Index of reports
> Cases with Therapeutic Response Decreased (281)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nplate (Romiplostim Subcutaneous) where reactions include therapeutic response decreased. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 281 Next >>
Possible Nplate side effects in 49 year old male
Reported by a physician from Egypt on 2012-08-27
Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)
Reactions: Therapeutic Response Decreased, Surgery, Post Procedural Complication, Bronchitis, Nosocomial Infection, Preoperative Care
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Dosage: 2 mug/kg, qwk
Nplate
Dosage: 7 mug/kg, qwk
Nplate
Dosage: 1 mug/kg, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Other drugs received by patient: Kanakion; Folic Acid; Selenium ACE
Possible Nplate side effects in 62 year old male
Reported by a consumer/non-health professional from United States on 2012-08-23
Patient: 62 year old male, weighing 91.1 kg (200.4 pounds)
Reactions: Therapeutic Response Decreased, Arthralgia, Treatment Failure
Drug(s) suspected as cause:
Nplate
Dosage: 10 mug, qwk
Indication: Autoimmune Thrombocytopenia
Start date: 2011-11-28
End date: 2012-07-19
Nplate
Dosage: 9 mug/kg, unk
Other drugs received by patient: Losartan Potassium
Possible Nplate side effects in 14 year old female
Reported by a physician from United States on 2012-08-23
Patient: 14 year old female, weighing 99.6 kg (219.1 pounds)
Reactions: Abdominal Pain, Viral Infection, Body Temperature Increased, Nausea, Blood Lactate Dehydrogenase Increased, Underdose, Purpura, Pyrexia, Haemolysis, RED Blood Cell Morphology Abnormal, Therapeutic Response Decreased, Injection Site Extravasation, Poor Venous Access, Blood Smear Test Abnormal, Menorrhagia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Dosage: 300 mug, qwk
Start date: 2011-02-07
End date: 2011-02-17
Nplate
Dosage: 600 mug, qwk
Start date: 2011-03-10
End date: 2011-03-17
Nplate
Dosage: 100 mug, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2010-12-14
End date: 2010-12-28
Nplate
Dosage: 250 mug, qwk
Start date: 2011-01-31
End date: 2011-02-07
Nplate
Dosage: 500 mug, qwk
Start date: 2011-03-02
End date: 2011-03-02
Nplate
Dosage: 200 mug, qwk
Start date: 2010-12-28
End date: 2011-01-04
Nplate
Dosage: 200 mug, qwk
Start date: 2011-01-24
End date: 2011-01-31
Nplate
Dosage: 400 mug, qwk
Start date: 2011-02-17
End date: 2011-02-17
Other drugs received by patient: Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Dexamethasone; Prednisone TAB
Possible Nplate side effects in female
Reported by a physician from United Kingdom on 2012-08-22
Patient: female
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 82 year old female
Reported by a consumer/non-health professional from United States on 2012-08-20
Patient: 82 year old female, weighing 41.4 kg (91.0 pounds)
Reactions: Therapeutic Response Decreased, Thrombocytopenia
Drug(s) suspected as cause:
Nplate
Dosage: 4 mug/kg, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2011-11-15
Nplate
Dosage: 168 mug, qwk
End date: 2012-08-07
Other drugs received by patient: Imdur; Nexium; Magnesium Oxide; Iviglob-EX; Iviglob-EX; Boniva; Aspirin; Vitamin D; Calcium Carbonate; Rituxan; Metoprolol Tartrate; Rituxan; Rituxan; Rituxan; Iviglob-EX; Capoten; Lipitor; Rituxan; Iviglob-EX
Possible Nplate side effects in 52 year old male
Reported by a physician from United States on 2012-08-17
Patient: 52 year old male
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in male
Reported by a physician from United Kingdom on 2012-08-17
Patient: male, weighing 100.0 kg (220.0 pounds)
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: NEO-Mercazole TAB
Possible Nplate side effects in 82 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13
Patient: 82 year old female
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Dosage: 4 mug/kg, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2011-11-15
Nplate
Dosage: 1 mug/kg, unk
Other drugs received by patient: Magnesium Oxide; Metoprolol; Imdur; Capoten; Calcium Carbonate; Vitamin D; Lipitor; Nexium; Boniva; Aspirin
Possible Nplate side effects in 5 year old male
Reported by a physician from Egypt on 2012-08-10
Patient: 5 year old male
Reactions: Therapeutic Response Decreased, Bronchitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Dosage: 7 mug/kg, qwk
Nplate
Dosage: 1 mug/kg, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Nplate
Dosage: 2 mug/kg, qwk
Possible Nplate side effects in 15 year old female
Reported by a physician from United States on 2012-08-09
Patient: 15 year old female, weighing 99.6 kg (219.1 pounds)
