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Nexavar (Sorafenib) - Fatigue - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Fatigue (194)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include fatigue. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 194   Next >>

Possible Nexavar side effects in 54 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27

Patient: 54 year old male

Reactions: Blood Pressure Increased, Weight Decreased, Nausea, Pain in Extremity, Hypotension, Rash, Skin Irritation, Frequent Bowel Movements, Fatigue, Diarrhoea, Gait Disturbance, Decreased Appetite

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 59 year old female

Reported by a physician from United States on 2012-08-27

Patient: 59 year old female, weighing 59.0 kg (129.7 pounds)

Reactions: Weight Decreased, Peripheral Coldness, Vomiting, Glossodynia, Nausea, Pain, Rash, Hyperhidrosis, Constipation, Erythema, Fatigue, Diarrhoea, Dehydration, Feeling Hot, Dizziness, Cold Sweat, Blister

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, daily
    Administration route: Oral
    Start date: 2012-07-14

Nexavar
    Dosage: 400 mg, qd
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-09

Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-05-19

Nexavar
    Dosage: 400 mg am and 200 mg pm
    End date: 2012-07-11



Possible Nexavar side effects in 59 year old male

Reported by a physician from France on 2012-08-23

Patient: 59 year old male, weighing 120.0 kg (264.0 pounds)

Reactions: Fatigue, Hepatic Neoplasm Malignant, Hepatic Failure, Encephalopathy, Hepatic Cirrhosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Propranolol; Glucophage; Lorazepam



Possible Nexavar side effects in 55 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23

Patient: 55 year old male

Reactions: Jaundice, Abdominal Pain, Hyperkalaemia, Chills, Mental Status Changes, Pyrexia, Loss of Consciousness, Death, Hepatic Encephalopathy, Fatigue, Cholangitis, Pleural Effusion, Thrombocytopenia, Renal Failure Acute, Nausea, Malnutrition, Urinary Tract Infection, Anaemia, Hyponatraemia, Rash, Bacteraemia, Dehydration, Ammonia Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-25
    End date: 2012-06-05

Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-06-01

Other drugs received by patient: Lorazepam; Diphenoxylate HCL and Atropine Sulfate; Lortab; Lasix; Albuterol; Aldactone; Protonix



Possible Nexavar side effects in 61 year old male

Reported by a consumer/non-health professional from China on 2012-08-22

Patient: 61 year old male, weighing 51.0 kg (112.2 pounds)

Reactions: Fatigue, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Erlotinib Hydrochloride
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2010-09-28
    End date: 2012-07-25

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2010-01-25
    End date: 2012-08-01

Other drugs received by patient: Ascorbic Acid; Herbal Preparation; Vitamin B Complex CAP



Possible Nexavar side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22

Patient: 58 year old female

Reactions: Fatigue, Arthralgia, Abasia, DRY Skin, Blister

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 58 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20

Patient: 58 year old male

Reactions: Weight Decreased, Fatigue, Neck Pain, Musculoskeletal Stiffness, Blood Glucose Fluctuation, Gallbladder Disorder, Gastrooesophageal Reflux Disease, Muscle Spasms, Decreased Appetite, Back Pain, Vomiting, Nausea, DRY Skin, Anxiety, Insomnia, Asthenia

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 53 year old male

Reported by a physician from Switzerland on 2012-08-20

Patient: 53 year old male

Reactions: Fatigue, Dyspnoea, Mouth Haemorrhage, Metastases To Bone, Epistaxis

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 53 year old male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 53 year old male

Reactions: Confusional State, Agitation, Dysphagia, Pain, Anaemia, Failure To Thrive, Hypokalaemia, Death, Fatigue, Fluid Intake Reduced, Asthenia, Decreased Appetite, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg am, 200 mg pm x 21days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-07

Xeloda
    Dosage: 1500 mg am, 1650 mg pm x 14 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2012-06-22
    End date: 2012-08-01

Other drugs received by patient: Roxicodone; Compazine; Ferrous Fumarate; MS Contin; Phenergan HCL; Prinzide; Multi-Vitamin; Compazine



Possible Nexavar side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 70 year old male

Reactions: Blood Pressure Increased, Weight Decreased, Pyrexia, Abdominal Pain Upper, Eating Disorder, Fatigue, Blood Phosphorus Decreased, Chest Pain, Pancreatic Enzymes Increased, Gastrooesophageal Reflux Disease, White Blood Cell Count Increased, Blister, Infrequent Bowel Movements

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-07-01
    End date: 2012-07-01

Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-07-01

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-07-10
    End date: 2012-07-28

Other drugs received by patient: Losartan Potassium



Possible Nexavar side effects in 56 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 56 year old male

