Index of reports
> Cases with Rash (16)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Mercaptopurine where reactions include rash. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Mercaptopurine side effects in 66 year old female
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: 66 year old female, weighing 83.0 kg (182.6 pounds)
Reactions: Diplopia, Diarrhoea, Rash
Drug(s) suspected as cause:
Mercaptopurine
Administration route: Oral
Indication: Crohn's Disease
Start date: 2010-08-01
End date: 2010-03-01
Metoprolol Succinate
Administration route: Oral
Indication: Blood Pressure Increased
Start date: 2006-01-01
End date: 2011-06-01
Mercaptopurine
Administration route: Oral
Start date: 2011-03-01
End date: 2011-06-01
Mercaptopurine
Administration route: Oral
Start date: 2011-06-01
Other drugs received by patient: Omeprazole; Simvastatin; Amitriptyline HCL; Lisinopril
Possible Mercaptopurine side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-25
Patient: female, weighing 14.9 kg (32.8 pounds)
Reactions: Anaemia, Hyponatraemia, Rash, Pyrexia, Ascites, Abdominal Pain Upper, Abdominal Compartment Syndrome, Respiratory Failure, Pneumonia Herpes Viral, Bone Marrow Failure, Neutropenia, Thrombocytopenia, Cardiac Arrest, Septic Shock, Infection in AN Immunocompromised Host
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Vincristine
Dosage: .99 mg
Methotrexate
Dosage: 24.5 mg
Dexamethasone
Dosage: 17.5 ml
Mercaptopurine
Dosage: 460 mg
Possible Mercaptopurine side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-25
Patient: female, weighing 14.9 kg (32.8 pounds)
Reactions: Coagulopathy, Hepatic Failure, Pyrexia, Abdominal Pain Upper, Laboratory Test Abnormal, Malaise, Bone Marrow Failure, Thrombocytopenia, Anaemia, Condition Aggravated, Hyponatraemia, Rash, Varicella, Abdominal Compartment Syndrome, Ascites, Respiratory Failure, Pneumonia Herpes Viral, Neutropenia, Immune System Disorder, Cardiac Arrest, Septic Shock
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Mercaptopurine
Dosage: 460 mg
Dexamethasone
Dosage: 17.5 mg
Vincristine Sulfate
Dosage: .99 mg
Methotrexate
Dosage: 24.5 mg
Possible Mercaptopurine side effects in 17 year old female
Reported by a consumer/non-health professional from Japan on 2012-04-24
Patient: 17 year old female
Reactions: Renal Impairment, Subileus, Rash, Leukoencephalopathy
Drug(s) suspected as cause:
Etoposide
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Indication: Acute Lymphocytic Leukaemia
Itraconazole
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: 2nd dose stopped on day 15
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 2nd dose stopped on 15 day
Indication: Acute Lymphocytic Leukaemia
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-17
Patient: 17 year old female
Reactions: Drug Level Increased, Inappropriate Antidiuretic Hormone Secretion, Drug Interaction, Rash, Subileus, Leukoencephalopathy
Drug(s) suspected as cause:
Tacrolimus
Dosage: unk
Indication: Lung Transplant
Vincristine
Dosage: 1.3 mg/day, 1 time
Indication: Chemotherapy
Asparaginase
Dosage: 3000 iu/mm/day on day 9, 11, 13, 16, 18, 20
Indication: Chemotherapy
Etoposide
Dosage: 100 mg/m2, 3 times
Indication: Chemotherapy
Mercaptopurine
Dosage: 25 mg/m2, 21 times
Indication: Chemotherapy
Dexamethasone
Methotrexate
Dosage: unk
Indication: Chemotherapy
Itraconazole
Dosage: unk
Indication: Prophylaxis
Leukovorin
Indication: Chemotherapy
Prednisolone
Dosage: 60 mg/mm/day on day 1-7
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Dosage: 40 mg/body 2 times
Indication: Chemotherapy
Cytarabine
Dosage: 2 g, unk 2 times
Indication: Chemotherapy
Methotrexate
Dosage: 500 mg/m2, unk
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-09
Patient: 17 year old female
Reactions: Renal Disorder, Drug Level Increased, Hyperglycaemia, Leukoencephalopathy, Subileus, Rash, Liver Disorder
Drug(s) suspected as cause:
Dexamethasone
Dosage: 40 mg/kg/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: 500 mg/m2/day
Asparaginase
Dosage: 3000 iu/m2/day
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Dosage: 25 mg/m2/day on days 1-21
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Other drugs received by patient possibly interacting with the suspect drug: Itraconazole
Indication: Prophylaxis
Tacrolimus
Indication: Immunosuppression
