This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Keppra (Levetiracetam) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (1516)
Death (162)
Life Threatening Events (62)
Disability (28)
Reports by Reaction Type
Convulsion (219),
Foetal Exposure During Pregnancy (96),
Pregnancy (68),
Somnolence (66),
Maternal Exposure During Pregnancy (58),
Thrombocytopenia (57),
Status Epilepticus (47),
Dizziness (45),
Drug Ineffective (44),
Headache (41),
Pyrexia (41),
Grand MAL Convulsion (41)
Below are a few examples of reports where side effects / adverse reactions may be related to Keppra (Levetiracetam). For a complete list or a specific selection of reports, please use the links above.
Possible Keppra side effects in female
Reported by a physician from Argentina on 2012-08-27
Patient: female
Reactions: Partial Seizures, Premature Baby, Maternal Exposure During Pregnancy, Live Birth, Premature Labour
Drug(s) suspected as cause:
Clobazam
Dosage: 350mg per day
Administration route: Oral
Indication: Epilepsy
Keppra
Dosage: 1500mg per day
Administration route: Oral
Indication: Epilepsy
Start date: 2011-04-01
Lamictal
Dosage: 300mg per day
Administration route: Oral
Indication: Epilepsy
Possible Keppra side effects in male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-27
Patient: male
Reactions: Grand MAL Convulsion, Motor Dysfunction, Pancytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Dosage: strength: 500mg
Administration route: Oral
Indication: Epilepsy
Start date: 2009-01-01
End date: 2011-06-01
Keppra
Administration route: Oral
Start date: 2011-06-01
End date: 2012-06-02
Other drugs received by patient: Folic Acid; Acetaminophen; Ferrous Sulfate TAB; Ramipril; Zomig; Vastarel; Permixon; Nexium; Vasobral; Naftidrofuryl
Possible Keppra side effects in male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-27
Patient: male, weighing 73.0 kg (160.6 pounds)
Reactions: Intentional Overdose, Suicide Attempt
Drug(s) suspected as cause:
Citalopram Hydrobromide
Dosage: 100mg single dose
Administration route: Oral
Start date: 2012-08-23
Keppra
Dosage: 14000mg single dose
Administration route: Oral
Start date: 2012-08-23
Lamictal
Dosage: 2100mg single dose
Administration route: Oral
Start date: 2012-08-23
Lyrica
Dosage: 1500mg single dose
Administration route: Oral
Start date: 2012-08-23
Methionine CAP
Dosage: 150mg single dose
Administration route: Oral
Start date: 2012-08-23
Possible Keppra side effects in 83 year old male
Reported by a physician from Japan on 2012-08-27
Patient: 83 year old male
Reactions: Platelet Count Decreased, Rash
Drug(s) suspected as cause:
Keppra
Administration route: Oral
Indication: Simple Partial Seizures
Start date: 2012-03-04
End date: 2012-03-22
Keppra
Administration route: Oral
Indication: Partial Seizures With Secondary Generalisation
Start date: 2012-03-04
End date: 2012-03-22
Phenytoin Sodium CAP
Dosage: daily dose : 200 mg
Administration route: Oral
Indication: Partial Seizures With Secondary Generalisation
End date: 2012-03-22
Phenytoin Sodium CAP
Dosage: daily dose : 200 mg
Administration route: Oral
Indication: Simple Partial Seizures
End date: 2012-03-22
Plavix
Dosage: daily dose: 75 mg
Administration route: Oral
End date: 2012-03-22
Possible Keppra side effects in 87 year old female
Reported by a consumer/non-health professional from Germany on 2012-08-27
Patient: 87 year old female
Reactions: Blood Urine, Inflammation
Drug(s) suspected as cause:
Keppra
Start date: 2012-01-01
Keppra
Dosage: strenght: 250 mg
Start date: 2012-06-14
End date: 2012-01-01
Other drugs received by patient: Plavix; Lercanidipine; Metoprolol Tartrate
Possible Keppra side effects in 19 year old female
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: 19 year old female
Reactions: Drug Ineffective, Feeling Abnormal, Treatment Noncompliance, Convulsion
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in 63 year old female
Reported by a physician from France on 2012-08-27
Patient: 63 year old female
Reactions: Hyponatraemia
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Atorvastatin; Coumadin; Clobazam; Prednisone TAB; Levothyroxine Sodium
Possible Keppra side effects in female
Reported by a consumer/non-health professional from France on 2012-08-27
Patient: female
Reactions: Maternal Exposure During Pregnancy, Epilepsy
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Lamictal
Possible Keppra side effects in male
Reported by a physician from Germany on 2012-08-24
Patient: male, weighing 90.0 kg (198.0 pounds)
Reactions: Rash, Hyperhidrosis, Convulsion
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Carbamazepin Hexal
Possible Keppra side effects in 21 month old female
