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Methotrexate (Methotrexate) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (354)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 354   Next >>

Possible Methotrexate side effects in 13 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-08-27

Patient: 13 year old female

Reactions: Intra-Abdominal Haemorrhage, Pruritus, Febrile Neutropenia, Hyperaemia, Thoracic Haemorrhage, Mucosal Inflammation, Haemoglobin Decreased, Tumour Lysis Syndrome, Fungal Oesophagitis, Abdominal Distension, Pulmonary Oedema, Tachypnoea, Platelet Count Decreased, Renal Failure Acute, Blister

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Etoposide; Cytarabine; Leucovorin Calcium



Possible Methotrexate side effects in female

Reported by a physician from United Kingdom on 2012-08-22

Patient: female, weighing 67.5 kg (148.5 pounds)

Reactions: Small Intestinal Obstruction, Abdominal Adhesions

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra
    Dosage: wk 52 only
    Indication: Rheumatoid Arthritis

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2010-06-30

Placebo
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Alendronate Sodium; Symbicort; Prednisolone; Tiotropium; Lansoprazole; Prednisolone; Celecoxib; Albuterol Sulate; Theophylline; Simvastatin



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Hyperpyrexia, Anaphylactic Reaction, Chills, Pain, Hepatic Failure, Transaminases Increased, Splenic Infarction, Loss of Consciousness, Aortic Thrombosis, Off Label Use, Malaise, C-Reactive Protein Increased, Myositis, Dyspnoea, Hypotension, Arrhythmia, Lung Consolidation, Hypophosphataemia, Zygomycosis, Bacteraemia, Ventricular Tachycardia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cytarabine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Decadron Phosphate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Doxil
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

PEG-Asparaginase
    Dosage: day 2, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25
    End date: 2007-10-25

Velcade
    Dosage: day 1, 4, 8 and 11
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Methotrexate side effects in 72 year old male

Reported by a consumer/non-health professional from Canada on 2012-08-17

Patient: 72 year old male

Reactions: Colon Cancer, Septic Shock, Immobile

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2010-01-01
    End date: 2012-04-02

Prednisone TAB

Other drugs received by patient: Metformin HCL; Folic Acid; Verapamil; Glyburide; Vitamin B-12; Rivasa; Avalide; Coumadin; Lipitor



Possible Methotrexate side effects in male

Reported by a physician from Japan on 2012-08-17

Patient: male, weighing 65.0 kg (143.0 pounds)

Reactions: Pneumocystis Jiroveci Pneumonia, Arthralgia, Joint Swelling, Decreased Appetite

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Adalimumab
    Indication: Rheumatoid Arthritis
    Start date: 2010-07-13
    End date: 2011-01-12

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2009-07-01
    End date: 2011-01-21

Other drugs received by patient: Prednisolone; Amlodipine Besylate; Methotrexate; Diclofenac Sodium



Possible Methotrexate side effects in female

Reported by a physician from Netherlands on 2012-08-16

Patient: female, weighing 7.4 kg (16.3 pounds)

Reactions: Capillary Leak Syndrome, Hepatic Function Abnormal, Respiratory Failure, Disease Progression, Ascites

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Clofarabine
    Dosage: 11 mg (40 mg/m2), qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Cyclophosphamide
    Dosage: 80 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Cytarabine
    Dosage: 15 mg, od
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-28
    End date: 2010-07-28

Cytarabine
    Indication: Chemotherapy

Etoposide
    Dosage: 28 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-23
    End date: 2010-07-27

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 6 mgr, od
    Indication: Chemotherapy
    Start date: 2010-07-28
    End date: 2010-07-28

Prednisolone
    Indication: Chemotherapy

Prednisolone
    Dosage: 6 mgr, od
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-07-28
    End date: 2010-07-28

Other drugs received by patient: Itraconazole; Vancomycin; Dexamethasone; Filgrastim; Teicoplanin; Ciprofloxacin HCL; Ciprofloxacin HCL; Tramadol HCL; Vancomycin; Ceftazidime; Zofran; Vancomycin; Furosemide; Cotrim; Vancomycin; Vitamin K TAB; Cotrim; Itraconazole; Vancomycin; Vancomycin; Omeprazole; Acetaminophen; Ciprofloxacin; Furosemide; Ceftazidime; Furosemide; Omeprazole