Other drugs received by patient: Cytarabine; Cytarabine; Vincristine; Vincristine; Prednisolone; Daunorubicin HCL
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-08
Patient: 17 year old female
Reactions: Renal Impairment, Rash, Leukoencephalopathy, Subileus
Drug(s) suspected as cause:
Methotrexate
Dosage: 2nd dose stopped on day 15
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Indication: Acute Lymphocytic Leukaemia
Etoposide
Indication: Acute Lymphocytic Leukaemia
Itraconazole
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 2nd dose stopped on 15 day
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Indication: Acute Lymphocytic Leukaemia
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-03
Patient: 17 year old female
Reactions: Subileus, Rash, Leukoencephalopathy
Drug(s) suspected as cause:
Methotrexate
Dosage: 500 mg/m2/day
Dexamethasone
Dosage: 40 mg/kg/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Vincristine
Dosage: 1.3 mg/m2/day
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: 2 g/m2/day
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Dosage: 25 mg/m2/day on days 1-21
Indication: Acute Lymphocytic Leukaemia
Other drugs received by patient: Cytarabine; Daunorubicin HCL; Prednisolone; Vincristine
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-03
Patient: 17 year old female
Reactions: Subileus, Rash, Leukoencephalopathy
Drug(s) suspected as cause:
Mercaptopurine
Dosage: 25 mg/m2/day on days 1-21
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 1.3 mg/m2/day
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Dosage: 40 mg/kg/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: 2 g/m2/day
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Methotrexate
Dosage: 500 mg/m2/day
Other drugs received by patient: Daunorubicin HCL; Prednisolone; Vincristine; Cytarabine
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-03
Patient: 17 year old female
Reactions: Hepatic Function Abnormal, Hyperglycaemia, Drug Interaction, Rash, Toxicity To Various Agents, Subileus, Renal Impairment, Inappropriate Antidiuretic Hormone Secretion, Leukoencephalopathy, Immunosuppressant Drug Level Increased
Drug(s) suspected as cause:
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: 500 mg/m2/day
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Dosage: 40 mg/kg/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: 2 g/m2/day
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Vincristine
Dosage: 1.3 mg/m2/day
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Dosage: 25 mg/m2/day on days 1-21
Indication: Acute Lymphocytic Leukaemia
Other drugs received by patient: Prednisolone; Daunorubicin HCL; Cytarabine; Vincristine
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-03
Patient: 17 year old female
Reactions: Subileus, Leukoencephalopathy, Rash
Drug(s) suspected as cause:
Mercaptopurine
Dosage: 25 mg/m2/day on days 1-21
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Leucovorin Calcium
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: 2 g/m2/day
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Vincristine
Dosage: 1.3 mg/m2/day
Indication: Acute Lymphocytic Leukaemia
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: 500 mg/m2/day
Dexamethasone
Dosage: 40 mg/kg/day on days 1-3
Indication: Acute Lymphocytic Leukaemia
Other drugs received by patient: Vincristine; Cytarabine; Daunorubicin HCL; Prednisolone
Possible Mercaptopurine side effects in 17 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-02
Patient: 17 year old female
Reactions: Dyskinesia, Leukoencephalopathy, Rash, Subileus
Drug(s) suspected as cause:
Cytarabine
Dosage: 2 g/m2/day on days 1-3
Dexamethasone
Dosage: 40 mg/body/day on days 1-3
Methotrexate
Etoposide
Dosage: 100 mg/m2/day on days 1-3
Vincristine
Dosage: 1.3 mg/m2/day
Leucovorin Calcium
Mercaptopurine
Dosage: 25 mg/m2/day on day 1-21
Other drugs received by patient: Tacrolimus; Prednisolone; Itraconazole
Possible Mercaptopurine side effects in 29 year old female
Reported by a physician from United States on 2012-02-27
Patient: 29 year old female
Reactions: Anal Fistula, Crohn's Disease, Rash, Intestinal Obstruction, Intestinal Stenosis
Drug(s) suspected as cause:
Humira
Indication: Crohn's Disease
Start date: 2010-03-01
Mercaptopurine
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Colazol; Adderall 5
