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Nexavar (Sorafenib) - Hypertension - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypertension (132)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include hypertension. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 132   Next >>

Possible Nexavar side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-24

Patient: 73 year old female, weighing 48.0 kg (105.6 pounds)

Reactions: Hyperbilirubinaemia, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, General Physical Health Deterioration, Encephalopathy, Dizziness, Hypertension, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2010-01-08
    End date: 2010-01-10

Nexavar
    Dosage: 800 mg, qd
    Administration route: Oral
    Start date: 2010-01-13
    End date: 2010-01-19

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-01-20
    End date: 2010-03-02

Other drugs received by patient: Aldactone; Shakuyakukanzoutou; Omeprazole; Urso 250; Medicon; Allegra; Acetaminophen; Onealfa



Possible Nexavar side effects in 67 year old male

Reported by a consumer/non-health professional from Brazil on 2012-08-21

Patient: 67 year old male, weighing 75.0 kg (165.0 pounds)

Reactions: Speech Disorder, Gait Disturbance, Hypertension, Asthenia, Blood Glucose Abnormal, Convulsion

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient possibly interacting with the suspect drug:
Glimepiride
    Dosage: 4 mg, bid
    Administration route: Oral
    Indication: Diabetes Mellitus

Metformin HCL
    Dosage: 85 mg, tid
    Administration route: Oral
    Indication: Diabetes Mellitus

Metformin HCL
    Dosage: 85 mg, tid
    Administration route: Oral

Propranolol
    Dosage: 40 mg, bid
    Administration route: Oral
    Indication: Hypertension
    Start date: 2004-01-01

Other drugs received by patient: Levothyroxine Sodium; Doxazosin Mesylate



Possible Nexavar side effects in 79 year old male

Reported by a physician from Japan on 2012-08-16

Patient: 79 year old male, weighing 56.0 kg (123.2 pounds)

Reactions: Proteinuria, Hypertension, Nephrotic Syndrome, Haemorrhage Subcutaneous

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 400 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-20
    End date: 2011-03-23

Nexavar
    Dosage: daily dose 200 mg
    Start date: 2011-03-24
    End date: 2011-07-07

Other drugs received by patient: Diovan; Hirudoid; Doxazosin Mesylate; Tagamet; Depas; Maglax; Lasix; Acetylol; Cibenol; Zolpidem; Urinorm; Adalat CC; Doxazosin Mesylate; Irgas; Gorei-SAN; Hyalein; Loxonin; Lasix; Lasix; Azulene-Glutamine; Cephadol



Possible Nexavar side effects in 80 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-14

Patient: 80 year old female

Reactions: Abdominal Pain, Hypertension

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Aspirin
    Dosage: daily dose 100 mg
    Administration route: Oral
    Start date: 2007-01-01
    End date: 2008-11-04

Nexavar
    Dosage: daily dose 400 mg
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2008-10-07
    End date: 2008-10-14

Other drugs received by patient: Nebivolol HCL; Tramadol HCL



Possible Nexavar side effects in 59 year old male

Reported by a physician from Japan on 2012-08-02

Patient: 59 year old male

Reactions: Sepsis, Palmar-Plantar Erythrodysaesthesia Syndrome, Platelet Count Decreased, Jaundice Cholestatic, Hypertension

Adverse event resulted in: death

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2009-10-07
    End date: 2009-10-01

Nexavar
    Dosage: 400 mg, unk
    Administration route: Oral
    Start date: 2009-10-01
    End date: 2009-12-01



Possible Nexavar side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-08-02

Patient: 61 year old male

Reactions: Abdominal Pain, Phlebitis, Chest Discomfort, Glossodynia, Palmar-Plantar Erythrodysaesthesia Syndrome, Pyrexia, Abdominal Pain Upper, Abscess Intestinal, Oral Pain, Dizziness, Vision Blurred, Enterocolitis, Hypertension, Metastases To Bone

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 800 mg, unk
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-08-08
    End date: 2011-09-03

Nexavar
    Dosage: 600 mg, qd
    End date: 2012-07-23

Nexavar
    Dosage: 400 mg, qd
    Start date: 2011-10-05

Nexavar
    Dosage: 800 mg, unk
    Start date: 2011-09-14
    End date: 2011-10-04

Other drugs received by patient: Bisoprolol Fumarate; Amlodipine Besylate; Hydrocortone; Omeprazole; Multi-Vitamin; Bisoprolol Fumarate; Legalon; Fludrocortisone Acetate; Calcium



Possible Nexavar side effects in 71 year old male

Reported by a physician from Japan on 2012-08-02

Patient: 71 year old male, weighing 67.0 kg (147.4 pounds)

Reactions: Hypertension, Ascites

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 400 mg
    Start date: 2012-04-27