Reactions: RED Blood Cell Morphology Abnormal, Therapeutic Response Decreased, Injection Site Extravasation, Blood Lactate Dehydrogenase Increased, Underdose, Blood Smear Test Abnormal, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Dosage: 100 mug, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2010-12-14
End date: 2010-12-28
Nplate
Dosage: 200 mug, qwk
Start date: 2010-12-28
End date: 2011-01-04
Nplate
Dosage: 200 mug, qwk
Start date: 2011-01-24
End date: 2011-01-31
Nplate
Dosage: 300 mug, qwk
Start date: 2011-02-07
End date: 2011-02-17
Nplate
Dosage: 500 mug, qwk
Start date: 2011-03-02
End date: 2011-03-02
Nplate
Dosage: 250 mug, qwk
Start date: 2011-01-31
End date: 2011-02-07
Nplate
Dosage: 400 mug, qwk
Start date: 2011-02-17
End date: 2011-02-17
Nplate
Dosage: 600 mug, qwk
Start date: 2011-03-10
End date: 2011-03-17
Other drugs received by patient: Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Dexamethasone
Possible Nplate side effects in 70 year old male
Reported by a physician from Hungary on 2012-08-06
Patient: 70 year old male
Reactions: Therapeutic Response Decreased, Gastrointestinal Haemorrhage, Mouth Haemorrhage, Haemorrhage, Platelet Count Decreased
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 74 year old male
Reported by a physician from Portugal on 2012-08-06
Patient: 74 year old male, weighing 60.0 kg (132.0 pounds)
Reactions: Therapeutic Response Decreased, Gingival Bleeding, Ecchymosis, Petechiae, Platelet Count Increased, Thrombocytopenia, Epistaxis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Dosage: 490 mug, unk
Nplate
Dosage: 600 mug, qwk
Indication: Thrombocytopenic Purpura
Start date: 2011-12-16
Other drugs received by patient: Rituximab
Possible Nplate side effects in 62 year old male
Reported by a physician from United States on 2012-08-06
Patient: 62 year old male, weighing 91.1 kg (200.4 pounds)
Reactions: Therapeutic Response Decreased, Arthralgia, Treatment Failure
Drug(s) suspected as cause:
Nplate
Dosage: unk
Start date: 2011-11-01
End date: 2012-06-01
Nplate
Dosage: 10 mug, qwk
Indication: Autoimmune Thrombocytopenia
Start date: 2011-11-28
End date: 2012-07-19
Other drugs received by patient: Losartan Potassium
Possible Nplate side effects in 51 year old male
Reported by a consumer/non-health professional from United States on 2012-08-02
Patient: 51 year old male, weighing 160.5 kg (353.2 pounds)
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: Augmentin '125'; Lasix; Immune Globulin NOS; Ambien
Possible Nplate side effects in 56 year old male
Reported by a physician from United States on 2012-08-02
Patient: 56 year old male
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: Lamivudine; Zidovudine; Iron; Tylenol (Caplet); Efavirenz; Folic Acid; Colace
Possible Nplate side effects in 61 year old female
Reported by a physician from United States on 2012-08-01
Patient: 61 year old female, weighing 113.0 kg (248.6 pounds)
Reactions: Therapeutic Response Decreased, Platelet Count Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: Metformin Hydrochloride; Folic Acid; Prednisone; Insulin; Protonix; Sertraline Hydrochloride
Possible Nplate side effects in 65 year old female
Reported by a pharmacist from Spain on 2012-08-01
Patient: 65 year old female, weighing 118.0 kg (259.6 pounds)
Reactions: Therapeutic Response Decreased, Hypersensitivity
Drug(s) suspected as cause:
Nplate
Dosage: unk unk, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2012-03-13
Nplate
Dosage: 236 mug, unk
Start date: 2012-07-12
Nplate
Dosage: unk
Start date: 2011-09-14
End date: 2012-02-23
Nplate
Dosage: unk
Other drugs received by patient: Eltrombopag; Prednisone; Roname; Roname; Tranexamic Acid; Colemin; Sutrilneo; Rituximab; Eltrombopag; Omeprazole; Candesartan Cilexetil; Loratadina; Tramadol HCL; Acetaminophen
Possible Nplate side effects in female
Reported by a physician from United States on 2012-08-01
Patient: female
Reactions: Therapeutic Response Decreased, Drug Ineffective, Platelet Count Decreased
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 40 year old female
Reported by a physician from Spain on 2012-07-24
Patient: 40 year old female
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 29 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-23
Patient: 29 year old male, weighing 76.2 kg (167.6 pounds)
Reactions: Therapeutic Response Decreased, Bone Pain, Platelet Count Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 44 year old female
Reported by a physician from United States on 2012-07-19
Patient: 44 year old female, weighing 87.5 kg (192.5 pounds)