Reactions: Fatigue, Pain in Extremity, Furuncle, Skin Disorder, Rash, Skin Infection, Erythema

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg am; 400mg pm

Nexavar
    Dosage: 200 mg am, 400 mg pm
    Indication: Ureteral Neoplasm
    Start date: 2011-09-01
    End date: 2012-06-12



Possible Nexavar side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: 59 year old female

Reactions: Weight Decreased, Peripheral Coldness, Glossodynia, Pain, Constipation, Erythema, Hyperhidrosis, Fatigue, Feeling Hot, Dizziness, Cold Sweat, Blister, Vomiting, Nausea, Rash, Diarrhoea, Dehydration

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-05-19

Nexavar
    Dosage: 400 mg am and 200 mg pm
    End date: 2012-07-11

Nexavar
    Dosage: 400 mg, daily
    Administration route: Oral
    Start date: 2012-07-14

Nexavar
    Dosage: 400 mg, qd
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-09



Possible Nexavar side effects in 62 year old male

Reported by a physician from Japan on 2012-08-08

Patient: 62 year old male, weighing 57.0 kg (125.4 pounds)

Reactions: Fatigue, Dyspnoea, Diarrhoea, Bone Marrow Failure, Acute Respiratory Distress Syndrome, Decreased Appetite

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 800 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-03-10
    End date: 2012-03-20

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-04-01
    End date: 2012-05-01

Nexavar
    Dosage: 400 mg, qod
    Start date: 2012-04-28
    End date: 2012-04-30

Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-03-29
    End date: 2012-04-27

Other drugs received by patient: Silece; Risperidone; Zometa; Fentanyl Citrate; Lyrica; Loxonin; Lamivudine; Hepsera



Possible Nexavar side effects in 65 year old male

Reported by a consumer/non-health professional from United States on 2012-08-07

Patient: 65 year old male, weighing 72.6 kg (159.6 pounds)

Reactions: Glossodynia, Dyspnoea, Visual Field Defect, Pain in Extremity, Pain, Musculoskeletal Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Fatigue, Vitreous Floaters, Dizziness, Vision Blurred, Lacrimation Increased, Blood Pressure Abnormal, Asthenia, Arthritis

Drug(s) suspected as cause:
Nexavar
    Dosage: unk
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2012-04-24
    End date: 2012-05-21

Sutent
    Dosage: 50 mg, cyclic (50mg for the first 42 day cycle)
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2012-06-26

Other drugs received by patient: Symbicort; Nasonex; Ascorbic Acid; Refresh; Lotemax; Mucinex; Mobic; Chondroitin / Glucosamine; Proventil Gentlehaler



Possible Nexavar side effects in 70 year old female

Reported by a physician from Japan on 2012-08-06

Patient: 70 year old female, weighing 30.0 kg (66.0 pounds)

Reactions: Fatigue, Nausea, Metastases To Lung, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, qd
    Administration route: Oral

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral



Possible Nexavar side effects in 49 year old female

Reported by a consumer/non-health professional from United States on 2012-08-02

Patient: 49 year old female

Reactions: Back Pain, Aphagia, Vomiting, Skin Exfoliation, Nausea, Pain of Skin, Pain, Skin Burning Sensation, Constipation, Abdominal Pain Upper, Fatigue

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-01-01

Nexavar
    Dosage: 400 mg, bid

Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-01-01

Other drugs received by patient: Morphine Sulfate; Levaquin



Possible Nexavar side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01

Patient: 62 year old female

Reactions: Fatigue, Atrial Fibrillation, DRY Skin

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-09-01
    End date: 2011-01-01

Nexavar
    Dosage: 200 mg, qod (1 pill every other day)
    Start date: 2012-04-01



Possible Nexavar side effects in 55 year old male

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient: 55 year old male

Reactions: Jaundice, Nausea, Pyrexia, Rash, Death, Fatigue, Dehydration, Ammonia Increased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 57 year old male

Reported by a physician from United States on 2012-07-30

Patient: 57 year old male

Reactions: Death, Fatigue, Renal Disorder, Nausea, Hypersomnia

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 75 year old male

Reported by a physician from United States on 2012-07-30

Patient: 75 year old male

Reactions: Chest Discomfort, Dysphagia, Nausea, Pyrexia, Disorientation, Hypoaesthesia, Eructation, Fatigue, Malaise, Diarrhoea, Abdominal Distension, Gastrooesophageal Reflux Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: unk
    Start date: 2012-06-11
    End date: 2012-07-19

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Start date: 2012-07-06
    End date: 2012-07-09

Nexavar
    Dosage: daily dose 600 mg (200 in am 400 in pm)
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-06-11
    End date: 2012-06-22

Nexavar
    Dosage: unk
    Start date: 2012-07-21

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-07-02
    End date: 2012-07-05

