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Nexavar (Sorafenib) - Decreased Appetite - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Decreased Appetite (188)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include decreased appetite. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 188   Next >>

Possible Nexavar side effects in 54 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient: 54 year old male

Reactions: Blood Pressure Increased, Weight Decreased, Nausea, Pain in Extremity, Hypotension, Rash, Skin Irritation, Frequent Bowel Movements, Fatigue, Diarrhoea, Gait Disturbance, Decreased Appetite

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-24

Patient: 73 year old female, weighing 48.0 kg (105.6 pounds)

Reactions: Hyperbilirubinaemia, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, General Physical Health Deterioration, Encephalopathy, Dizziness, Hypertension, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2010-01-08
    End date: 2010-01-10

Nexavar
    Dosage: 800 mg, qd
    Administration route: Oral
    Start date: 2010-01-13
    End date: 2010-01-19

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-01-20
    End date: 2010-03-02

Other drugs received by patient: Aldactone; Shakuyakukanzoutou; Omeprazole; Urso 250; Medicon; Allegra; Acetaminophen; Onealfa



Possible Nexavar side effects in 63 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-21

Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)

Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, tid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-07
    End date: 2011-01-28

Nexavar
    Dosage: 200 mg, tid
    Administration route: Oral
    Indication: Metastases To Lung
    Start date: 2011-03-05
    End date: 2011-03-24

Nexavar
    Dosage: 200 mg, tid
    Administration route: Oral
    Start date: 2011-03-17

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2011-04-22
    End date: 2011-08-22

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2011-10-25
    End date: 2011-10-30

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2011-08-31
    End date: 2011-10-23

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2011-11-03

Other drugs received by patient: Urepearl; Epirubicin Hydrochloride; Famotidine; Amlodipine; Miriplatin



Possible Nexavar side effects in 58 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20

Patient: 58 year old male

Reactions: Weight Decreased, Fatigue, Neck Pain, Musculoskeletal Stiffness, Blood Glucose Fluctuation, Gallbladder Disorder, Gastrooesophageal Reflux Disease, Muscle Spasms, Decreased Appetite, Back Pain, Vomiting, Nausea, DRY Skin, Anxiety, Insomnia, Asthenia

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 53 year old male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 53 year old male

Reactions: Confusional State, Agitation, Dysphagia, Pain, Anaemia, Failure To Thrive, Hypokalaemia, Death, Fatigue, Fluid Intake Reduced, Asthenia, Decreased Appetite, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg am, 200 mg pm x 21days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-07

Xeloda
    Dosage: 1500 mg am, 1650 mg pm x 14 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-01

Other drugs received by patient: Roxicodone; Compazine; Ferrous Fumarate; MS Contin; Phenergan HCL; Prinzide; Multi-Vitamin; Compazine



Possible Nexavar side effects in 63 year old male

Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-08-17

Patient: 63 year old male, weighing 67.0 kg (147.4 pounds)

Reactions: Weight Decreased, Blood Pressure Increased, Abdominal Pain, Back Pain, Urinary Tract Infection, Diplopia, Diarrhoea, Metastases To Bone, Eye Disorder, Decreased Appetite

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Preparations Increasing Uric Acid Excretion; Omeprazole; Captopril; Hydrochlorothiazide; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Hydrochlorothiazide



Possible Nexavar side effects in 60 year old male

Reported by a physician from United States on 2012-08-15

Patient: 60 year old male

Reactions: Weight Decreased, Cellulitis, Retching, Pain in Extremity, Pyrexia, Fall, Erythema, Diarrhoea, Oedema Peripheral, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Analgesics



Possible Nexavar side effects in 54 year old male

Reported by a physician from Japan on 2012-08-13

Patient: 54 year old male, weighing 40.5 kg (89.1 pounds)

Reactions: Blood Bilirubin Increased, Blood Alkaline Phosphatase Increased, Pneumonia, Hepatic Function Abnormal, Anaemia, Constipation, Ascites, Diarrhoea, Platelet Count Decreased, Metastases To Bone, Liver Carcinoma Ruptured, Bilirubin Conjugated Increased, Decreased Appetite

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-08-10
    End date: 2009-09-10

Nexavar
    Dosage: 600 mg, qd
    Administration route: Oral
    Start date: 2009-09-12
    End date: 2009-09-25

Other drugs received by patient: Fentanyl-100; TPN; Zolpidem; Bismuth Subnitrate; Voltaren; Lansoprazole; Albumin Tannate; Oxycodone Hydrochloride; Elemenmic



Possible Nexavar side effects in 64 year old male

Reported by a pharmacist from Japan on 2012-08-09

Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Diarrhoea, Hepatic Neoplasm Malignant, Hyperammonaemia, Eczema, Decreased Appetite, Ascites

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg/day
    Administration route: Oral
    Start date: 2009-09-09
    End date: 2009-10-01

Nexavar
    Dosage: 400 mg/day
    Administration route: Oral
    Start date: 2009-10-28
    End date: 2009-10-30

Nexavar
    Dosage: 600 mg/day
    Administration route: Oral
    Start date: 2009-10-02
    End date: 2009-10-27