Nexavar
    Dosage: daily dose 400 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2012-02-03
    End date: 2012-04-09

Other drugs received by patient: Shakuyakukanzoutou; Adalat CC; Adalat CC; Miraclid; Lasix; Livact; Pastaron; Pursennid; Omeprazole; Adalat CC; Magmitt; Albumin (Human); Portolac



Possible Nexavar side effects in 67 year old female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: 67 year old female

Reactions: Chills, Adverse Drug Reaction, Pyrexia, Oropharyngeal Spasm, Faeces Discoloured, Herpes Zoster, Dyspepsia, Cranial Nerve Disorder, Alpha 1 Foetoprotein Increased, Dizziness, Vulvovaginal Rash, Nausea, Pain of Skin, Musculoskeletal Discomfort, Skin Disorder, Rash, Hepatic Enzyme Increased, Diarrhoea, Thyroid Disorder, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, daily
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant non-Resectable
    Start date: 2012-04-03

Nexavar

Nexavar
    Dosage: 200 mg, bid
    Start date: 2012-04-30
    End date: 2012-05-15

Nexavar
    Dosage: 400 mg, bid
    End date: 2012-05-15

Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-05-21
    End date: 2012-05-22

Other drugs received by patient: Antihypertensives; Cardiac Therapy



Possible Nexavar side effects in 74 year old male

Reported by a physician from Japan on 2012-07-27

Patient: 74 year old male

Reactions: Bradycardia, Hypertension

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 79 year old male

Reported by a physician from Japan on 2012-07-24

Patient: 79 year old male, weighing 56.0 kg (123.2 pounds)

Reactions: Proteinuria, Hypertension, Haemorrhage Subcutaneous

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 400 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-20
    End date: 2011-03-23

Nexavar
    Dosage: daily dose 200 mg
    Start date: 2011-03-24
    End date: 2011-07-07

Other drugs received by patient: Azulene-Glutamine; Hirudoid; Diovan; Acetylol; Cibenol; Depas; Urinorm; Lasix; Loxonin; Lasix; Cephadol; Tagamet; Maglax; Doxazosin Mesylate; Hyalein; Zolpidem; Doxazosin Mesylate; Adalat CC; Irgas; Gorei-SAN



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-23

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Hypertension, Blood Creatinine Increased, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Urepearl; Pydoxal; Rabeprazole Sodium; Betamethasone Sodium Phosphate; Mobic



Possible Nexavar side effects in 72 year old male

Reported by a physician from Japan on 2012-07-20

Patient: 72 year old male, weighing 61.2 kg (134.7 pounds)

Reactions: Diabetes Mellitus, Hyponatraemia, Pyrexia, Transaminases Increased, Ascites, Hepatic Encephalopathy, Dysphonia, Hypertension, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lasix
    Dosage: 20 mg, ow
    Start date: 2010-11-01
    End date: 2010-01-01

Lasix
    Dosage: 20 mg, qd
    Administration route: Oral
    Start date: 2011-01-14

Lasix
    Dosage: 60 mg, qd
    Administration route: Oral
    Start date: 2010-09-28
    End date: 2010-10-18

Lasix
    Dosage: 20 mg, qd
    Administration route: Oral
    End date: 2010-09-13

Lasix
    Dosage: 20 mg, once
    Start date: 2010-11-15
    End date: 2010-11-15

Lasix
    Dosage: 40 mg, qd
    Administration route: Oral
    Start date: 2010-10-19
    End date: 2011-01-11

Lasix
    Dosage: 40 mg, qd
    Administration route: Oral
    Start date: 2010-09-14
    End date: 2010-09-27

Nexavar
    Dosage: 400 mg, qod
    Administration route: Oral
    Start date: 2010-12-07
    End date: 2011-01-10

Nexavar
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2010-08-04
    End date: 2010-11-15

Nexavar
    Dosage: 400 mg, qod
    Administration route: Oral
    Start date: 2011-03-22

Other drugs received by patient: Hirudoid; Novorapid; Aldactone; Novorapid; Kanamycin; Basen; Famotidine; Novorapid; BIO Three [clostrid Butyricum,lactobac Acidoph,saccharom Boular]; Magnesium Oxide; Urso 250; Amaryl; Aldactone; Aldactone; Albumin (Human); Amaryl; Aldactone; Aldactone; Myser; Novorapid; Levofloxacin; Shakuyakukanzoutou; Amaryl; Hochuuekkitou; Livact; Albumin (Human)



Possible Nexavar side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-20

Patient: male

Reactions: Fatigue, Diarrhoea, Chills, Hypertension, Tremor, Feeling Cold

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Vytorin; Lantus



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-07-19

Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)

Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Blood Creatinine Increased, Hypertension, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar

Other drugs received by patient: Betamethasone Sodium Phosphate; Pydoxal; Rabeprazole Sodium; Mobic; Urepearl



Possible Nexavar side effects in 62 year old female

Reported by a physician from Japan on 2012-07-18

Patient: 62 year old female, weighing 50.0 kg (110.0 pounds)

Reactions: Hepatic Function Abnormal, Amylase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, Nail Ridging, Pyrexia, Hypophosphataemia, Diarrhoea, Lipase Increased, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg/day
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-10-19
    End date: 2012-04-25

Nexavar
    Dosage: 200 mg, qod
    Administration route: Oral
    Start date: 2012-04-26
    End date: 2012-05-09

Other drugs received by patient: Lendormin; Urso 250; Zolpidem; Livact; Aminoleban EN; Aminoleban EN; Eurax; Olmesartan Medoxomil; Primperan TAB; Aminoleban EN; Allegra; Loxonin; Olmesartan Medoxomil; Olmesartan Medoxomil; Urepearl



Possible Nexavar side effects in 69 year old male

Reported by a physician from Japan on 2012-07-17

Patient: 69 year old male

Reactions: Hepatic Function Abnormal, Haematuria, Hypothyroidism, Hypertension

Drug(s) suspected as cause:
Nexavar
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2009-01-13
    End date: 2009-03-13

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Start date: 2009-09-16
    End date: 2012-06-01

Nexavar
    Dosage: 400 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-04-06
    End date: 2009-04-12

Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-04-13
    End date: 2009-08-18

Nexavar
    Dosage: 400 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-08-19
    End date: 2009-09-15

Other drugs received by patient: Ferric Hydroxide Polymaltose Complex; Lamisil; Adona; Transamine CAP; Almarl; Levothyroxine Sodium; Levothyroxine Sodium; Felodipine



Possible Nexavar side effects in 84 year old female

Reported by a physician from Japan on 2012-07-16

Patient: 84 year old female

Reactions: Pleural Effusion, Platelet Count Decreased, Hypertension, Ascites

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd on day 1- 28
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-05-25

Nexavar
    Dosage: 200 mg, qd
    Administration route: Oral
    End date: 2012-02-01

Other drugs received by patient: Cisplatin; Cisplatin



Possible Nexavar side effects in 69 year old male

Reported by a physician from Japan on 2012-07-09

Patient: 69 year old male

Reactions: Hepatic Function Abnormal, Haematuria, Hypothyroidism, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-08-19
    End date: 2009-09-15

Nexavar
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2009-01-13
    End date: 2009-03-13

Nexavar
    Dosage: 400 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-04-06
    End date: 2009-04-12

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Start date: 2009-09-16
    End date: 2012-06-01

Nexavar
    Dosage: 800 mg (daily dose), , oral
    Administration route: Oral
    Start date: 2009-04-13
    End date: 2009-08-18

Other drugs received by patient: Ferric Hydroxide Polymaltose Complex; Transamine CAP; Lamisil; Levothyroxine Sodium; Adona; Felodipine; Almarl; Levothyroxine Sodium



Possible Nexavar side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-05

Patient: 67 year old female

Reactions: Nausea, Pain of Skin, Musculoskeletal Discomfort, Skin Disorder, Vulvovaginal Discomfort, Rash, Hepatic Enzyme Increased, Oropharyngeal Spasm, Herpes Zoster, Diarrhoea, Dyspepsia, Cranial Nerve Disorder, Alpha 1 Foetoprotein Increased, Thyroid Disorder, Dizziness, Unevaluable Event, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2012-05-21
    End date: 2012-05-22

Nexavar
    Dosage: 400 mg, bid
    End date: 2012-05-15

Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant non-Resectable
    Start date: 2012-04-30
    End date: 2012-05-15

Other drugs received by patient: Cardiac Therapy; Antihypertensives



Possible Nexavar side effects in 54 year old male

Reported by a physician from Japan on 2012-06-29

Patient: 54 year old male

Reactions: Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Ascites, Haemoglobin Decreased, Diarrhoea, Oedema Peripheral, Liver Function Test Abnormal, Feeling Hot, Hypertension, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-08-18
    End date: 2011-11-17

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2011-09-08
    End date: 2011-11-17

Nexavar
    Dosage: 200 mg, qd
    Administration route: Oral
    Start date: 2011-12-08



Possible Nexavar side effects in 67 year old female

Reported by a physician from United States on 2012-06-28

Patient: 67 year old female

Reactions: Nausea, Pain of Skin, Skin Disorder, Musculoskeletal Discomfort, Vulvovaginal Discomfort, Rash, Hepatic Enzyme Increased, Herpes Zoster, Oropharyngeal Spasm, Diarrhoea, Dyspepsia, Cranial Nerve Disorder, Alpha 1 Foetoprotein Increased, Thyroid Disorder, Dizziness, Unevaluable Event, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant non-Resectable
    Start date: 2012-04-30