Other drugs received by patient: Glucophage



Possible Nexavar side effects in 59 year old male

Reported by a physician from United States on 2012-07-27

Patient: 59 year old male, weighing 126.8 kg (279.0 pounds)

Reactions: Myalgia, Blood Bilirubin Increased, Fatigue, Ammonia Increased, Encephalopathy, Decreased Appetite, Lethargy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Hydrochlorothiazide; Losartan Potassium and Hydrochlorothiazide; Protonix



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-25

Patient: male, weighing 72.6 kg (159.6 pounds)

Reactions: Pain in Extremity, Visual Field Defect, Pain, Musculoskeletal Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Fatigue, Dizziness, Lacrimation Increased, Asthenia, Arthritis

Drug(s) suspected as cause:
Nexavar
    Dosage: unk
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2012-04-24
    End date: 2012-05-21

Sutent
    Dosage: 50 mg, cyclic (50mg for the first 42 day cycle)
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2012-06-26

Other drugs received by patient: Refresh; Proventil Gentlehaler; Nasonex; Ascorbic Acid; Symbicort; Lotemax; Mucinex; Chondroitin / Glucosamine; Mobic



Possible Nexavar side effects in 59 year old female

Reported by a consumer/non-health professional from United States on 2012-07-25

Patient: 59 year old female

Reactions: Peripheral Coldness, Weight Decreased, Glossodynia, Vomiting, Nausea, Pain, Rash, Hyperhidrosis, Constipation, Erythema, Fatigue, Diarrhoea, Feeling Hot, Dehydration, Dizziness, Cold Sweat

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-05-19

Nexavar
    Dosage: 400 mg, qd
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-09

Nexavar
    Dosage: 400 mg am and 200 mg pm
    End date: 2012-07-11



Possible Nexavar side effects in 75 year old male

Reported by a physician from Japan on 2012-07-24

Patient: 75 year old male, weighing 53.2 kg (117.0 pounds)

Reactions: Fatigue, Vomiting, Stomatitis, Ileus, Nausea, Hepatic Neoplasm Malignant, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-08-03
    End date: 2009-08-18

Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-07-30
    End date: 2009-07-31

Oxycontin
    Dosage: since before nexavar administration
    Administration route: Oral
    Indication: Pain Management
    End date: 2009-08-17

Oxycontin
    Dosage: 160 mg (daily dose), , unknown
    Start date: 2009-08-18
    End date: 2009-08-23

Other drugs received by patient: Sennoside; Sepamit; Gabapentin; Amitriptyline HCL; Keratinamin; Voltaren; Omeprazole; Maglax; Fentanyl-100; Mucosta; Loxonin; Fentanyl-100; Oxycodone Hydrochloride; Anpec



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-23

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Hypertension, Blood Creatinine Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Urepearl; Pydoxal; Rabeprazole Sodium; Betamethasone Sodium Phosphate; Mobic



Possible Nexavar side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-20

Patient: 74 year old male

Reactions: Chest Discomfort, Dysphagia, Disorientation, Pyrexia, Hypoaesthesia, Fatigue, Malaise, Abdominal Distension, Gastrooesophageal Reflux Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 600 mg (200 in am 400 in pm)
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-06-11
    End date: 2012-06-22

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-07-02
    End date: 2012-07-05

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Start date: 2012-07-06
    End date: 2012-07-09

Other drugs received by patient: Glucophage



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-20

Patient: male

Reactions: Fatigue, Diarrhoea, Chills, Hypertension, Tremor, Feeling Cold

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Vytorin; Lantus



Possible Nexavar side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-20

Patient: 59 year old female

Reactions: Weight Decreased, Peripheral Coldness, Vomiting, Glossodynia, Nausea, Rash, Erythema, Constipation, Hyperhidrosis, Fatigue, Diarrhoea, Dehydration, Feeling Hot, Dizziness, Cold Sweat

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd
    End date: 2012-07-11

Nexavar
    Dosage: 400 mg, qd
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-05-09

Nexavar
    Dosage: 400 mg, bid
    Start date: 2012-05-19



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-19

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Blood Creatinine Increased, Hypertension, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Betamethasone Sodium Phosphate; Pydoxal; Rabeprazole Sodium; Mobic; Urepearl



Possible Nexavar side effects in 70 year old male

Reported by a physician from United States on 2012-07-17

Patient: 70 year old male

Reactions: Fatigue, Hepatic Pain, Painful Respiration, Asthenia, Hypersomnia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-06-01
    End date: 2012-01-01

Nexavar
    Dosage: 400 mg, bid

Nexavar
    Dosage: 2 df, unk
    Indication: Gastrointestinal Stromal Tumour
    Start date: 2012-06-06



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