoea, Hepatotoxicity, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lapatinib
Dosage: arm b
Administration route: Oral
Indication: Breast Cancer
Cyclophosphamide
Indication: Breast Cancer
Lapatinib
Dosage: arm c
Administration route: Oral
Herceptin
Dosage: loading dose
Indication: Breast Cancer
Herceptin
Dosage: maintenance dose
Fluorouracil
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
Epirubicin
Indication: Breast Cancer
Possible Herceptin side effects in male
Reported by a physician from Korea, Republic of on 2012-08-16
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Xeloda
Dosage: date of most recent dose prior to sae: 31/jan/2012
Administration route: Oral
Indication: Gastric Cancer
Start date: 2011-12-21
Herceptin
Dosage: date of most recent dose prior to sae: 18/jan/2012, 330 mg
Indication: Gastric Cancer
Start date: 2011-12-21
Pertuzumab
Dosage: date of most recent dose prior to sae: 18/jan/2012, 840 mg
Indication: Gastric Cancer
Start date: 2011-12-21
Cisplatin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Other drugs received by patient: Ramosetron; Artemisia Asiatica; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Tramadol HCL; Albumin; Pethidine HCL; Phytonadione; Tranexamic Acid; Potassium Chloride; Potassium Phosphate, Monobasic; Albumin; Fresh Frozen Plasma; Tetracosactrin; Aprepitant; Dexamethasone; Loperamide Oxide; Megestrol Acetate; Potassium Chloride; Potassium Chloride; Potassium Phosphate, Monobasic; Albumin; Dihydrocodeine Bitartrate INJ; Methylprednisolone Sodium Succinate; Ramosetron; Lactobacillus Acidophilus; Joulie's Solution; Potassium Phosphate, Monobasic; Esomeprazole; Esomeprazole; RED Blood Cells; Aprepitant; Chlorpheniramine Maleate; Ranitidine; Ultracet; Potassium Chloride; Esomeprazole; Pethidine HCL; Remifentanil; Famotidine; Potassium Phosphate, Monobasic; Lenograstim; Bisacodyl; Magnesium Sulfate; Sodium Bicarbonate; Potassium Phosphate, Monobasic; Esomeprazole; Tramadol HCL; Albumin; Morphine HCL; Chlorpheniramine Maleate; Pethidine HCL; Dexamethasone; Potassium Chloride; Potassium Chloride; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Fresh Frozen Plasma; Ketoprofen; Fentanyl Citrate
Possible Herceptin side effects in male
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-07
Patient: male, weighing 82.2 kg (180.8 pounds)
Reactions: White Blood Cell Count Decreased, Hepatic Mass, Blood Pressure Increased, Fatigue, Arthralgia, Eosinophil Count Increased, Lymphocyte Count Decreased
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Herceptin
Start date: 2011-07-22
Herceptin
Start date: 2011-02-09
Herceptin
Start date: 2011-06-01
Herceptin
Start date: 2011-06-22
Herceptin
Start date: 2011-08-10
Herceptin
Indication: Metastatic Gastric Cancer
Start date: 2011-01-19
Other drugs received by patient: Avalide; Pantoprazole; Senokot; Avalide; Docusate; Pantoprazole Sodium; Dilaudid; Solucort
Possible Herceptin side effects in female
Reported by a physician from United States on 2012-08-01
Patient: female, weighing 75.4 kg (165.8 pounds)
Reactions: Vomiting, Lung Disorder, Neuropathy Peripheral, Fatigue, Hepatic Neoplasm Malignant, Ejection Fraction Decreased, Asthenia
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Gemcitabine; Carboplatin; Taxotere; Navelbine
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United Kingdom on 2012-07-27
Patient: female
Reactions: Chest Discomfort, Dyspnoea, Varicella, Pallor, Tremor, Blood Glucose Decreased, Fatigue, Onychoclasis, Cold Sweat
Drug(s) suspected as cause:
Herceptin
Possible Herceptin side effects in female
Reported by a physician from Germany on 2012-07-19
Patient: female
Reactions: Weight Decreased, Pulmonary Embolism, Pyrexia, Hyperhidrosis, Cardiac Disorder, Intestinal Perforation, Dyspepsia, Proteinuria, Epistaxis, Gingival Bleeding, Anaemia, Cardiomyopathy, Neutropenia, Hypersensitivity, Bone Pain, Pain, Chills, Skin Reaction, Abdominal Pain Upper, Polyneuropathy, Myalgia, Fatigue, Oedema, Dizziness, Myocardial Infarction, Nail Toxicity, Thrombocytopenia, Decreased Appetite, Vomiting, Dyspnoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Cerebrovascular Accident, Dysgeusia, Mucosal Inflammation, Anxiety, Diarrhoea, Impaired Healing, Arthralgia, Hypertension, Asthenia, Leukopenia
Drug(s) suspected as cause:
Avastin
Indication: Breast Cancer
Herceptin
Indication: Breast Cancer
Xeloda
Indication: Breast Cancer
Possible Herceptin side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-19
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite
Drug(s) suspected as cause:
Gemcitabine Hydrochloride
Dosage: on days 1 and 8 every 21 days