Possible Methotrexate side effects in female

Reported by a physician from Germany on 2012-08-10

Patient: female

Reactions: Cellulitis, C-Reactive Protein Increased, Necrosis, Lymphangitis, Aplastic Anaemia, Skin Necrosis, Empyema, Thermal Burn, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2005-12-01
    End date: 2006-12-01

Hydrocortisone
    Indication: Rheumatoid Arthritis

Methotrexate
    Administration route: Oral
    Start date: 2007-06-19

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-12-01
    End date: 2006-12-01

Other drugs received by patient: Prednisolone; Etanercept



Possible Methotrexate side effects in 22 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: 22 year old male, weighing 93.1 kg (204.8 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Pain, Hyperglycaemia, Unresponsive To Stimuli, Pancytopenia, Disorientation, Pyrexia, Toxicity To Various Agents, Convulsion, Myalgia, Arthralgia, Chest Pain

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 65 year old male

Reported by a pharmacist from United States on 2012-08-09

Patient: 65 year old male

Reactions: Neoplasm Malignant, Pancytopenia, Toxicity To Various Agents, Acute Myocardial Infarction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in male

Reported by a physician from Japan on 2012-08-06

Patient: male, weighing 65.0 kg (143.0 pounds)

Reactions: Pneumocystis Jiroveci Pneumonia, Arthralgia, Joint Swelling, Decreased Appetite

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2010-07-13
    End date: 2011-01-12

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2009-07-01
    End date: 2011-01-21

Other drugs received by patient: Amlodipine Besylate; Prednisolone; Methotrexate; Diclofenac Sodium



Possible Methotrexate side effects in 74 year old male

Reported by a consumer/non-health professional from United States on 2012-08-03

Patient: 74 year old male

Reactions: Blood Bilirubin Increased, Pneumonia, Atrial Fibrillation, Hepatic Enzyme Increased, Death, Enterococcal Sepsis, Fluid Retention, Cardiac Failure Congestive

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Daunorubicin HCL
    Dosage: on days 1,8,15,22
    Indication: Acute Lymphocytic Leukaemia

Elspar

Methotrexate
    Dosage: day15
    Indication: Acute Lymphocytic Leukaemia

Prednisone
    Indication: Acute Lymphocytic Leukaemia

Sprycel
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-22

Vincristine
    Dosage: on days 1,8,15,22
    Indication: Acute Lymphocytic Leukaemia



Possible Methotrexate side effects in female

Reported by a physician from France on 2012-08-01

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Diverticulitis, Lymphopenia, Pulmonary Embolism, Cytomegalovirus Colitis, Peritonitis, Intestinal Perforation, Diffuse Large B-Cell Lymphoma, Lymphoma

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis

Etanercept
    Indication: Rheumatoid Arthritis

Mabthera
    Indication: Rheumatoid Arthritis

Methotrexate
    Indication: Rheumatoid Arthritis

Piroxicam
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Omeprazole; Ferrous Sulfate TAB; Vitamin D; Indapamide; Protelos; Aluminum Hydroxide and Magnesium Trisilicate; Calcium Carbonate; Prednisone TAB; Imodium; Folic Acid; Arixtra; Acetaminophen



Possible Methotrexate side effects in male

Reported by a consumer/non-health professional from Australia on 2012-08-01

Patient: male

Reactions: Pneumonia Legionella, Cardiac Arrest, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humira
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-15
    End date: 2011-07-15

Methotrexate
    Indication: Product Used FOR Unknown Indication
    End date: 2011-07-15

Other drugs received by patient: Cartia XT; Lipitor; Metoprolol Succinate



Possible Methotrexate side effects in male

Reported by a physician from Hungary on 2012-07-30

Patient: male, weighing 85.0 kg (187.0 pounds)

Reactions: Abdominal Strangulated Hernia, Peritonitis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis
    Start date: 2011-05-18

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01

Other drugs received by patient: Silymarin; Methylprednisolone; Allopurinol; Metoprolol Tartrate; Betahistine; Amlodipine Besilate / Lisinopril; Famotidine; Infliximab



