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Matulane (Procarbazine) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (7)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Matulane (Procarbazine) where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Matulane side effects in 63 year old male

Reported by a individual with unspecified qualification from United States on 2012-07-16

Patient: 63 year old male, weighing 102.1 kg (224.5 pounds)

Reactions: Night Sweats, Weight Decreased, Chills, Post Procedural Complication, Pyrexia, Fall, Haemothorax, Oedema Peripheral, Rotator Cuff Syndrome, Pleural Effusion, Thrombocytopenia, Acute Respiratory Failure, Decreased Appetite, Fluid Overload, Hypotension, Streptococcus Test Positive, Empyema, Haemorrhagic Anaemia, Renal Failure, Disease Recurrence, Sepsis, Asthenia, Leukopenia, Deep Vein Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Matulane

Other drugs received by patient: Osteo BI-Flex; Metformin Hydrochloride; Coumadin; Acetaminophen and Hydrocodone Bitartrate; Carvedilol; Lisinopril; Omeprazole



Possible Matulane side effects in 71 year old female

Reported by a physician from United States on 2012-07-11

Patient: 71 year old female

Reactions: Pneumonia, Sepsis Syndrome, Respiratory Failure, Hypoxia, Atrial Fibrillation, Pyrexia, Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Matulane



Possible Matulane side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-26

Patient: 74 year old male, weighing 81.2 kg (178.6 pounds)

Reactions: Excoriation, Anaemia, Hypotension, Neutropenic Sepsis, Tachycardia, Mental Status Changes, Atrial Fibrillation, Pyrexia, Fall, Cardiac Failure, Diarrhoea, Neutropenia, Cardiac Arrest, Lethargy, Cough

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Prednisone
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Lasix
    Indication: Cardiac Disorder
    End date: 2012-02-22

Matulane
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Spironolactone
    Indication: Cardiac Disorder
    End date: 2012-02-22

Coreg
    Indication: Cardiac Disorder
    End date: 2012-02-22

Cytoxan
    Start date: 2012-02-09
    End date: 2012-02-16

Lisinopril
    Indication: Cardiac Disorder
    End date: 2012-02-22

Vinblastine Sulfate
    Start date: 2012-02-09
    End date: 2012-02-16

Other drugs received by patient: Levofloxacin; Prevacid; Tamsulosin HCL; Klor-CON; Folic Acid; Multi-Vitamins; Bleomycin Sulfate; Dacarbazine; Lidocaine; Zofran; Doxorubicin HCL



Possible Matulane side effects in 29 year old male

Reported by a consumer/non-health professional from United States on 2012-03-14

Patient: 29 year old male, weighing 63.0 kg (138.7 pounds)

Reactions: Haemoglobin Decreased, Abdominal Pain, White Blood Cell Count Decreased, GAS Gangrene, Platelet Count Decreased, Neutropenia, Pyrexia, Clostridial Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Matulane
    Dosage: 200 mg;qd;po ; 150 mg;qd;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2012-02-16
    End date: 2012-01-01

Matulane
    Dosage: 200 mg;qd;po ; 150 mg;qd;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2012-02-16
    End date: 2012-01-01

Other drugs received by patient: Adriamycin PFS; Cytoxan; Etoposide; Bleomycin Sulfate; Prednisone; Vincristine



Possible Matulane side effects in 21 year old male

Reported by a consumer/non-health professional from France on 2012-01-13

Patient: 21 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Rash Morbilliform, Pyrexia, Transaminases Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Etopophos Preservative Free
    Dosage: from d1 to d3,course 1,course 2 on 12dec11,14dec11;d2
    Indication: Hodgkin's Disease
    Start date: 2011-11-22

Zofran
    Dosage: 1 df : 1 intake,14dec11;d2
    Administration route: Oral
    Start date: 2011-11-22

Bactrim DS
    Dosage: 1 df : 1 tab

Doxorubicin HCL
    Dosage: d1
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: on d8
    Indication: Hodgkin's Disease

Matulane
    Dosage: from d1 to d7,14dec11;d2,received until 06-dec-2011 instead of 28-nov-2011,
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-11-22
    End date: 2011-12-06

Vincristine
    Dosage: on d8
    Indication: Hodgkin's Disease

Prednisone TAB
    Dosage: from d1 to d10
    Indication: Premedication

Emend

Valacyclovir Hydrochloride

Cyclophosphamide
    Dosage: d1
    Indication: Hodgkin's Disease

Mesna
    Dosage: d1



Possible Matulane side effects in male

Reported by a physician from France on 2012-01-09

Patient: male, weighing 72.0 kg (158.4 pounds)

Reactions: Pyrexia, Rash Morbilliform

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zofran
    Dosage: 1unit cyclic
    Administration route: Oral
    Indication: Premedication
    Start date: 2011-11-22

Matulane
    Dosage: 200mg cyclic
    Administration route: Oral
    Indication: Hodgkin's Disease Stage IV
    Start date: 2011-11-22

Etoposide
    Dosage: 200mgm2 cyclic
    Indication: Hodgkin's Disease Stage IV
    Start date: 2011-11-22

Other drugs received by patient: Bactrim DS; Prednisone TAB; Cyclophosphamide; Doxorubicin HCL; Bleomycin Sulfate; Vincristine; Mesna; Valacyclovir Hydrochloride



Possible Matulane side effects in 19 year old female

Reported by a physician from Germany on 2011-12-23

Patient: 19 year old female

Reactions: Escherichia Test Positive, Iron Deficiency Anaemia, Chills, Presyncope, Urosepsis, Pyrexia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 25 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-29

Doxorubicin HCL
    Dosage: 25 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

Cyclophosphamide
    Dosage: 650 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

Matulane
    Dosage: 100 mg/m**2;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

Matulane
    Dosage: 100 mg/m**2;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-07-29

Rituximab (Rituximab)
    Dosage: 375 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

Rituximab (Rituximab)
    Dosage: 375 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-29

Prednisone TAB
    Dosage: 40 mg/m**2;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

Prednisone TAB
    Dosage: 40 mg/m**2;po
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-07-29

Bleomycin Sulfate
    Dosage: 10 mg/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-01-01
    End date: 2011-08-05

Etoposide
    Dosage: 100 mg/m**2;iv 100 ug/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-29

Etoposide
    Dosage: 100 mg/m**2;iv 100 ug/m**2;iv
    Indication: Hodgkin's Disease
    Start date: 2011-07-05

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