Indication: Breast Cancer
Herceptin
Dosage: within 2 weeks after curative surgery until 52 weeks of therapy was completed
Paclitaxel
Dosage: over 1 h on days 1 and 8 every 21 days
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1
Indication: Breast Cancer
Herceptin
Dosage: over 30 min weekly
Possible Herceptin side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-18
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Decreased Appetite, Leukopenia
Drug(s) suspected as cause:
Paclitaxel
Indication: Breast Cancer
Paclitaxel
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Gemcitabine Hydrochloride
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
Indication: Breast Cancer
Herceptin
Dosage: after curative surgery until 52 weeks of therapy was completed.
Gemcitabine Hydrochloride
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Possible Herceptin side effects in female
Reported by a physician from United States on 2012-07-11
Patient: female, weighing 135.2 kg (297.4 pounds)
Reactions: Nausea, Hyperhidrosis, Loss of Consciousness, Burning Sensation, Fatigue, Syncope, Dehydration, Dizziness, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: 900 mg
Taxotere
Dosage: 188 mg
Herceptin
Dosage: 278 mg
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United States on 2012-07-06
Patient: female, weighing 56.8 kg (124.9 pounds)
Reactions: Fatigue, Arthropathy, Neck Pain, Dysphonia, Mitral Valve Incompetence, Loose Tooth, Vocal Cord Paralysis, Cough
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Percocet; Salagen; Femara; Zometa
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United States on 2012-06-26
Patient: female, weighing 56.8 kg (124.9 pounds)
Reactions: Vocal Cord Paralysis, Arthropathy, Fatigue, Neck Pain, Dysphonia, Mitral Valve Incompetence, Loose Tooth, Cough
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Zometa; Femara; Percocet; Salagen
Possible Herceptin side effects in
Reported by a individual with unspecified qualification from United States on 2012-06-19
Patient:
Reactions: Thrombosis, Headache, Device Related Infection, Peripheral Sensory Neuropathy, Pericardial Effusion, Malaise, Dyspepsia, Granulocytopenia, Hypoxia, Pneumonitis, Blood Alkaline Phosphatase Increased, Hypotension, Anaemia, Hyperglycaemia, Dehydration, Neutropenia, Pain, Bone Pain, Hypokalaemia, Neutropenic Infection, Postoperative Wound Infection, Fatigue, Chest Pain, Depression, Lethargy, Vomiting, Dyspnoea, Lymphopenia, Alanine Aminotransferase Increased, Muscular Weakness, Febrile Neutropenia, Hypophosphataemia, Syncope, Arthralgia, Diarrhoea, Ejection Fraction Decreased, Hypermagnesaemia, Respiratory Tract Infection, Leukopenia, Infection
Drug(s) suspected as cause:
Vinorelbine Tartrate
Dosage: on day 8 and 15 of the 21 days cycle
Indication: Breast Cancer Metastatic
Herceptin
Docetaxel
Indication: Breast Cancer Metastatic
Herceptin
Indication: Breast Cancer Metastatic
Possible Herceptin side effects in 60 year old female
Reported by a individual with unspecified qualification from United States on 2012-06-01
Patient: 60 year old female, weighing 79.7 kg (175.3 pounds)
Reactions: Fatigue, Diarrhoea, Dehydration, Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Tarceva
Administration route: Oral
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
Herceptin
Indication: Breast Cancer
Possible Herceptin side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-31
Patient: female, weighing 80.8 kg (177.8 pounds)
Reactions: White Blood Cell Count Decreased, Vomiting, Fatigue, Nausea, Alopecia, Dizziness, Depression, Constipation
Drug(s) suspected as cause:
Herceptin
Start date: 2012-04-19
Herceptin
Indication: Breast Cancer
Start date: 2012-03-08
Herceptin
Start date: 2012-03-29
Other drugs received by patient: Omeprazole; Carboplatin; Nystatin; Docetaxel; Dexamethasone; Prochlorperazine; Trazodone HCL; Ciprofloxacin HCL; Paxil
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from Netherlands on 2012-05-30
Patient: female
Reactions: Fatigue, Pain in Extremity, Musculoskeletal Pain, Ejection Fraction Decreased, Alopecia, Musculoskeletal Chest Pain, Fluid Retention
Drug(s) suspected as cause:
Herceptin
Possible Herceptin side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-05-30
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite
Drug(s) suspected as cause:
Paclitaxel
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Gemcitabine Hydrochloride
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
Indication: Breast Cancer
Herceptin
Dosage: after curative surgery until 52 weeks of therapy was completed.