Possible Methotrexate side effects in female

Reported by a physician from Netherlands on 2012-07-26

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Swelling, Ovarian Cancer

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-11-01
    End date: 2012-03-05

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1999-01-01

Other drugs received by patient: Synapause; Methotrexate; Calcium D3; Acenocoumarol; Folic Acid; Sotalol Hydrochloride



Possible Methotrexate side effects in female

Reported by a physician from Netherlands on 2012-07-23

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Swelling, Ovarian Cancer

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-11-01
    End date: 2012-03-05

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1999-01-01

Other drugs received by patient: F2 NOS; Acenocoumarol; Soltatol; Calcium D3; Synapause



Possible Methotrexate side effects in 53 year old female

Reported by a consumer/non-health professional from Ecuador on 2012-07-20

Patient: 53 year old female

Reactions: Abdominal Pain, Vomiting, Diarrhoea, Dehydration

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis

Rituximab
    Dosage: 2 cycles
    Start date: 2011-10-17
    End date: 2011-10-31

Rituximab
    Dosage: 2 cycles
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-01

Other drugs received by patient: Vitamin B Complex CAP; Naproxen; Prednisone; Gemfibrozil



Possible Methotrexate side effects in female

Reported by a physician from Switzerland on 2012-07-19

Patient: female, weighing 50.0 kg (110.0 pounds)

Reactions: Alveolitis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra
    Indication: Temporal Arteritis
    Start date: 2012-06-01
    End date: 2012-06-01

Methotrexate
    Administration route: Oral

Methotrexate
    Indication: Temporal Arteritis
    Start date: 2012-01-03
    End date: 2012-05-29

Methotrexate

Prednisone

Prednisone
    Administration route: Oral
    Indication: Temporal Arteritis
    Start date: 2011-09-01

Prednisone



Possible Methotrexate side effects in 75 year old female

Reported by a consumer/non-health professional from Japan on 2012-07-19

Patient: 75 year old female

Reactions: Duodenal Ulcer Perforation, RED Blood Cell Count Decreased, Interstitial Lung Disease, Post Procedural Complication, Post Procedural Infection, Peritonitis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Methotrexate
    Dosage: 10 mg, qw
    Indication: Rheumatoid Arthritis
    Start date: 2000-04-01
    End date: 2011-04-05

Methotrexate
    Dosage: 4 mg, qw
    Start date: 2011-07-15
    End date: 2011-08-08

Methotrexate
    Dosage: 4 mg, qw
    Start date: 2011-11-26
    End date: 2012-02-08

Methotrexate
    Dosage: 6 mg/ week
    Start date: 2012-02-08
    End date: 2012-05-09

Methotrexate
    Dosage: 6 mg, qw
    Start date: 2011-08-08
    End date: 2011-11-26

Orencia
    Dosage: 500 mg, unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-01-07

Orencia
    Dosage: 500 mg, unk
    Start date: 2011-02-03

Orencia
    Dosage: 500 mg, unk
    Start date: 2011-03-04

Orencia
    Dosage: 500 mg, unk
    Start date: 2011-05-14

Voltaren
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Fosamax; Prednisolone; Warfarin Potassium; Mucosta; Betamethasone; Sulfamethoxazole and Trimethoprim



Possible Methotrexate side effects in 61 year old male

Reported by a consumer/non-health professional from United States on 2012-07-14

Patient: 61 year old male

Reactions: Bladder Cancer

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Enbrel
    Indication: Arthritis

Enbrel
    Dosage: 50 mg, qw
    Indication: Psoriasis
    Start date: 2010-03-01
    End date: 2012-04-01

Methotrexate
    Dosage: 15 mg, qw
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-06-01
    End date: 2005-12-01

Methotrexate
    Indication: Arthritis

Sandimmune
    Indication: Arthritis

Sandimmune
    Dosage: 300 mg, per day
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2008-01-01
    End date: 2008-06-01



Possible Methotrexate side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 10 mg, q1week

Tracleer
    Dosage: unk
    Administration route: Oral
    Indication: Pulmonary Arterial Hypertension



Possible Methotrexate side effects in 50 year old female

Reported by a consumer/non-health professional from United States on 2012-07-13

Patient: 50 year old female, weighing 97.5 kg (214.6 pounds)