Nexavar
    Dosage: 800 mg/day
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-08-06
    End date: 2009-09-08

Other drugs received by patient: Lamivudine; Mucosta; Aldactone; Lasix; Oxycontin; Rabeprazole Sodium; Loxoprofen; Fentanyl-100; Pastaron; Ensure [minerals Nos,vitamins Nos]; Hepsera; Hypoca; Morphine; Aldactone



Possible Nexavar side effects in 62 year old male

Reported by a physician from Japan on 2012-08-08

Patient: 62 year old male, weighing 57.0 kg (125.4 pounds)

Reactions: Fatigue, Dyspnoea, Diarrhoea, Bone Marrow Failure, Acute Respiratory Distress Syndrome, Decreased Appetite

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 800 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-03-10
    End date: 2012-03-20

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-04-01
    End date: 2012-05-01

Nexavar
    Dosage: 400 mg, qod
    Start date: 2012-04-28
    End date: 2012-04-30

Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-03-29
    End date: 2012-04-27

Other drugs received by patient: Silece; Risperidone; Zometa; Fentanyl Citrate; Lyrica; Loxonin; Lamivudine; Hepsera



Possible Nexavar side effects in 63 year old female

Reported by a physician from Japan on 2012-08-06

Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)

Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 200-400 mg
    Administration route: Oral
    Start date: 2011-08-01

Nexavar
    Dosage: daily dose 600 mg
    Administration route: Oral
    Indication: Metastases To Lung
    Start date: 2011-03-05
    End date: 2011-03-24

Nexavar
    Dosage: 200 mg, tid
    Administration route: Oral
    Start date: 2011-03-17

Nexavar
    Dosage: 200 mg, tid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-07
    End date: 2011-01-28

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2011-04-22

Other drugs received by patient: Amlodipine; Miriplatin; Epirubicin Hydrochloride; Famotidine; Urepearl



Possible Nexavar side effects in 85 year old male

Reported by a physician from Japan on 2012-07-31

Patient: 85 year old male

Reactions: Upper Limb Fracture, Diarrhoea, Fall, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-06-07
    End date: 2011-08-30



Possible Nexavar side effects in 59 year old male

Reported by a physician from United States on 2012-07-27

Patient: 59 year old male, weighing 126.8 kg (279.0 pounds)

Reactions: Myalgia, Blood Bilirubin Increased, Fatigue, Ammonia Increased, Encephalopathy, Decreased Appetite, Lethargy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Hydrochlorothiazide; Losartan Potassium and Hydrochlorothiazide; Protonix



Possible Nexavar side effects in 75 year old male

Reported by a physician from Japan on 2012-07-24

Patient: 75 year old male, weighing 53.2 kg (117.0 pounds)

Reactions: Fatigue, Vomiting, Stomatitis, Ileus, Nausea, Hepatic Neoplasm Malignant, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-08-03
    End date: 2009-08-18

Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-07-30
    End date: 2009-07-31

Oxycontin
    Dosage: since before nexavar administration
    Administration route: Oral
    Indication: Pain Management
    End date: 2009-08-17

Oxycontin
    Dosage: 160 mg (daily dose), , unknown
    Start date: 2009-08-18
    End date: 2009-08-23

Other drugs received by patient: Sennoside; Sepamit; Gabapentin; Amitriptyline HCL; Keratinamin; Voltaren; Omeprazole; Maglax; Fentanyl-100; Mucosta; Loxonin; Fentanyl-100; Oxycodone Hydrochloride; Anpec



Possible Nexavar side effects in 85 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-23

Patient: 85 year old male, weighing 45.0 kg (99.0 pounds)

Reactions: Death, Amylase Increased, Platelet Count Decreased, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Hirudoid; Losartan Potassium



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-23

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Hypertension, Blood Creatinine Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Urepearl; Pydoxal; Rabeprazole Sodium; Betamethasone Sodium Phosphate; Mobic



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-19

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Blood Creatinine Increased, Hypertension, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Betamethasone Sodium Phosphate; Pydoxal; Rabeprazole Sodium; Mobic; Urepearl



Possible Nexavar side effects in 74 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-19

Patient: 74 year old female

Reactions: Abdominal Pain, Weight Decreased, Hepatic Neoplasm Malignant, Portal Vein Thrombosis, Musculoskeletal Pain, Pyrexia, Headache, Ascites, Hepatic Enzyme Increased, Diarrhoea, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 60 year old male

Reported by a consumer/non-health professional from United States on 2012-07-17

Patient: 60 year old male

Reactions: Cellulitis, Retching, Pyrexia, Erythema, Fall, Diarrhoea, Oedema Peripheral, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Pain Medication



Possible Nexavar side effects in 66 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-16

Patient: 66 year old female

Reactions: Abdominal Pain, Weight Decreased, Blood Urine Present, Skin Exfoliation, Flatulence, Rash, Dysgeusia, Abdominal Discomfort, Hair Texture Abnormal, Diarrhoea, Alopecia, Dermatitis Bullous, Decreased Appetite

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Coumadin; Metformin Hydrochloride