Paclitaxel
Indication: Breast Cancer
Gemcitabine Hydrochloride
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-30
Patient: female
Reactions: Pain, Pyrexia, Somnolence, Cardiac Disorder, Fatigue, Unevaluable Event, Hepatic Pain, Rash, Alcohol Poisoning, Stress, Syncope, Neoplasm Malignant, Mastectomy, Mental Disorder, Neutropenia, Feeling Abnormal, Asthenia, Bite, Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Taxol; Oxycodone HCL
Possible Herceptin side effects in 65 year old female
Reported by a consumer/non-health professional from United States on 2012-05-28
Patient: 65 year old female, weighing 81.7 kg (179.8 pounds)
Reactions: Oropharyngeal Pain, Dysgeusia, Weight Increased, Fatigue, Diarrhoea, Swelling, DRY Mouth, Ejection Fraction Decreased
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Flagyl; Taxotere; Hydrochlorothiazide; Vancomycin
Possible Herceptin side effects in 65 year old female
Reported by a consumer/non-health professional from United States on 2012-05-28
Patient: 65 year old female, weighing 80.8 kg (177.8 pounds)
Reactions: White Blood Cell Count Decreased, Fatigue, Vomiting, Nausea, Alopecia, Dizziness, Depression, Constipation
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Prochlorperazine; Docetaxel; Carboplatin; Omeprazole; Paxil
Possible Herceptin side effects in 61 year old female
Reported by a physician from United States on 2012-05-25
Patient: 61 year old female
Reactions: Blood Bilirubin Increased, White Blood Cell Count Decreased, Stomatitis, Dyspnoea, Fatigue
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: over 1hr
Indication: Breast Cancer Metastatic
Start date: 2005-10-05
Tarceva
Dosage: started on cycle 1 day 3
Administration route: Oral
Indication: Breast Cancer Metastatic
Herceptin
Dosage: 30 min after paclitaxel infusion iv over 30 min
Indication: Breast Cancer Metastatic
Start date: 2005-10-05
Possible Herceptin side effects in 62 year old female
Reported by a physician from United States on 2012-05-17
Patient: 62 year old female, weighing 67.3 kg (148.1 pounds)
Reactions: Fatigue, Blindness Unilateral
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer Metastatic
Start date: 2011-11-03
End date: 2012-05-03
Avastin
Indication: Breast Cancer Metastatic
Start date: 2011-10-27
Carboplatin
Dosage: 4 auc
Indication: Breast Cancer Metastatic
Start date: 2011-11-03
Other drugs received by patient: Lisinopril
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United States on 2012-05-11
Patient: female
Reactions: Fatigue, Diarrhoea, Nausea, Rash
Drug(s) suspected as cause:
Tykerb
Dosage: 250mg per day
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2009-09-19
Herceptin
Xeloda
End date: 2011-11-01
Other drugs received by patient: Ondansetron; Ambien; Lisinopril; Toprol-XL; Effexor; Zometa
Possible Herceptin side effects in 84 year old female
Reported by a consumer/non-health professional from United States on 2012-05-11
Patient: 84 year old female
Reactions: Movement Disorder, Spinal Pain, Sciatica, Mouth Ulceration, Fatigue, Frequent Bowel Movements, Vulvovaginal Dryness, DRY Mouth, Sneezing, Milia, Back Pain, Musculoskeletal Pain, Acne, DRY Skin, Rash, Vulvovaginal Discomfort, Dysuria, Neuralgia
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer
Tykerb
Dosage: 1000mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-10-06
Other drugs received by patient: Actonel; Citracal + D; Multi-Vitamins; Lovaza; Vitamin B Complex CAP
Possible Herceptin side effects in 45 year old female