Reactions: Multi-Organ Failure, Haematochezia, Alopecia, Pollakiuria, Mucous Membrane Disorder, Full Blood Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 54 year old female

Reported by a physician from France on 2012-07-13

Patient: 54 year old female

Reactions: Leukaemia, Leukaemia Plasmacytic

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: cumulative total dose of doxorubicine of 504 mg (300 mg/m2)
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Etoposide
    Dosage: (500 mg)
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-01-01
    End date: 2011-01-01

Ifosfamide
    Dosage: 2480 mg
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-01-01
    End date: 2011-01-01

Mabthera
    Dosage: 650 mg
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Methotrexate
    Dosage: (4500 mg)
    Start date: 2012-05-14

Methotrexate
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-09-13
    End date: 2010-09-28

Methylprednisolone
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Prednisone
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Vincristine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16



Possible Methotrexate side effects in 51 year old male

Reported by a physician from United Kingdom on 2012-07-12

Patient: 51 year old male, weighing 110.0 kg (242.0 pounds)

Reactions: Liver Injury

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cimzia
    Indication: Rheumatoid Arthritis
    Start date: 2011-03-15
    End date: 2012-06-18

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1998-01-01
    End date: 2012-06-18

Other drugs received by patient: Acetaminophen and Codeine Phosphate



Possible Methotrexate side effects in 79 year old female

Reported by a pharmacist from United States on 2012-07-10

Patient: 79 year old female

Reactions: Subdural Haematoma, International Normalised Ratio Increased, Intracranial Pressure Increased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Methotrexate
    Dosage: 17.5mg once weekly po
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Warfarin Sodium
    Dosage: 2.5mg daily -5mg on m/th- daily except m/th po
    Administration route: Oral
    Indication: Atrial Fibrillation

Other drugs received by patient: Omeprazole -Prilosec 20mg DR CAP Take 1 CAP BY Mouth Daily. FOR Sympt



Possible Methotrexate side effects in 62 year old male

Reported by a physician from Japan on 2012-07-09

Patient: 62 year old male

Reactions: Spinal Compression Fracture, Interstitial Lung Disease, Staphylococcal Bacteraemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: restarted from 15sep

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2010-12-21

Prednisolone
    Dosage: also 15mg dose increased to 40mg/d on 14jan11 dose reduced to 30mg/d on 21jan11
    Indication: Rheumatoid Vasculitis

Other drugs received by patient: Bactrim; Imuran; Kenalog; Onealfa; Tacrolimus



Possible Methotrexate side effects in 55 year old female

Reported by a physician from United Kingdom on 2012-07-06

Patient: 55 year old female

Reactions: Pancytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Etoposide; Daunorubicin HCL; Cytarabine; Vincristine; Mercaptopurine



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-06

Patient: female

Reactions: Vomiting, Arachnoiditis, Respiratory Failure, Mental Status Changes, Headache, Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from Japan on 2012-07-06

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Pneumocystis Jiroveci Pneumonia, Diarrhoea, Interstitial Lung Disease, Pneumonia Pneumococcal

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Actemra
    Start date: 2009-11-20
    End date: 2011-02-07

Actemra
    Start date: 2011-06-01
    End date: 2011-06-01

Actemra
    Indication: Rheumatoid Arthritis
    Start date: 2009-07-21
    End date: 2009-07-21

Actemra
    Start date: 2011-04-15
    End date: 2011-04-15

Methotrexate
    Dosage: form: peroral agent
    Administration route: Oral
    Start date: 2008-03-14
    End date: 2008-05-15

Methotrexate
    Dosage: form: peroral agent
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2008-03-14

Methotrexate
    Dosage: form: peroral agent
    Administration route: Oral

Prednisolone
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Loxonin; Mucosta; Omeprazole; Risedronate Sodium



Possible Methotrexate side effects in 10 year old female

Reported by a physician from Korea, Democratic People's Republic of on 2012-07-06

Patient: 10 year old female

Reactions: Vomiting, Wernicke's Encephalopathy, Nausea, Malnutrition, Mental Status Changes, Convulsion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Cisplatin; Adriamycin PFS



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