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Kadian (Morphine) - Toxicity To Various Agents - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Toxicity To Various Agents (43)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Kadian (Morphine) where reactions include toxicity to various agents. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 43   Next >>

Possible Kadian side effects in 57 year old female

Reported by a physician from United States on 2012-08-09

Patient: 57 year old female, weighing 68.9 kg (151.7 pounds)

Reactions: Unresponsive To Stimuli, Accidental Death, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Diazepam

Oxycodone HCL
    Dosage: po
    Administration route: Oral

Kadian
    Dosage: po
    Administration route: Oral



Possible Kadian side effects in 28 year old male

Reported by a physician from United States on 2012-08-09

Patient: 28 year old male, weighing 97.0 kg (213.4 pounds)

Reactions: Excoriation, Pulmonary Congestion, Unresponsive To Stimuli, Pulmonary Oedema, Intentional Drug Misuse, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Tramadol HCL

Ethanol

Chlordiazepoxide

Kadian

Diazepam



Possible Kadian side effects in 19 year old male

Reported by a physician from United States on 2012-08-09

Patient: 19 year old male

Reactions: Cardio-Respiratory Arrest, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Oxycodone HCL
    Dosage: po
    Administration route: Oral

Kadian
    Dosage: po
    Administration route: Oral

Alprazolam
    Dosage: po
    Administration route: Oral



Possible Kadian side effects in 29 year old male

Reported by a physician from United States on 2012-08-09

Patient: 29 year old male, weighing 106.0 kg (233.2 pounds)

Reactions: Pulmonary Congestion, Accidental Death, Pulmonary Oedema, Toxicity To Various Agents, Alcohol Poisoning, Cardiomegaly

Adverse event resulted in: death

Drug(s) suspected as cause:
Ethanol
    Indication: Intentional Drug Misuse

Heroin
    Indication: Intentional Drug Misuse

Kadian
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 33 year old male

Reported by a physician from United States on 2012-08-09

Patient: 33 year old male, weighing 105.2 kg (231.5 pounds)

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents, Drug Abuse

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian

Trazodone Hydrochloride

Citalopram Hydrobromide

Diphenhydramine Hydrochloride



Possible Kadian side effects in 50 year old male

Reported by a physician from United States on 2012-08-09

Patient: 50 year old male

Reactions: Unresponsive To Stimuli, Accidental Death, Intentional Drug Misuse, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Methamphetamine Hydrochloride
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Alprazolam
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Diazepam
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Oxycodone HCL
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 55 year old female

Reported by a physician from United States on 2012-08-09

Patient: 55 year old female

Reactions: Unresponsive To Stimuli, Completed Suicide, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Acetaminophen and Hydrocodone Bitartrate

Fluoxetine
    Dosage: po
    Administration route: Oral

Quetiapine

Kadian
    Dosage: po
    Administration route: Oral



Possible Kadian side effects in 27 year old female

Reported by a physician from United States on 2012-08-09

Patient: 27 year old female

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents, Intentional Drug Misuse

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: ; parn

Diphenhydramine Hydrochloride

Citalopram Hydrobromide



Possible Kadian side effects in 51 year old female

Reported by a physician from United States on 2012-08-09

Patient: 51 year old female

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents, Nephrosclerosis, Pallor, Hepatitis, Cardiomegaly, Completed Suicide, Ventricular Tachycardia, Brain Oedema, Carditis, Pulmonary Oedema, Pulse Absent, Pupil Fixed, Cold Sweat, Blood Pressure Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Promethazine HCL
    Indication: Completed Suicide

Kadian
    Indication: Completed Suicide

Fluoxetine
    Indication: Completed Suicide

Hydromorphone HCL
    Indication: Completed Suicide

Alprazolam
    Indication: Completed Suicide

Other drugs received by patient: Lisinopril; Rifampin; Dicloxacillin; Ciprofloxacin; Montelukast; Clindamycin



Possible Kadian side effects in 24 year old male

Reported by a physician from United States on 2012-08-09

Patient: 24 year old male, weighing 97.5 kg (214.6 pounds)

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Fluoxetine
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Acetaminophen and Hydrocodone Bitartrate
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Oxycodone HCL
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 27 year old male

Reported by a physician from United States on 2012-08-09

Patient: 27 year old male, weighing 103.0 kg (226.6 pounds)

Reactions: Pulmonary Alveolar Haemorrhage, Unresponsive To Stimuli, Accidental Death, Toxicity To Various Agents, Pulmonary Congestion, Hepatic Congestion, Brain Oedema, Pulmonary Oedema, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Citalopram Hydrobromide