Reported by a consumer/non-health professional from United States on 2012-05-11
Patient: 45 year old female, weighing 68.1 kg (149.8 pounds)
Reactions: Myalgia, Burns Second Degree, Fatigue, Pain, Burns Third Degree
Drug(s) suspected as cause:
Herceptin
Other drugs received by patient: Carboplatin; Taxotere
Possible Herceptin side effects in male
Reported by a physician from Korea, Republic of on 2012-05-10
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Pneumonia Fungal, Fatigue, Aspergillus Test Positive, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Pertuzumab
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Amphotericin B
Indication: Product Used FOR Unknown Indication
Herceptin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Cisplatin
Dosage: date of most recent dose prior to sae: 18/jan/2012
Indication: Gastric Cancer
Start date: 2011-12-21
Xeloda
Dosage: date of most recent dose prior to sae: 31/jan/2012
Administration route: Oral
Indication: Gastric Cancer
Start date: 2011-12-21
Voriconazole
Indication: Product Used FOR Unknown Indication
Possible Herceptin side effects in
Reported by a physician from United States on 2012-05-02
Patient:
Reactions: Abdominal Pain, Stomatitis, Vomiting, Dyspnoea, Nausea, Bone Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Myalgia, Fatigue, Diarrhoea, Exfoliative Rash, Dehydration, Sensory Disturbance, Nervous System Disorder, Neutropenia, Leukopenia
Drug(s) suspected as cause:
Herceptin
Dosage: as loading dose in cycle 1 (1 cycle was of 3 weeks)
Indication: Breast Cancer Metastatic
Xeloda
Administration route: Oral
Indication: Breast Cancer Metastatic
Vinorelbine Tartrate
Indication: Breast Cancer Metastatic
Herceptin
Possible Herceptin side effects in 31 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-04-24
Patient: 31 year old female
Reactions: Central Nervous System Lesion, Anaemia, Headache, Herpes Zoster, Viith Nerve Paralysis, Fatigue, Neoplasm Malignant, Eyelid Ptosis, Spinal Disorder, Neutropenia, Lethargy
Drug(s) suspected as cause:
Doxorubicin HCL
Indication: Product Used FOR Unknown Indication
Herceptin
Herceptin
Herceptin
Indication: Product Used FOR Unknown Indication
Herceptin
Other drugs received by patient: Paclitaxel; Vinorelbine Tartrate; Thiotepa
Possible Herceptin side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-16
Patient: female, weighing 42.0 kg (92.3 pounds)
Reactions: Fatigue, Nausea, Blood Calcium Increased, Headache, Feeling Abnormal
Drug(s) suspected as cause:
Herceptin
Possible Herceptin side effects in female
Reported by a consumer/non-health professional from United States on 2012-04-04
Patient: female, weighing 43.1 kg (94.9 pounds)
Reactions: Fatigue, Nausea, Blood Calcium Increased, Headache, Feeling Abnormal
Drug(s) suspected as cause:
Herceptin
Possible Herceptin side effects in
Reported by a physician from United States on 2012-04-03
Patient:
Reactions: Fatigue, Anaemia, Tumour Pain, Hypotension, Urinary Tract Infection, Blood Creatinine Increased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Herceptin
Dosage: over 30 min on day 1, 8, 15, and 22 starting on week 2
Carboplatin
Dosage: auc 2 iv over 1 hour on days 1, 8, and 15
Indication: Breast Cancer Metastatic
Start date: 2005-05-18
Ixabepilone
Indication: Breast Cancer Metastatic
Start date: 2005-05-18
Herceptin
Dosage: over 90 min on day 1 (maintenance dose)
Herceptin
Dosage: over 90 min on day 1, week 1 only
Indication: Breast Cancer Metastatic
Start date: 2005-05-18
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