DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Nexavar (Sorafenib) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Death (121)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include death. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 121   Next >>

Possible Nexavar side effects in male

Reported by a physician from United States on 2012-08-27

Patient: male

Reactions: Death, Adverse Drug Reaction, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 55 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23

Patient: 55 year old male

Reactions: Jaundice, Abdominal Pain, Hyperkalaemia, Chills, Mental Status Changes, Pyrexia, Loss of Consciousness, Death, Hepatic Encephalopathy, Fatigue, Cholangitis, Pleural Effusion, Thrombocytopenia, Renal Failure Acute, Nausea, Malnutrition, Urinary Tract Infection, Anaemia, Hyponatraemia, Rash, Bacteraemia, Dehydration, Ammonia Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-25
    End date: 2012-06-05

Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-06-01

Other drugs received by patient: Lorazepam; Diphenoxylate HCL and Atropine Sulfate; Lortab; Lasix; Albuterol; Aldactone; Protonix



Possible Nexavar side effects in 53 year old male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 53 year old male

Reactions: Confusional State, Agitation, Dysphagia, Pain, Anaemia, Failure To Thrive, Hypokalaemia, Death, Fatigue, Fluid Intake Reduced, Asthenia, Decreased Appetite, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg am, 200 mg pm x 21days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-07

Xeloda
    Dosage: 1500 mg am, 1650 mg pm x 14 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-01

Other drugs received by patient: Roxicodone; Compazine; Ferrous Fumarate; MS Contin; Phenergan HCL; Prinzide; Multi-Vitamin; Compazine



Possible Nexavar side effects in 56 year old male

Reported by a physician from United States on 2012-08-10

Patient: 56 year old male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 74 year old male

Reported by a physician from Japan on 2012-08-06

Patient: 74 year old male

Reactions: Death, Blood Creatine Phosphokinase Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-26

Nexavar
    Dosage: daily dose: 400 mg
    Administration route: Oral
    Start date: 2011-02-02
    End date: 2012-07-19



Possible Nexavar side effects in 59 year old male

Reported by a physician from United States on 2012-08-06

Patient: 59 year old male

Reactions: Death, Hepatic Neoplasm Malignant

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 76 year old male

Reported by a physician from Japan on 2012-08-02

Patient: 76 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Death, Cardio-Respiratory Arrest, Tumour Lysis Syndrome, Malaise, Palmar-Plantar Erythrodysaesthesia Syndrome, Blood Pressure Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-01-16
    End date: 2012-02-14

Nexavar
    Dosage: 200mg and 400mg alternately
    Administration route: Oral
    Start date: 2012-04-06
    End date: 2012-05-24

Other drugs received by patient: Miglitol; Tanatril; Pravastatin; Glyburide; Actos; Amlodipine



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from Indonesia on 2012-08-01

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 55 year old male

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient: 55 year old male

Reactions: Jaundice, Nausea, Pyrexia, Rash, Death, Fatigue, Dehydration, Ammonia Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 60 year old male

Reported by a consumer/non-health professional from United States on 2012-07-31

Patient: 60 year old male

Reactions: Death, Aphagia

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 57 year old male

Reported by a physician from United States on 2012-07-30

Patient: 57 year old male

Reactions: Death, Fatigue, Renal Disorder, Nausea, Hypersomnia

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 85 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-23

Patient: 85 year old male, weighing 45.0 kg (99.0 pounds)

Reactions: Death, Amylase Increased, Platelet Count Decreased, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Hirudoid; Losartan Potassium



Possible Nexavar side effects in 76 year old male

Reported by a physician from Japan on 2012-07-23

Patient: 76 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Death, Cardio-Respiratory Arrest, Tumour Lysis Syndrome, Malaise, Palmar-Plantar Erythrodysaesthesia Syndrome, Blood Pressure Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-01-16
    End date: 2012-02-14

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-02-01
    End date: 2012-02-20

Nexavar
    Dosage: 200mg and 400mg alternatively
    Administration route: Oral
    Start date: 2012-04-20

Other drugs received by patient: Amlodipine; Glyburide; Tanatril; Pravastatin; Actos; Miglitol



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from Korea, Republic of on 2012-07-23

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 72 year old female

Reported by a consumer/non-health professional from United States on 2012-07-20

Patient: 72 year old female

Reactions: Blood Bilirubin Increased, Vomiting, Platelet Transfusion, Nausea, Rash Pruritic, Death, Haematochezia, NO Adverse Event, Transfusion, Fluid Retention

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-02-14
    End date: 2012-02-17

Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-01-01

Nexavar
    Dosage: 200 mg, qd
    Start date: 2012-02-20

Nexavar
    Dosage: 1 am and 1 pm (dosage adjusted daily based on bilirubuin results)

Other drugs received by patient: Insulin; Blood and Related Products; Antihypertensives; Platelets



Possible Nexavar side effects in 54 year old female

Reported by a consumer/non-health professional from China on 2012-07-17

Patient: 54 year old female

Reactions: Death, Gastrointestinal Haemorrhage, Abdominal Pain Upper

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 60 year old male

Reported by a physician from United States on 2012-07-17

Patient: 60 year old male

Reactions: Aphagia, Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 85 year old male

Reported by a consumer/non-health professional from Indonesia on 2012-07-16

Patient: 85 year old male

Reactions: Pulmonary Haemorrhage, Death, Dyspnoea, Lung Infiltration

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 74 year old male

Reported by a physician from Japan on 2012-07-12

Patient: 74 year old male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 74 year old male

Reported by a physician from Japan on 2012-07-05

Patient: 74 year old male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 57 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-03

Patient: 57 year old male

Reactions: Death, Aphagia, Renal Failure, Hospitalisation, Dehydration

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 60 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-26

Patient: 60 year old male

Reactions: Death, Aphagia

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 59 year old male

Reported by a consumer/non-health professional from United States on 2012-06-26

Patient: 59 year old male, weighing 115.0 kg (253.0 pounds)

Reactions: Death, Cerebral Ischaemia, Convulsion

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Oxycontin; Hydralazine Hydrochloride; Hydralazine Hydrochloride; Omeprazole; Acyclovir; Percocet; Magnesium Oxide; Lidocaine; Polyethylene Glycol; Sulfamethoxazole and Trimethoprim; Aspirin; Norvasc; Lidocaine; Rapamune; Morphine; Acetaminophen; Percocet; Norvasc; Rapamune; Rapamune



Possible Nexavar side effects in 70 year old

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-26

Patient: 70 year old

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Indication: Oesophageal Carcinoma

Nexavar
    Indication: Spinal Cord Neoplasm

Other drugs received by patient: Forteo



Possible Nexavar side effects in 67 year old female

Reported by a pharmacist from United States on 2012-06-12

Patient: 67 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 85 year old male

Reported by a physician from Japan on 2012-06-12

Patient: 85 year old male

Reactions: Death, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 76 year old female

Reported by a consumer/non-health professional from Indonesia on 2012-06-11

Patient: 76 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-05-31

Patient: 61 year old male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from Korea, Republic of on 2012-05-31

Patient: male

Reactions: Death, Diplopia, Disease Progression

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 66 year old female

Reported by a pharmacist from United States on 2012-05-31

Patient: 66 year old female

Reactions: Death, Fatigue, Vomiting, Diarrhoea

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Vitamin D; Furosemide; Multi-Vitamin; Nadolol; Spironolactone; Prilosec; Vitamin B Complex CAP



 Page 1   Next >>

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017