Kadian

Methamphetamine Hydrochloride



Possible Kadian side effects in 30 year old male

Reported by a physician from United States on 2012-08-09

Patient: 30 year old male, weighing 81.6 kg (179.6 pounds)

Reactions: Completed Suicide, Toxicity To Various Agents, Asphyxia

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: , po
    Administration route: Oral

Ethanol
    Dosage: ; po
    Administration route: Oral

Dextromethorphan Hydrobromide
    Dosage: ; po
    Administration route: Oral



Possible Kadian side effects in 29 year old male

Reported by a physician from United States on 2012-08-09

Patient: 29 year old male

Reactions: Electrocardiogram ST Segment Abnormal, Vomiting, Unresponsive To Stimuli, Hypotension, Bundle Branch Block Right, Toxicity To Various Agents, Resuscitation, Loss of Consciousness, Pulmonary Congestion, Pulmonary Oedema, Pulse Absent, Opiates Positive, Apnoea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Pregabalin
    Dosage: iv
    Indication: Intentional Drug Misuse

Heroin
    Dosage: iv
    Indication: Intentional Drug Misuse

Clonazepam
    Dosage: iv
    Indication: Intentional Drug Misuse

Kadian
    Dosage: iv
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 55 year old male

Reported by a physician from United States on 2012-08-09

Patient: 55 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Ethanol
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Acetaminophen and Hydrocodone
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Skeletal Muscle Relaxant
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Phenobarbital TAB
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Amitriptyline Hydrochloride
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 36 year old male

Reported by a physician from United States on 2012-08-09

Patient: 36 year old male, weighing 76.7 kg (168.6 pounds)

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian

Ethanol

Diphenhydramine Hydrochloride

Alprazolam

Acetaminophen and Hydrocodone



Possible Kadian side effects in 50 year old male

Reported by a physician from United States on 2012-08-09

Patient: 50 year old male, weighing 114.8 kg (252.5 pounds)

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents, Drug Abuse

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian



Possible Kadian side effects in 38 year old female

Reported by a physician from United States on 2012-08-09

Patient: 38 year old female

Reactions: Completed Suicide, Toxicity To Various Agents, Alcohol Poisoning

Adverse event resulted in: death

Drug(s) suspected as cause:
Lisinopril
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Ethanol
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Codeine Sulfate
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Propoxyphene HCL
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Kadian
    Dosage: po
    Administration route: Oral
    Indication: Completed Suicide

Diazepam
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Methadone HCL
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Sertraline Hydrochloride
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Hydrocodone
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose



Possible Kadian side effects in 26 year old male

Reported by a physician from United States on 2012-08-09

Patient: 26 year old male, weighing 73.0 kg (160.6 pounds)

Reactions: Unresponsive To Stimuli, Toxicity To Various Agents, Intentional Drug Misuse, Drug Abuse

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: unk

Oxycodone HCL
    Dosage: unk

Ethanol
    Dosage: unk

Codeine Sulfate
    Dosage: unk

Heroin
    Dosage: unk



Possible Kadian side effects in 29 year old male

Reported by a physician from United States on 2012-08-09

Patient: 29 year old male

Reactions: Cardio-Respiratory Arrest, Unresponsive To Stimuli, Left Ventricular Hypertrophy, Blood PH Decreased, Pupil Fixed, Toxicity To Various Agents, Cardiomegaly

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: parn

Ethanol
    Dosage: parn



Possible Kadian side effects in 20 year old female

Reported by a physician from United States on 2012-08-09

Patient: 20 year old female

Reactions: Overdose, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Benzodiazepines
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Diazepam
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Venlafaxine Hydrochloride
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose

Marijuana
    Dosage: po
    Administration route: Oral
    Indication: Intentional Overdose



Possible Kadian side effects in 20 year old male

Reported by a physician from United States on 2012-08-09

Patient: 20 year old male

Reactions: Brain Death, Coma, Toxicity To Various Agents, Intentional Drug Misuse, Drug Abuse, Loss of Consciousness, Overdose, Respiratory Arrest, Brain Oedema

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Kadian
    Dosage: parn
    Indication: Intentional Drug Misuse

Heroin
    Dosage: parn
    Indication: Drug Abuse

Lorazepam
    Dosage: parn
    Indication: Drug Abuse

Oxycodone HCL
    Dosage: parn
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 34 year old male