Reactions: Therapeutic Response Decreased, Platelet Count Abnormal
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 50 year old female
Reported by a physician from United States on 2012-07-12
Patient: 50 year old female, weighing 69.9 kg (153.8 pounds)
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Dosage: 62 mug, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2008-09-29
End date: 2009-05-21
Nplate
Dosage: 373 mug/kg, unk
End date: 2009-07-06
Nplate
Dosage: unk
Start date: 2008-10-06
Possible Nplate side effects in
Reported by a physician from United Kingdom on 2012-07-11
Patient:
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 50 year old female
Reported by a physician from United States on 2012-07-09
Patient: 50 year old female, weighing 69.9 kg (153.8 pounds)
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Dosage: unk
Start date: 2008-10-06
Nplate
Dosage: 373 mug/kg, unk
End date: 2009-07-06
Nplate
Dosage: 62 mug, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2008-09-29
End date: 2009-05-21
Possible Nplate side effects in male
Reported by a physician from Canada on 2012-07-09
Patient: male
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: Immune Globulin NOS
Possible Nplate side effects in female
Reported by a physician from United States on 2012-07-05
Patient: female
Reactions: Therapeutic Response Decreased, Injection Site Extravasation, Underdose, Blood Smear Test Abnormal
Drug(s) suspected as cause:
Nplate
Possible Nplate side effects in 62 year old male
Reported by a physician from United States on 2012-07-05
Patient: 62 year old male
Reactions: Therapeutic Response Decreased
Drug(s) suspected as cause:
Nplate
Dosage: 10 mug, qwk
Nplate
Dosage: unk
Indication: Autoimmune Thrombocytopenia
Start date: 2011-11-01
End date: 2012-06-01
Possible Nplate side effects in 53 year old male
Reported by a consumer/non-health professional from United States on 2012-07-04
Patient: 53 year old male, weighing 78.0 kg (171.6 pounds)
Reactions: Therapeutic Response Decreased, Therapeutic Response Unexpected
Drug(s) suspected as cause:
Nplate
Dosage: 500 mug, unk
Start date: 2010-02-04
End date: 2010-02-04
Nplate
Dosage: 510 mug, unk
Start date: 2010-04-08
End date: 2010-04-08
Nplate
Dosage: 672 mug, unk
Start date: 2010-05-06
End date: 2010-05-06
Nplate
Dosage: 850 mug, qwk
Start date: 2010-12-09
End date: 2011-08-04
Nplate
Dosage: 160 mug, unk
Start date: 2010-01-07
End date: 2010-01-07
Nplate
Dosage: 670 mug, qwk
Start date: 2010-10-21
End date: 2010-10-29
Nplate
Dosage: 560 mug, unk
Start date: 2010-02-11
End date: 2010-02-11
Nplate
Dosage: 510 mug, unk
Start date: 2010-04-08
End date: 2010-04-08
Nplate
Dosage: 672 mug, qwk
Start date: 2010-03-18
End date: 2010-04-01
Nplate
Dosage: 250 mug, unk
Start date: 2010-01-14
End date: 2010-01-14
Nplate
Dosage: 320 mug, qwk
Start date: 2010-01-21
End date: 2010-01-21
Nplate
Dosage: 400 mug, unk
Start date: 2010-01-28
End date: 2010-01-28
Nplate
Dosage: 672 mug, qwk
Start date: 2010-02-25
End date: 2010-03-04
Nplate
Dosage: 560 mug, qwk
Start date: 2010-04-15
End date: 2010-04-29
Nplate
Dosage: 9 mug/kg, unk
Start date: 2010-05-13
Nplate
Dosage: 750 mug, qwk
Start date: 2010-05-20
End date: 2010-10-14
Nplate
Dosage: 80 mug, qwk
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2009-12-31
End date: 2009-12-31
Nplate
Dosage: 672 mug, unk
Start date: 2010-05-06
End date: 2010-05-06
Nplate
Dosage: 560 mug, qwk
Start date: 2010-04-15
End date: 2010-04-29
Nplate
Dosage: 750 mug, qwk
Start date: 2010-11-04
End date: 2010-12-02
Other drugs received by patient: Niacin; Tylenol (Caplet); Rituxan; Benadryl; Danazol; Danazol; Zocor
Possible Nplate side effects in 59 year old male
Reported by a pharmacist from United States on 2012-07-02
Patient: 59 year old male, weighing 97.0 kg (213.4 pounds)
Reactions: Therapeutic Response Decreased, Haemolytic Anaemia, Thrombocytopenia, Renal Failure Acute
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nplate
Nplate
Nplate
Nplate
Dosage: 7 mug/kg, unk
Indication: Thrombocytopenia
Start date: 2012-03-16
Nplate
Nplate
Other drugs received by patient: Budesonide; Posaconazole; Prednisone TAB; Atovaquone; Acyclovir
Possible Nplate side effects in 59 year old female
Reported by a pharmacist from United States on 2012-07-02
Patient: 59 year old female, weighing 93.9 kg (206.5 pounds)
Reactions: Diabetes Mellitus, Haemorrhage, Swollen Tongue, Therapeutic Response Decreased, Iron Deficiency Anaemia, Diabetic Neuropathy, Oedema Mouth, Candidiasis
Drug(s) suspected as cause:
Nplate
Other drugs received by patient: Eltrombopag; Corticosteroids
Page 1 Next >>
|