Nexavar
    Dosage: 400 mg, bid
    End date: 2012-05-15

Other drugs received by patient: Antihypertensives; Cardiac Therapy



Possible Nexavar side effects in 48 year old male

Reported by a pharmacist from Japan on 2012-06-25

Patient: 48 year old male

Reactions: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypophosphataemia, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Myocardial Infarction, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Candesartan Cilexetil
    Dosage: unk
    Administration route: Oral
    Start date: 2009-12-21

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-02-12
    End date: 2010-04-12

Nexavar
    Dosage: daily dose: 800 mg
    Administration route: Oral
    Start date: 2010-04-13
    End date: 2012-06-01

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2009-11-09
    End date: 2010-01-08

Other drugs received by patient: Urepearl



Possible Nexavar side effects in 87 year old female

Reported by a physician from Japan on 2012-06-22

Patient: 87 year old female

Reactions: Pleural Effusion, Platelet Count Decreased, Hypertension, Ascites

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd on day 1- 28
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-05-25

Nexavar
    Dosage: 200 mg, qd
    Administration route: Oral
    End date: 2012-02-01

Other drugs received by patient: Cisplatin; Cisplatin



Possible Nexavar side effects in 61 year old male

Reported by a physician from United States on 2012-06-21

Patient: 61 year old male

Reactions: Pneumonia, Hypertension, Feeling Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 79 year old male

Reported by a physician from Japan on 2012-06-21

Patient: 79 year old male, weighing 56.0 kg (123.2 pounds)

Reactions: Proteinuria, Hypertension, Haemorrhage Subcutaneous

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: daily dose 400 mg
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-01-20
    End date: 2011-03-23

Nexavar
    Dosage: daily dose 200 mg
    Start date: 2011-03-24
    End date: 2011-07-07

Other drugs received by patient: Tagamet; Gorei-SAN; Depas; Loxonin; Diovan; Irgas; Hyalein; Hirudoid; Lasix; Adalat CC; Lasix; Doxazosin Mesylate; Doxazosin Mesylate; Azulene-Glutamine; Cephadol; Zolpidem; Maglax; Urinorm; Acetylol; Cibenol



Possible Nexavar side effects in 48 year old male

Reported by a physician from Japan on 2012-06-14

Patient: 48 year old male

Reactions: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypophosphataemia, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Myocardial Infarction, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-02-12

Nexavar
    Dosage: 800 mg
    Administration route: Oral

Nexavar
    Dosage: 400 mg, bid
    Administration route: Oral
    Indication: Renal Cell Carcinoma
    Start date: 2009-11-09
    End date: 2010-01-08



Possible Nexavar side effects in 67 year old female

Reported by a physician from United States on 2012-06-13

Patient: 67 year old female

Reactions: Nausea, Pain of Skin, Musculoskeletal Discomfort, Skin Disorder, Rash, Vulvovaginal Discomfort, Oropharyngeal Spasm, Herpes Zoster, Dyspepsia, Diarrhoea, Dizziness, Thyroid Disorder, Feeling Abnormal, Hypertension

Drug(s) suspected as cause:
Nexavar
    Dosage: 400 mg, bid
    End date: 2012-05-01

Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant non-Resectable
    Start date: 2012-04-30



Possible Nexavar side effects in 77 year old male

Reported by a physician from Japan on 2012-06-08

Patient: 77 year old male

Reactions: Liver Function Test Abnormal, Platelet Count Decreased, Hypertension, Hepatic Rupture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nexavar



Possible Nexavar side effects in 67 year old female

Reported by a physician from United States on 2012-06-08

Patient: 67 year old female

Reactions: Nausea, Pain of Skin, Musculoskeletal Discomfort, Skin Disorder, Rash, Vulvovaginal Discomfort, Oropharyngeal Spasm, Dyspepsia, Diarrhoea, Thyroid Disorder, Dizziness, Hypertension, Feeling Abnormal

Drug(s) suspected as cause:
Nexavar
    Dosage: 200 mg, bid
    Indication: Hepatic Neoplasm Malignant non-Resectable
    Start date: 2012-04-30

Nexavar
    Dosage: 400 mg, bid
    End date: 2012-05-01



Possible Nexavar side effects in 70 year old male

Reported by a physician from Japan on 2012-06-06

Patient: 70 year old male

Reactions: Hypertension, Gastric Ulcer, Oesophageal Varices Haemorrhage, Haematemesis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Loxonin
    Dosage: unk
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2011-01-01

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-04-17

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-04-27
    End date: 2012-05-28

Nexavar
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Hepatic Neoplasm Malignant
    Start date: 2011-12-02
    End date: 2012-03-29



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