Reported by a physician from United States on 2012-08-24
Patient: 21 month old female
Reactions: Foetal Exposure During Pregnancy, Febrile Convulsion
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in 87 year old female
Reported by a consumer/non-health professional from Germany on 2012-08-24
Patient: 87 year old female
Reactions: Blood Urine
Drug(s) suspected as cause:
Keppra
Dosage: strenght: 250 mg
Start date: 2012-06-14
End date: 2012-01-01
Keppra
Start date: 2012-01-01
Other drugs received by patient: Plavix; Metoprolol Tartrate; Lercanidipine
Possible Keppra side effects in 38 year old female
Reported by a physician from United States on 2012-08-24
Patient: 38 year old female
Reactions: Homicidal Ideation, Depression, Suicidal Ideation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Lamictal
Possible Keppra side effects in 80 year old male
Reported by a consumer/non-health professional from France on 2012-08-24
Patient: 80 year old male
Reactions: Weight Decreased, Agitation, Drug Ineffective, Fall, Somnolence, Fatigue, Malaise, Mood Altered, Balance Disorder, Liver Function Test Abnormal, Anger, Dizziness, Depression, Decreased Appetite, Nervousness, Vomiting, Aggression, Irritability, Hostility, Vertigo, Memory Impairment, Asthenia, Attention Deficit / Hyperactivity Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Dosage: (1.5 tablets twice daily)
Administration route: Oral
Start date: 2012-01-01
Keppra
Administration route: Oral
Start date: 2012-06-01
End date: 2012-01-01
Other drugs received by patient: Enalapril Maleate; Neurontin; Celiprolol; Clobazam; Tamsulosin HCL; Plavix; Lercanidipine; Vitamin D
Possible Keppra side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: male
Reactions: Drug Ineffective
Drug(s) suspected as cause:
Dilantin
Dosage: 2 capsules of 100 mg in the morning and 3 capsules of 100 mg in the evening(2x/day)
Administration route: Oral
Indication: Convulsion
Start date: 2008-01-01
Keppra
Dosage: unk
Indication: Convulsion
Start date: 2007-01-01
End date: 2012-02-02
Possible Keppra side effects in 39 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-24
Patient: 39 year old male
Reactions: Cytolytic Hepatitis, Blood Creatinine Increased, Stevens-Johnson Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Indication: Epilepsy
Start date: 2012-05-15
End date: 2012-05-25
Malocide
Dosage: 50 mg tablet
Administration route: Oral
Indication: Cerebral Toxoplasmosis
Start date: 2012-05-15
End date: 2012-05-25
Sulfadiazine
Dosage: 500 mg
Administration route: Oral
Indication: Cerebral Toxoplasmosis
Start date: 2012-05-15
End date: 2012-05-25
Possible Keppra side effects in 65 year old female
Reported by a pharmacist from Switzerland on 2012-08-24
Patient: 65 year old female, weighing 55.3 kg (121.7 pounds)
Reactions: Vomiting, Pruritus, Chills, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Eosinophilia, Hepatic Enzyme Increased, C-Reactive Protein Increased, Oedema Peripheral, Rash Erythematous, Lymphocyte Morphology Abnormal
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Acetaminophen
Indication: Product Used FOR Unknown Indication
Start date: 2012-01-01
End date: 2012-05-25
Keppra
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Metronidazole
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-26
End date: 2012-05-25
Pantoprazole
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-01
End date: 2012-05-25
Rocephin
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-26
End date: 2012-05-21
Other drugs received by patient: Calcium Carbonate; Clindamycin HCL; Amoxicillin; Konakion; Meropenem; Prednisone TAB; Clemastine Fumarate
Possible Keppra side effects in male
Reported by a physician from Japan on 2012-08-24
Patient: male
Reactions: White Blood Cell Count Decreased, Anaemia, Thrombocytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Depakene
Possible Keppra side effects in 49 year old male
Reported by a consumer/non-health professional from United States on 2012-08-23
Patient: 49 year old male, weighing 80.7 kg (177.6 pounds)
Reactions: Agitation, Pain, Aggression, Off Label Use, Activities of Daily Living Impaired, Mood Altered, Insomnia, Anger, Bone Disorder, Gait Disturbance
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-23
Patient: female
Reactions: General Physical Health Deterioration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in 41 year old male
Reported by a physician from France on 2012-08-23
Patient: 41 year old male
Reactions: Optic Neuritis
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Coly-Mycin S Ophthalmic Drops
Indication: Cystic Fibrosis
Start date: 2007-09-25
Creon
Administration route: Oral