Possible Mercaptopurine side effects in female
Reported by a consumer/non-health professional from United States on 2012-01-30
Patient: female, weighing 124.8 kg (274.7 pounds)
Reactions: Weight Decreased, Renal Disorder, Fistula, Nausea, Drug Ineffective, Rash, Weight Increased, Hospitalisation, Malaise, Diarrhoea, Blood Potassium Decreased, Hypophagia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Humira
Indication: Crohn's Disease
Start date: 2010-09-01
End date: 2011-02-01
Mercaptopurine
Indication: Crohn's Disease
Start date: 2011-03-01
End date: 2011-08-01
Humira
Start date: 2011-10-01
Other drugs received by patient: Methotrexate; Lantus; Ativan; Vicodin; Amaryl; Vitamin D; Folic Acid; Vitamin B-12
Possible Mercaptopurine side effects in 9 year old female
Reported by a physician from United States on 2012-01-30
Patient: 9 year old female, weighing 39.4 kg (86.7 pounds)
Reactions: Tachycardia, Pulmonary Embolism, Pyrexia, Constipation, Somnolence, Hypokalaemia, Partial Seizures, Sinusitis, Blepharospasm, Atrial Thrombosis, Hypotension, Cerebral Atrophy, Rash, Varicella Virus Test Positive, Tremor, Haemoglobin Decreased, Fungal Infection, Bacteraemia, Lacunar Infarction, Hypoalbuminaemia, Platelet Count Decreased, Neutropenia, Seizure Like Phenomena
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: 100 mg, 3x/day, subuctaneous; 100 mg once, subcutaneous
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-07
End date: 2011-06-10
Cytarabine
Dosage: 100 mg, 3x/day, subuctaneous; 100 mg once, subcutaneous
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-13
End date: 2011-06-16
Vincristine Sulfate
Dosage: 2 mg, weekly, intravenous; 1.9 mg, single, intravenous
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-04-08
End date: 2011-04-29
Vincristine Sulfate
Dosage: 2 mg, weekly, intravenous; 1.9 mg, single, intravenous
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-20
End date: 2011-06-20
*peg-Asparaginase (Asparaginase) Unknown
Dosage: 3150 iu, single, intramuscular
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-20
End date: 2011-06-20
Methotrexate
Dosage: see image
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-06
End date: 2011-06-06
Methotrexate
Dosage: see image
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-13
End date: 2011-06-13
Methotrexate
Dosage: see image
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-05-06
End date: 2011-05-06
Methotrexate
Dosage: see image
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-20
End date: 2011-06-20
Methotrexate
Dosage: see image
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-04-15
End date: 2011-04-15
Dalteparin Sodium
Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
Indication: Pulmonary Embolism
Start date: 2011-05-13
End date: 2011-06-26
Dalteparin Sodium
Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
Indication: Atrial Thrombosis
Start date: 2011-05-13
End date: 2011-06-26
Dalteparin Sodium
Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
Indication: Pulmonary Embolism
Start date: 2011-06-27
Dalteparin Sodium
Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
Indication: Atrial Thrombosis
Start date: 2011-06-27
Cyclophosphamide
Dosage: 1300 mg single, intravenous; 100mg once, subcutaneous
Start date: 2011-06-06
End date: 2011-06-06
Mercaptopurine
Dosage: 75 mg, once daily six days per week, oral; 100 mg, once per day on seventh day of week, oral
Administration route: Oral
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-06
End date: 2011-06-19
Mercaptopurine
Dosage: 75 mg, once daily six days per week, oral; 100 mg, once per day on seventh day of week, oral
Administration route: Oral
Indication: B Precursor Type Acute Leukaemia
Start date: 2011-06-06
End date: 2011-06-19
Other drugs received by patient: Zofran; Bactrim; Sodium Chloride 0.9%; Heparin; Ranitidine Hydrochloride; Emla; Acetaminophen
Possible Mercaptopurine side effects in 57 year old male
Reported by a consumer/non-health professional from United States on 2011-12-02
Patient: 57 year old male, weighing 68.0 kg (149.7 pounds)
Reactions: Abdominal Pain, Respiratory Disorder, Pruritus, Ocular Hyperaemia, Heart Rate Irregular, Rash, Headache, Abdominal Pain Upper
Drug(s) suspected as cause:
Mercaptopurine
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