Possible Nexavar side effects in 59 year old male

Reported by a physician from Japan on 2012-07-16

Patient: 59 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Nausea, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Antihypertensives; ALL Other Therapeutic Products



Possible Nexavar side effects in 63 year old male

Reported by a physician from Japan on 2012-07-13

Patient: 63 year old male, weighing 67.5 kg (148.5 pounds)

Reactions: Hyperbilirubinaemia, Vomiting, Nausea, Alanine Aminotransferase Increased, Hepatic Failure, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Dysphonia, Aspartate Aminotransferase Increased, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Maglax; Keratinamin; Norvasc; NEO-Minophagen C; Oxycontin; Loxoprofen; Famotidine; Candesartan Cilexetil; Urso 250; Oxycodone Hydrochloride; Evamyl; NEO-Minophagen C; Laxoberon; Trichlormethiazide; Flivastatin Sodium; Oxycontin; Oxycontin; NEO-Minophagen C



Possible Nexavar side effects in 51 year old male

Reported by a consumer/non-health professional from United States on 2012-07-11

Patient: 51 year old male

Reactions: Aphagia, Pruritus, Nausea, Skin Exfoliation, Rash, Pruritus Genital, Fatigue, Feeling Hot, Rash Maculo-Papular, Decreased Appetite, Blister

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Diuretics



Possible Nexavar side effects in 74 year old male

Reported by a physician from Japan on 2012-07-06

Patient: 74 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Hepatic Neoplasm Malignant, Hyperkalaemia, Disseminated Intravascular Coagulation, International Normalised Ratio Increased, Pyrexia, Hypernatraemia, Diarrhoea, Sepsis, Metastases To Central Nervous System, Decreased Appetite

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Digoxin; Lasix; Oxycontin; Magnesium Oxide; Motilium; Warfarin Sodium; Alosenn; Aldactone; Oxycodone Hydrochloride; Oxycodone Hydrochloride; Polaramine; Prochlorperazine; Lansoprazole



Possible Nexavar side effects in 59 year old male

Reported by a physician from United States on 2012-07-05

Patient: 59 year old male, weighing 126.8 kg (279.0 pounds)

Reactions: Blood Bilirubin Increased, Myalgia, Fatigue, Encephalopathy, Ammonia Increased, Decreased Appetite, Lethargy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Protonix; Hydrochlorothiazide; Losartan Potassium



Possible Nexavar side effects in 64 year old male

Reported by a pharmacist from Japan on 2012-07-02

Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Hepatic Neoplasm Malignant, Diarrhoea, Hyperammonaemia, Palmar-Plantar Erythrodysaesthesia Syndrome, Eczema, Decreased Appetite, Ascites

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 800 mg/day
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-08-06
    End date: 2009-09-08

Nexavar
    Dosage: 400 mg/day
    Administration route: Oral
    Start date: 2009-10-28
    End date: 2009-10-30

Nexavar
    Dosage: 600 mg/day
    Administration route: Oral
    Start date: 2009-10-02
    End date: 2009-10-27

Nexavar
    Dosage: 400 mg/day
    Administration route: Oral
    Start date: 2009-09-09
    End date: 2009-10-01

Other drugs received by patient: Pastaron; Morphine; Fentanyl-100; Aldactone; Rabeprazole Sodium; Mucosta; Ensure [minerals Nos,vitamins Nos]; Hypoca; Aldactone; Lamivudine; Oxycontin; Hepsera; Loxoprofen; Lasix



Possible Nexavar side effects in 74 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-02

Patient: 74 year old female

Reactions: Abdominal Pain Lower, Weight Decreased, Blood Pressure Systolic Increased, Musculoskeletal Pain, Portal Vein Thrombosis, Pyrexia, Headache, Disease Progression, Ascites, Hepatic Enzyme Increased, Diarrhoea, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 81 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-28

Patient: 81 year old male

Reactions: Weight Decreased, Hepatic Neoplasm Malignant, Cystitis, Convulsion, Fatigue, Dehydration, Asthenia, White Blood Cell Count Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 79 year old female

Reported by a pharmacist from Japan on 2012-06-25

Patient: 79 year old female, weighing 47.0 kg (103.4 pounds)

Reactions: Palmar-Plantar Erythrodysaesthesia Syndrome, Lumbar Vertebral Fracture, Epilepsy, Transient Ischaemic Attack, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-09-06
    End date: 2011-09-12

Nexavar
    Dosage: 200 mg, qd
    Start date: 2011-09-13
    End date: 2011-11-02

Nexavar
    Dosage: 200 mg, qd
    Start date: 2012-01-11
    End date: 2012-01-18

Other drugs received by patient: Ursamic; Lasix; Trichlormethiazide; Lansoprazole; Tolterodine Tartrate; Olmesartan Medoxomil; Amlodipine



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-06-22

Patient: 70 year old male

Reactions: Haemoglobin Decreased, Gastric Ulcer Haemorrhage, Duodenal Ulcer, Gastric Ulcer, Decreased Appetite, Faeces Discoloured

Drug(s) suspected as cause:
Nexavar



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