Indication: Pancreatic Insufficiency
Start date: 2007-09-25
Keppra
Administration route: Oral
Indication: Epilepsy
Start date: 2007-07-30
Lovenox
Indication: Product Used FOR Unknown Indication
Start date: 2007-09-25
Moviprep
Administration route: Oral
Indication: Constipation
Start date: 2007-09-25
Neoral
Administration route: Oral
Indication: Lung Transplant
End date: 2007-10-02
Nexium
Administration route: Oral
Indication: Prophylaxis Against Gastrointestinal Ulcer
Start date: 2007-09-25
Oxacillin
Administration route: Oral
Indication: Staphylococcal Infection
Start date: 2007-09-19
End date: 2007-11-07
Prednisolone
Administration route: Oral
Indication: Lung Transplant
Start date: 2007-09-24
Valganciclovir
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2007-09-24
End date: 2007-11-05
Other drugs received by patient: Paroxetine HCL; Atarax; Zolpidem
Possible Keppra side effects in 73 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-23
Patient: 73 year old female
Reactions: Quadriplegia, Catatonia, Pulmonary Embolism
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Transipeg; Effexor; Humalog; Lercanidipine; Crestor; Lexomil; Irbesartan and Hydrochlorothiazide; Acetaminophen; Glucophage
Possible Keppra side effects in male
Reported by a physician from United States on 2012-08-22
Patient: male
Reactions: Psychomotor Hyperactivity, Speech Disorder Developmental, Exposure During Breast Feeding, Restlessness, Foetal Exposure During Pregnancy, Abnormal Behaviour, Constipation, Aggression, Poor Quality Sleep, Choking, Coordination Abnormal
Drug(s) suspected as cause:
Keppra
Indication: Epilepsy
End date: 2009-02-03
Keppra XR
Start date: 2009-02-03
Keppra XR
Indication: Epilepsy
Start date: 2009-02-03
End date: 2009-07-16
Possible Keppra side effects in 65 year old male
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-22
Patient: 65 year old male, weighing 80.0 kg (176.0 pounds)
Reactions: Pruritus, Genital Infection Fungal
Drug(s) suspected as cause:
Keppra
Other drugs received by patient: Lisinopril; Amlodipine
Possible Keppra side effects in
Reported by a physician from Japan on 2012-08-22
Patient:
Reactions: Pneumonia Aspiration, Muscular Weakness, Somnolence
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in 19 year old female
Reported by a physician from Germany on 2012-08-22
Patient: 19 year old female
Reactions: Lipoatrophy
Drug(s) suspected as cause:
Cortisone Acetate
Dosage: depot
Indication: Seasonal Allergy
Keppra
Start date: 2010-07-08
Possible Keppra side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: male
Reactions: Drug Ineffective
Drug(s) suspected as cause:
Dilantin
Dosage: 2 capsules of 100 mg in the morning and 3 capsules of 100 mg in the evening(2x/day)
Administration route: Oral
Indication: Convulsion
Start date: 2008-01-01
Keppra
Dosage: unk
Indication: Convulsion
Start date: 2007-01-01
End date: 2012-02-02
Possible Keppra side effects in 80 year old male
Reported by a consumer/non-health professional from France on 2012-08-21
Patient: 80 year old male
Reactions: Weight Decreased, Agitation, Drug Ineffective, Somnolence, Malaise, Fatigue, Mood Altered, Balance Disorder, Liver Function Test Abnormal, Anger, Dizziness, Depression, Nervousness, Decreased Appetite, Vomiting, Aggression, Irritability, Hostility, Vertigo, Memory Impairment, Attention Deficit / Hyperactivity Disorder, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
Administration route: Oral
Start date: 2012-06-01
End date: 2012-01-01
Keppra
Dosage: (1.5 tablets twice daily)
Administration route: Oral
Start date: 2012-01-01
Other drugs received by patient: Enalapril Maleate; Tamsulosin HCL; Vitamin D; Plavix; Clobazam; Celiprolol; Lercanidipine; Neurontin
Possible Keppra side effects in
Reported by a physician from Germany on 2012-08-21
Patient:
Reactions: Death, Hypernatraemia
Adverse event resulted in: death
Drug(s) suspected as cause:
Keppra
Possible Keppra side effects in 47 year old male
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: 47 year old male, weighing 71.2 kg (156.6 pounds)
Reactions: Accident, Drug Level Increased, Pain, Injury, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin
Dosage: 100 mg, 4x/day
Administration route: Oral
Dilantin
Dosage: 100 mg, 3x/day
Administration route: Oral
Indication: Convulsion
Keppra
Dosage: 250 mg, 2x/day
Indication: Convulsion
Start date: 2012-01-01
Possible Keppra side effects in 62 year old female
Reported by a physician from Germany on 2012-08-21
Patient: 62 year old female, weighing 58.0 kg (127.6 pounds)
Reactions: Agitation, Suicidal Behaviour, Tachycardia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Keppra
|