Reported by a physician from United States on 2012-08-09

Patient: 34 year old male

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Amitriptyline Hydrochloride
    Administration route: Oral

Kadian
    Administration route: Oral

Other drugs received by patient: Buprenorphine



Possible Kadian side effects in 19 year old male

Reported by a physician from United States on 2012-08-09

Patient: 19 year old male

Reactions: Unresponsive To Stimuli, Blood Potassium Increased, Toxicity To Various Agents, Foaming AT Mouth, Pulse Absent, Pupil Fixed, Ventricular Fibrillation, Apnoea, Pulseless Electrical Activity

Adverse event resulted in: death

Drug(s) suspected as cause:
Heroin
    Indication: Intentional Drug Misuse

Kadian
    Indication: Intentional Drug Misuse

Codeine Sulfate
    Indication: Intentional Drug Misuse



Possible Kadian side effects in 51 year old male

Reported by a physician from United States on 2012-08-08

Patient: 51 year old male, weighing 84.8 kg (186.6 pounds)

Reactions: Contusion, Oedema Peripheral, Unresponsive To Stimuli, Accidental Death, Intentional Drug Misuse, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Indication: Intentional Drug Misuse

Lamotrigine

Ethanol



Possible Kadian side effects in 43 year old male

Reported by a physician from United States on 2012-08-08

Patient: 43 year old male

Reactions: Anoxia, Brain Death, Myocardial Ischaemia, Toxicity To Various Agents, Cardiomyopathy, Blood Glucose Decreased, Cardio-Respiratory Arrest, Balance Disorder, Completed Suicide, Brain Oedema, Pulmonary Oedema, Hepatosplenomegaly

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Kadian

Diltiazem Hydrochloride

Other drugs received by patient: Midazolam



Possible Kadian side effects in 38 year old female

Reported by a physician from United States on 2012-08-08

Patient: 38 year old female

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Oxycodone HCL

Diazepam

Kadian



Possible Kadian side effects in 55 year old male

Reported by a physician from United States on 2012-08-08

Patient: 55 year old male, weighing 68.0 kg (149.7 pounds)

Reactions: Excoriation, Wound, Unresponsive To Stimuli, Accidental Death, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Kadian
    Dosage: po
    Administration route: Oral
    Indication: Intentional Drug Misuse

Skeletal Muscle Relaxant
    Dosage: po
    Administration route: Oral

Acetaminophen and Hydrocodone
    Dosage: po
    Administration route: Oral

Carisoprodol

Meprobamate

Ethanol
    Dosage: po
    Administration route: Oral



Possible Kadian side effects in 37 year old female

Reported by a physician from United States on 2012-08-08

Patient: 37 year old female

Reactions: Brain Death, Hypothermia, Hypotension, Unresponsive To Stimuli, Atrial Fibrillation, Acidosis, Toxicity To Various Agents, Cerebral Hypoperfusion, Cardio-Respiratory Arrest, Hypoxic-Ischaemic Encephalopathy, Heart Rate Increased, Completed Suicide, NO Therapeutic Response

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclobenzaprine

Kadian

Ethanol



Possible Kadian side effects in 50 year old female

Reported by a physician from United States on 2012-08-08

Patient: 50 year old female

Reactions: Hepatic Necrosis, Blood Creatine Phosphokinase Increased, Unresponsive To Stimuli, Hypotension, Toxicity To Various Agents, Blood Lactic Acid Increased, Hepatic Steatosis, Ecchymosis, Completed Suicide, Ammonia Increased, Apnoea, Anuria

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ibuprofen
    Indication: Completed Suicide

Fluoxetine
    Indication: Completed Suicide

Kadian
    Indication: Completed Suicide

Feverall
    Indication: Completed Suicide

Alprazolam
    Indication: Completed Suicide

Oxycodone HCL
    Indication: Completed Suicide

Naproxen
    Indication: Completed Suicide

Eszopiclone
    Indication: Completed Suicide



Possible Kadian side effects in 45 year old female

Reported by a physician from United States on 2012-08-06

Patient: 45 year old female

Reactions: Emphysema, Contusion, Excoriation, Scab, Pleural Adhesion, Toxicity To Various Agents, Chronic Obstructive Pulmonary Disease, Cardio-Respiratory Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Amitriptyline Hydrochloride
    Dosage: po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Alprazolam
    Dosage: po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Cetirizine HCL
    Dosage: po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Kadian
    Dosage: po
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Paroxetine; Dexomethorphan; Nortriptyline



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